http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_bf5cc40245490ebbb4501d2bce9d7320
Outgoing Links
Predicate | Object |
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family-name | Bo Chen Chen |
name | Bo Chen |
given-name | Bo |
organization-name | School of Acupuncture & Moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin, China; Fourth Teaching Hospital of Tianjin University of TCM Binhai New Area Hospital of TCM Tianjin,Tianjin, China State Key Laboratory of Food Science and Technology, Sino-Germany Joint Research Institute; Nanchang University; Nanchang 330047 China Department of Chemistry Pennsylvania State University University Park PA 16801 USA Dalian Institute of Chemical Physics; The Chinese Academy of Sciences and Dalian National Laboratory for Clean Energy; Dalian 116023; China State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, P. R. China and Shanghai Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, 3663 North Zhongshan Lu, Shanghai 200062, P. R. China Department of Nuclear Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, PR China Beijing Academy of Forestry and Pomology Sciences, Beijing, China; Research Center of Combine Traditional Chinese and Western Medicine, Affiliated Traditional Medicine Hospital of Sichuan Medical University, Luzhou, Sichuan, China Department of Neurosurgery, Xiangyang No.1 People’s Hospital, Hubei University of Medicine Department of Orthopaedics, People's Hospital of Beilun District, the First Affiliated Hospital of Zhejiang University School of Medicine, Ningbo 315800, Zhejiang, China; chenbo80@zju.edu.cn. Department of Orthopedics, Linyi Second People's Hospital, Linyi, China; and National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China; College of Science Huazhong Agricultural University Shizishan Avenue Wuhan 430070 P. R. China Chaohu Hospital Affiliated to Anhui Medical University, Hefei, Anhui Department of Hepatopancreatobiliary Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China State Key Lab of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, 130022, Changchun, China Authors' Affiliations: 1Institute of Oncologic Pathology, Departments of 2Biochemistry and Molecular Biology and 3Experimental Animal Center, Medical College of Shantou University; 4Departments of Pathology, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou, Guangdong; 5Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, Beijing; and 6Key Laboratory of Regenerative Biology, South China Institute of Stem Cell & Regenerative Medicine, Institute of Public Health, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, Qingdao Agricultural University, Qingdao, China. State Key Laboratory of Molecular Oncology and Department of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC) Beijing China; Center for Cancer Precision Medicine CAMS and PUMC Beijing China; National Institute of Biological Sciences Collaborative Innovation Center for Cancer Medicine Beijing China Cynosure, Inc.; Westford Massachusetts Key Laboratory of Hydraulic Machinery Transients of Ministry of Education, School of Power and Mechanical Engineering, Wuhan University, Wuhan, Hubei 430072, China Ministry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University 1 , Haikou 571158, China Plastic Surgery Department, China Japan Friendship Hospital, Beijing, China Institute of Applied Chemistry, College of Chemistry Nanchang University Nanchang Jiangxi 330031 P. R. China Department of Infectious Disease, The First Peoples Hospital of Yancheng, The Fourth Affiliated Hospital of Nantong UniversityJiangsuP. R. China Stem Cells and Nanomaterials Laboratory, School of Chemistry, Food and Pharmacy, University of Reading, Reading, United Kingdom. NSF I/UCRC for Biocatalysis and Bioprocessing of Macromolecules, Polytechnic University, 6 Metrotech Center, Brooklyn, New York 11201, Rohm and Haas Company, P.O. Box 904, Spring House, Pennsylvania 19477 Department of Laboratory Medicine, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, Guangdong, China, Corresponding author: Huang Haiying, Email: 799961191@qq.com. Department of Computer Science and Technology, Tsinghua University , Beijing , China Department of Urology, The Central Hospital of ShenLi Oil Field, China Petrochemical Corporation, Dongying, Shandong, China Institute of Radiation Medicine, Fudan University, Shanghai, China Department of Plastic and Reconstructive Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, People's Republic of China From the Department of Plastic and Reconstructive Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College; the Department of Plastic Surgery, Beijing Hospital, National Center of Gerontology; and the Department of Plastic Surgery, the Second People’s Hospital of Liao Cheng. Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu 610041, China State Key Laboratory of Molecular Oncology,Department of Radiation Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences, and Peking Union Medical College,Beijing,P. R. China Department of Plastic Surgery; Department of Plastic, Cosmetic and Burn Surgery, Shenzhen Hospital of Southern Medical University Department of Anesthesiology, The Hospital of Xidian Group, Xi’an, Shaanxi, China. Department of Breast Cancer, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China. State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, SJTU-NLBP Joint R&D Center on Biopesticides and Biofertilizers, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University (SJTU), Shanghai, China Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, China. wxt1@medmail.com.cn. Department of Physics, University of Central Florida, Orlando, Florida 32816, United States SOA Key Laboratory for Polar Science Polar Research Institute of China Shanghai 200136 China Laboratory of Chemical Physics bobochen.1974@yahoo.com.cn Department of Wound Repair and Rehabilitation Medicine, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Daping Hospital Army Medical University Chongqing China Department of Pathology, Zhejiang Key Laboratory of Diagnosis & Treatment Technology, China. Department of Pathology School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University China Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China Department of Chemistry, Southern University of Science and Technology, Shenzhen 518055, China Department of Atmospheric Sciences, Texas A&M University, Eller O&M Building, 1204, 3150 TAMU, 797 Lamar Street, College Station, Texas 77843, United States Laboratory of Organ Fibrosis Prophylaxis and Treatment by Combine Traditional Chinese and Western Medicine, Research Center of Combined Traditional Chinese and Western Medicine, Affiliated Traditional Medicine Hospital Southwest Medical University Luzhou China; Department of Human Anatomy Southwest Medical University Luzhou China From the Department of Plastic and Reconstructive Surgery, Plastic Surgery Hospital, and the Department of Cardiovascular Surgery, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College; and the Department of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine. Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study; University of South China; Hengyang; China; Hengyang Hospital of Traditional Chinese Medicine School of Public Health, Fudan University. Department of Anesthesiology Chongqing Cancer Institute Chongqing 40030 PR China; Guangxi Medical University Nanning Guangxi 530021 PR China Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, People's Republic of China; and Department of Ophthalmology & Visual Science, Yale University, New Haven, Connecticut, United States Department of Orthopaedics, Rui Jin Hospital, The School of Medicine, Shanghai Jiaotong University, Shanghai Institute of Traumatology and Orthopaedics Shanghai 200025, China. Department of Food Science and Technology, Institute of Food Safety and Nutrition, College of Science & Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, P.R. China; Institute of Microbiology, Guangdong Academy of Sciences, State Key Laboratory of Applied Microbiology Southern China, Guangdong, Guangdong Provincial Key Laboratory of Microbial Safety and Health, Key Laboratory of Agricultural Microbiomics and Precision Application, Ministry of Agriculture and Rural Affairs, Guangzhou 510070, P.R. China Yangtze Delta Region Institute (Huzhou) University of Electronic Science and Technology of China Huzhou 313001 China Department of Applied Chemistry & Biotechnology, Graduate School of Engineering, University of Fukui Department of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of Radiation Oncology, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Center for Clinical Evidence-Based and Translational Medicine, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, China College of Acupuncture-Moxibusiton and Tuina, Tianjin University of TCM. Department of Chemistry; South University of Science and Technology of China; Shenzhen 518055; China Department of Systems Biology, College of Bioinformatics Science and Technology Harbin Medical University China National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China; Department of Microbiology and Molecular Genetics, University of Texas Medical School at Houston, Houston, Texas, USA Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 100083, P. R. China; CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology (NCNST), Beijing 100190, P. R. China Materials Science and Devices Institute; Suzhou University of Science and Technology; Suzhou; China Center for Programmable Materials, School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore Polar Research Institute of China, Shanghai, 200136, China Department of Emergency, the First People's Hospital of Changshu, Changshu 215500, Jiangsu, China. Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, Hunan, 410081, P. R. China Department of Gastrointestinal Surgery, The First Affiliated Hospital of Anhui, Medical University, Hefei, China. Institute of Elemento-Organic Chemistry College of Chemistry Nankai University Tianjin 300071 P. R. China Department of Chemistry, City University of Hong Kong, Hong Kong, 999077, China. State Key Laboratory of Molecular Oncology and Department of Radiation Oncology, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, P. R. China Departments of Ultrasonography, The First Affiliated Hospital of Chongqing Medical University, Chongqing, Sichuan, China XuanZhu Pharma Co., Ltd., Jinan, Shandong, 250101, PR China Department of Vascular Surgery, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China; Shanghai Key Laboratory of Vascular Lesions Regulation and Remodeling, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China Hangzhou Yuhang Sanshui Fruits Co., Ltd Hangzhou China Calcium Signalling Laboratory, Department of Research, National Neuroscience Institute, Singapore, Singapore; Department of Anesthesiology, Chongqing Cancer Institute, China; Guangxi Medical University, China London Centre for Nanotechnology, University College London, London, UK; Research Complex at Harwell, Rutherford Appleton Laboratory, Oxon, UK Center for Programmable Materials School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore Department of Endocrinology, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China Department of Trauma and Orthopaedics Peking University People's Hospital No. 11 South Xizhimen Street Beijing 100044 China School of Materials Science and Engineering Nanyang Technological University 639798 Singapore Qilu Hospital of Shandong University, Jinan, Shandong, China. Key Laboratory of Protein Chemistry and Developmental Biology of the Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha, China Department of Chemistry and Chemical Biology, Baker Laboratory Cornell University Ithaca NY 14853-1301 USA Department of Breast Cancer, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology–Head and Neck Surgery, Boston University School of Medicine, Boston (Drs Levi and Spiegel and Ms Veerappan), and Cynosure, Inc, Westford (Drs Chen, Mirkov, and Sierra), Massachusetts. Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong Qingdao Agricultural University Qingdao 266109 China Calcium Signalling Laboratory, Department of Research, National Neuroscience Institute, Singapore 308433, Singapore State Key Laboratory of Food Science and Technology, Sino−Germany Joint Research Institute, Nanchang University, No. 235 Nanjing East Road, Nanchang 330047, China Department of Hepatobiliary Surgery, Shanghai East Hospital Affiliated to Tongji University, Shanghai 200120, P.R. China College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China Department of Chemistry, Zhejiang Sci-Tech University,Xiasha Campus; Leibniz-Institut für Katalyse e.V. an der Universität Rostock Department of Gastroenterology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P. R. China College of Chemistry and Molecular Sciences Key Laboratory of Biomedical Polymers of Ministry of Education Institute of Molecular Medicine Renmin Hospital of Wuhan University School of Microelectronics Wuhan University Wuhan 430072 P. R. China College of Acupuncture-Moxibustion and Tuina, Tianjin University of TCM, Tianjin 300193, China; Research Center of Experimental Acupuncture Science, Tianjin University of TCM, Tianjin 300193. Department of General Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510182, China School of Mechatronic Engineering, Southwest Petroleum University, Chengdu 610500, China Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Nanjing, China State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology Shanghai Jiao Tong University Shanghai China Key Laboratory of RNA Biology, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China Department of Neurology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College) , Hangzhou , 310014 , Zhejiang China Department of Chemistry, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200241, P. R. China Shanghai Jiao Tong University Department of Plastic and Reconstructive Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research, Ministry of Education, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, Hunan, 410081, People’s Republic of China Translational Medicine Center, Hong Hui Hospital, Xi’an Jiaotong University College of Medicine, Xi’an 710054, China College of Life Science, Gannan Normal University , Ganzhou 341000 , China Department of Breast Cancer, Cancer Center, Guangdong Provincial People’s Hospital and Guangdong Academy of Medical Sciences, Guangzhou, China Department of Physical Education, Beijing University of Chemical Technology , 15 North Third Ring East Road, Chaoyang District , Beijing , 100029 , China School of Biological Sciences, The University of Hong Kong, Pokfulam Road, Hong Kong, Peopleʼs Republic of China; Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), Hunan Normal University, Changsha, Peopleʼs Republic of China; Department of Food Science, Rutgers University, 65 Dudley Road, New Brunswick, New Jersey 08901; and Graduate Institute of Food Science and Technology, National Taiwan University, Taipei, Taiwan Dalian Institute of Chemical Physics, Chinese Academy of Sciences College of Chemistry, Sichuan University, Chengdu 610064, China Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China Department of Breast Cancer, Cancer Center, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China Department of Ultrasonography, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China 1Department of Medicine, Nephrology Research and Training Center and Center for Free Radical Biology Key Laboratory of Hydraulic Machinery Transients (Wuhan University); Ministry of Education; School of Power and Mechanical Engineering; Wuhan University; Wuhan Department of Chemistry City University of Hong Kong 83 Tat Chee Avenue Kowloon Hong Kong China Antarctic Great Wall Ecology National Observation and Research Station, Polar Research Institute of China, Ministry of Natural Resources, Shanghai 200136, China; Key Laboratory for Polar Science, Polar Research Institute of China, Ministry of Natural Resources, Shanghai 200136, China The National & Local Joint Engineering Laboratory of Animal Peptide Drug Development; College of Life Sciences; Hunan Normal University; Changsha; China Gannan Normal University, Ganzhou, Jiangxi, China Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853-1301 Key Laboratory of Phytochemical R&D of Hunan Province and Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education of China), Hunan Normal University, Changsha 410081, China Department of Breast Cancer, Cancer Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, China School of Public Health The First Affiliated Hospital of Anhui Medical University, Anhui Medical University Hefei Anhui China Key Laboratory of Insect Developmental and Evolutionary Biology, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China; CAS Center for Excellence in Biotic Interactions, University of Chinese Academy of Sciences, Beijing, China School of Life Science, Beijing Institute of Technology, Beijing 100081, China. Department of electronic science and technology of USTC, Hefei, Anhui Province, 230026, China. cbapollor@hotmail.com Department of Human Anatomy School of Basic Medical Sciences Southwest Medical University Luzhou China Computation and Neural Systems Program, California Institute of Technology, Pasadena, CA, USA. Kaihua District Center for Disease Control and Prevention Department of Biology, Indiana University, Bloomington, IN 47405; Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin second Road, Shanghai 200025, P. R. China Department of Pharmacology, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China; Chongqing Key Laboratory of Drug Metabolism, Chongqing Medical University, Chongqing 400016, China; Key Laboratory for Biochemistry and Molecular Pharmacology of Chongqing, Chongqing Medical University, Chongqing 400016, China Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy West China Hospital Sichuan University Chengdu 610041 China Dalian National Laboratory for Clean Energy Dalian Institute of Chemical Physics Chinese Academy of Sciences 116023 Dalian Liaoning China School of Materials Science and Engineering; Nanyang Technological University; Singapore 639798, Singapore Department of General Surgery, Qilu Hospital of Shandong University, Jinan 250012, China. College of Chemistry and Chemical Engineering Xiamen University Xiamen 361000 Fujian P. R. China College of Physics and Electronic Information Engineering, Minjiang University, Fuzhou, Fujian 350108, China Department of Clinical Laboratory Medicine The Second Affiliated Hospital of Guangzhou Medical University Guangzhou China Institute of Radiation Medicine, Fudan University 1 , 2094 Xietu Road, Shanghai 200032, China Department of Vascular Surgery, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai 201399, China; Fudan Zhangjiang Institute, Shanghai 201203, China; Shanghai Key Laboratory of Vascular Lesions Regulation and Remodeling, Shanghai, China Sanofi Global R&D 153 Second Avenue Waltham MA 02139 USA School of Mathematical Science, University of Electronic Science and Technology of China , Chengdu 611731, China Department of Nutrition, School of Public Health, Fudan University, Shanghai, China. *College of Fisheries, Huazhong Agricultural University, Wuhan 430070, Hubei, China;; †Hubei Engineering Technology Research Center for Aquatic Animal Diseases Control and Prevention, Wuhan 430070, Hubei, China; Dalian Institute of Chemical Physics, the Chinese Academy of Sciences, Dalian, 116023, People’s Republic of China, Dalian National Laboratory for Clean Energy, People’s Republic of China, and University of Chinese Academy of Sciences, Beijing 100049, People’s Republic of China Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL. National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 301617, China. School of Acupuncture and Moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China. Corresponding author: Chen Bo, Email: tjutcmchenbo@163.com. Chemical Synthesis and Pollution Control Key Laboratory of Si-chuan Province, College of Chemistry and Chemical Engineering, China West Normal University, Nanchong 637002, China Department of Cardiothoracic Surgery, Shanghai Children’s Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine, 1678 Dongfang Road, Shanghai 200127, China. Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California, USA Department of Nephrology, Lianyungang Hospital of Traditional Chinese Medicine, Lianyungang, Jiangsu 222000, P.R. China University of Electronic Science and Technology of China Institute of Materials Science & Devices, Suzhou University of Science and Technology, Suzhou 215009, China Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461 School of Metallurgy Engineering State Local Joint Engineering Research Center for Functional Materials Processing Xi'an University of Architecture and Technology Xi'an 710055 China Unit of Animal Infectious Diseases, National Key Laboratory of Agricultural Microbiology, ‡College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, P.R. China. Center for Programmable Materials; School of Materials Science and Engineering; Nanyang Technological University; Singapore 639798; Singapore Institute of Materials Science and Devices, School of Materials Science and Engineering, Suzhou University of Science and Technology, 99 Xuefu Road, Suzhou215009, Jiangsu, P. R. China Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education of China), Hunan Normal University, Changsha 410081, China; Key Laboratory of the Assembly and Application of Organic Functional Molecules, Hunan Normal University, Changsha 410081, China Research Center of Experimental Acupuncture and Moxibustion Science, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China. tjutcmchenbo@163.com. School of Acupuncture Moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 301617. tjutcmchenbo@163.com. National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381. tjutcmchenbo@163.com. Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China Beijing Academy of Forestry and Pomology Sciences, Beijing, China Department of Chemistry and Center for Advanced Scientific Computing and Modeling, University of North Texas, 1155 Union Circle No. 305070, Denton, Texas 76203-5017, United States Department of Urology; Institution of Urology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China School of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou, 215009, China Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Wangfujing, Beijing, 100730, China Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China. School of Materials Science and Engineering Nanyang Technological University Singapore 639798 50 Nanyang Avenue Singapore Department of Hepatobiliary Surgery The First Affiliated Hospital of Wenzhou Medical University Wenzhou China; Key Laboratory of Diagnosis and Treatment of Severe Hepato‐Pancreatic Diseases of Zhejiang Province The First Affiliated Hospital of Wenzhou Medical University Wenzhou China School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore Department of Chemical Engineering, Tsinghua University, Tsinghua Garden Road 1, 100084 Beijing, China Department of Pharmacology, Third Military Medical University (Army Medical University), Chongqing 400038, China Tianjin Key Laboratory of Film Electronic & Communicate Devices, School of Electrical and Electronic Engineering, Tianjin University of Technology, Tianjin 300384, China Nutrition & Health Research Institute; China National Cereals, Oils and Foodstuffs Corporation (COFCO); Beijing 102209; China; Beijing Key Lab of Nutrition, Health and Food Safety Department of Respiratory Medicine, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, China. State Key Laboratory of Optoelectronic Materials and Technologies, School of Physics, Sun Yat-sen University, Guangzhou 510275, China Key Laboratory of Roadway Bridge and Structural Engineering, Wuhan University of Technology, P.O. Box 219, No. 122 Luoshi Road, Wuhan 430070, China State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China; and College of Food and Bioengineering Zhengzhou University of Light Industry Zhengzhou PR China; Key Laboratory of Cold Chain Food Processing and Safety Control (Zhengzhou University of Light Industry) Ministry of Education Zhengzhou PR China; Henan Food Laboratory of Zhongyuan Zhengzhou University of Light Industry Luohe PR China Experiment Center for Medical Science Research, China Department of Biochemistry UT Southwestern Medical Center 5323 Harry Hines Blvd Dallas TX 75390-9038 USA Department of Physics, National University of Defense Technology, Changsha, Hunan 410073, People’s Republic of China Division of Animal Infectious Disease in the State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, People's Republic of China Division of Nephrology and Nephrology Research and Training Center, University of Alabama at Birmingham, Birmingham, Alabama Key Laboratory of Phytochemical R&D of Hunan Province Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research Ministry of Education Hunan Normal University Changsha P. R. China Center for Stem Cell Research and Application, Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) , Chengdu , China Key Laboratory for Organic Electronics and Information Displays (KLOEID) & Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials (IAM) Jiangsu National Synergistic Innovation Center for Advanced Materials (SICAM) College of Electronic and Optical Engineering & College of Microelectronic Nanjing University of Posts and Telecommunications 9 Wenyuan Road Nanjing 210023 China Tongji University; Key Laboratory of Advanced Civil Engineering Materials (Tongji University) Department of Chemistry and Biochemistry, Florida International University, 11200 SW 8th Street, Miami, Florida 33199 Key Laboratory of Transplant Engineering and Immunology, NHFPC; Regenerative Medicine Research Centre, West China Hospital, Sichuan University, Chengdu, People's Republic of China Department of Mechanical Engineering University of Maryland College Park MD 20742 USA Department of Pediatric Cardiology, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 20092, China Department of Radiology The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University Wenzhou City China Department of Neurosurgery of Wuhan Third Hospital College of Chemistry and Chemical Engineering, China University of Petroleum, Qingdao 266580, China Department of Urology and Institute of Urology and National Clinical Research Center for Geriatrics West China Hospital Sichuan University Chengdu China; West China School of Clinical Medicine Sichuan University Chengdu China School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore Department of Nephrology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; Experiment Center for Medical Science Research, Kunming Medical University, Kunming, Yunnan, PR China Department of Nephrology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China. Plastic Surgery Department, China Japan Friendship Hospital, Beijing, China; Experiment Center for Medical Science Research, Kunming Medical University, Kunming, Yunnan 650500, P.R. China Key Laboratory of Phytochemical R&D of Hunan Province and Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education Hunan Normal University Changsha P. R. China School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai 200032, China; Institute of Nutrition, Fudan University, Shanghai 200032, China Department of Surgical Oncology, The First Affiliated Hospital, China Medical University, Shenyang, 110001, PR China. chbyxlpnt@yahoo.com.cn Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama; School of Materials Science and Engineering; Nanyang Technological University; Singapore 3Institute of Oncologic Pathology, Shantou University Medical College, Shantou, Guangdong, China. Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China West China School of Medicine, Sichuan University, Chengdu 610041, China; Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China State Key Laboratory of Food Science and Technology, Sino-German Joint Research Institute, Nanchang University, No. 235 Nanjing East Road, Nanchang 330047, China Dalian National Laboratory for Clean Energy (DNL); Dalian Institute of Chemical Physics; Chinese Academy of Sciences; Dalian; China Key Laboratory for Advanced Technology in Environmental Protection of Jiangsu Province, Yancheng Institute of Technology, Yancheng 224051, China Department of Chemistry and Biochemistry, Florida International University, 11200 SW 8th Street, Miami, FL 33199; and Department of Human Anatomy and Histoembryology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, China Department of Ophthalmology, UT Southwestern Medical Center, Dallas, Texas, United States; Permanent Address: Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China Shenzhen Entry-Exit Inspection and Quarantine Bureau, 518067, Shenzhen, China Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; College of Acupuncture-moxibustion and Massage, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China. Department of General Surgery, Qilu Hospital of Shandong University, Jinan, China. iHuman Institute School of Life Science and Technology Shanghai Key Laboratory of High‐resolution Electron Microscopy ShanghaiTech University Shanghai China Department of Chemistry City University of Hong Kong Kowloon Hong Kong China NSF I/UCRC for Biocatalysis and Bioprocessing of Macromolecules, Polytechnic Institute of New York University, 6 Metrotech Center, Brooklyn, New York 11201, and Department of Materials Science and Engineering, State University of New York at Stony Brook, Stony Brook, New York 11794-2275 Department of Chemistry and the Center for Advanced, Scientific Computing and Modeling, University of North Texas, 1155 Union Circle, #305070, Denton, Texas 76203-5070, United States Department of Oral and Maxillofacial Surgery, School of Stomatology Peking University Beijing, China. md_bochen@sina.com Department of Medical Imaging, Jingling Hospital, Clinical School of Medical College, Nanjing University, Xuanwu District, Nanjing, Jiangsu Province, PR China Department of Hepatobiliary Surgery The First Affiliated Hospital of Wenzhou Medical University Wenzhou China; Hepatobiliary Pancreatic Tumor Bioengineering Cross International Joint Laboratory of Zhejiang Province The First Affiliated Hospital of Wenzhou Medical University Wenzhou China Department of Orthopedics, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, P.R. China. Department of Hand Surgery, The First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang 310002, P.R. China School of Materials Science and Engineering Suzhou University of Science and Technology Suzhou 215009 P. R. China Nutrition & Health Research Institute, COFCO Corporation, Beijing, China Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu 210096, China; Materials Science and Devices Institute, Suzhou University of Science and Technology, Suzhou, Jiangsu 215009, China Department of Pediatrics, First Affiliated Hospital of Medical College of Shihezi University, Shihezi, Xinjiang 832000, China. lujiaying_2009@163.com. Materials Science and Devices Institute, Suzhou University of Science and Technology, 1 Kerui Road, Suzhou 215009, China Department of Human Anatomy and Histoembryology, School of Basic Medical Sciences Southwest Medical University Luzhou Sichuan 646000 People's Republic of China From Department of Neurosciences (B.C., B.F., Q.C., E.S., P.D.L.), University of California San Diego, School of Medicine, La Jolla Calif; Veterans Administration Medical Center (B.F., Q.C., P.D.L.), San Diego Calif; Department of Physics (P.T., D.K.), University of California San Diego, La Jolla Calif. Experiment Center for Medical Science Research, Kunming Medical University, Kunming 650500, Yunnan, China Department of Chemical Engineering and Division of Bioengineering and Environmental Health, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 Department of Pathogenic Biology, College of Basic Medical Science, China Medical University, Shenyang, Liaoning 110122, P.R. China Department of Nutrition and Food Hygiene, School of Public Health, Key Laboratory of Public Health Safety, Ministry of Education, Fudan University, Shanghai 200032, China. School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou 730050, P. R. China College of Science, National University of Defense Technology 1 , Changsha, Hunan 410073, People’s Republic of China; Hunan Key Laboratory of Extreme Matter and Applications, National University of Defense Technology 2 , Changsha 410073, People’s Republic of China Department of Breast Cancer, Cancer Center, Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences, Guangzhou 510080, Guangdong, China Departments of Biopharmaceutical Sciences and Pharmaceutical Chemistry, School of Pharmacy, University of California, 513 Parnassus Avenue, San Francisco, California 94143-0912, Department of Chemistry, University of California, Berkeley, California 94720-1460, and Department of Biomedical Engineering, Faculty of Engineering, Mahidol University, Nakorn Pathom, Thailand Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China SOA Key Laboratory for Polar Science, Division of Polar Biological Science Polar Research Institute of China 451 Jinqiao Road, Shanghai 200136 China Department of Chemistry and Chemical Biology, Cornell University, Baker Laboratory, Ithaca, New York 14853-1301, United States 2Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, Hunan Normal University, Changsha, Hunan, People’s Republic of China CAS Key Laboratory of Insect Developmental and Evolutionary Biology, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China SINOPEC Dalian Research Institute of Petroleum and Petrochemicals Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, College of Chemistry and Chemical Engineering, China West Normal University, No. 1, Shida Road, Nanchong 637002, P.R. China Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China Department of Pathology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China. Jiangxi Wenir High-Tech Co., Ltd, Yonfeng 330006, China Department of Applied Physical Sciences University of North Carolina Chapel Hill NC 27599 USA Department of Anesthesiology, The Affiliated Hospital of Guizhou Medical University, Guiyang, P. R. China Faculty of Environmental Science and Engineering; Kunming University of Science and Technology; Kunming 650500; P. R. China Translational Medicine Center, Hong Hui Hospital Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, People’s Republic of China Department of Pathophysiology, First Military Medical University, Guangzhou 510515, China. College of Science Huazhong Agricultural University Wuhan 430070 P. R. China Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai China Department of Physics, ‡Biotechnology Graduate Program, and ∥Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, United States School of Transportation and Civil Engineering and Architecture, Foshan University, Foshan 528000, China Department of Radiology, The Second Affiliated Hospital and Yuying Children's Hospital Wenzhou Medical University Wenzhou China Department of Pathophysiology, Key Laboratory for Shock and Microcirculation Research of Guangdong, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China Department of Cardiology, The Third Hospital of Jinan, Jinan, Shandong, China (mainland) Perotech, Inc., Chapel Hill, NC 27516, USA. Department of Plastic and Reconstructive Surgery, Plastic Surgery Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China Center for Programmable Materials School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue, Singapore 639798 Singapore Department of General Surgery, First Affiliated Hospital of Anhui Medical University, Hefei, China Center for Programmable Materials School of Materials Science and Engineering Nanyang Technological University Singapore 639798 Singapore Department of Rehabilitation MedicineCenter of Bone Metabolism and Repair, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma CenterResearch Institute of Surgery, Daping HospitalThird Military Medical UniversityChongqingChina College of Biology and Food Engineering, Huaihua University, Huaihua, China.; Key Laboratory of Research and Utilization of Ethnomedicinal Plant Resources of Hunan Province, College of Biological and Food Engineering, Huaihua University, Huaihua, China. Department of Implantology, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, No. 22, Zhongguancun South Avenue, Haidian District, Beijing 100081, China Department of Mechanical and Materials Engineering and Nebraska Center for Materials and Nanoscience University of Nebraska‐Lincoln Lincoln NE 68588‐0656 USA Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China; West China School of Medicine, Sichuan University, Chengdu, Sichuan 610041, China Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education; College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China Department of Gastrointestinal Surgery, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen, P.R. China. Department of Environmental Science, East China Normal University, Shanghai 200062, China. bchen922@263.net Key Laboratory of Roadway Bridge and Structural Engineering, Wuhan University of Technology, Wuhan 430070, China Department of Orthopedic, People's Hospital of Rizhao, Rizhao, Shandong 276800, P.R. China Department of Endocrinology Guangdong Second Provincial General Hospital Guangzhou China Department of Urology, West China Hospital of Sichuan University, No. 37, Guoxue Lane, Chengdu 610041, China; Institute of Urology, West China Hospital of Sichuan University, Chengdu 610041, China CAS Key Laboratory of Synthetic Chemistry of Natural Substances, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China Institute of Materials Science and Devices, School of Materials Science and Engineering, Suzhou University of Science and Technology, 99 Xuefu Road, Suzhou, 215009, Jiangsu, P. R. China Stem Cells & Nanomaterials Laboratory, Reading School of Pharmacy, Hopkins Building, University of Reading, Berkshire, RG6 6UB, UK From the Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA. Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, PR China b State Key Laboratory for Diagnosis and Treatment of Infectious Diseases and Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Key Laboratory of Molecular Nanostructures and Nanotechnology, Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences (CAS), Beijing 100080, People’s Republic of China, and Graduate School of Chinese Academy of Sciences, Beijing 100080, People’s Republic of China NSF I/UCRC for Biocatalysis and Bioprocessing of Macromolecules, Polytechnic University, 6 Metrotech Center, Brooklyn, New York 11201, and Rohm and Haas Co., P.O. Box 904, Spring House, Pennsylvania 19477 Shanghai Key Laboratory for Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 197 Second Ruijin Road, Shanghai 200025, China Key Laboratory of Transplant Engineering and Immunology, National Health and Family Planning Commission (NHFPC), West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China Breast Division, The First Hospital of China Medical University, Shenyang 110001, Liaoning, People's Republic of China Department of Stomatology, Jinling Hospital, Nanjing Medical University, Nanjing, Jiangsu, China College of Acupuncture and Moxibustion, Tianjin University of TCM, Tianjin 300193, China. tjutcmchenbo@163.com Department of Breast Surgery, First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China State Key Laboratory Breeding Base of Eco-Environments and Bio-Resources of the Three Gorges Reservoir Region, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, People’s Republic of China; Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming 650500, People’s Republic of China Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, P. R. China, and Shanghai Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, 3663 North Zhongshan Lu, Shanghai, 200062, P. R. China Department of Biostatistics Princess Margaret Cancer Centre Toronto Ontario Canada School of Materials Science and Engineering Nanyang Technological University Singapore 639798 Singapore College of Environmental Science and Engineering, Guilin University of Technology, Guilin, People’s Republic of China Jiangsu Provincial Key Laboratory of Geriatrics, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China Department of Biochemistry and Molecular Biology & Institute of Oncologic Pathology, Shantou University Medical College, Shantou, P.R.China Department of Nephrology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; Institute of Chronic Kidney Disease, Wenzhou Medical University, Wenzhou, China Department of Breast Surgery, The First Affiliated Hospital of China Medical University, Shenyang, China Dynamic Optical Microscopic Imaging Laboratory, Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, 410082, China Clinical Laboratory Medicine Department, The Second Affiliated Hospital of Guangzhou Medical University , Guangzhou 510260, P. R. China Polymer & Biomaterial R&D, Sanofi-Genzyme R&D Center, Genzyme Corporation—A Sanofi Company, 270 Albany Street, Cambridge, Massachusetts 02139, United States Plastic Surgery Department, China-Japan Friendship Hospital, Beijing, PR China; Dynamic Optical Microscopic Imaging Laboratory, Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Key Laboratory of Phytochemical R&D of Hunan Province, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, Hunan 410082, People’s Republic of China Department of Chemistry, Innovative Drug Research Center, Shanghai University, Shanghai, 200444, P. R. China Department of Breast Surgery, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China SOA Key Laboratory for Polar Science, Polar Research Institute of China, Shanghai, People's Republic of China Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC), Chengdu 610052, China School of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou 215009, China Stanford University Energy Resources Engineering Department, , Stanford, California 94305-4007, USA Department of Plastic Surgery, Peking Union Medical College Hospital Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People's Republic of China; Department of Plastic, Cosmetic and Burn Surgery Shenzhen Hospital of Southern Medical University, Shenzhen, People's Republic of China Shenzhen Key Lab of Nano-Micro Material Research; School of Chemical Biology and Biotechnology; Shenzhen Graduate School of Peking University; Shenzhen, China Wuhan Leishenshan Hospital Wuhan China; Clinical Trial Center Zhongnan Hospital of Wuhan University Wuhan China Institute of Materials Science and Devices School of Materials Science and Engineering Suzhou University of Science and Technology 99 Xuefu Road Suzhou 215009 Jiangsu P. R. China Department of Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.; Shanghai Key Laboratory of Tissue Engineering Research, National Tissue Engineering Center of China, Shanghai, People's Republic of China. Department of Chemistry and Center for Nanoscale Science and Technology, MS 222, Rice University, 6100 Main Street, Houston, Texas 77005 Department of Radiation Oncology, Cancer Hospital, CAMS and PUMC, Beijing 100021, China. State Key Laboratory of Fine Chemicals, Chemical Engineering Department, Dalian University of Technology Linggong Road 2#, Dalian 116024, China State Key Laboratory of Polymer Physics and Chemistry; Changchun Institute of Applied Chemistry; Chinese Academy of Sciences; Changchun; P. R. China CAS Center for Excellence in Nanoscience, Beijing Key Laboratory of Micro-Nano Energy and Sensor, Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 100083, P. R. China; School of Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing 100049, P. R. China Sanofi-Genzyme R&D Center, Genzyme Corporation, A Sanofi Company, Framingham, Massachusetts 01701, United States Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Department of Materials Science and Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, United States Nursing Department, The Second Affiliated Hospital of Soochow University, Suzhou, China Department of Hematology/Oncology, Children's Hospital of Chongqing Medical University, Chongqing 400014, China. yujie167@yahoo.com. Center for Programmable Materials School of Materials Science and Engineering 50 Nanyang Avenue Singapore 639798 Singapore Department of Chemistry and Center for Advanced Scientific Computing and Modeling (CASCaM), University of North Texas, 1155 Union Circle, #305070, Denton, Texas 76203-5070, United States Department of Urology, Xuzhou Central Hospital, Xuzhou, PR China Department of nephrology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China Department of Oral Implantology Peking University School and Hospital of Stomatology Beijing China Shi's Medicine Center of Orthopedics and Traumatology, Shuguang Hospital Affiliated to Shanghai University of TCM, Shanghai 201203, China. cbm818@126.com. Institute of Traumatology and Orthopedics, Shanghai Academy of TCM, Shanghai 201203. cbm818@126.com. Department of Head and Neck Surgery, Institute of Cancer and Basic Medicine (ICBM), Chinese Academy of Sciences, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, No.1 East Banshan Road, Hangzhou 310022, Zhejiang Province,China ICU, Daqing Longnan Hospital, Daqing, People’s Republic of China State Key Laboratory of Food Science and Technology, Sino-Germany Joint Research Institute, Nanchang University, No. 235 Nanjing East Road, Nanchang 330047, China Contribution from the Department of Chemistry, Smalley Institute for Nanoscale Science and Technology, Rice University, MS-222, 6100 Main Street, Houston, Texas 77005 College of Life Science, China West Normal University, Nanchong, China School of Materials Science and Engineering Tongji University Shanghai 201804 China Clinical Immunology Center of PLA, Shanghai, China Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research, Ministry of Education, Key Laboratory of Phytochemical R&D of Hunan Province, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, Hunan 410081, China Department of Radiation Oncology Cancer Hospital Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC) Beijing China Department of Biliary and Pancreatic Surgery, East Hospital Affiliated to Tongji University in Shanghai, Shanghai, China. Shuguang Hospital Affiliated to Shanghai University of Traditional, Chinese Medicine, Shanghai 201203, P. R. China Clinical Department, Keymed Biosciences (Chengdu) Limited, Chengdu, Sichuan 610219, China. Department of Plastic and Reconstructive Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Shijingshan District, Beijing, China Department of Chemistry of Natural Products, School of Pharmacy, Fudan University, Shanghai 200032, People's Republic of China Center for Clinical Evidence‐Based and Translational Medicine Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science Xiangyang China School of Public Health, Fudan University, Shanghai, China Department of Neurosurgery, People's Hospital Affiliated to Jiangsu University, Zhenjiang, Jiangsu Province, China Wenir Nutrition High‐Tech Co., Ltd Yongfeng China Institute of Translational Medicine, School of Pharmaceutical Sciences, Nanjing Tech University Nanjing, Jiangsu Province, 210009, China ; Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Georgia Regents University Augusta, GA, 30912, USA. Research Institute of Chemical Defense, Beijing 100191, China Department of Radiology; Shanghai East Hospital; Tongji University School of Medicine; Shanghai 200120; P. R. China Central Laboratory, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China. Zhejiang University, Department of Horticulture, Hangzhou, Zhejiang, China. 1Department of Breast Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, China.; 2Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China. State Key Laboratory of NBC Protection for Civilian, Beijing 102205, China; Laboratory of Analytical Chemistry, Institute of Chemical Defence, Beijing 102205, China National Energy R&D Center for Biorefinery; Beijing University of Chemical Technology; Beijing 100029; PR China a Chemical Research Institute , Hunan Normal University , Changsha , 410081 , P.R. China Department of Urology, Affiliated Hospital of Chengdu University, Chengdu, Sichuan, China Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China School of Life Science and Engineering, Lanzhou University of Technology, The Key Lab of Screening, Evaluation and Advanced Processing of TCM and Tibetan Medicine, Gansu Educational Department, No. 287, Langongping Road, Qilihe District, Lanzhou 730050, Gansu, China School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China Department of Thyroid and Breast Surgery, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, P.R. China. Department of Public Health, Fudan University, Shanghai 200032, China. Department of Neurology, Hunan Children’s Hospital, Changsha, China Department of Biostatistics, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada; Department of Plastic and Reconstructive Surgery Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China SOA Key Laboratory for Polar Science, Polar Research Institute of China , Shanghai, China State Key Lab of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130022, China. Leibniz-Institut für Katalyse e.V.an der Universität Rostock, Albert-Einstein-Straße 29a, 18059 Rostock, Germany Department of Breast Oncology, Sun Yat‑sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong 510060, P.R. China Department of Electrical and Computer Engineering, Duke University, Durham, NC 27710, USA. School of Materials Science and Engineering, Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore; Environmental Chemistry and Materials Group, Nanyang Environment and Water Research Institute, Interdisciplinary Graduate School, Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore Dalian National Laboratory for Clean Energy Dalian Institute of Chemical Physics Chinese Academy of Sciences 116023 Liaoning Dalian China National Laboratory of Solid State Microstructures School of Physics Nanjing University Nanjing 210093 China Division of Breast Surgery, Department of Surgical Oncology, General Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China Translational Medicine Center, Honghui Hospital Xi'an Jiaotong University Xi'an China State Key Laboratory of NBC Protection for Civilian, Beijing 102205, China Laboratory of Wound Repair and Rehabilitation, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Daping Hospital Army Medical University Chongqing 400042 China Key Laboratory of Phytochemical R&D of Hunan Province, and Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education), and Key Laboratory of the Assembly and Application of, Organic Functional Molecules of Hunan Province Hunan Normal University Changsha 410081 China Sanofi- Genzyme, GDB, Cambridge, MA, 02139, USA Institute of Urology, West China Hospital of Sichuan University, Chengdu, Sichuan 610041, China. Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education of China); Key Laboratory of Phytochemical R&D of Hunan Province; Hunan Normal University; Changsha PR China Department of Emergency, The 940th Hospital of Joint logistics Support Force of People’s Liberation Army, Lanzhou, China; Colorectal Cancer Surgery Department of Radiology, East Hospital, Tongji University School of Medicine, Shanghai, China. Department of Bioengineering, University of Texas at Arlington, Arlington, Texas 76010, United States Experiment Center for Medical Science Research, Kunming Medical University, Chenggong District, Kunming 650500, Yunnan, PR China Department of Clinical Laboratory, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China; Department of Nuclear Medicine, Chaohu Hospital Affiliated to Anhui Medical University, Hefei, Anhui, China Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China (Z.D., C.L., R.H., J.T., W.Z., T.W., X.G., Z.T., Z.X., Y.L., B.C., X.K., C.L.). Experimental Research Center of Acupuncture, Tianjin University of TCM, Tianjin 300193, China. Department of Radiation Oncology NCC/NCRCC/Cancer Hospital CAMS & PUMC Beijing China Department of Orthopedics, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China Department of Radiology, The Second Hospital Dalian Medical University Dalian China Department of Pathology, Zhejiang Cancer Hospital, Hangzhou, Zhejiang 310022, P.R. China London Centre for Nanotechnology, University College London, London WC1H 0AH, UK.; Research Complex at Harwell, Harwell Oxford, Didcot, Oxfordshire OX11 0FA, UK.; School of Materials Science and Engineering, Tongji University, Shanghai 201804, China. Institute of Orthopaedics and Traumatology, Shanghai 200025, China. College of Materials Science and Engineering, Nanjing Tech University, Nanjing 211800, China Departments of Ultrasonography, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China Department of Orthopedics, The People’s Hospital of China Three Gorges University, The First People’s Hospital of Yichang, Yichang City, Hubei, China Beijing National Laboratory for Molecular Sciences, Key Laboratory of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, People's Republic of China, and Institute of Botany, Chinese Academy of Sciences, Beijing 100093, People's Republic of China Acu-moxibustion and Tuina Department, Tianjin University of Traditional Chinese Medicine , Tuanbo, Jinghai, Tianjin , China Key Laboratory of Public Health Safety, Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China. Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics 2 , Mianyang 621900, China Research Institute of Orthopaedics and Traumatology, Shuguang Hospital Affiliated to Shanghai, University of Traditional Chinese Medicine, Shanghai, China School of Acupuncture-Moxibustion and Tuina, Guiyang TCM College. State Key Laboratory of Tea Plant Biology and Utilization; Anhui Agricultural University; Hefei 230036; China Department of Breast Surgery, The First Hospital of China Medical University, Shenyang, China Forestry and Pomology Institute, Beijing Academy of Agriculture and Forestry Sciences/Horticulture Ecological Environment Function Promoted Collaborative Innovation Center, Beijing 100093, China. Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China Department of Surgical Oncology, First Affiliated Hospital, China Medical University, Shenyang 110001, China. chbyxl@hotmail.com College of Acupuncture and Massage, Guiyang College of Traditional Chinese Medicine , Guiyang , China State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China Co-operation and Co-construction Support Department, Guangzhou KingMed Center for Clinical Laboratory Co., Ltd., Guangzhou, Guangdong 510030, P.R. China School of Dentistry, Tianjin Medical University, Tianjin 300070, China Department of Chemistry, City University of Hong Kong, Kowloon, Hong Kong SAR 999077, China Acupuncture-Moxibustion and Tuina College of Tianjin University of TCM, Tianjin 300193, China; Pilot Unit of Acupuncture and Moxibustion Standardization of State Administration of TCM of China, Tianjin 300193. Department of Thyroid Surgery, Qilu Hospital of Shandong University, Jinan, China School of Pharmaceutical and Chemical Engineering, Taizhou University, Jiaojiang, Taizhou 318000, Zhejiang, China National Engineering Research Center for Colloidal Materials Shandong University Jinan 250100 P.R. China Development Research Center, China Geological Survey, Beijing 100037, China Department of Microbiology & Molecular Genetics, University of Texas McGovern Medical School, Houston, TX 77030 Authors' Affiliations: 1Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center; 2Program in Genes & Development, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; 3Department of Surgical Oncology, the First Affiliated Hospital, China Medical University, Shenyang, Liaoning, PR China; 4Department of Oncology, Chi-Mei Medical Center, Tainan, Taiwan; Departments of 5GI Medical Oncology, 6Pathology, 7General Internal Medicine, Ambulatory Treatment, and Emergency Care, 8Endocrine Neoplasia and Hormonal Disorders, and 9Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; Authors' Affiliations: 1Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center; 2Program in Genes & Development, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; 3Department of Surgical Oncology, the First Affiliated Hospital, China Medical University, Shenyang, Liaoning, PR China; 4Department of Oncology, Chi-Mei Medical Center, Tainan, Taiwan; Departments of 5GI Medical Oncology, 6Pathology, 7General Internal Medicine, Ambulatory Treatment, and Emergency Care, 8Endocrine Neoplasia and Hormonal Disorders, and 9Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research Ministry of Education Hunan Normal University Changsha China Department of Urology, West China Hospital of Sichuan University, No. 37, Guoxue Lane, Chengdu 610041, China Department of Gastroenterology, Children's Hospital Zhejiang University School of Medicine, National Clinical Research Center for Child Health Hangzhou China Department of Orthopedics Zhongnan Hospital of Wuhan University Wuhan China Laboratory of Organ Fibrosis Prophylaxis and Treatment by Combine Traditional Chinese and Western Medicine, Research Center of Combine Traditional Chinese and Western Medicine, Affiliated Traditional Medicine Hospital of Southwest Medical University, Luzhou, China; CAS Key Laboratory of Insect Developmental and Evolutionary Biology, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China; CAS Center for Excellence in Biotic Interactions, University of Chinese Academy of Sciences, Beijing, China *Basic Research Laboratory, Shanxi Key Laboratory of Otorhinolaryngology, Head and Neck Cancer, Taiyuan, Shanxi, China.; Department of Otolaryngology, Head & Neck Surgery, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; The Key Scientific and Technological Innovation Platform for Precision Diagnosis and Treatment of Head and Neck Cancer, Taiyuan, Shanxi, China. Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, Hunan Normal University, Changsha 410081, People’s Republic of China NSF I/UCRC for Biocatalysis and Bioprocessing of Macromolecules, Polytechnic University, 6 Metrotech Center, Brooklyn, New York 11201, Rohm and Haas Co., P.O. Box 904, Spring House, Pennsylvania 19477, and National Synchrotron Light Source, Brookhaven National Laboratory, Upton, New York 11973 Department of Cardiology, The Fourth People's Hospital of Jinan, Medical School, Tai Shan Medical College, Jinan, P.R. China. Biotechnology Center, Nutrition & Health Research Institute COFCO Corp. Beijing China; Beijing Key Laboratory of Nutrition & Health and Food Safety Beijing Engineering Laboratory for Geriatric Nutrition Food Research Beijing China Department of Breast Cancer, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research, Ministry of Education of China, College of Chemistry and Chemical Engineering, Hunan Normal University, No. 36, Lushan Road, Changsha, China 410081 Department of Critical Care Medicine, Shangluo Central Hospital, Shangluo, Shaanxi 726000, P.R. China Institute of Advanced Studies and School of Pharmaceutical and Chemical Engineering, Taizhou University, Jiaojiang 318000, Zhejiang, China Department of Plastic and Reconstructive Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing PR China Key Laboratory of Public Health Safety of Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, School of Public Health, Fudan University, Shanghai, China Department of Biostatistics, Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada Department of Radiation Oncology, Southern Medical University, Guangzhou, China. helen866909@163.com 1Department of Breast Cancer, Cancer Center, Guangdong Provincial People’s Hospital and Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou 310018, People’s Republic of China; Leibniz-Institut für Katalyse e. V. an der Universität Rostock, Albert-Einstein-Straβe 29a, 18059 Rostock, Germany Department of Orthopaedics and Traumatology Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong China; Shanghai Key Laboratory for Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Shanghai Ruijin Hospital Shanghai Jiaotong University School of Medicine Shanghai 200000 China Center for Energy Harvesting Materials and System, Virginia Tech, Blacksburg, Virginia 24061, United States Department of Bioengineering, University of Texas at Arlington, Arlington, Texas 76019, United States Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China. Key Laboratory for Polar Science of State Oceanic Administration, Polar Research Institute of China, Shanghai, People’s Republic of China Department of Applied Physical Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Changshu First People’s Hospital Affiliated to Soochow University, Changshu, Jiangsu, China Departments of Developmental and Molecular Biology and Obstetrics, Gynecology and Women’s Health, Center for the Study of Reproductive Biology and Women’s Health, Albert Einstein College of Medicine, New York, New York 10461 College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China (mainland) State Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, China State Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, China Dynamic Optical Microscopic Imaging Laboratory, Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, Key Laboratory of Phytochemical R&D of Hunan Province, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, Hunan 410081, P. R. China Department of Chemistry, City University of Hong Kong, Hong Kong, China Department of Breast Cancer, Cancer Center, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences , Guangzhou, Guangdong, China Institute of Advanced Optoelectronic Materials and Technology, College of Big Data and Information Engineering, Guizhou University, Guiyang 550025, China Department of Chemistry City University of Hong Kong Hong Kong 999077 P. R. China Department of Orthopaedics, 987 Hospital of Peoples Liberation Army of China Joint Logistics Support Force, Baoji, Shaanxi 721004, P.R. China Department of Traditional Chinese Medicine Qingdao Huangdao District Central Hospital Qingdao China School of Ophthalmology and Optometry and Eye hospital, Wenzhou Medical University, Wenzhou, Zhejiang, P.R. China; the Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China Nanyang Environment and Water Research Institute (NEWRI) Nanyang Technological University 1 Cleantech Loop, CleanTech One Singapore 637141 Singapore; Interdisciplinary Graduate School (IGS) Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore; School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore Department of Chemistry; Zhejiang Sci-Tech University; Hangzhou 310018; People's Republic of China From the Plastic Surgery Department, China Japan Friendship Hospital, Beijing, China. Core Laboratory of Glycobiology and Glycoengineering, College of Basic Medical Sciences Dalian Medical University Dalian China Institute of Oncologic Pathology, Medical College of Shantou University; The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College Sanofi Global R&D; Waltham; USA Plastic Surgery Department China Japan Friendship Hospital Beijing China Department of Breast Surgery The First Hospital of China Medical University Shenyang Liaoning 110001 China Department of Plastic and Reconstructive Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China Department of Endocrinology, Guangdong Second Provincial General Hospital , Guangzhou, China Department of Breast Surgery the First Hospital of China Medical University Shenyang Liaoning 110001 China Wenzhou Medical University, Wenzhou, Zhejiang, China (mainland) Third Department of Orthopaedics, the General Hospital of Armed Police Forces of Zhejiang, Jiaxing 314000, Zhejiang, China. Laboratory of Molecular Recognition and Synthesis, Department of Chemistry, Zhejiang University, Hangzhou 310027, Zhejiang, P. R. China College of Acupuncture-Moxibustion and Tuina, Tianjin University of CM, Tianjin 300193. School of Metallurgy Engineering National and Local Joint Engineering Research Center for Functional Materials Processing Xi'an University of Architecture and Technology Xi'an 710055 China Department of Urology / Research Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China. Chengdu WestChina-Frontier Pharmatech Co., Chengdu 610041, China Faculty of Agriculture, Forestry and Food Engineering, Yibin University, Yibin, Sichuan, China Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Department of Breast Cancer, Cancer Center, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, 510080, China Department of Urology, Gaozhou People's Hospital, Gaozhou, Guangdong, China Department of Bone Diesase and Bone Tumor, Hong Hui Hospital, Xi’an Jiaotong University College of Medicine, Shaanxi 710054, China College of Civil Engineering, Fuzhou University, Fuzhou 350116, China Department of Hepatobiliary East Hospital Affiliated to Tongji University Shanghai China Department of Neurosurgery, Xiangya Hospital Central South University Changsha China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University Changsha China Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078. The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development College of Life Sciences Hunan Normal University Changsha Hunan China; The Key laboratory of Protein Chemistry and Developmental Biology of Ministry of Education College of Life Sciences Hunan Normal University Changsha Hunan China Department of Center for Translational Medicine, Keymed Biosciences Inc, Chengdu, Sichuan, China Nephrology Division, University of Alabama, Birmingham, Alabama State Key Laboratory of Bioelectronics; School of Biological Science and Medical Engineering; Southeast University; Nanjing 210096; China Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education of China) Key Laboratory of Application and Assemble of Organic Functional Molecules Hunan Normal University Changsha 410081 China School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China Center for Stem Cell Research and Application, Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC), Chengdu 610052, China Department of Cardiovascular, First People’s Hospital of Jiashan County, Jiaxing, Zhejiang Province, China Department of Urology Xuzhou Clinical School of Xuzhou Medical College The Affiliated Xuzhou Center Hospital of Nanjing University of Chinese Medicine Xuzhou Central Hospital Xuzhou China Department of Atmospheric Science, Texas A&M University, College Station, Texas 77843, United States Department of Orthopedics, The Second Hospital of Jilin University, Jilin University, Changchun 130041, PR China Department of Neurosurgery, Shaanxi Provincial People's Hospital, No. 256 West Youyi Road, Xi'an, 710068, Shaanxi, China Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou 310018, People’s Republic of China; Leibniz-Institut für Katalyse e. V. an der Universität Rostock, Albert-Einstein-Straße 29a, 18059 Rostock, Germany Baker Laboratory, Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States Spinal and Trauma’s Ward, The Third People Hospital of Dalian, Dalian City, 116000, China Fudan Zhangjiang Institute College of Physics and Optoelectronics; Taiyuan University of Technology; Taiyuan 030024; P. R. China; Key Laboratory of Advanced Transducers and Intelligent Control System Department of Radiation Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Materials Science and Devices Institute Suzhou University of Science and Technology 1 Kerui Road Suzhou 215009 China School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore School of Basic Medical Sciences, Guangdong Medical University, Dongguan, Guangdong 523808, P.R. China Dynamic Optical Microscopic Imaging Laboratory, Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, Key Laboratory of Phytochemical R&D of Hunan Province, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, Hunan 410081, People’s Republic of China Department of Nutrition and Food Hygiene, Key Laboratory of Public Health Safety of Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China. Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, Key Laboratory of Phytochemical R&D of Hunan Province, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, Hunan 410081, China Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Environmental Science Hebei University Baoding, Hebei 071002 P.R. China Fudan University 1 Institute of Radiation Medicine, , 2094 Xietu Road, Shanghai 200032, China Departments of Chemistry, Computer Science, Mechanical Engineering and Materials Science, and the Smalley Institute for Nanoscale Science and Technology, Rice University, Houston, Texas 77005, Department of Physics and Astronomy, University of Rochester, Rochester, New York 14627, and Department of Inorganic and Analytical Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel Department of Chemistry, University of Science and Technology of China, Hefei 230026, China Ultrasonography Department, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. China Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln, Lincoln, Nebraska 68588-0526, United States Department of Chemistry, City University of Hong Kong, Hong Kong SAR 999077, P. R. China Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States Department of Chemistry, East China Normal University, Shanghai 200062, People's Republic of China, and Department of Chemistry, Zhoukou Normal University, Zhoukou 466001, People's Republic of China Agilent Technology (China) Co. Ltd., Shanghai, 201008, China College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036, China. Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China Department of Ophthalmology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, Guangdong, P.R. China; Institute of Oncologic Pathology, Shantou University Medical College, Shantou, Guangdong, P.R. China Department of Breast Oncology, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center of Cancer Medicine, Guangzhou, China Tianjin Research Center for Experimental AcupunctologyTianjin University of Traditional Chinese Medicine, Tianjin 301617, China; College of Acupuncture-moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, the first Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381. National Laboratory of Solid State Microstructures Collaborative Innovation Center of Advanced Microstructures Department of Physics Nanjing University Nanjing 210093 China 2Key Laboratory of Public Health Safety of Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, School of Public Health, Fudan University, Shanghai, China Center for Programmable Materials, School of Materials Science and Engineering, Nanyang Technological University, Singapore 639798, Singapore Department of Plastic and Reconstructive Surgery Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100730 People's Republic of China Departments of Radiation Oncology and Dalian Institute of Chemical Physics, the Chinese Academy of Sciences, Dalian, 116023, People’s Republic of China; Dalian National Laboratory for Clean Energy, the Chinese Academy of Sciences, Dalian, 116023, People’s Republic of China Department of Rheumatology and Immunology, West China Hospital Sichuan University Chengdu China Graduate Institute of Molecular and Comparative Pathobiology, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan State Key Laboratory of Molecular Oncology and Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States; Department of Chemistry and Chemical Biology, Cornell University, Baker Laboratory, Ithaca, New York 14853, United States; Donostia International Physics Center, Paseo Manuel de Lardizabal, 4, 20018 Donostia, San Sebastian, Spain; Basque Foundation for Science, Maria Diaz de Haro 3, 48013 Bilbao, Spain Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing 100190, China; School of Engineering Science, University of Chinese Academy of Sciences, Beijing 100190, China Department of Bioengineering, Therapeutic Sciences and Pharmaceutical Chemistry, University of California, San Francisco, California 94143-0912, United States State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, P. R. China, Shanghai Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, 3663 North Zhongshan Lu, Shanghai 200062, P. R. China, and Laboratory of Molecular Recognition and Synthesis, Department of Chemistry, Zhejiang University, Hangzhou 310027, Zhejiang, P. R. China Department of Human Anatomy, Southwest Medical University, Luzhou, China; Department of Ultrasonography The First Affiliated Hospital of Chongqing Medical University Chongqing China College of Environment, Zhejiang University of Technology, Hangzhou 310014, China Experiment Center for Medical Science Research, Kunming Medical University, Kunming, Yunnan, China Department of Gastroenterology, QiLu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, China Department of Gastrointestinal Surgery, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen, China; Teaching and Research Section of Surgery, The First Clinical College of Fujian Medical University, Fuzhou, China Department of Hepatopancreatobiliary Surgery, East Hospital Affiliated to Tongji University in Shanghai, Shanghai, China (mainland) Zhejiang Chinese Medical University, Hangzhou 310053, China. 1Department of Surgical Oncology, Breast Surgery, General Surgery, First Affiliated Hospital of China Medical University, Shenyang, China Department of Chemistry City University of Hong Kong Hong Kong China Department of Orthopedics, The Second Hospital of Jilin University, Changchun, Jilin Province, China Department of Radiation Oncology National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College Beijing China College of Acupuncture and Tuina, Guizhou University of Traditional Chinese Medicine, Dongqing South Road, Guiyang, Guizhou 550025, P. R. China Zhenjiang Institute for Drug Control, Zhenjiang 212000, P. R. China State Key Laboratory of Molecular Oncology, Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China Department of Plastic and Reconstructive Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and, Peking Union Medical College, Beijing, People’s Republic of China Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA Department of Cardiovascular Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China College of Veterinary Medicine, Yangzhou University, Yangzhou, China Guiyang College of TCM, Guizhou 550002, China. chenbomed@yahoo.com.cn Division of Diagnostic Imaging, Department of Nuclear Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA Department of Organic Chemistry; Weizmann Institute of Science; Rehovot; Israel 76100 Beijing 3D Printing Orthopedic Application Engineering Technology Research Center Beijing China School of Mechanical Engineering and Automation Beihang University Beijing 100191 China College of Environment and Plant Protection, Hannan University, Haikou 570028, China. yiluo.feeling@qq.com Department of Hepatopancreatobiliary Surgery, East Hospital Affiliated to Tongji University, Shanghai 200123, China Bio-inspired Materials and Devices Laboratory (BMDL), Center for Energy Harvesting Materials and Systems (CEHMS), Virginia Tech, Blacksburg, Virginia 24061, United States Changchun Institute of Biological Products Co. Ltd. Changchun P.R. China Department of Breast Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 651 East Dongfeng Road, Guangzhou, 510060, China Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China. Department of Chemistry, University of California, Riverside, California 02521, United States From the Division of Biological Sciences (B.C., K.Y.) and the Department of Neuroscience (B.C., Q.C., P.D.L.), University of California–San Diego, La Jolla, Calif; and the Department of Neurology (P.D.L.), Cedars-Sinai Medical Center, Los Angeles, Calif. 3Department of Endocrinology, Guangdong Second Provincial General Hospital, Guangzhou, China Department of Chemistry, Zhejiang Sci-Tech University; Leibniz-Institut für Katalyse e. V. an der Universität Rostock Key Laboratory for Polar Science, Ministry of Natural Resources, Polar Research Institute of China, Shanghai, China Department of Breast Surgery, the First Hospital of China Medical University, Shenyang, Liaoning 110001, China Department of Pathophysiology, Key Lab for Shock and Microcirculation Research of Guangdong Province, Southern Medical University, Guangzhou, People's Republic of China; Department of Hand Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China (mainland) Department of Nuclear Medicine The First Affiliated Hospital of Dalian Medical University Dalian Liaoning People's Republic of China Heilongjiang Feihe Dairy Co., Ltd., Beijing 100015, China Department of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China. Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China (mainland) Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research, Ministry of Education, Hunan Normal University, Changsha 410081, China, and National Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100021, China Department of Gastrointestinal Surgery Center, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China (mainland) School of Chemistry & Chemical Engineering; National Engineering Research Center for colloidal materials; Shandong University; Jinan 250100, P. R. China School of Semiconductor and Physics, North University of China, Taiyuan 030051, China Institute of New Energy for Vehicles School of Materials Science and Engineering Tongji University Shanghai 201804 P. R. China; Key Laboratory of Performance Evolution and Control for Engineering Structures of the Ministry of Education Tongji University Shanghai 200092 P. R. China Department of Human Anatomy, Southwest Medical University, Luzhou, Sichuan, China; Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut; and Department of Radiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China Key Laboratory of Polar Science, MNR, Polar Research Institute of China, Shanghai, 200136, PR China Translational Medicine Centre, Honghui Hospital, Xi’an Jiaotong University, Xi’an, Shannxi, People’s Republic of China Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115;; Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT 06511; Center for Programmable Materials School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore; Department of Chemistry City University of Hong Kong Kowloon Hong Kong China Department of Chemical Engineering and Division of Bioengineering and Environmental Health, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139 Institute of Applied Chemistry College of Chemistry Nanchang University Nanchang 330031 P. R. China School of Ophthalmology and Optometry and Eye hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China; the Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China Laboratory of Xinjiang Endemic and Ethnic Diseases, Medical College, Shihezi University, Shihezi 832002, China. Department of Breast Surgery, The First Hospital of China Medical University, Shenyang, 110001, Liaoning Province, China Associate chief doctor, Department of Oral Implantology Peking University School and Hospital of Stomotology Beijing PR China Department of Plastic and Burn Surgery, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, China Departments of Genetics and Opthalmology and Howard Hughes Medical Institute, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA. State Key Laboratory of Pollution Control and Resource Reuse, College of Environmental Science and Engineering, Tongji University, 1239 Siping Road, Shanghai 200092, P. R. China Center for Programmable Materials School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore; Nanyang Environment and Water Research Institute Interdisciplinary Graduate School Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore Department of Gastrointestinal Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China College of Mathematics and Statistics Shenzhen University Shenzhen 518060 China Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, P. R. China School of Resources and Environmental Engineering, Wuhan University of Technology, Wuhan 430070, People's Republic of China Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China Department of Cardiology, the First People's Hospital of Neijiang, Neijiang, Sichuan Province Research Institute of Orthopedics & Traumatology, Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China Science and Technology Achievement Incubation Center, Kunming, Yunnan 650500, P.R. China Clinical Trial Center, Zhongnan Hospital of Wuhan University, Wuhan, 430071. ##Email#. Key Laboratory of Phytochemistry R&D of Hunan Province, Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research of Ministry of Educational of China Institute of Interdisciplinary Studies, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China Department of Pharmacy Fujian Medical University Union Hospital Fuzhou China; College of Pharmacy Fujian Medical University Fuzhou China Department of Applied Physical Sciences; The University of North Carolina at Chapel Hill; Chapel Hill; USA Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, People’s Republic of China; Dalian National Laboratory for Clean Energy, Dalian 116023, People’s Republic of China; University of the Chinese Academy of Sciences, Beijing 100049, People’s Republic of China Shanghai Key Laboratory for Bone and Joint DiseasesShanghai Institute of Traumatology and OrthopaedicsShanghai Jiaotong University School of Medicine Shanghai China Research Center for Stem Cell Therapies, Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC), Chengdu, China SOA Key Laboratory for Polar Science, Polar Research Institute of China, Shanghai 200136, China Key Laboratory of Luminescence and Optical Information, Ministry of Education, Institute of Optoelectronic Technology, Beijing Jiaotong University, Beijing 100044, People's Republic of China, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, People's Republic of China, and School of Chemistry, University of East Anglia, Norwich, NR4 7TJ, United Kingdom Department of Cardiology, The First People’s Hospital of Neijiang, Neijiang, Sichuan Province, China Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China; West China School of Medicine, Sichuan University, Chengdu 610041, China College of Bioinformatics Science and Technology, Harbin Medical University, Baojian Road, Nangang District, Harbin, 150086, China Department of Pathology, Zhejiang Cancer Hospital, Hangzhou 310022, Zhejiang Province, China Department of Gastrointestinal Surgery, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen Fujian 361003, P.R. China Institute of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China Department of Pathophysiology Key Laboratory for Shock and Microcirculation Research of Guangdong Province Southern Medical University Guangzhou 510515 PR China Department of Breast Oncology Sun Yat‐sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Guangzhou Guangdong China Department of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, New York 14853, United States Department of Oncology, The First People's Hospital of Chengdu City, Chengdu 610041, PR China Department of Oral Implantology Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Disease & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology Beijing PR China Department of Rheumatism and Immunology, West China Hospital of Sichuan University, Chengdu, Sichuan, China. Shanghai Key Laboratory for Bone and Joint DiseasesShanghai Institute of Traumatology and OrthopaedicsShanghai Ruijin HospitalShanghai Jiaotong University School of MedicineShanghaiChina National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC); Collaborative Innovation Center for Cancer Medicine Beijing China 1.Shi's Center of Orthopedics and Traumatology, Shuguang Hospital Affiliated to Shanghai University of TCM, Shanghai 201203, China; 2.Institute of Traumatology & Orthopedics, Shanghai Academy of TCM, Shanghai 201203, China. Clinical Medical College & Affiliated Hospital, Chengdu University, Chengdu, China Institute of Environmental Science, Zhejiang University, Hangzhou 310029, China. chenbo1980119@163.com Laboratory of Chemical Physics and Trauma Medicine Center, Peking University People’s Hospital, Beijing, China; Key Laboratory of Trauma and Neural Regeneration, Ministry of Education, Peking University, Beijing, China; National Center for Trauma Medicine, Beijing, China Key Laboratory of Molecular Biology in High Cancer Incidence Coastal Chaoshan Area of Guangdong Higher Education Institutes, Medical College of Shantou University, Shantou 515041, P. R. China; Institute of Oncologic Pathology, Medical College of Shantou University, Shantou 515041, P. R. China Provincial Key Laboratory of Conservation and Exploitation of Biological Resources in Anhui, College of Life Sciences, Anhui Normal University, Wuhu 241000, China. Department of Hematology, First Affiliated Hospital of Soochow University, Suzhou 215006, China. National Laboratory of Solid State Microstructures, Collaborative Innovation Center of Advanced Microstructures, and School of Physics, Nanjing University, Nanjing 210093, China Department of Osteopathic Oncology, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi 710054, P.R. China School of Science, Hangzhou Dianzi University, Hangzhou, Zhejiang, PR China Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research; Ministry of Education; Key Laboratory of Phytochemical R&D of Hunan Province; College of Chemistry and Chemical Engineering; Hunan Normal University SOA Key Laboratory for Polar Science, Polar Research Institute of China, Shanghai 200136, PR China Department of Endocrinology, The First People’s Hospital of Kerqin District, Tongliao City, Inner Mongolia, China Department of Geriatrics, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Key Laboratory of Phytochemical R&D of Hunan Province, Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research, (Ministry of Education of China), Hunan Normal University, Changsha 410081, China Institute of New Energy for Vehicles, Shanghai Key Laboratory of Development & Application for Metallic Functional Materials, School of Materials Science and Engineering, Tongji University, Shanghai 201804, China; Key Laboratory of Advanced Civil Engineering Materials (Tongji University), Ministry of Education, Shanghai 201804, China School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, China Institute of Oncologic Pathology, The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College Shantou Guangdong China Contribution from the Departments of Chemistry, Computer Science, Mechanical Engineering and Materials Science, and the Smalley Institute for Nanoscale Science and Technology, Rice University, Houston, Texas 77005, and Department of Electrical and Computer Engineering, North Carolina State University, Raleigh, North Carolina 27695 Dalian National Laboratory for Clean Energy, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 116023 Dalian, Liaoning, China Department of Nephrology, The First Affiliated Hospital of Wenzhou Medical University , Wenzhou, Zhejiang, PR China; Institute of Chronic Kidney Disease, Wenzhou Medical University , Wenzhou, Zhejiang, PR China Department of Radiation Oncology, Cancer Hospital (Institute), Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China. Department of Breast Surgery, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research, Ministry of Education Hunan Normal University Changsha P. R. China Department of Plastic Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Science, Peking Union Medical College State Local Joint Engineering Research Center for Functional Materials Processing, School of Metallurgy Engineering Xi'an University of Architecture and Technology Xi'an Shaanxi 710055 P. R. China Materials Science and Devices Institute Suzhou University of Science and Technology Suzhou 215009 China Shenzhen Chipscreen Biosciences Co., Ltd. Shenzhen China State Key Laboratory of Optoelectronic Materials and Technologies, School of Physics, School of Electronics and Information Technology, Sun Yat-sen University, Guangzhou 510275, China Department of Pediatrics, First Affiliated Hospital, Medical College, Shihezi University, Shihezi, Xinjiang 832002, China. 58432141@qq.com. Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; and Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui China Division of Non‐Communicable Disease Control and Community Health Chinese Center for Disease Control and Prevention Beijing China SOA Key Laboratory for Polar Science, Polar Research Institute of China, Shanghai, China Miramar Labs Inc. Santa Clara California 95051 Institute of Microelectronics of Chinese Academy of Sciences Beijing 100029 P. R. China Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou 310018, People’s Republic of China; Leibniz-Institut für Katalyse e. V., Universität Rostock, Albert-Einstein-Straβe 29a, 18059 Rostock, Germany Key Laboratory of Phytochemical R&D of Hunan Province; Hunan Normal University; Changsha 410081, China; Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research; Ministry of Education Center of Implant Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China. MD_CHENBO@sina.com Materials Science and Devices Institute; Suzhou University of Science and Technology; Suzhou 215009; China State Key Laboratory of Nonlinear Mechanics (LNM), Institute of Mechanics, Chinese Academy of Sciences, Beijing, China;; School of Engineering Science, University of Chinese Academy of Sciences, Beijing, China; Shandong University of Science and Technology Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, The First Dongguan Affiliated Hospital, School of Basic Medical Sciences, Guangdong Medical University, Dongguan, China Key Laboratory of Diagnosis and Treatment of Severe Hepato‐Pancreatic Diseases of Zhejiang Province The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang China Department of Hepatobiliary Surgery, Shanghai East Hospital, Tongji University School of Medicine , 150 Jimo Road , Shanghai 200120 , China Spinal and Trauma’s Ward, The 3rd People Hospital of Dalian, Dalian 116000, China Key Laboratory of Phytochemical R&D of Hunan Province; College of Chemistry and Chemical Engineering; Hunan Normal University; Changsha; China Institute for Materials Science and Devices School of Materials Science and Engineering Suzhou University of Science and Technology Kerui Road Suzhou 215009 P.R. China; Jiangsu Key Laboratory for Biomaterials and Devices Department of Biological Science and Medical Engineering Southeast University Nanjing 210009 P. R. China Research Center of Experimental Acupuncture Science, College of Acumox and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China Laboratory of Protein Dynamics and Signaling, Center for Cancer Research, Building 560, Room 22-103, National Cancer Institute, Frederick, MD 21702 Department of Cardiovascular Surgery, West China Hospital Sichuan University Chengdu Sichuan China Department of Breast Cancer, Cancer Center Guangdong Provincial People’s Hospital and Guangdong Academy of Medical Sciences Guangzhou China Department of Plastic and Reconstructive Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing School of Food and Biological Engineering Hefei University of Technology Hefei 230601 China; Engineering Research Center of Bio‐process Ministry of Education Hefei University of Technology Hefei 230601 China Department of Statistical Sciences, University of Toronto, Sidney Smith Hall, 100 St. George Street, Toronto, ON, Canada Department of Thyroid Surgery, Qilu Hospital of Shandong University, Shandong SOA Key Laboratory for Polar Science, Polar Research Institute of China, Shanghai 200136, People’s Republic of China Key Laboratory of Integrated Regulation and Resource Development on Shallow Lake of Ministry of Education, College of Environment, Hohai University, Nanjing, China; College of Environment, Hohai University, Nanjing, China Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China School of Pharmacy, University of Reading, Reading, United Kingdom. National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Department of Chemical & Petroleum Engineering, University of Wyoming, Laramie, WY 82071, USA Department of Breast Cancer, Guangdong Provincial People's Hospital Guangdong Academy of Medical Sciences Guangzhou China School of Science, Hangzhou Dianzi University, Hangzhou, PR China Department of Nephrology, The First Affifiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, PR China; Institute of Chronic Kidney Disease, Wenzhou Medical University, Wenzhou, Zhejiang, PR China Laser Tangshan Key Laboratory of Advanced Testing and Control Technology, School of Electrical Engineering, North China University of Science and Technology, No. 21, Bohai Road, Tangshan 063210, China State Key Laboratory of Pollution Control and Resource Reuse; College of Environmental Science and Engineering; Tongji University; Shanghai 200092, China Department of Materials Science and Engineering, Virginia Tech, Blacksburg, Virginia 24061, United States The Otolaryngology of Shengjing Hospital of China Medical University, Shenyang 110004, China. National Key Laboratory of Public Health and Security, Department of Public Health, Fudan University, Shanghai 200032, China. Department of Ophthalmology, UT Southwestern Medical Center, Dallas, Texas, United States Research Center of Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China Aerospace Information Research Institute Chinese Academy of Sciences Beijing 100190 China Department of Orthopedics, Linyi Second People’s Hospital, Linyi, China; Chinese Academy of Sciences Department of Cardiology, The First Affiliated Hospital with Nanjing Medical University Nanjing 210029, China. Department of Systems Biology, College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China Shanghai Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, 3663 North Zhongshan Lu, Shanghai 200062, P. R. China, and State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, P. R. China Center for Experimental Acupuncturology, Tianjin University of Chinese Medicine, Tianjin 300193, China. tjutcmchenbo@163.com Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, Jilin Province, 130033, China Chemical Synthesis and Pollution Control; Key Laboratory of Sichuan Province; College of Chemistry and Chemical Engineering; China West Normal University; Nanchong 637002 The Department of Plastic and Burn Surgery, Shenzhen Hospital, Southern Medical University, Shenzhen, China; The Third School of Clinical Medicine, Southern Medical University, Shenzhen, China National Laboratory of Solid State Microstructures, Collaborative Innovation Center of Advanced Microstructures, and College of Physics, Nanjing University, Nanjing 210093, China Translational Medicine Centre, Honghui Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, China (mainland) Key Laboratory of Molecular Cell Biology and New Drug Development of the Educational Department of Jinzhou Province, Food Science and Engineer College, Jinzhou Medical University, Jinzhou, Liaoning 121001, P.R. China Department of Chemistry, Indiana University, Bloomington, Indiana 47405, United States Cell Engineering Research Centre and Department of Cell Biology State Key Discipline of Cell Biology, Fourth Military Medical University Xi'an 710032 China Clinical Laboratory Medicine, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China Department of Chemistry and the Center for Advanced, Scientific Computing and Modeling, University of North Texas, 1155 Union Circle, #305070, DentonTexas, 76203-5070, United States College of Chemistry and Molecular Sciences, Key Laboratory of Biomedical Polymers of Ministry of Education, Institute of Molecular Medicine, Renmin Hospital of Wuhan University, School of Microelectronics, Wuhan University, Wuhan 430072, P. R. China Department of Breast Cancer, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China Institute of Materials Science and Devices, School of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou 215011, China Jiangsu Key Laboratory for Biomaterials and Devices; Department of Biological Science and Medical Engineering; Southeast University; Nanjing 210009; P. R. China Department of Physics, University of Central Florida, 4000 Central Florida Boulevard, Orlando, Florida 32816, United States Department of Nutrition and Food Hygiene, School of Public Health Fudan University Shanghai 200032 China Nuclear Medicine Department of Gastrointestinal Surgery, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China (mainland) State Key Laboratory of Microbial Metabolism, School of Life Sciences & Biotechnology Shanghai Jiao Tong University Shanghai 200240 China College of Chemistry and Molecular Sciences; Wuhan University; Wuhan 430072; China Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China; West China School of Medicine, Sichuan University, Chengdu, China School of Architectural Engineering, Quzhou University, Quzhou, Zhejiang 324000, China Department of School of Basic Medicine, College of Medicine, Qingdao University , Qingdao , 266071 , China Department of Breast Cancer, Cancer Center, Guangdong Provincial People's Hospital Guangdong Academy of Medical Sciences Guangzhou China Chengdu NBbiolab Co., Ltd., Chengdu 611130, China Dalian Research Institute of Petroleum and Petrochemicals, SINOPEC, Dalian, 116045, China State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering, Nanjing Hydraulic Research Institute, Nanjing 210029, China Department of Stomatology, Jinling Hospital, Medical School of Nanjing University, Nanjing, China Department of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599, USA. College of Electrical and Electronic engineering, Wenzhou University, Wenzhou 325000, China School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue 639798 Singapore; 3 Environmental Chemistry and Materials Group Nanyang Environment and Water Research Institute Interdisciplinary Graduate School Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore Plastic Surgery Department, China-Japan Friendship Hospital, Beijing, China |
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