http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_acc41dd06fb35984119d88043bbfa1c7
Outgoing Links
Predicate | Object |
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family-name | Rong Wang Wang |
name | Rong Wang Rong. Wang |
given-name | Rong. Rong |
organization-name | Fujian College of Chinese Medicine, Fuzhou, China. State Key Laboratory of Reproductive Medicine, Research Center for Bone and Stem Cells, Department of Anatomy, Histology, and Embryology, Nanjing Medical University, Jiangsu, China; and Institute of Plant Virology Ningbo University Ningbo 315211 China; College of Plant Protection Nanjing Agricultural University Nanjing 210095 China Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China bCancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale University; and; cDepartment of Chronic Disease Epidemiology, and School of Ecological and Environmental Sciences, Tiantong National Station for Forest Ecosystem Research, East China Normal University , Shanghai 200241, China 1 Department of Thyroid and Breast Surgery, West China Hospital, Sichuan University, Chengdu 610041, China ; 2 Department of Breast Surgery, the Affiliated Hospital of Guiyang Medical College, Guiyang 550000, China ; 3 Laboratory of Stem Cell Biology, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China. College of Plant Protection Nanjing Agricultural University Nanjing China; Ministry of Agriculture Key Laboratory of Biotechnology in Plant Protection, Zhejiang Provincial Key laboratory of Plant Protection, Institute of Virology and Biotechnology Zhejiang Academy of Agricultural Sciences Hangzhou China Shanghai Key Laboratory of Crime Scene Evidence Shanghai Institute of Forensic Science Shanghai China Contribution from the Discovery Chemistry Research and Technologies, Biology Research Technologies and Proteins, Lilly Research Labs, Lilly Corporate Center, Eli Lilly & Co., Indianapolis, Indiana 46285, and The Roche Protein Expression Group, Roche Diagnostics Corporation, 9115 Hague Road, Indianapolis, Indiana 46250 Department of Radiology Eye & ENT Hospital of Shanghai Medical School, Fudan University Shanghai 200031 China Department of Anatomy and Cell Biology East Carolina University Brody School of Medicine Greenville NC USA Department of Neurology, Xiangya Hospital, Central South University, Changsha, China. Central Laboratory, Xuanwu Hospital, Capital Medical University, Beijing 100053, China; Beijing Geriatric Medical Research Center, Beijing 100053, China; Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Beijing 100053, China Dept. of History of Sci. and Tech. and Archaeometry of University of Science and Technology of China, Hefei 230026, China. Shanghai Key Laboratory of Crime Scene Evidence, Shanghai Institute of Forensic Science, Shanghai 200083, China Department of Hematology,The First Affiliated Hospital of Nanjing Medical University, Jiangsu Provincial People Hospital, Nanjing 210029,Jiangsu Province,China SupervisingTechnician. E-mail:viviwr@sina.com. Department of Physiology, School of Basic Medical Sciences, Cheeloo Medical College Shandong University Jinan China Institute of Hematology, Medical College of Jinan University, Guangzhou 510632, China. rwang@iarc.fr Department of Radiology, Huashan Hospital Fudan University Shanghai China; Institute of Functional and Molecular Medical Imaging Fudan University Shanghai China Medical college Qinghai University Xining Qinghai Province China Institute of Materials Research, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, P.R. China; State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, P.R. China Department of Anesthesiology, Institute of Anesthesiology and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China Zhejiang Tiantong Forest Ecosystem National Observation and Research Station School of Ecological and Environmental Sciences East China Normal University Shanghai 200241 China; Shanghai Institute of Pollution Control and Ecological Security Shanghai 200092 China Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center at Yale University School of Medicine,; Department of Chronic Disease Epidemiology, School of Public Health, and 2Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut. Department of Nephrology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China; Department of Nephrology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China Department of Human Anatomy, Research Center for Bone and Stem Cells; Key Laboratory for Aging & Disease, The State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China. School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi’an 710119, China Department of General Surgery The First People’s Hospital of Neijiang Neijiang Sichuan China Department of Physiology and Pathophysiology, Shandong University, Cheeloo College of Medicine, Jinan, Shandong, China Northwestern University, USA Yale Cancer Outcomes Public Policy, and Effectiveness Research Center New Haven Connecticut; Department of Chronic Disease Epidemiology Yale School of Public Health New Haven Connecticut School of Information Science and Engineering, East China University of Science and Technology, Shanghai 200237, P. R. China Department of Human Anatomy, Research Centre for Bone and Stem Cells; Key Laboratory for Aging & Disease; The State Key Laboratory of Reproductive Medicine Nanjing Medical University Nanjing Jiangsu China Department of Intensive Care Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, China (mainland) Singapore Membrane Technology Centre, Nanyang Technological University, Singapore State Key Laboratory of Reproductive Medicine, Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Key Laboratory for Aging & Disease Nanjing Medical University Nanjing China Hainan Provincial Key Laboratory of Tropical Maricultural Technologies, Hainan Academy of Ocean and Fisheries Sciences, Haikou 571126, China Department of Cardiovascular Surgery, Institute of Cardiac Surgery of PLA, Beijing 100853, P.R. China Department of Nephrology Shandong Provincial Hospital Jinan Shandong 250021 China Forestry College Fujian Agriculture and Forestry University Fuzhou China; Key Laboratory of Integrated Pest Management in Ecological Forests Fujian Agriculture and Forestry University Fuzhou China The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health and Cancer Outcomes, Public Policy, and Effectiveness Research Center,; Department of Chronic Disease Epidemiology, and CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South Central Experimental Station of Animal Nutrition and Feed Science in the Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtro; College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan, China Department of Pharmacy, 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050. wangrong-69@163.com. School of Pharmacy, Gansu University of Traditional Chinese Medicine, Lanzhou 730000. wangrong-69@163.com. Central Laboratory, Xuanwu Hospital, Capital Medical University, Key Laboratory for Neurodegenerative Disease of the Ministry of Education, Beijing, China; Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Capital Medical University, Beijing, China; Beijing Geriatric Medical Research Center, Beijing, China The Affiliated Nanjing Drum Tower Hospital; State Key Laboratory of Analytical Chemistry for Life Science; and Jiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing, Jiangsu 210008, China Department of Radiology, Eye & ENT Hospital of Shanghai Medical School, Fudan University, Shanghai, China The State Key Laboratory of Reproductive Medicine Department of Anatomy Histology and Embryology Nanjing Medical University Nanjing China Nanjing University 1 Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, Nanjing National Laboratory of Microstructures, , Nanjing 210093, China Department of Population and Data Sciences, Yale University, New Haven, CT, USA Key Laboratory of the Plateau Environmental Damage Control, Lanzhou General Hospital of Lanzhou Military Command, PLA, Lanzhou 730050, China. wangrong-69@163.com. State Key Laboratory of Military Stomatology, Department of Oral Biology, School of Stomatology, The Fourth Military Medical University, Xi’an 710032, China. Departments of Oncology, the First Affiliated Hospital of Soochow University, Suzhou, China University of North Carolina at Chapel Hill Department of Biology , , Chapel Hill, North Carolina 27599, USA School of Computer and Communication Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, China Beijing National Laboratory for Molecular Sciences; Key Laboratory of Polymer Chemistry and Physics of Ministry of Education; College of Chemistry and Molecular Engineering; Peking University; Beijing 100871 P. R. China Department of Chronic Disease Epidemiology Yale University School of Public Health Yale Cancer Outcomes, Public Policy and Effectiveness Research Center New Haven CT College of Life Sciences, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing 210095, People's Republic of China School of Chemistry Beihang University No. 37 Xueyuan Road Haidian District Beijing 100191 China; CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology Beijing 100190 China PLA Key Laboratory of Plateau Environmental Damage Control, Lanzhou General Hospital of Lanzhou Military Command, Lanzhou, 730050, China; School of Pharmacy, Lanzhou University, Lanzhou, 730000, China Muscle Biology Group, Department of Animal Science and Department of Biochemistry and Biophysics, Iowa State University, Ames, Iowa The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei‐MOST) & Key Laboratory of Oral Biomedical Engineering of Ministry of Education, School & Hospital of Stomatology Wuhan University Wuhan P. R. China Center for Systems and Synthetic Biology, Institute of Cellular and Molecular Biology, and Department of Chemistry and Biochemistry, University of Texas at Austin, 2500 Speedway, MBB 3.210 Austin, Texas 78712 Institute of Digestive Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University Key Lab of Separation Science for Analytical Chemistry; Dalian Institute of Chemical Physics; Chinese Academy of Sciences; Dalian 116023; China Gansu University of Chinese Medicine Lanzhou China; Department of Orthopedics the General Hospital of PLA Lanzhou China Central Laboratory, Xuanwu Hospital, Capital Medical University, Beijing Geriatric Medical Research Center, Beijing, China; Beijing Institute for Brain Disorders, Beijing, China bDepartment of Chronic Disease Epidemiology, Yale School of Public Health;; cYale Cancer Outcomes, Public Policy, and Effectiveness Research Center; and Department of Clinical Laboratory, Huangpu Branch, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, P.R. China Zhengzhou Research Base, State Key Laboratory of Cotton Biology, School of Agricultural Sciences, Zhengzhou University, Zhengzhou 450001, China; Henan Key Laboratory of Ion-Beam Bioengineering, School of Agricultural Sciences, Zhengzhou University, Zhengzhou 450052, China Department of Nephrology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China. Department of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia Shenzhen Key Laboratory of Soft Mechanics & Smart Manufacturing, Southern University of Science and Technology, Shenzhen518055, China; Department of Mechanical and Energy Engineering, Southern University of Science and Technology, Shenzhen518055, China From the Research Institute of Atherosclerotic Disease, Health Science Center and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education of China (L.B., Q.L., H.G., S.Z., R.L., R.W., E.L.), Laboratory Animal Center, Health Science Center (L.B., Q.L., H.G., S.Z., R.L., R.W., E.L.), Cardiovascular Research Center, School of Basic Medical Sciences, Health Science Center (L.B., Z.L., J.Z., N.W., J.Y.-J.S.), Xi’an Jiaotong University, Shaanxi, China; Department of Pathology,... Xi’an Key Laboratory for Research and Development of Innovative Multi-Target Antihypertensive Drugs, Xi’an Innovative Antihypertensive Drugs International Science and Technology Cooperation Base, Xi’an Medical University, Xi’an 710021, China; Institute of Drug Research, Xi’an Medical University, Xi’an 710021, China; College of Pharmacy, Xi’an Medical University, Xi’an 710021, China School of Life Sciences, Fuyang Teachers College, Fuyang, People's Republic of China Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut From the Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, China (S.K., X.L., D.Z., R.W., Y.Z., Q.Z., J.-z.Z.); China National Clinical Research Center for Neurological Diseases, Beijing (S.K., X.L., D.Z., R.W., Y.Z., Q.Z., J.-z.Z.); Center of Stroke, Beijing Institute for Brain Disorder, China (S.K., X.L., D.Z., R.W., Y.Z., Q.Z., J.-z.Z.) Pfizer Global Research and Development, Groton, Connecticut, USA Department of Biological, Chemical and Physical Sciences, and ‡Department of Mechanical, Materials, and Aerospace Engineering, Illinois Institute of Technology, Chicago, Illinois 60616, United States College of Polymer Science and Engineering; State Key Laboratory of Polymer Materials Engineering; Sichuan University; Chengdu 610065; China Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, P.R. China; Key Laboratory of Glycoconjugate Research, Ministry of Public Health, Shanghai, P.R. China Department of Obstetrics and Gynecology Affiliated Hospital of Guangdong Medical College Zhanjiang China School of Astronautics, Northwestern Polytechnical University, Shaanxi 710072, China Department of Pediatrics, First Hospital, Beijing University, Beijing 100034, China. Programs in Neuroscience, Washington State University, Pullman, Washington Ningbo Yinzhou Ecological and Environmental Monitoring Station, Ningbo, People’s Republic of China Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100083, China. School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, PR China aG.W. Hooper Foundation and Department of Microbiology and Immunology, University of California at San Francisco, San Francisco, California 94143 Wuxi School of Medicine Jiangnan University Wuxi China; School of Food Science and Technology Jiangnan University Wuxi China State Key Laboratory of Seeding Bioengineering, Ningxia Forestry Institute, Yinchuan, PR China Department of Genetics and Genomic Science, Mount Sinai School of Medicine, New York, New York, United States *Immunity to Pulmonary Pathogens Section, Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840; and Department of Central Laboratory, Xuan Wu Hospital, Capital Medical University, Beijing, P.R. China Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China Yale University School of Medicine New Haven CT USA Department of Central Laboratory, Xuanwu Hospital, Capital Medical University, Beijing 100053, China From the Department of Neurosurgery, Beijing Tiantan Hospital (X.-j.-L., S.W., Y.-l.Z., M.T., D.Z., R.W., Y.C., X.Y., S.K., J.-Z.Z.), and Department of Neurosurgery, Beijing Chao-Yang Hospital (P.G.), Capital Medical University, Beijing, China; and Department of Neurosurgery (M.T.), Institute of Neurological Science, Glasgow, UK. Department of Medical Imaging, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China. rongwang@mail.xjtu.edu.cn School of Civil and Environmental Engineering, Nanyang Technological University, Singapore 639798, Singapore; Singapore Membrane Technology Centre, Nanyang Environment and Water Research Institute, Nanyang Technological University, Singapore 637141, Singapore Shanghai Institute of Forensic Science Shanghai Key Laboratory of Crime Scene Evidence Shanghai P. R. China Department of Cardiovascular Surgery, People's Liberation Army General Hospital, Beijing 100853, China Rockefeller University State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China Department of Nephrology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China Department of Physiology Ningxia Medical College Yinchuan Ningxia China Singapore Membrane Technology Centre; Nanyang Technological University; Singapore 637141; Singapore; School of Civil and Environmental Engineering Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health Department of Anatomy and Cell Biology at the Brody School of Medicine, Greenville NC, USA Cancer Outcomes, Public Policy, and Effectiveness Research Center and; Department of Chronic Disease Epidemiology and School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, People’s Republic of China College of Pharmacy, Anhui University of Chinese Medicine Key Laboratory of Modernized Chinese Medicine in Anhui Province Hefei Anhui China Gansu University of Chinese Medicine, Lanzhou, China; Department of Orthopedics, The General Hospital of PLA, Lanzhou, China Linus Pauling Institute; Oregon State University; Corvallis OR 97331 USA Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland School of Material Science & Engineering, Shaanxi University of Science & Technology, Xi’an, 710021, China Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, Laboratoire de Spectrometrie de Masse Bio-Organique, ECPM, 25 rue Becquerel, 67087 Strasbourg cedex, France, and Department of Human Genetics, Mount Sinai School of Medicine, New York, New York 10029 Optics & Optoelectronics Laboratory, Ocean University of China, Qingdao 266071, China. State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources; School of Chemistry & Pharmacy of Guangxi Normal University; Guilin 541004; P. R. China Department of Radiology, Gansu Provincial Hospital, Lanzhou, Gansu, China (mainland) Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale University, New Haven, CT, USA; Department of Chronic Disease Epidemiology, School of Public Health, Yale University, New Haven, CT, USA 1OBP/DBRR-III, CDER, FDA, Silver Spring, Maryland. College of Horticulture Shenyang Agricultural University Shenyang Liaoning 110866 People's Republic of China; Key Laboratory of Protected Horticulture of Ministry of Education Shenyang Liaoning Province China Department of Geriatric Cardiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, P.R. China Department of Basic Medical Sciences, Key Laboratory for Application of High Altitude Medicine, Qinghai University, Xining, China.; Research Center for Qinghai Healthy Development, Key Laboratory for Application of High Altitude Medicine, Qinghai University, Xining, China. Department of Radiology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China Key Lab of Physics and Technology for Advanced Batteries (Ministry of Education), College of Physics, Jilin University, 2699 Qianjin Street, Changchun 130012, China *Department of Immunology, Nankai University School of Medicine, Nankai University, Tianjin, China; Hunan Province Key Laboratory of Crop Sterile Germplasm Resource Innovation and Application, College of Life Science, Hunan Normal University Department of Medical Oncology, The Affiliated Hospital of Qinghai University, Xining, Qinghai 810001, P.R. China Department of Laboratory Medicine, Affiliated Hospital, Youjiang Medical University for Nationalities, Baise 533000, China. Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China. 1The Pacific Vascular Research Laboratory, Division of Vascular Surgery, Department of Surgery Institute of Medical Research, Northwestern Polytechnical University Xi'an China Roman L. Hruska U.S. Meat Animal Research Center, Agricultural Research Service, U.S. Department of Agriculture, Clay Center, Nebraska. School of Electronic Engineering School of Communications and Information Engineering, Chongqing University of Posts and Telecommunications, Chongqing, China College of Chemistry and Chemical Engineering, Northwest Normal University, Key Laboratory of Bioelectrochemistry and Environmental Analysis of Gansu Province, Lanzhou 730070, China. Department of Physiology and Neurobiology Ningxia Medical University Yinchuan China Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China Key Laboratory of Environment and Female Reproductive Health, West China School of Public Health & West China Fourth Hospital Sichuan University Chengdu China Department of Gastroenterology, Fuzhou General Clinical Medical College of Fujian Medical University, Fuzhou 350025, China; Department of Gastroenterology, 900th Hospital of People’s Liberation Army, Fuzhou 350025, China; Department of Gastroenterology, Oriental Hospital Affiliated to Xiamen University, Fuzhou 350025, China Shandong Provincial Hospital, Shandong University, Jinan, China; Department of Nephrology, Shandong Provincial Hospital affiliated to Shandong First Medical University, Jinan, China Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital Nanjing China 2Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale University, New Haven, CT; 3Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT Shanghai Engineering Research Center of Green Energy Chemical Engineering, College of Chemistry and Materials Science, Shanghai Normal University, 100 Guilin Road, Shanghai 200234, P. R. China Nanjing University 1 Department of Polymer Science and Engineering, Nanjing National Laboratory of Microstructures, School of Chemistry and Chemical Engineering, , Nanjing 210093, People’s Republic of China Pacific Vascular Research Laboratory, Division of Vascular Surgery, Department of Surgery, University of California, San Francisco, CA 94143-0507, USA Beijing Institute of Biotechnology Beijing China Key Laboratory for Thermal Science and Power Engineering of the Ministry of Education, Department of Energy and Power Engineering, Tsinghua University, Beijing 100084, China Laboratoire des Sciences du Climat et de l'Environnement LSCE/IPSL CEA‐CNRS‐UVSQ Université Paris‐Saclay F‐91191 Gif‐sur‐Yvette France; Laboratory for Earth Surface Processes College of Urban and Environmental Sciences Peking University 100871 Beijing China; Sino‐French Institute for Earth System Science College of Urban and Environmental Sciences Peking University 100871 Beijing China State Key Laboratory of Reliability and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin, P.R. China College of Chemistry & Pharmacy Northwest A&F University Yangling Shaanxi 712100 P. R. China Department of Pharmacy, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China Institute of Medicinal Biotechnology Chinese Academy of Medical Sciences Peking Union Medical College Beijing China Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400014, China Department of Nephrology, Shandong Provincial Hospital, Jinan, PR China; Key Lab of Physics and Technology for Advanced Batteries (Ministry of Education), College of Physics, Jilin University, Changchun 130023, China College of Life Science, China West Normal University, Nanchong 637002, China. 0532wangrong@163.com Department of Cardiovascular Surgery, PLA General Hospital, Beijing, China State Key Laboratory of Experimental Hematology Institute of Hematology and Blood Diseases Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Tianjin China Beijing National Laboratory for Molecular Sciences; Key Laboratory of Polymer Chemistry and Physics of Ministry of Education; College of Chemistry and Molecular Engineering; Peking University; Beijing 100871 From the Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University (H.Y., X.L., D.Z., Y.Z., R.W., M.Z., J.Z.); China National Clinical Research Center for Neurological Diseases, Beijing (NCRC-ND) (H.Y., X.L., D.Z., Y.Z., R.W., M.Z., J.Z.); Center of Stroke, Beijing Institute for Brain Disorders (H.Y., X.L., D.Z., Y.Z., R.W., M.Z., J.Z.); Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, China (H.Y., X.L., D.Z., Y.Z., R.W., M.Z., J.Z.). Department of Pharmacology, Xi’an Medical University, Xinwang Road,Weiyang District, Xi’an 710021, China Key Laboratory of Stem Cell Biology of Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences & Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, China.; Shanghai Stem Cell Institute, SJTUSM, Shanghai, China. XiangYa School of Public Health, Central South University, Changsha, Hunan 410001, China; School of Nursing, University of South China, Hengyang, Hunan 421001, China Trauma Center, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China (mainland) Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, Box 1498, New York, New York 10029, United States Department of Biochemistry and Molecular Biology, College of Basic Medicine, Key Laboratory of Medical Biotechnology of Hebei Province, Hebei Medical University, Shijiazhuang, Hebei 050017, China Key Laboratory of High Performance Polymer Material and Technology of MOE Department of Polymer Science and Engineering School of Chemistry and Chemical Engineering Nanjing University 210093 Nanjing P. R. China; State Key Laboratory of Coordination Chemistry Nanjing University 210023 Nanjing P. R. China Laboratory of Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, 100871, China Gansu Provincial Hospital, Lanzhou 730000, P. R. China College of Food Science and Engineering; Northwest A&F University; Yangling 712100; China Department of Hematology, First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China Yale University School of Public Health, New Haven, Connecticut. Department of Chronic Disease Epidemiology, Yale School of Public Health , New Haven, Connecticut , USA Department of Environmental Science and Engineering, Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention Fudan University Shanghai 200438 China; Integrated Research on Disaster Risk International Center of Excellence on Risk Interconnectivity and Governance on Weather/Climate Extremes Impact and Public Health Fudan University Shanghai 200438 China; Department of Atmospheric and Oceanic Sciences Institute of Atmospheric Sciences Fudan University Shanghai 200438 China; Center for Urban Eco‐Planning & Design Fudan University Shanghai 200438 China; Big Data Institute for Carbon Emission and Environmental Pollution Fudan University Shanghai 200438 China Department of Chronic Disease Epidemiology, School of Public Health,; Cancer Outcomes, Public Policy, and Effectiveness Research Center, and Department of Radiation Oncology Nanfang Hospital, Southern Medical University Guangzhou China Department of Neuroelectrophysiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China. 3U.S. Food and Drug Administration, Bethesda, Maryland. Department of Pharmacy, 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730020. wangrong-69@163.com. School of Pharmacy, Lanzhou University, Lanzhou 730020. wangrong-69@163.com. Zhejiang Tiantong Forest Ecosystem National Observation and Research Station Shanghai Key Laboratory for Urban Ecological Processes and Eco‐Restoration School of Ecological and Environmental Sciences East China Normal University Shanghai China; Shanghai Institute of Pollution Control and Ecological Security Shanghai China Department of Pharmacy, Lanzhou General Hospital, Lanzhou Command of PLA, Lanzhou 730050, China. Wangrong-69@163.com Department of Gastroenterology, Shanxi Provincial People’s Hospital (The Fifth Hospital of Shanxi Medical University), Taiyuan, China Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana. Department of Pharmacy, School of Medicine, Women’s Hospital, Zhejiang University, Hangzhou, Zhejiang Province, People’s Republic of China; Key Lab Women’s Reproductive Health, School of Medicine, Women’s Hospital, Zhejiang University, Hangzhou, Zhejiang Province, People’s Republic of China Department of Critical Care Medicine, Union Jiangbei Hospital, Huazhong University of Science and Technology , Wuhan, Hubei Province, China Xiangya School of Public Health, Central South University, Changsha 410078. 3201465@qq.com. School of Nursing, University of South China, Hengyang Hunan 421001. 3201465@qq.com. Department of Hematology, College of Medicine, Jinan University, Guangzhou 510632, China. School of Science Xi'an Polytechnic University Xi'an 710048 P. R. China Annenberg School for Communication & Journalism, University of Southern California Center for Molecular Biology, University of Heidelberg, Im Neuenheimer Feld 282, D-69120 Heidelberg, Germany; Laboratory for Mass Spectrometry, The Rockefeller University, New York, NY 10021; and Department of Pathology, University of Melbourne, Parkville, Victoria 3052, Australia Clinical Proteome Center, Tokyo Medical University, 2-6-1, Nishi-shinjuku Shinjuku-ku, Tokyo 163-0203, Japan, AMR Incorporated, 2-13-18, Nakane Meguro-ku, Tokyo 152-0031, Japan, and Department of Human Genetics, Mount Sinai School of Medicine, 1425 Madison Avenue Box 14−52, New York, New York 10029-6574 Division of Energy and Environment, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, P. R. China Department of Otorhinolaryngology Head and Neck Surgery,Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine. 1Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China. State Key Laboratory of Baiyunobo Rare Earth Resource Researches and Comprehensive Utilization; Baotou Research Institute of Rare Earths; Baotou 014030; China; National Engineering Research Center of Rare Earth Metallurgy and Functional Materials School of Medicine Guangxi University Nanning China Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA. Department of Genetics and Genomic Sciences , New York, NY 10029, USA Department of Dermatology, The First Affiliated Hospital of Soochow University , Suzhou 215006 , China Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale University, New Haven, CT, USA; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA for the TESTING Study Group NMR Analytical Core Facility, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, United States Laboratory Animal Center, School of Medicine, Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029 College of Physics; Jilin University; Changchun 130012; China College of Computer Science, Sichuan Normal University, Chengdu 610101, China; Visual Computing and Virtual Reality Key Laboratory of Sichuan, Sichuan Normal University, Chengdu 610068, China; Education Big Data Collaborative Innovation Center of Sichuan 2011, Chengdu 610101, China Shandong University School of Stomatology, Shandong Provincial Key Laboratory of Oral Biomedicine. Jinan 250000,Shandong Province, China.E-mail:wangrong.36@163.com. School of Life Science and Technology, Beijing Institute of Technology, Haidian District, Beijing 100081, China. Cancer Outcomes, Public Policy and Effectiveness Research (COPPER) Center, Yale University; Department of Chronic Disease Epidemiology, Yale School of Public Health Department of Central Laboratory, Xuanwu Hospital, Capital Medical University, Beijing 100053, China. School of Mechanical Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China Department of Cardiovascular Surgery, Chinese PLA General Hospital, Beijing 100039, P.R. China Department of Pathology, Fujian Children's Hospital, Fuzhou, China. Operation Room,Affiliated Hospital of Guizhou Medical University. Department of Pharmacy, 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050. wangrong-69@163.com. Key Laboratory of Embryo Development and Reproductive Regulation of Anhui Province, College of Biological and Food Engineering, Fuyang Teachers College, Fuyang City, Anhui Province 236037, China. 1Cancer Research Institute, State Key Laboratory for Agro‐Biotechnology and Department of Plant Pathology China Agricultural University Beijing 100193 China Beijing Institute of Biotechnology, Beijing 100071, China Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University;; China National Clinical Research Center for Neurological Diseases; and; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University; State Key Laboratory of Molecular Engineering of Polymers; Department of Macromolecular Science; Fudan University; Shanghai 200433; P. R. China Genetics and Genomic Sciences Program, Mount Sinai School of Medicine, New York, NY 10029 Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases; Center of Stroke, Beijing Institute for Brain Disorders; and Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing; and Department of Neurology, Xiangya Hospital, Central South University, Changsha, China. dlian72@sina.com Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, P.R. China Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou, China National Research Institute for Family Planning, China Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Key Lab of Glycoconjugate Research, Ministry of Public Health, Shanghai, China Cixi Institute of Biomedical Engineering & Polymers and Composites Division, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences; Ningbo; People's Republic of China Department of Oncology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Center for Soft Matter Science and Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China Department of Human Anatomy Research Centre for Bone and Stem Cells Key Laboratory for Aging & Disease The State Key Laboratory of Reproductive Medicine Nanjing Medical University Nanjing Jiangsu 211166 China Food Science and Technology Program, Department of Chemistry, National University of Singapore, Science Drive 4, Singapore 117543 School of Medicine, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China Department of Pharmacy, Shanghai Ninth People's Hospital Shanghai JiaoTong University School of Medicine Shanghai China Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of Education Jilin Normal University Changchun 130103 P. R. China Illinois Institute of Technology, Chicago, Illinois 60616, and Argonne National Laboratory, Argonne, Illinois 60439 Department of Nephrology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China; Department of Nephrology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China Department of Cardiovascular Surgery, Peoples' Liberation Army General Hospital, Institute of Cardiac Surgery of People's Liberation Army, Beijing 100853, China. Laboratory Animal Center, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi 710061, China.; Research Institute of Atherosclerotic Disease, Xi’an Jiaotong University Cardiovascular Research Center, Xi’an, Shaanxi 710061, China. Department of Spinal Surgery, Affiliated Hospital of Gansu University of Chinese Medicine, Gansu 730000, China Laboratory of Alzheimer Research, Department of Neurology and Neuroscience, Cornell University Medical College, New York, NY 10021; Laboratory of Molecular and Cellular Neuroscience and Fisher Center for Research on Alzheimer Disease, and Laboratory for Mass Spectrometry, The Rockefeller University, New York, NY 10021; and Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205 College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning 110866, People’s Republic of China; Key Laboratory of Protected Horticulture of Ministry of Education, Shenyang, Liaoning Province, China State Key Laboratory of Lake Science and Environment, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 210008, China State Key Laboratory of Reproductive MedicineThe Research Center for Bone and Stem Cells, Department of Anatomy, Histology, and EmbryologyNanjing Medical UniversityNanjingPeople's Republic of China Molecular Virology Laboratory, Virginia-Maryland Regional College of Veterinary Medicine and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland College of Management Shenzhen University Shenzhen China Division of Medical Oncology Kanazawa University Cancer Research Institute Kanazawa Japan Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, and Department of Biology, Southern University of Science and Technology, Shenzhen, China 1 Department of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China Department of Nephrology, Provincial Hospital Affiliated to Shandong University, No. 324 Jingwu Road, Jinan, Shandong 250013, China Department of Paediatrics, Wuhan Third Hospital (Tongren Hospital of Wuhan University), Wuhan, Hubei, China. University of Science and Technology of China; State Key Laboratory of Cryptology; University of Hong Kong The Cancer Center of the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China College of Forestry, Fujian Agricultural and Forestry University, Fuzhou, Fujian 350002, China. Department of Radiology, HuaShan Hospital Fudan University Shanghai China; Institute of Functional and Molecular Medical Imaging, Fudan University Shanghai China Chengdu Seventh People's Hospital (Affiliated Cancer Hospital of Chengdu Medical College) Department of Global Ecology, Carnegie Institution for Science, Stanford, California 94305, United States Department of Pharmacy, Shanghai Third People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 201999, China 1Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut. Key Laboratory of Tropical Microbial Resources, Hainan Province, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China School of Educational Science, Hunan Normal University, Changsha, Hunan, China; Cognition and Human Behavior Key Laboratory of Hunan Province, Changsha, Hunan, China State Key Laboratory of Analytical Chemistry for Life Science & Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, Nanjing 210093, China Department of Human Anatomy Nanjing Medical University Nanjing P.R. China; Key Laboratory for Aging & Diseases of Nanjing Medical University Nanjing Medical University Nanjing P.R. China Department of Radiation, Fifth People's Hospital of Qinghai Province, Xi Ning, Qing Hai 810007, China; Radiologic Sciences and Respiratory Therapy Division, School of Health and Rehabilitation Sciences, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA Shanghai Key Laboratory of Crime Scene Evidence; Shanghai Institute of Forensic Science; Shanghai P. R. China College of Medicine, Southwest Jiaotong University, Chengdu 610031, China Laboratory of Bacterial Pathogenesis and Immunology, The Rockefeller University, New York, NY 10021; Laboratory for Mass Spectrometry, The Rockefeller University, 1230 York Avenue, New York, NY 10021; Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston, MA 02118; and Department of Microbiology, University of Maryland, College Park, MD 20742 Department of Spinal Surgery, Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou, Gansu 730000, China Department of Developmental BioEngineering; MIRA Institute for Biomedical Technology and Technical Medicine; University of Twente; 7522NB Enschede; The Netherlands College of Biotechnology and Bioengineering Zhejiang University of Technology Hangzhou China Department of Polymer Science and Engineering; School of Chemistry and Chemical Engineering; Nanjing University; Nanjing 210023; P. R. China Shanghai Key Lab of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University Department of Clinical Lab, Weinan Maternal and Child Health Hospital, Shaanxi, Weinan Province, China. Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University , Haikou , China Dept. of Nuclear Medicine General Hospital of Ningxia Medical Univ. Yinchuan Ningxia 750004 China School of Forestry Fujian Agriculture and Forestry University Fuzhou 350002 People's Republic of China Chengdu Seventh People's Hospital and Chengdu Cancer Hospital Department of Nephrology Shandong Provincial Hospital Affiliated to Shandong First Medical University Jinan China Organ Transplant Center First Affiliated Hospital of Sun Yat‐sen University Guangzhou China Pacific Vascular Research Laboratory, Division of Vascular Surgery, Department of Surgery and Department of Anatomy, University of California, San Francisco, CA 94143; and The Wistar Institute, University of Pennsylvania, Philadelphia, PA 19104 Department of Pharmacy; Shanghai 9th People's Hospital; Shanghai Jiao Tong University School of Medicine; Shanghai; China Shaanxi Key Laboratory of Ischemic Cardiovascular Disease Xi'an Medical University Xi'an Shaanxi China; Department of Pharmacology Xi'an Medical University Xi'an Shaanxi China Nanjing University 1 Key Laboratory of High Performance Polymer Materials and Technology of Ministry of Education, Department of Polymer Science and Engineering, State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing National Laboratory of Microstructures, , Nanjing 210093, China College of Fumiture and Art Design, Central South University of Forestry and Technology, Changsha 410004, China Department of Chemistry and Biochemistry, Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin Austin TX USA Department of Pharmacy, No. 3 People’s Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 201900, China Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, China (P.G., Q.Z., X.Y., X.L., X.D., J.W., R.W., Y.Z., D.Z., J.Z.).; China National Clinical Research Center for Neurological Diseases, Beijing (P.G., Q.Z., X.Y., X.L., X.D., J.W., R.W., Y.Z., D.Z., J.Z.).; Center of Stroke, Beijing Institute for Brain Disorders, China (P.G., Q.Z., X.Y., X.L., X.D., J.W., R.W., Y.Z., D.Z., J.Z.).; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, China (P.G., Q.Z., X.Y., X.L., X.D., J.W., R.W., Y.Z., D.Z., J.Z.).; Beijing Translational Engineering Center for 3D Printer in Clinical Neuroscience, China (P.G., Q.Z., X.Y., X.L., X.D., J.W., R.W., Y.Z., D.Z., J.Z.). Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China School of Chemistry, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100191, P. R. China Department of Mechanical and Energy Engineering, Southern University of Science and Technology, Shenzhen 518055, China Hunan Xingtu Aerospace and Spacecraft Manufacturing Co., Ltd., Zhuzhou 412000, China Department of Thoracic Surgery, Meizhou People’s Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, Meizhou, China Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China, Air Quality Research Division, Science and Technology Branch, Environment Canada, 4905 Dufferin Street, Toronto, Ontario M3H 5T4, Canada Key Laboratory of Medical Insects, Guizhou Medical University, Guiyang, China; School of Basic Medical Science, Guizhou Medical University, Guiyang, China Hainan Provincial Key Laboratory of Tropical Maricultural Technologies, Hainan Academy of Ocean and Fisheries Sciences, Haikou, China School of Pharmacy, Lanzhou University, Lanzhou, Gansu, China School of Civil and Environmental Engineering, Nanyang Technological University, Singapore Department of Pharmacy, 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050. wangrong-69@163.com. School of Pharmacy, Lanzhou University, Lanzhou 730000, China. wangrong-69@163.com. State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Plant Immunity Center, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China State Key Laboratory of Agricultural Microbiology Huazhong Agricultural University Wuhan 430070 China; Center for Bioinformatics College of Life Science and Technology Huazhong Agricultural University Wuhan 430070 China Shanghai Key Laboratory of Crime Scene Evidence Shanghai Institute of Forensic Science Shanghai P. R. China Key Laboratory for Experimental Teratology of Ministry of Education and Department of Immunology Shandong Provincial Key Laboratory of Infection & Immunity Shandong University School of Medicine 44 Wenhua Xi Road Jinan Shandong 250012 China Department of Gastrointestinal Surgery, The Affiliated Hospital of Zunyi Medical College, Zunyi, Guizhou Province Institute of Materials for Electronics and Energy Technology (i‐MEET) Friedrich‐Alexander‐Universität Erlangen‐Nürnberg Martensstrasse 7 91058 Erlangen Germany; Erlangen Graduate School in Advanced Optical Technologies (SAOT) Paul‐Gordan‐Straße 6 91052 Erlangen Germany Center for Anesthesiology, Beijing Anzhen Hospital Capital Medical University Beijing China 2Yale Cancer Outcomes, Public Policy and Effectiveness Research (COPPER) Center, New Haven, CT;; 4Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT Zhejiang Tiantong Forest Ecosystem National Observation and Research Station, Shanghai Key Lab for Urban Ecological Processes and Eco‐Restoration, School of Ecological and Environmental Sciences East China Normal University Shanghai China; Shanghai Engineering Research Center of Sustainable Plant Innovation Shanghai China; Shanghai Institute of Pollution Control and Ecological Security Shanghai China Beijing Key Laboratory for Science and Application of Functional Molecular and Crystalline Materials, Department of Chemistry, University of Science and Technology Beijing, Beijing 100083, China Department of Laboratory Medicine, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi 533000, China. Center for Psychological Sciences, Zhejiang University, Hangzhou 310028, China Jiangsu Key Laboratory for the Research and Utilization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, China Department of Hematology, Nanjing Medical University, Jiangsu Provincial Hospital, Nanjing, Jiangsu Province, China. North University of China U. S. Department of Agriculture, Agricultural Research Service, Roman L. Hruska U.S. Meat Animal Research Center, Clay Center, Nebraska, USA Department of Neurosurgery, Beijing Tiantan Hospital Capital Medical University Beijing China; China National Clinical Research Center for Neurological Diseases Beijing China Central Laboratory, Xuanwu Hospital Capital Medical University, Key Laboratory for Neurodegenerative Disease of Ministry of Education, Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Beijing, China Department of Pharmacy Lanzhou General Hospital of PLA, No. 333 Binghe South Road Lanzhou Gansu 730050 People's Republic of China Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China; and; Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing, China College of Management, Shenzhen University, China The First Affiliated Hospital of Soochow University, Suzhou, China School of Pharmacy, Lanzhou University, Lanzhou 730000, China. wangrong-69@163.com. Navigation Research Center, College of Automation Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 211106, China Department of Hematology, Medical College, Jinan University, Guangzhou 510632, China; Ruian People's Hospitol, Zhejiang Province, China. Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences , Kunming 650223 , China; College of Life Science, University of Chinese Academy of Sciences , Beijing 100049 , China; Kunming College of Life Science, University of Chinese Academy of Sciences , Kunming 650223 , China School of Chemistry Beijing Advanced Innovation Center for Biomedical Engineering Beihang University Beijing 100191 China Research Center for Bone and Stem Cells, Department of Anatomy, Histology, and Embryology, Nanjing Medical University, Nanjing, China Massachusetts General Hospital/Harvard Medical School, Wellman Building, 50 Blossom Street, Boston, MA 02114; Department of Molecular Biology, Merck, Sharp, and Dohme Research Laboratories, Neuroscience Research Centre, Terlings Park, Harlow, Essex CM20 2QR, England; Center for Molecular Biology Heidelberg, University of Heidelberg, Im Neuenheimer Feld 282, D-69120 Heidelberg, Germany; Department of Human Genetics, Mount Sinai School of Medicine, 1425 Madison Avenue, New York, NY 10029; and... Tiantong National Observation Station of Forest Ecosystems, Department of Environmental Sciences East China Normal University Shanghai 200062 China; School of Biology, Faculty of Biological Sciences University of Leeds Leeds LS2 9JT UK Shanghai Key Laboratory of Crime Scene Evidence, Shanghai Institute of Forensic Science, Shanghai, China State Key Laboratory for Conservation and Utilization of Bio-resource and School of Life Sciences, Yunnan University , China; State Key Laboratory of Genetic Resources and Evolution, and Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences , China; College of Life Science, University of Chinese Academy of Sciences , China Singapore Membrane Technology Center, Nanyang Environment and Water Research Institute, Nanyang Technological University, 637141 Singapore Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands Rong Wang, Amy J. Davidoff, and Xiaomei Ma, Yale School of Public Health; Rong Wang, Amer M. Zeidan, Xiao Xu, Amy J. Davidoff, Scott F. Huntington, Cary P. Gross, and Xiaomei Ma, Yale Cancer Outcomes, Public Policy, and Effectiveness Research Center; Amer M. Zeidan, Stephanie Halene, Xiao Xu, Scott F. Huntington, Nikolai A. Podoltsev, Cary P. Gross, and Steven D. Gore, Yale School of Medicine, New Haven, CT Central Laboratory, Xuanwu Hospital, Capital Medical University 45 Changchun Street, Beijing 100053, China. 1Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.; 2Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China. Department of Anatomy, Histology and Embryology The Research Center for Bone and Stem Cells Nanjing Medical University Nanjing China Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital Nanjing 210029, People's Republic of China. Geography and Environment University of Southampton Southampton SO17 1BJ UK; State Key Laboratory of Lake Science and Environment Nanjing Institute of Geography and Limnology Chinese Academy of Sciences Nanjing 210008 China Department of Nephrology Shandong Provincial Hospital Affiliated to Shandong University Jinan China 2Human Genetics State Key Laboratory of Lake Science and Environment Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences Nanjing China Jilin University Key Laboratory of Coherence Light and Atomic and Molecular Spectroscopy, Ministry of Education, College of Physics, , People’s Republic of China Center for Accelerated Medical Innovation, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Boston, MA, USA; Center for Nanomedicine, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Boston, MA, USA University of Hong Kong Shanghai Key Laboratory of Crime Scene Evidence, Shanghai 200437, China Molecular Virology Laboratory, VA-MD College of Veterinary Medicine and Maryland Pathogen Research Institute, University of Maryland, College Park, MD, USA School of Psychology, Beijing Normal University Department of Gastroenterology, Shanxi Provincial People's Hospital, The Fifth Hospital of Shanxi Medical University, Taiyuan, Shanxi, China; State Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai 200062, China. School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, People’s Republic of China College of Chemistry and Chemical Engineering Donghua University Shanghai P. R. China Department of Nephrology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250013, Shandong, China State Key Laboratory of Molecular Engineering of Polymers; Department of Macromolecular Science; Fudan University; Shanghai; P. R. China Department of Radiology, The First Affiliated Hospital of Xi’an Jiaotong University. Xi’an, PR China State Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun 130012, P. R. China Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China Department of Nephrology, Shandong Provincial Hospital Affiliated to Shandong University, 324 Jingwuweiqi Road, Jinan, Shandong 250021, P.R. China Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University;; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease; and Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing 210029, Jiangsu Province, China. Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, P. R. China; State Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun 130012, P. R. China Department of Pathology, Shanghai Pudong New Area Traditional Chinese Medicine Hospital, Shanghai 201203, P.R. China Chengdu Lilai Biotechnology Co., Ltd Chengdu China Department of Epidemiology and Public Health Yale University School of Medicine New Haven Connecticut; Cancer Outcomes Public Policy and Effectiveness Research Center, Yale University New Haven Connecticut School of Ecological and Environmental Sciences, Zhejiang Tiantong Forest Ecosystem National Observation and Research Station, East China Normal University, Dongchuan Road 500, Shanghai 200241, People's Republic of China Department of Biological, Chemical and Physical Sciences, Illinois Institute of Technology, Chicago, Illinois 60616, Department of Microbiology and Immunology, Loyola University Medical Center, Maywood, Illinois 60153, and IIT Research Institute, Chicago, Illinois 60616 Department of Oncology the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital Nanjing China Department of Radiology, The First Affiliated Hospital of Medical College, Xi’an Jiaotong University, Xi’an, Shaanxi, China (mainland) MR Technology, Institute for Biodiagnostics (West), National Research Council, Calgary, Alberta, Canada; Experimental Imaging Center and Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada Department of Pharmacy, Women’s Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; Nanchang University College of Pharmacy, Nanchang 330006, China Laboratories of Molecular Biophysics and Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, NY 10021 Heart Center, Qingdao Fuwai Cardiovascular Hospital, Qingdao 266034, Shandong, People's Republic of China Shenzhen Key Laboratory of Biomimetic Robotics and Intelligent Systems Department of Mechanical and Energy Engineering Southern University of Science and Technology Shenzhen 518055 China; Guangdong Provincial Key Laboratory of Human‐Augmentation and Rehabilitation Robotics in Universities Southern University of Science and Technology Shenzhen 518055 China Department of Otolaryngology, Nanfang Hospital, Southern Medical University, Guangzhou, China. kid.jane27@163.com Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou, China. Department of Cardiothoracic Surgery, St. Vincents Hospital, Sydney, Australia Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases; Center of Stroke, Beijing Institute for Brain Disorders; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease; and Faculty of Earth Science, China University of Geosciences, Wuhan 430074, China. joangemm@yahoo.com.cn Beijing Genomics Institute, Chinese Academy of Sciences, Beijing Airport Industrial Zone B-6, Shunyi, Beijing, China 101318, Peking University School of Oncology, Beijing Cancer Hospital/Institute, 52 Fucheng Road, Haidian District, Beijing, China 100036, Beijing Proteomics Institute, Beijing Airport Industrial Zone B-6, Shunyi, Beijing, China 101318, Peking University People's Hospital, Xi-Wai Street, Western District, Beijing, China 100034, Department of Pathology of General Hospital of PLA, 28 Fuxing... Key Laboratory of Cardiovascular Remodeling and Function Research Qilu Hospital, Shandong University Jinan China 1Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Key Lab of Glycoconjugate Research, Ministry of Public Health, Shanghai, China. Department of General Surgery Department of Biological, Chemical, and Physical Sciences and Department of Mechanical, Materials, and Aerospace Engineering, Illinois Institute of Technology, Chicago, Illinois 60616 Department of Gastroenterology, 900th Hospital of Joint Logistics Support Force , Fuzhou, P. R. China Yale Cancer Outcomes, Public Policy, and Effectiveness Research Center New Haven Connecticut; Department of Chronic Disease Epidemiology Yale School of Public Health New Haven Connecticut Xi'an Jiaotong University 1 State Key Laboratory for Strength and Vibration of Mechanical Structures, School of Aerospace, , Xi'an 710049, China College of Biological Science and Engineering; Fuzhou University; Fuzhou 350116; P. R. China School of Chemistry, Biology, and Material Engineering, Suzhou University of Science and Technology, Suzhou 215009, P.R. China Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai 264003, China; Shandong Laboratory of Advanced Materials and Green Manufacturing (Yantai), Yantai 264000, China; College of Life Sciences, Yantai University, Yantai 264005, China Department of Biological, Chemical and Physical Sciences, Illinois Institute of Technology Steroid Research & Mass Spectrometry Unit, Laboratory for Translational Hormone Analytics in Pediatric Endocrinology, Division of Pediatric Endocrinology & Diabetology, Center of Child and Adolescent Medicine Justus Liebig University Giessen Germany 1Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan. Institute of Functional Nano and Soft Materials (FUNSOM) & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215123, China Department of Biochemistry, Loma Linda University School of Medicine, Loma Linda, California. State Key Joint Laboratory of Environment Simulation and Pollution Control, School of Environment, Tsinghua University, Beijing 100084, China Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of Education Wuhan China; School of Pharmaceutical Sciences Wuhan University Wuhan China Department of Wound Repair, The First Affiliated Hospital of Hainan Medical University, Haikou, China Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale University, New Haven, CT, USA;; Department of Health Policy and Management, School of Public Health, Yale University, New Haven, CT, USA School of Computer and Communication Engineering, Zhengzhou University of Light Industry , No. 136, Science Avenue, 450002, Zhengzhou , China Department of Pediatrics Cangzhou People’s Hospital Cangzhou China School of Medical Laboratory Tianjin Medical University Tianjin China Jilin University **Departments of Anatomy and Surgery and the Pacific Vascular Research Laboratory, University of California, San Francisco, CA 94143; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources; Jiangsu Key Lab of Biomass-Based Green Fuel & Chemicals; College of Chemical Engineering; Nanjing Forestry University; Nanjing 210037 School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China Department of Nephrology, Shandong Provincial Hospital, Shandong University, Jinan, P. R. China; Department of Nephrology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, P. R. China Research Center for Environment and Female Reproductive Health, The Eighth Affiliated Hospital, Sun Yat-sen University , Shenzhen 518033, China Department of Cardiovascular Surgery, Institute of Cardiac Surgery, PLA General Hospital, Institute of Cardiac Surgery, Beijing 100853, China Department of Gynecologic Oncology, University of Groningen, University Medical Centre Groningen, Cancer Research Centre Groningen, Groningen, The Netherlands; Department of Laboratory Medicine, Tianjin Medical University, Tianjin, China College of Pharmacy; Anhui University of Chinese Medicine, Key Laboratory of Modernized Chinese Medicine in Anhui Province; Hefei Anhui China Department of Nursing, The First Affiliated Hospital with Nanjing Medical University, Jiangsu Province Hospital Nanjing 210000, Jiangsu, China. Department of General Surgical Intensive Care Unit, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Provincial People's Hospital, Nanjing 210029,Jiangsu, China. State Key Laboratory of Natural Medicines School of Traditional Chinese Pharmacy China Pharmaceutical University Nanjing P. R. China College of Grain Science and Technology Shenyang Normal University Shenyang China Jiangnan University Medical Center Jiangnan University Wuxi 214002 China; Wuxi School of Medicine Jiangnan University Wuxi 214122 China School of Computer and Communication Engineering and Henan Provincial Key Laboratory of Data Intelligence for Food Safety, Zhengzhou University of Light Industry , No. 136, Science Avenue, Zhengzhou 450002 , China Beijing Genomics Institute, Chinese Academy of Sciences, Beijing Airport Industrial Zone B-6, Shunyi, Beijing 101318, Peking University School of Oncology, Beijing Institute for Cancer Research, 52 Fucheng Road, Haidian District, Beijing 100036, Beijing Proteomics Institute, Beijing Airport Industrial Zone B-6, Shunyi, Beijing 101318, and Department of Pathology, General Hospital of PLA, 28 Fuxing Road, Beijing 100853, China, and Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine... Shanghai Key Lab of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, Shanghai 200092, China State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular Science Fudan University Shanghai 200438 China Department of Radiation Oncology, Edwin L. Steele Laboratory for Tumor Biology, Massachusetts General Hospital, Boston, MA, USA Pharmacy of the 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, Lanzhou, China. Institute of Materials Research, Tsinghua Shenzhen International Graduate School, Shenzhen 518055, P. R. China Department of Gynecology, Cancer Institute, Key Laboratory of Cancer Prevention and Intervention, National Ministry of Education, Provincial Key Laboratory of Molecular Biology in Medical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China MOE Laboratory for Earth Surface Process College of Urban & Environmental Sciences, Peking University Beijing China Bamboo Research Institute, College of Biology and the Environment Nanjing Forestry University 159 Longpan Rd. Nanjing 210037 China School of Information and Cyber Security, People’s Public Security University of China, Beijing 100038, China; Key Laboratory of Security Prevention Technology and Risk Assessment of Ministry of Public Security, Beijing 100038, China Eshelman School of Pharmacy and Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, China Laboratory Animal Center, Xi’an Jiaotong University, Xi’an 710061, China Department of Pharmacy, 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050. wangrong-69@163.com. Gansu Plateau Pharmaceutical Technology Center, Lanzhou 730050, China. wangrong-69@163.com. Gansu Plateau Pharmaceutical Technology Center, Lanzhou 730050, China. wangrong-69@163.com. Department of Cardiology Second Affiliated Hospital of Xi'an Jiaotong University Xi'an City China Yale Cancer Outcomes, Public Policy, and Effectiveness Research Center, New Haven, CT; and; Department of Chronic Disease Epidemiology and College of Life Science, Yantai University, YanTai, ShanDong, 264003, P. R. China Affiliated Hospital of Youjiang Medical University for Nationalities, China Department of Physics, University of Hong Kong, Pokfulam, Hong Kong College of Agriculture, Yangtze University, Jingzhou 434025, China Department of Radiology, Eye & ENT Hospital of Shanghai Medical School, Fudan University, Shanghai, PR China Central Laboratory, Xuanwu Hospital, Capital Medical University, Key Laboratory for Neurodegenerative Disease of Ministry of Education, Beijing Geriatric Medical Research Center, No. 45 Changchun Street, Xicheng District, Beijing 100053, China; Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China State Key Laboratory of Natural Medicines, Department of TCMs Pharmaceuticals, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, People’s Republic of China Anhui Province Key Laboratory of Embryo Development and Reproductive Regulation, Anhui Province Key Laboratory of Environmental Hormone and Reproduction, Institute of Life and Food Engineering, Fuyang Normal University, Fuyang, Anhui, China Department of Hematology First Affiliated Hospital Zhejiang University School of Medicine Hangzhou Zhejiang China; Zhejiang Provincial Key Laboratory of Hematopoietic Malignancy Zhejiang University Hangzhou Zhejiang China College of Life Sciences, Capital Normal University, Beijing 100048, China. necawr@126.com State Key Laboratory of Natural Medicines, Department of TCM Pharmaceuticals, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, People’s Republic of China 1Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China. Changchun University of Science and Technology, Changchun 130022, China Department of Pharmacy, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, P.R. China Department of Anatomy, Nanjing Medical University , Nanjing , People’s Republic of China Central Laboratory, Xuanwu Hospital, Capital Medical University, Beijing Geriatric Medical Research Center, Key Laboratory for Neurodegenerative Disease of Ministry of Education, Beijing, China; Beijing Institute for Brain Disorders, Beijing, China School of Stomatology, Guizhou Medical University, Guiyang 550004, China; Dept. of Stomatology, Mianyang Central Hospital, Mianyang 621000, China. Key Laboratory of Environment and Female Reproductive Health, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China Department of Pharmaceutical Engineering, School of Engineering, China Pharmaceutical University, Nanjing 210009, P. R. China College of Horticulture, Hunan Agricultural University, Nongda Road No. 1, Furong District, Changsha410128, Hunan, China Department of Pharmacy, The 940th Hospital of Joint Logistics Support Force of Chinese People’s Liberation Army, Lanzhou, China; College of Pharmacy, Lanzhou University, Lanzhou, China Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China Central Laboratory, Xuanwu Hospital, Capital Medical University, Beijing, China; Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Beijing, China USDA ARS U.S. Meat Animal Research Center, Clay Center, Nebraska, USA Yangqu People's Hospital Taiyuan China NMPA Key Laboratory for Technology Research and Evaluation of Drug Products and Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China Graduate School, Gansu University of Chinese Medicine, Lanzhou 730000, China. Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; and Beijing Key Laboratory of DNA Damage Response and College of Life Sciences, Capital Normal University, Beijing, China Nursing Department, East Campus of Renming Hospital of Wuhan University, Wuhan, China. Pfizer Inc Groton CT USA Key Laboratory for Feed Biotechnology of the Ministry of Agriculture, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing, People's Republic of China; College of Life Sciences, Shanxi University, Taiyuan, People's Republic of China Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale University, New Haven, CT; Department of Chronic Disease Epidemiology Department of Laboratory Medicine The Affiliated Hospital of Youjiang Medical University for Nationalities Baise China Department of Neurosurgery, Capital Medical University affiliated Beijing Tian Tan Hospital, Capital Medical University, Beijing, China National Evaluation Centre for the Toxicology of Fertility Regulating Drug, Department of Pharmacology and Toxicology, Shanghai Institute of Planned Parenthood Research, Shanghai 200032, China Department of Echocardiography, Fuwai Hospital/ National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Laboratory of Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China Biosciences Division, Argonne National Laboratory, Argonne, Illinois 60439 (J.T.B., F.Y., L.C.); and Department of Biological, Chemical, and Physical Sciences, Illinois Institute of Technology, Chicago, Illinois 60616 (D.Q., F.Y., R.W.) Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu Province, China; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu Province, China Xi’an Key Laboratory of Multi Synergistic Antihypertensive Innovative Drug Development, Xi’an Medical University, Xi’an 710021, China; Institute of Drug Research, Xi’an Medical University, Xi’an 710021, China; College of Pharmacy, Xi’an Medical University, Xi’an 710021, China Laboratory of Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, The National Institutes of Health, Bethesda, Maryland 20892 State Key Laboratory of Tribology, Tsinghua University, Beijing 100084, China Department of Biological, Chemical, and Physical Sciences, Illinois Institute of Technology, Chicago, IL 60616, USA Department of Medical Laboratory Animal Science School of Basic Medical Sciences Xi’an Jiaotong University Health Science Center Xi’an China; Research Institute of Atherosclerotic Disease Xi’an Jiaotong University Cardiovascular Research Center Xi’an China College of Horticulture and Plant Protection, Yangzhou University, Yangzhou, China Radiology The First Affiliated Hospital of Fujian Medical University, Fuzhou, PR China; Department of Otolaryngology-Head and Neck Surgery, the Sixth Medical Center of PLA General Hospital, Beijing, PR China; National Key Laboratory of Hearing and Balance Science, Beijing, PR China; National Clinical Research Center for Otolaryngologic Diseases, Beijing, PR China; Beijing Key Lab of Hearing Impairment Prevention and Treatment, Beijing, PR China Department of Cardiovascular Surgery The First Medical Center of PLA General Hospital Beijing China Key Laboratory of Flexible Electronics & Institute of Advanced Materials, Jiangsu National Synergetic Innovation Center for Advanced Materials, Nanjing Tech University, 30 South Puzhu Road, Nanjing 211816, China Public Health Laboratory Sciences and Toxicology, West China School of Public Health, Sichuan University, No. 17 People’s South Road, Chengdu 610041, China School of Laboratory Medicine, Tianjin Medical University, No. 1 Guangdong Road, Hexi District, Tianjin 300203, China BGI‐Shenzhen China; Icahn Institute and Department of Genetics and Genomic Sciences Icahn School of Medicine at Mount Sinai New York NY USA Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China Department of Chronic Disease Epidemiology, School of Public Health, Yale University, New Haven, CT Department of Nutrition, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China Beijing National Laboratory for Molecular Science; Key Laboratory of Polymer Chemistry and Physics of Minister of Education; Center for Soft Matter Science and Engineering; College of Chemistry and Molecular Engineering; Peking University Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Academy for Advanced Interdisciplinary Studies and Department of Biology, Southern University of Science and Technology, Shenzhen, China 1 ZJU Hangzhou Global Sci & Technol Innovat Ctr, Adv Semicond Res Inst, Hangzhou 311215, P. R. China Department of Pharmacology Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China; Department of Pharmacy the Second Affiliated Hospital of Xi'an Medical University Xi'an Shaanxi China Department of Radiology, Eye & ENT Hospital of Fudan University, Shanghai Medical School Fudan University Shanghai China; Department of Radiology, Huashan Hospital of Fudan University, Shanghai Medical School Fudan University Shanghai China Laboratory of Protein Engineering Beijing Institute of Biotechnology Beijing China Department of Nephrology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China National Center for Gene Research, Shanghai Institutes for Biological Sciences, the Chinese Academy of Sciences, Shanghai 200233, China. Department of Ophthalmology, The Affiliated Traditional Chinese Medicine Hospital of Guangzhou Medical University, Guangzhou, China School of Metallurgy and Materials Engineering, Chongqing University of Science & Technology, Chongqing 401331, P. R. China Medical College, Guangxi University Nanning, Guangxi, P.R. China. Department of Human Anatomy, Research Centre for Bone and Stem Cells, Key Laboratory for Aging & Disease The State Key Laboratory of Reproductive Medicine, Nanjing Medical University Nanjing China Department of Pharmacy, School of Stomatology Fourth Military Medical University Xi'an P. R. China Gannan Medical University, Ganzhou, Jiangxi 341000, China Biomedical Polymer Research Group Cixi Institute of Biomedical Engineering Ningbo Institute of Materials Technology & Engineering Chinese Academy of Sciences No. 99 Xuelin Road, Cixi Ningbo 315000 China Key Laboratory of High Performance Polymer Materials and Technology of Ministry of Education; Department of Polymer Science and Engineering; State Key Laboratory of Coordination Chemistry; School of Chemistry and Chemical Engineering; Nanjing National Laboratory of Microstructures Central Laboratory, Xuanwu Hospital, Capital Medical University, Beijing, China; Beijing Geriatric Medical Research Center, Beijing, China; Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Beijing, China College of Forestry Fujian Agriculture and Forestry University Fuzhou China; Key Laboratory of Integrated Pest Management in Ecological Forests Fujian Province University, Fujian Agriculture and Forestry University Fuzhou China Department of Chronic Diseases Epidemiology School of Public Health, Yale University New Haven CT State Key Laboratory of Analytical Chemistry for Life Science & Jiangsu Key Laboratory of Molecular Medicine, Medical School Nanjing University Nanjing China Laboratoire des Sciences de l’Environnement et du Climat, Commissariat à l’Energie Atomique et aux Energies Alternatives/CNRS/Université de Versailles Saint-Quentin-en-Yvelines, 91198 Gif-sur-Yvette, France; Key Laboratory of Horticultural Plant Biology (Ministry of Education), College of Horticulture and Forestry Sciences, Huazhong Agricultural University, Wuhan 430070, China MR Technology, Institute for Biodiagnostics (West), Calgary, Alberta, Canada; Department of Neuroscience, University of Calgary, Calgary, Alberta, Canada Department of Pharmacy, 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050. wangrong-69@163.com. School of Pharmacy, Lanzhou University, Lanzhou 730000. wangrong-69@163.com. Gansu Plateau Pharmaceutical Technology Center, Lanzhou 730050, China. wangrong-69@163.com. Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale University, New Haven, CT, USA;; Department of Chronic Disease Epidemiology, School of Public Health, Yale University, New Haven, CT, USA; Shanghai Engineering Research Center of Green Energy Chemical Engineering, Key Laboratory of Resource Chemistry of Ministry of Education, College of Chemistry and Materials Science, Shanghai Normal University, 100 Guilin Rd., Shanghai 200234, PR China Department of Nephrology, Shandong Provincial Hospital affiliated to Shandong First Medical University , Jinan, Shandong , China; Department of Nephrology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University , Jinan, Shandong , China Key Lab of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China; University of Chinese Academy of Sciences, Beijing 100049, China Laboratory for Mass Spectometry, The Rockefeller University Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China Department of Nephrology, Shandong Provincial Hospital, Shandong First Medical University, Jinan, China Linus Pauling Institute Oregon State University Corvallis OR USA Department of Urology, Jintan People's Hospital Affiliated to Jiangsu University, Jintan, Jiangsu 213200, China. Nursing Department of East campus Renming Hospital of Wuhan University Wuhan China Department of Environmental Science and Engineering, Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention, Institute of Atmospheric Sciences, Fudan University, Shanghai 200433, China Central Laboratory, Xuan Wu Hospital, Capital Medical University, Beijing Geriatric Medical Research Center, Key Laboratory for Neurodegenerative Disease of Ministry of Education, Beijing, China; Beijing Institute for Brain Disorders, Beijing, China Institute of Materials for Electronics and Energy Technology (i-MEET) Friedrich-Alexander-Universität Erlangen-Nürnberg Martensstrasse 7 91058 Erlangen Germany; Erlangen Graduate School in Advanced Optical Technologies (SAOT) Paul-Gordan-Straße 6 91052 Erlangen Germany Department of Clinical Nutrition, Children's Hospital of Nanjing Medical University, Nanjing, China Qinghai University 1Department of Neurosurgery, Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.; 3Modern Medical Research Center, Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China. Xi’an Jiaotong University, China Key Lab of Plant Stress Research, College of Life Sciences, Shandong Normal University, Ji’nan, PR China Department of Wound Repair, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570100, P.R. China Department of Pharmacy School of Stomatology Fourth Military Medical University Xi'an P. R. China Office of Bioequivalence (OB), OGD, CDER, US FDA, Silver Spring, MD 20993, USA. State Key Laboratory of the Seedling Bioengineering , Yinchuan, 750004 , China Department of Radiology, Huashan Hospital of Fudan University, Fudan University, Shanghai 200040, China School of Biology and Food Engineering, Fuyang Normal University, Fuyang 236037, China Department of Polymer Science and Engineering, State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing National Laboratory of Microstructures, Nanjing University, Nanjing 210093, China College of Geomatics, Xi’an University of Science and Technology, Xi’an 710054, China Institute of Cardiovascular Science School of Basic Medical Sciences Xi'an Jiaotong University Health Science Center Xi'an China Laboratory of Respiratory Disease, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi 541001, P.R. China State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biomedical Sciences, Hunan University, Changsha 410082, China State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, People's Republic of China. Department of Endocrinology and Metabolism the Affiliated Hospital of Qingdao University, Qingdao, China and Shandong Provincial Clinical Research Center for Immune Diseases and Gout Qingdao China Center for Optical Imagery Analysis and Learning, Northwestern Polytechnical University, Xi'an 710072, China Laboratory for Lipid Metabolism and Atherosclerosis, Xi’an Jiaotong University Cardiovascular Research Center, Xi’an, Shaanxi 710061, China Key Laboratory of Plant Cell Engineering and Germplasm Innovation, Ministry of Education, College of Life Science, Shandong University, Jinan 250100, People's Republic of China Yale Cancer Outcomes, Public Policy, and Effectiveness Research Center, New Haven, Connecticut; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut Department of Anatomy, Histology and Embryology, State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells Nanjing Medical University Nanjing China Cancer Institute, A Key Laboratory For Cancer Prevention & Intervention, Ministry of Education of the People's Republic of China, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China, and School of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, Georgia, 30332 Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China; Key Laboratory of Hematology, Nanjing Medical University, Nanjing, China; Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China Compound K suppresses myeloid-derived suppressor cells in a mouse model bearing CT26 colorectal cancer xenograft.E-mail: 1135014577@qq.com. National Research Institute for Health and Family Planning, Beijing, China. Key Laboratory of Tropical Biological Resources of Ministry of Education, Department of Pharmacy, College of Marine Science, Hainan University, Haikou, Hainan, China (mainland) State Key Laboratory of Photocatalysis on Energy and Environment College of Chemistry Fuzhou University 350116 Fuzhou P. R. China Chinese Academy of Medical Sciences & Peking Union Medical College Institute of Medicinal Plant Development, 198148, Haidian District, Beijing, China; Departments of Pediatrics, Genetics and Genomics Science, and Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York City, New York 10029, and Department of Chemistry, Michigan State University, East Lansing, Michigan 48824 Molecular Virology Laboratory, VA-MD College of Veterinary Medicine and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA Department of Biological, Chemical, and Physical Sciences, Illinois Institute of Technology, Chicago, Illinois 60616 College of Polymer Science and Engineering State Key Laboratory of Polymer Materials Engineering Sichuan University Chengdu 610065 China Department of Breast Surgery, Yueyang Hospital of Integrated Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China College of Urban and Environmental Sciences, Peking University, Beijing 100871, China U.S. Department of Agriculture, Agricultural Research Service, U.S. Meat Animal Research Center, Clay Center, Nebraska. Research Institute of Pesticidal Design & Synthesis, College of Sciences, Northwest A&F University, Yangling, Shaanxi 712100, People’s Republic of China Department of Neurology Zhongshan Hospital Xiamen University Xiamen China Central Laboratory, Xuan Wu Hospital, Capital Medical University, Beijing, China; Beijing Geriatric Medical Research Center, Beijing, China; Beijing Institute for Brain Disorders, Beijing, China School of Minerals Processing and Bioengineering, Central South University, Changsha, Hunan 410083, People’s Republic of China Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center Yale University New Haven CT USA; Department of Chronic Disease Epidemiology School of Public Health Yale University New Haven CT USA Department of Cardiac Surgery Beijing Anzhen Hospital, Capital Medical University Beijing China Key Laboratory for Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences , Changsha, Hunan, China Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University;; Department of Neurosurgery, Peking University International Hospital, Peking University;; China National Clinical Research Center for Neurological Diseases;; Stroke Center, Beijing Institute for Brain Disorders; State Key Laboratory of Analytacal Chemistry for Life Science and Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, Nanjing 210093, China Authors' Affiliations: Departments of 1Urology and 2Pathogen Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; 3Cancer Biology Program, Hematology-Oncology Division, Department of Medicine, Beth Israel Deaconess Medical Center; 4Department of Urology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; and 5Department of Neurology, Institute of Molecular Medicine and Genetics, Medical College of Georgia, Georgia Regents University, Augusta, Georgia Jiangsu Key Laboratory of Pediatrics, Nanjing, China Department of Human Genetics, Mount Sinai School of Medicine Laboratory of Molecular and Cellular Neuroscience and Fisher Center for Research on Alzheimer's Disease, and Laboratory of Mass Spectrometry, The Rockefeller University, 1230 York Avenue, New York, NY 10021; and Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY 10021 Department of Radiology HuaShan Hospital, Fudan University Shanghai China; Shanghai Institution of Medical Imaging Shanghai China; Institute of Functional and Molecular Medical Imaging Fudan University Shanghai China Department of Chemical and Biomolecular Engineering, National University of Singapore, Kent Ridge, Singapore 117576 Coherent Light and Atomic and Molecular Spectroscopy Laboratory; Key Laboratory of Physics and Technology for Advanced Batteries; College of Physics; Jilin University; Changchun 130012 Shanghai Key Laboratory of Crime Scene Evidence Shanghai Research Institute of Criminal Science and Technology Shanghai China College of Biology and the Environment, Bamboo Research Institute, Nanjing Forestry University, Nanjing, China Department of Nephrology, Shandong Provincial Hospital Affiliated to Shandong University Jinan 250021, P. R. China. Institute of Computational Linguistics, University of Stuttgart , Stuttgart , Germany; School of Foreign Languages, Hangzhou Dianzi University , Hangzhou , China The Second Department of Respiratory, Shanxi Provincial Cancer Hospital, Taiyuan 030000, China. Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Changle Road No. 68, Nanjing, Jiangsu 210029, China The Cancer Center, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong, China Department of Nephrology The First Affiliated Hospital, Sun Yat‐sen University Guangzhou 510080 China; NHC Key Laboratory of Clinical Nephrology (Sun Yat‐Sen University) and Guangdong Provincial Key Laboratory of Nephrology Guangzhou 510080 China Key Laboratory of Environment and Female Reproductive Health, West China School of Public Health, Sichuan University, Chengdu, China. Department of Radiotherapy; Gansu Provincial Hospital; Lanzhou; China School of Civil and Environmental Engineering, Nanyang Technological University, 639798 Singapore; Singapore Membrane Technology Centre, Nanyang Environment and Water Research Institute, Nanyang Technological University, 637141 Singapore Molecular Biology Department, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York 10314, CSI/IBR Center for Developmental Neuroscience and Graduate Program in Biology, City University of New York, New York, New York 10016, Department of Human Genetics, Mount Sinai School of Medicine, New York, New York 10029, and Laboratory for Mass Spectrometry and Gaseous Chemistry, The Rockefeller University, New York, New York 10021 Shandong Provincial Key Laboratory of Plant Stress Research, College of Life Sciences, Shandong Normal University, Ji’nan, Shandong, China State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China Laboratory of Gene Therapy, Department of Biochemistry College of Life Sciences, Shaanxi Normal University Xi'an Shaanxi China Department of Urology, Jintan People's Hospital / The Affiliated Hospital of Jiangsu University, Jintan, Jiangsu 213200, China. Laboratoire des Sciences du Climat et de l’Environnement, CEA CNRS UVSQ, 91191 Gif-sur-Yvette, France Department of Radiation Oncology, Nanfang Hospital Southern Medical University Guangzhou China Department of Critical Medicine, Union Jiangbei Hospital, Huazhong University of Science and Technology, Wuhan, Hubei 430100, P.R. China Yale University School of Medicine, New Haven, CT College of Food Science and Engineering, Northwest A&F University, Yangling, 712100 Shaanxi, P. R. China CAS Key Laboratory for Agro‐Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences Changsha China Department of Oncology, The first affiliated Hospital of Nanjing Medical University Nanjing 210029, China. Department of Clinical Laboratory, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, Guangxi, China 4Yale School of Public Health, Yale University, New Haven, Connecticut. Research Center for Environment and Female Reproductive Health, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China; Department of Toxicology, School of Public Health, Fujian Medical University, Fuzhou, China School of Pharmacy, Lanzhou University, Lanzhou, China;; Key Laboratory of the Plateau Medicial, The 940 Hospital of Joint Logistics Support, PLA, Lanzhou, China Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, People’s Republic of China Department of Nephrology, Shandong Provincial Hospital, Shandong University, Shandong 250021, China. Department of Cardiovascular Surgery, The Sixth Medical Centre Chinese PLA General Hospital Beijing China Department of Urology, Jintan People's Hospital Affiliated to Jiangsu University, Jintan, Jiangsu 213200, China. wrhdham@126.com Derald H. Ruttenberg Cancer Center and Department of Human Genetics, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029-6574 Hubei Key Laboratory of Waterlogging Disaster and Agriculture Use of Wetland and Hubei Collaborative Innovation Centre for Grain Industry and Engineering Research Center of Ecology and Agriculture Use of Wetland, Ministry of Education, Yangtze University, Jingzhou, Hubei 434025, China Department of Chronic Disease Epidemiology Yale School of Public Health New Haven Connecticut; Cancer Outcomes, Public Policy and Effectiveness Research Center Yale University New Haven Connecticut The Affiliated Chinese Medicine Hospital of Xinjiang Medical University, Wulumuqi 830000, Xinjiang, China. Blood Diseases Institute Affiliated Hospital of Xuzhou Medical University Xuzhou Medical University Xuzhou Jiangsu China Department of Central Laboratory, Xuan Wu Hospital, Capital Medical University, Beijing, China. Key Laboratory for Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, China Molecular Virology Laboratory, VA-MD Regional College of Veterinary Medicine and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA Department of Digestive Endoscopy, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, China (mainland) College of Food Science and Engineering; Northwest A&F University; Yangling; P. R. China Key Laboratory of the Plateau Environmental Damage Control, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou, China Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China Laboratory Animal Center, Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China Plastic Surgery Institute of Weifang Medical University Weifang China State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, People’s Republic of China Department of Neurosurgery, Peking University International Hospital;; Departments of Neurosurgery and; China National Clinical Research Center for Neurological Diseases; State Key Joint Laboratory of Environmental Simulation and Pollution Control; School of Environment; Tsinghua University; Beijing 100084; P. R. China Department of Laboratory Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China Department of Chronic Disease Epidemiology, Yale School of Public Health , New Haven, CT , USA Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou 310003, China 2USDA-ARS-US Meat Animal Research Center, Clay Center, NE 68933, USA College of Pharmaceutical Science Soochow University Suzhou China; College of Pharmacy Jiangxi University of Chinese Traditional Medicine Nanchang China NMR Analytical Core Facility, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States School of National Defense Science and Technology, Southwest University of Science and Technology, Mianyang, P.R. China Surgery Department of Nan-lou, Chinese PLA General Hospital, Beijing 100853, China. Department of Polymer Science and Engineering, State Key Laboratory of Coordination Chemistry, Nanjing National Laboratory of Microstructures, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China From Institute of Toxicology, College of Preventive Medicine, The Third Military Medical University, Chongqing, PR China 1Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale University, New Haven, CT; 2Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT School of Chemistry & Materials Science, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, P. R. China Department of Hematology The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital Nanjing China; Key Laboratory of Hematology of Nanjing Medical University Nanjing China; Collaborative Innovation Center for Cancer Personalized Medicine Nanjing China Linus Pauling Institute Oregon State University Corvallis Oregon Nanjing Vocational University of Industry Technology, Nanjing210023, China Department of Gastrointestinal Surgery The Affiliated Hospital of Zunyi Medical University Zunyi Guizhou China Modern Medical Research Center, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, People's Republic of China, and Institute of Physics and Research Center for Applied Sciences, Academia Sinica, Taipei, 11529 Taiwan Food Science and Technology Programme, Department of Chemistry, National University of Singapore, Science Drive 4, Singapore 117543 Rockefeller University, New York, NY 10021. Digestive Endoscopy Center, Shanxi Provincial people’s Hospital, Taiyuan, China Hainan Academy of Ocean and Fisheries Sciences , Haikou 570206, China Fuzhou General Clinical Medical College of Fujian Medical University; Department of Gastroenterology, 900th Hospital of People's Liberation Army Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases; and Central Laboratory Xuanwu Hospital Capital Medical University Key Laboratory for Neurodegenerative Disease of Ministry of Education Center of Alzheimer's Disease Beijing Institute for Brain Disorders Beijing China Hexi University Affiliated Zhangye People’s Hospital , Zhangye, Gansu, China Department of Polymer Science & Engineering, Key Laboratory of High Performance Polymer Material and Technology of Ministry of Education, School of Chemistry & Chemical Engineering, Nanjing University, Nanjing 210023, P. R. China Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Provincial People Hospital, Nanjing 210029, Jiangsu Province, China,E-mail: viviwr@sina.com. Department of Rehabilitation Medicine, Anningshi First People’s Hospital, 2 Henan Road, 650302 Anning, Yunnan, China Huazhong Agricultural University National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, College of Horticulture and Forestry Sciences, , Wuhan, 430070, China School of Pharmacy, Lanzhou University, Lanzhou, 730000, Gansu, China Zhejiang International Scientific and Technological Cooperative Base of Biomedical Materials and Technology, Institute of Biomedical Engineering, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China; Ningbo Cixi Institute of Biomedical Engineering, Ningbo 315300, China Shanghai Key Laboratory of Chemical Biology; School of Pharmacy; East China University of Science and Technology; Shanghai 200237; China State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy China Pharmaceutical University Nanjing People's Republic of China School of Chinese Materia Medica and Yunnan Key Laboratory of Southern Medicinal Utilization Yunnan University of Chinese Medicine Kunming China Beijing Graphene Institute (BGI) Beijing 100095 China Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT; Yale Cancer Outcomes, Public Policy, and Effectiveness Research Center, New Haven, CT Department of Human Genetics, Mount Sinai School of Medicine, New York, New York Department of Nephrology, Provincial Hospital affiliated to Shandong First Medical University, Jinan, PR China Beijing Graphene Institute (BGI), Beijing 100095, China The Rockefeller UniversityLaboratory for Mass SpectrometryNew York Department of Nephrology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China U.S. Department of Agriculture, Agricultural Research Service, Roman L. Hruska U.S. Meat Animal Research Center, Clay Center, Nebraska, USA Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China. School of Pharmacy, Lanzhou University, Lanzhou, China;; Key Laboratory for Prevention and Remediation of Plateau Environmental Damage, Lanzhou General Hospital, Lanzhou, China The First Affiliated Hospital The Second Affiliated Hospital Institute of Translational Medicine School of Public Health State Key Laboratory of Experimental Hematology Zhejiang University School of Medicine 310058 Hangzhou China Department of Laboratory Medicine, Tianjin Medical University, Tianjin 300060, China PLA Key Laboratory of the Plateau of the Environmental Damage Control, Department of Pharmacy Lanzhou General Hospital of PLA Lanzhou 730050 China; School of Pharmacy Lanzhou University Lanzhou 730000 China Department of Urology, The Jintan Hospital Affiliated with Jiangsu University, Changzhou, Jiangsu, P.R. China Department of Gastroenterology, 900TH Hospital of Joint Logistics Support Force, Fuzhou, China Department of Hematology, First Affiliated Hospital of Nanjing Medical University Jiangsu Province Hospital Nanjing China Yale Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, New Haven, CT;; Department of Chronic Disease Epidemiology; and School of Chemistry Beihang University No. 37, Xueyuan Road Beijing 100191 P. R. China Department of Human GeneticsMount Sinai School of Medicine New York New York 10029 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China; Institute of Functional and Molecular Medical Imaging, Fudan University, Shanghai, China Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China. Department of Thyroid and Breast Surgery, West China Hospital, Sichuan University, Chengdu 610041, China. Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center Yale University New Haven Connecticut USA; Department of Chronic Disease Epidemiology Yale School of Public Health New Haven Connecticut USA Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China MIRA Institute for Biomedical Technology and Technical Medicine; Department of Developmental Bioengineering; Faculty of Science and Technology; University of Twente; 7500 AE Enschede, The Netherlands Departments of Medicine, Pharmacology, and Biochemistry of The Mount Sinai School of Medicine, New York, New York 10029, and Laboratory for Mass Spectrometry and Gaseous Ion Chemistry, Rockefeller University, New York, New York 10021 1 Department of Computer Sciences, 1 University Station C0500, 2Department of Chemistry and Biochemistry, Institute for Cellular and Molecular Biology, Center for Systems and Synthetic Biology, 2500 Speedway, The University of Texas at Austin, Austin, TX 78712 ,3Pathogen Functional Genomics Resource Center, J. Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD 20850 and 4Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA College of Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331, P. R. China Department of Polymer Science and Engineering; Key Laboratory of High Performance Polymer Materials and Technology of Ministry of Education; State Key Laboratory of Coordination Chemistry; School of Chemistry and Chemical Engineering; Nanjing University Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China; Beijing Translational Engineering Center for 3D Printer in Clinical Neuroscience, Beijing, China Provincial Hospital Shandong University Jinan China Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of Education, and Wuhan University School of Pharmaceutical Sciences Wuhan P. R. China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China Faculty of Earth Science, China University of Geosciences, Wuhan 430074, China. State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China and Graduate School of Chinese Academy of Sciences, Beijing 100049, China Department of Oncology, The Cancer Center of the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China Department of Nephrology, Provincial Hospital Affiliated to Shandong University, Jinan 250021, China Corixa Corporation-Montana, Hamilton, Montana Departments of Neurosurgery and; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China Hubei Collaborative Innovation Centre for the industrialization of Major Grain Crops, College of Agriculture Yangtze University Jingzhou China Shanghai Institute of Forensic Science, Shanghai, China Research Center for Qinghai Healthy Development, Medical College, Qinghai University, Xining, Qinghai 810001, China; Department of Basic Medical Sciences, Medical College, Qinghai University, Xining, Qinghai 810016, China Department of Chemical and Biomolecular Engineering National University of Singapore Kent Ridge Singapore Department of Chemistry; Shanghai Normal University; Shanghai 200234, China Departments of Neurosurgery and; China National Clinical Research Center for Neurological Diseases (NCRC-ND);; Center of Stroke, Beijing Institute for Brain Disorders;; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease; Xiangya School of Public Health, Central South University, Changsha, Hunan 410001, China; School of Nursing, University of South China, Hengyang, Hunan 421001, China Beijing National Laboratory for Molecular Sciences, Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China; University of Chinese Academy of Sciences, Beijing 100049, P. R. China Department of Nephrology, Shandong Provincial Hospital, Shandong University, Jinan, China; Department of Nephrology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China Department of Diagnostic Radiology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi Province, China College of Life Sciences Yantai University Yantai China NMR Analytical Core Facility, Memorial Sloan Kettering Cancer Center, 417 East 68th Street, Room 1735, New York, New York 10065-6007, United States Singapore Membrane Technology Centre Nanyang Environment and Water Research Institute Nanyang Technological University 1 Cleantech Loop Singapore 637141 Singapore Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061, People's Republic of China. Key Laboratory of Xin'an Medicine; Ministry of Education; Hefei 230012 China; Anhui University of Chinese Medicine; Qian Jiang Road 1 Hefei 230012 China Cardiac Surgery, Chinese PLA General Hospital, Beijing 100853, China. State Key Laboratory of Tribology, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China. Department of Radiology Eye and ENT Hospital of Shanghai Medical School Fudan University Shanghai China Laboratory of Molecular Cardiology of Institute of Health SciencesShanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS) and Shanghai Jiao Tong University School of Medicine; Key Laboratory of Stem Cell Biology, SIBS; Graduate School of the CAS Shanghai China Department of Wound Repair, The First Affiliated Hospital of Hainan Medical University, Haikou 571000, China State Key Laboratory of Tribology, Tsinghua University, Beijing 100084, People’s Republic of China College of Life Science, Hebei Normal University, Shijiazhuang, P.R. China; Department of Pharmacy The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army Lanzhou China Department of Cardiology The Second Affiliated Hospital, Xi'an Jiaotong University Xi'an P.R. China Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University; and Departments of Genetics and Genomic Sciences and Structural and Chemical Biology, Mount Sinai School of Medicine, New York, NY 10029; and College of Food Science and Engineering Northwest A&F University Yangling Shaanxi 712100 P. R. China Department of Pharmacy, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; College of Integrated Chinese and Western Medicine, Jining Medical University, Jining 272067, China School of Mechanical and Automotive Engineering, Shanghai University of Engineering Science, Shanghai 201620, China Department of Pharmacy, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Department of Radiology Eye & ENT Hospital of Shanghai Medical School, Fudan University Shanghai P.R. China State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, People’s Republic of China Department of Endocrinology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, P.R. China School of Pharmaceutical Engineering & Life Science; Changzhou University; Changzhou 213164; P. R. China College of Forestry, Fujian Agricultural and Forestry University, Fuzhou, Fujian, China Research Institute of Atherosclerotic Disease, Xi’an Jiaotong University Cardiovascular Research Centre, Xi’an, Shaanxi 710061, China; Laboratory Animal Center, Xi’an Jiaotong University Health Science Centre, Xi’an, Shaanxi 710061, China Institute of Polymer Optoelectronic Materials & Devices, Key Laboratory of Luminescence from Molecular Aggregates of Guangdong Province, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, P. R. China State Key Laboratory of Silkworm Genome Biology Southwest University Chongqing 400716 China; Chongqing Key Laboratory of Microsporidia Infection and Control Southwest University Chongqing 400716 China; Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agricultural Southwest University Chongqing 400716 China Department of Laboratory Animal Science, School of Basic Medical Sciences, Xi’an Jiaotong University, Xi’an, People’s Republic of China; Cardiometabolic Innovation Center, Ministry of Education, Xi'an, People’s Republic of China Cancer Outcomes, Public Policy, and Effectiveness Research Center Yale University New Haven Connecticut; Department of Chronic Disease Epidemiology, School of Public Health Yale University New Haven Connecticut Department of Comprehensive Surgery, the Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China Digestive Endoscopy Center, Shanxi Provincial People's Hospital, Taiyuan, China; 1Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland. U. S. Department of Agriculture, Roman L. Hruska U.S. Meat Animal Research Center, Lincoln, Nebraska, USA Department of Polymer Science and Engineering, College of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China Jiangsu Key Laboratory of Translational Research and Therapy for Neuro‐Psycho‐Diseases and College of Pharmaceutical Sciences Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases Soochow University Suzhou Jiangsu P. R. China Department of Nephrology, Shandong Provincial Hospital Affiliated with Shandong University, Jinan, China; Department of Joint Surgery, Lanzhou General Hospital, Lanzhou Military Command, Lanzhou, China; Gansu University of Chinese Medicine, Lanzhou, China Key Laboratory for Agro‐Ecological Processes in Subtropical Region, Hunan Research Center of Livestock & Poultry Sciences, South‐Central Experimental Station of Animal Nutrition and Feed Science in the Ministry of Agriculture Institute of Subtropical Agriculture, The Chinese Academy of Sciences Beijing China; College of Animal Science and Technology Hunan Agricultural University Changsha China Department of Neurosurgery and Spinal Surgery The Affiliated Drum Tower Hospital of Nanjing University Medical School Nanjing China Department of Complex Tissue Regeneration MERLN Institute for Technology‐Inspired Regenerative Medicine Maastricht University Maastricht 6229 ER The Netherlands Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; NHC Key Laboratory of Clinical Nephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory of Nephrology, Guangzhou, China Early Life Evolution Laboratory, State Key Laboratory of Biogeology and Environmental Geology, China University of Geosciences, Beijing 100083, China. College of Chemistry and Chemical Engineering; Chongqing University; Chongqing 401331; People's Republic of China Department of Radiology, Gansu Provincial Hospital, Lanzhou, China College of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shaanxi China State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China Ecological Security and Protection Key Laboratory of Sichuan Province Mianyang Normal University Sichuan 621000 China; School of Ecological and Environmental Sciences Tiantong National Station of Forest Ecosystem East China Normal University Dongchuan Road 500 Shanghai 200241 China; School of Biology University of Leeds Leeds LS2 9JT UK 5Department of Chronic Disease Epidemiology, Yale School of Public Health, Yale University, New Haven, CT; Waksman Institute Rutgers, The State University of New Jersey, Piscataway, New Jersey 08855-0759 Department of Ultrasound, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221002, P.R. China School of biological and food engineering, Fuyang Teachers College, Fuyang 236037, China. wangrbnu@aliyun.com. Department of Gastrointestinal Surgery, The First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China 2Lanzhou General Hospital for PLA, Lanzhou, 730070, China Research Center for Environment and Female Reproductive Health The Eighth Affiliated Hospital Sun Yat‐sen University Shenzhen 518033 China Department of Neurosurgery, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY, USA National Clinical Research Center of Kidney Disease, Jinling Medical College of Nanjing Medical University, Nanjing, China;; Nephrology Department, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China College of Medicine, Qinghai University, Xining, Qinghai 810001, P.R. China Beijing Tian Tan Hospital, Capital Medical University, Beijing 100050, P.R. China Key Laboratory of High Performance Polymer Material and Technology of Ministry of Education, State Key Laboratory of Coordination Chemistry and Collaborative Innovation Center of Chemistry for Life Sciences, Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China Department of Protein Engineering, Beijing Institute of Biotechnology, Beijing, China School of Materials and Energy; Guangdong University of Technology; Guangzhou Higher Education Mega Center 100#; Guangzhou, P. R. China Department of Oncology, The Cancer Center of the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai 519000, China School of Pharmacy, State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, China; Key Laboratory for Prevention and Remediation of Plateau Environmental Damage, 940th Hospital of Joint Logistics Support Force of CPLA, Lanzhou, 730050, China Authors' Affiliations: 1Department of Urology, Union Hospital; 2Department of Pathogen Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; 3Cancer Biology Program, Hematology-Oncology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts; and 4Department of Neurology, Institute of Molecular Medicine and Genetics, Medical College of Georgia, Georgia Regents University, Augusta, Georgia School of Life Sciences, Tiangong University 1 , Tianjin 300387, China College of Life Sciences, Capital Normal University, Beijing, China Key Laboratory of Photosynthesis and Environmental Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, 20 Nanxincun, Xiangshan, Haidianqu, Beijing 100093, China. Department of Breast Surgery, the Affiliated Hospital of Guiyang Medical College, Guiyang, Guizhou, China Department of Pharmacy, Shanghai 9th People’s Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhi Zao Ju Rd, Shanghai 200011, China Lanzhou General Hospital, Lanzhou Command, Lanzhou 730050. The Rockefeller University Department of Pharmacy, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201999, China Department of Chemical and Biomolecular Engineering, 4 Engineering Drive 4, National University of Singapore, Kent Ridge, Singapore 117576 1Anatomy and Cell Biology and Departments of Key Laboratory of Modernized Chinese Medicine in Anhui Province, College of Pharmacy, Anhui University of Chinese Medicine, Hefei, Anhui, China 2Laboratory of Bacterial Pathogenesis and Immunology, The Rockefeller University, New York, NY 10021 State Key Laboratory of Reproductive Medicine The Research Center for Bone and Stem Cells Department of Anatomy, Histology and Embryology Nanjing Medical University Nanjing China Key Laboratory for Agro-Ecological Processes in Subtropical Region , Institute of Subtropical Agriculture, , Changsha, Hunan 410125 , China; Chinese Academy of Sciences , Institute of Subtropical Agriculture, , Changsha, Hunan 410125 , China Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China Department of Orthopaedics and Sport Medicine, Qingdao Municipal Hospital, Qingdao, China State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China. Yuncheng City Shengyitang Special Hospital of Hypersteogeny, Shanxi 044000, China. Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China Institute of Chemical Materials, China Academy of Engineering Physics (CAEP), P.O. Box 919-311, Mianyang 621999, Sichuan, China Department of Thyroid & Breast Surgery, West China Hospital, Chengdu 610041, China. National Research Institute for Family Planning, Beijing, China Chengdu Lilai Biotechnology Co., Ltd., Chengdu, Sichuan 610000, P.R. China Department of Hematology the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Collaborative Innovation Center for Cancer Personalized Medicine, Key Laboratory of Hematology of Nanjing Medical University Nanjing China Yale School of Public Health , New Haven, Connecticut , U.S.A. Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 119 South Fourth Ring West Road, Fengtai District, Beijing 100070, China; China National Clinical Research Center for Neurological Diseases, Beijing 100070, China; Center of Stroke, Beijing Institute for Brain Disorders, Beijing 100070, China; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing 100070, China; Beijing Translational Engineering Center for 3D Printer in Clinical Neuroscience, Beijing 100070, China Affiliated Hospital of Hubei University of Arts and Science, China Singapore Membrane Technology Centre, School of Civil and Environmental Engineering, Nanyang Technological University, Singapore Department of Pharmacy, Shanghai 9th People's Hospital Shanghai Jiao Tong University School of Medicine No. 280 Mohe Road Shanghai 201999 China Central Laboratory, Xuanwu Hospital, Capital Medical University, Key Laboratory for Neurodegenerative Disease of Ministry of Education, Beijing Geriatric Medical Research Center, No. 45 Changchun Street, Xicheng District, Beijing 100053, China; Center of Alzheimer's Disease, Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China. Nursing Department, Renmin Hospital of Wuhan University, Wuhan, China. Department of Genetics and Genomic Sciences, Icahn Institute, New York, New York 10029, United States NMR Analytical Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY 10065; Xi’ an University of Posts & Telecommunications College of Geography and Environmental Science, Northwest Normal University, Lanzhou 730070, China. Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China Laboratory of Reproductive Medicine, Research Center for Bone and Stem Cells Nanjing Medical University Nanjing China Department of Nephrology Shandong Provincial Hospital Affiliated to Shandong University Jinan Shandong China; Department of Nephrology Shandong Provincial Hospital Affiliated to Shandong First Medical University Jinan Shandong China Department of Polymer Science and Engineering, College of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China, and Key Laboratory of Molecular Engineering of Polymers, Ministry of Education, and Department of Macromolecular Science, Fudan University, Shanghai 200433, China Singapore Membrane Technology Centre. Nanyang Environment and Water Research Institute Nanyang Technological University 1 Cleantech Loop Singapore 637141 Singapore Forestry and Grassland Planning Institute of Qinghai Province Forestry and Grassland Administration of Qinghai Province Xining China Pathogen Molecular Genetics SectionLaboratory of Human Bacterial PathogenesisNational Institute of Allergy and Infectious DiseasesNational Institutes of HealthBethesdaMarylandUSA Key Lab of Plant Stress Research, College of Life Sciences, Shandong Normal University, Ji’nan, Shandong, China CAS Key Laboratory of Agro‐Ecological Processes in Subtropical Region, Hunan Research Center of Livestock and Poultry Sciences, South Central Experimental Station of Animal Nutrition and Feed Science in the Ministry of Agriculture, Institute of Subtropical Agriculture Chinese Academy of Sciences Changsha China Genetics and Genomic Sciences (G.D., R.W.), Mount Sinai School of Medicine, New York, New York 10029 Office of Biotechnology Products, CDER, FDA, Silver Spring, MD 20993, USA Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, and; Sino-French Institute for Earth System Science, Peking University, Beijing 100871, China; Department of Gastrointestinal Surgery, The Affiliated Hospital of Zunyi Medical College, Zunyi, Guizhou, China |
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