http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_a366819b69db12b0c84aea0bbcae69cf
Outgoing Links
| Predicate | Object |
|---|---|
| family-name | Li |
| name | Ji. Li Ji Li |
| given-name | Ji. Ji |
| organization-name | Department of Pancreatic Surgery, Huashan Hospital, Fudan University, Shanghai, The People's Republic of China Department of Rheumatology and Clinical Immunology Peking University First Hospital Beijing China Department of Dermatology, National Clinical Research Center for Geriatric Disorders Xiangya Hospital, Central South University 87 Xiangya Road Changsha Hunan 410008 China Division of Pancreas Huashan Hospital Fudan University Shanghai China Department of Orthopedics, General Hospital of PLA (People’s Liberation Army), Beijing, China (mainland) Department of Orthopedics, Center of Sport Medicine, Chinese PLA General Hospital, Beijing, China. Department of Pancreatic Surgery Pancreatic Disease Institute Huashan Hospital affiliated to Fudan University 12 Central Urumqi Road Shanghai 200040 China Department of Anatomy and Neurobiology, Xiangya School of Medicine Central South University Changsha China Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China; Key Laboratory of Molecular Radiation Oncology Hunan Province, Central South University, Changsha, China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Central South University, Changsha, China School of Pharmaceutical Science and Yunnan Key Laboratory of Natural Products Kunming Medical University Kunming Yunnan Province P. R. China Department of Gastroenterology Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College Beijing China The Sixth Department of Orthopaedics, General Hospital of Chinese PLA, Beijing 100853, China. Institute of Clinical Anatomy, Sourthern Medical University, Guangzhou 510515, China. hbtsliji@163.com Pancreatic Surgery Department Huashan Hospital Fudan University Shanghai China Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of Education; Jilin Normal University; Siping 136000; China Department of Pancreatic Surgery, Pancreatic Disease Institute, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, P.R. China University of Science and Technology of China 2 National Synchrotron Radiation Laboratory, , Hefei 230029, China Consultants in Epidemiology and Occupational Health (CEOH) LLC Washington District of Columbia USA; Department of Pathology Johns Hopkins School of Medicine Baltimore Maryland USA grid.452527.3 Environmental Science and Engineering Center Harbin Institute of Technology Shenzhen Graduate School 518055 Shenzhen Guangdong People’s Republic of China; Shenzhen Key Laboratory of Water Resource Utilization and Environmental Pollution Control 518055 Shenzhen Guangdong People’s Republic of China; Shenzhen Public Technological Service Platform for Urban Waste Energy Regeneration 518055 Shenzhen Guangdong People’s Republic of China; E417, HIT Campus Shenzhen University Town Xili 518055 Shenzhen People’s Republic of China Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China Department of Pathology, Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China Jiangsu Key Laboratory of Anaerobic Biotechnology School of Environment & Ecology Jiangnan University Wuxi 214122 China Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410017, China; Hunan Key Laboratory of Aging Biology, Xiangya Hospital, Central South University, Changsha 410017, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410017, China; Furong Laboratory, Changsha 410008, China Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China; Key Laboratory of Gut Microbiome and Translational Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China Department of Gastroenterology, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China. Department of Dermatology, Xiangya Hospital of Central South University, Changsha, Hunan, China; Hunan Key Laboratory of Aging Biology, Xiangya Hospital of Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital of Central South University, Changsha, Hunan, China Department of Pediatrics, Peking Union Hospital, Peking Union Medical University, Chinese Academy of Medical Sciences, Beijing 100730, China. Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China Department of Environmental Science and Engineering, Tsinghua Univerisity, Beijing 100084, China. School of Mechanical Engineering, Shenyang Jianzhu University, Shenyang 110168, China Jiangsu Collaborative Innovation Center of Biomedical Functional Materials; College of Chemistry and Materials Science; Nanjing Normal University; Nanjing; China Center for Mitochondria and Healthy Aging College of Life Sciences Yantai University Yantai 264005 P. R. China School of Civil and Environmental Engineering, Shenzhen Key Laboratory of Water Resource Application and Environmental Pollution Control, Harbin Institute of Technology (Shenzhen), Shenzhen 518055, P. R. China; State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, P. R. China Department of Anesthesiology The First Hospital of Jilin University Changchun Jilin China Center for Aggregation-Induced Emission; Institute of Polymer Optoelectronic Materials and Devices; Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates; State Key Laboratory of Luminescent Materials and Devices; South China University of Technology Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China; Hunan Key Laboratory of Aging Biology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China Department of Pharmaceutical Analysis, School of Pharmacy Second Military Medical University Shanghai PR China; Shanghai Key Laboratory for Pharmaceutical Metabolite Research Shanghai PR China School of Energy and Power Engineering, Huazhong University of Science and Technology, Wuhan 430074, China Department of Applied Chemistry; Key Laboratory of Space Applied Physics and Chemistry of Ministry of Education; School of Science; Northwestern Polytechnical University; Xi'an Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216, U.S.A. School of Industrial Engineering, Purdue University, West Lafayette, Indiana 47907, United States; Birck Nanotechnology Center, Purdue University, West Lafayette, Indiana 47907, United States Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, PR China Department of Physiology and Biophysics, Mississippi Center for Heart Research, University of Mississippi Medical Center, Jackson, MS 39216, USA Department of Pediatrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China. songhm1021@hotmail.com. School of Environment and Civil Engineering, Jiangnan University, Wuxi, China Department of Pathology Peking Union Medical College Hospital Beijing China Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College Chinese Academy of Medical Sciences Beijing China Departments of Cell Biology and Pathology, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320 Laboratory of Biosensing and MicroMechatronics, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031, China Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA, USA School of Civil and Environmental Engineering, Harbin Institute of Technology (Shenzhen), Shenzhen, Guangdong 518055, China The Key Laboratory of State Administration of Traditional Chinese Medicine of the People’s Republic of China, Department of Formulas of Traditional Chinese Medicine, School of Basic Medical Sciences, Heilongjiang University of Chinese Medicine, Harbin 150040, China Department of Dermatology, Xiang Ya Hospital, Central South University, Hunan, 410008, China, Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, 890-8520, Japan, and Department of Pharmaceutical Sciences, St. John’s University, New York 11439 Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China. Department of Orthopedics, The First Medical Center of Chinese People’s Liberation Army General Hospital, Beijing, China Department of Pharmacology and ToxicologyState University of New York at BuffaloBuffaloNew YorkUSA Department of Chemistry, University of Illinois at Urbana−Champaign, 600 S. Mathews Avenue, Urbana, Illinois 61801, United States Department of Clinical Pharmacy, Shanghai General Hospital, School of Medicine Shanghai Jiaotong University Shanghai P. R. China; School of Pharmaceutical Sciences and Yunnan Key Laboratory of Pharmacology for Natural Products Kunming Medical University Kunming P. R. China College of Sports Science, Harbin Normal University, Harbin 150025, China From the Department of Pharmacology and Toxicology, State University of New York at Buffalo, Buffalo, NY (J.W., C.T., X.Y., J.L.); Departments of Chemistry, Yale University, New Haven, CT (S.G., A.A.H., W.L.J.); Department of Medicine, Yale University of Medicine, New Haven, CT (X.D., L.L., L.H.Y., R.B.); Mt. Sinai School of Medicine, New York, NY (Y.C., H.X.); and Department of Biostatistics, State University of New York at Buffalo, Buffalo, NY (C.M.). Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, Heilongjiang 150001, China Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing , China The Center for Mitochondria and Healthy Aging College of Life Sciences Yantai University Yantai China Department of Gastroenterology Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China Key Lab of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 130022, China Department of Pharmaceutical Analysis, School of Pharmacy; Second Military Medical University; Shanghai P.R. China; Shanghai Key Laboratory for Pharmaceutical Metabolite Research; Shanghai P.R. China From the Department of Physiology, Fourth Military Medical University, Xi'an, China (H.M.); Divisions of Pharmaceutical Sciences (H.M., J.R., J.L.) and Kinesiology and Health (D.P.T.), University of Wyoming, Laramie; Department of Pharmacology and Toxicology, University at Buffalo–SUNY, Buffalo, NY (J.W., C.T., J.L.); Department of Medicine, Yale School of Medicine, New Haven, Conn (L.L., W.W., M.M., S.Z., R.B.); and University Hospital RWTH Aachen, Aachen, Germany (J.B.). Department of Dermatology Xiangya Hospital Central South University Changsha China; National Clinical Research Center for Geriatric Disorders Xiangya Hospital Central South University Changsha China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province Central South University Changsha China; Key Laboratory of Molecular Radiation Oncology Hunan Province Changsha China 1Genentech, Inc., South San Francisco, California. Department of Radiation Oncology, Eye, Ear, Nose & Throat Hospital of FuDan University Fenyang Road 83 Shanghai 200031 China Department of Spinal Surgery, The Second Hospital of Shandong University, Ji`nan, China Key Laboratory for Space Bioscience and Space Biotechnology, School of Life Sciences, Northwestern Polytechnical University, 127 YouyiXilu, Xi’an, Shaanxi 710072, People’s Republic of China Department of Physiology and Biophysics, Mississippi Center for Heart Research, University of Mississippi Medical Center, 2500 N State Street, Jackson, MS 39216, USA Department of Surgery, University of Maryland Medical School and Veterans Affairs Medical Center, Baltimore, Maryland 21201; and Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, University of Western Australia, Perth, WA, Australia; Authors' Affiliations: 1State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing; 2Institute of Cancer Stem Cell, Dalian Medical University Cancer Center, Dalian; 3Laboratory of Tumor and Molecular Biology, Beijing Institute of Biotechnology, Beijing; 4College of Biological Sciences, China Agricultural University, Beijing; 5College of Life Science, University of Science and Technology of China, Hefei; 6Department of Dermatology, Xiangya Hospital of China South University, Changsha; 7The Chinese Hippo Consortium, China; and 8Biological Sciences, The University of Chicago, Chicago, Illinois Laboratory of Cellular and Molecular Biology, National Institute on Aging-Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224 MIIT Key Laboratory of Critical Materials Technology for New Energy, Conversion and Storage, School of Chemistry and Chemical Engineering Harbin Institute of Technology Harbin 150001 P.R. China College of Chemistry and Chemical Engineering, Yantai University, Yantai, 264005, People's Republic of China Department of Haematology/Institute of Molecular Haematology the Second Xiang‐Ya Hospital Central South University Changsha Hunan China Department of Pancreatic Surgery, Huashan Hospital, Fudan University and Shanghai Medical School, Shanghai, P.R. China Department of Pathology Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College Beijing China Department of Pancreatic Surgery, Pancreatic Disease Institute, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China Dept. of Chinese Traditional Medicine, Huashan Hospital, Shanghai, China. Department of Chemistry, Beijing Key Laboratory for Microanalytical Methods and Instrumentation, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100084, China Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216 School of Basic Medical Sciences, North China University of Science and Technology (Hebei Key Laboratory for Chronic Diseases, Tangshan Key Laboratory for Preclinical and Basic Research on Chronic Diseases), Tangshan, Hebei 063000, P.R. China Harry Perkins Institute of Medical Research Centre for Medical Research QEII Medical Centre The University of Western Australia Perth WA Australia Hebei Key Laboratory for Chronic Diseases/Tangshan Key Laboratory for Preclinical and Basic Research on Chronic Diseases, School of Basic Medical Sciences, North China University of Science and Technology, Tangshan, Hebei 063000, P.R. China Second Clinical College, Chongqing Medical University, Chongqing 400016, China. E-mail: 77160520@qq.com. School Basic Medical Sciences, HUCM, Heilongjiang University of Chinese Medicine, Harbin 150040, China Division of Pharmaceutical Sciences and Center for Cardiovascular Research and Alternative Medicine, University of Wyoming, Laramie, Wyoming Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of Education; Jilin Normal University; Siping 136000; China; National Demonstration Center for Experimental Physics Education Department of Gastroenterology Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Beijing Key Laboratory of Biodiversity and Organic Farming, College of Resources and Environmental Sciences, China Agricultural University, 2 Yuanmingyuan West Road, Beijing 100193, China Department of Gastroenterology, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China Department of Radiation Oncology, Eye Ear Nose Throat Hospital of Fudan University, Shanghai, 200031, China. liji19781124@yahoo.com.cn Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of Education; Jilin Normal University; Changchun 130103; China cjst@cma.org Department of Dermatology Xiangya Hospital Central South University China; Center for Molecular Medicine Xiangya Hospital Central South University Changsha China Guangdong Provincial Key Laboratory of Applied Botany South China Botanical Garden Chinese Academy of Sciences Guangzhou China School of Aeronautic Science and Engineering, Beihang University, Beijing 100191, China; Chenghang Innovation Institute of Intelligent Aerocraft, Chengdu Aeronautic Polytechnic, Chengdu 610100, China Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai 201204 China Key Laboratory of Pathobiology, Department of Pharmacology, Ministry of Education, College of Basic Medicine, Jilin University, Changchun, Jilin 130021, China College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science and Technology, Xi’an, Shaanxi710021, China Key Laboratory of Space Applied Physics and Chemistry Ministry of Education, Department of Chemistry, School of Natural and Applied Science, Northwestern Polytechnical University Xi'an 710129 P. R. China Department of Pathology, The First Hospital and College of Basic Medical Sciences China Medical University Shenyang China Department of Gastroenterology, Shanghai Changning District Cental Hospital, Shanghai 200336, China Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, P.R. China Department of Pharmacology, College of Basic Medical Sciences, School of Nursing, Jilin University Longhua Hospital, Shanghai University of Traditional Chinese Medicine, No. 725 South Wanping Road, Shanghai 200032, China Shanghai Synchrotron Radiation Facility, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201204, China; Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China Department of Dermatology Xiangya Hospital Central South University Changsha China; Hunan Key Laboratory of Aging Biology Xiangya Hospital Central South University Changsha China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province Central South University Changsha China; Center for Molecular Medicine Xiangya Hospital Central South University Changsha China Department of Cell Biology and Physiology, University of Pittsburgh, S-326, 3500 Terrace Street, Pittsburgh, PA 15261, U.S.A. Department of Thoracic Surgery, The First People's Hospital of Neijiang Neijiang Affiliated Hospital of Chongqing Medical University Neijiang China Departement of Gastroenterology Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China cjst@cma.org.cn COVID‐19 Headquarters The First Affiliated Hospital of Wenzhou Medical University Wenzhou China Department of Dermatology, University of Oklahoma Health Sciences Center, Oklahoma City Department of Operation Room, The First Bethune Hospital of Jilin University, Changchun, Jilin 130021, P.R. China State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University , Nanjing 210023 , China Singleron Biotechnologies Nanjing China Department of Pharmacology and ToxicologySchool of Medicine and Biomedical SciencesUniversity at Buffalo–State University of New YorkBuffaloNew YorkUSA Department of Orthopedics General Hospital of PLA Beijing China Department of Chinese Formulae, Heilongjiang University of Chinese Medicine Institute of Fluid Physics, CAEP 1 , P.O. Box 919-106, Mianyang 621900, China Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, China; Hunan Key Laboratary of Aging Biology, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China Department of Radiation Oncology Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences Jinan China Genentech Inc., South San Francisco, California. State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing 210095, China.; State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing 210095, China. Department of AIDS Control and Prevention Center for Disease Control and Prevention of Jining Jining Shandong People's Republic of China College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science and Technology, Xi’an 710021, China Department of Hepatobiliary Surgery People's Hospital of Hechuan Chongqing 401520 P. R. China Department of Gynecology, The First Affiliated Hospital of Guangxi Medical University, Nanning City, China; Department of Obstetrics and Gynecology, The People’s Hospital of Cenxi City, Cenxi city, China Department of Hepatobiliary Surgery, Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. Department of Pathology Department of Pancreatic Surgery Huashan Hospital Fudan University Shanghai China Basic Biomedical Science Division, Sanford School of Medicine, University of South Dakota, Vermillion, South Dakota, 57069, USA Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China; Center for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Central South University, Changsha, China Pediatric Urology Department, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China Department of Neurology, Affiliated Hospital of Beihua University, Jilin 130021, China Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD Department of Pathology Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences Beijing China Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China; Center for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China Department of Integrated Traditional and Western Medicine, Huashan Hospital Fudan University Shanghai China Department of Trauma, Tangshan Second Hospital, Tangshan Hebei 063000, PR China. College of Bioinformatics Science and Technology Harbin Medical University China Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, China; Center for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Changsha, China Chengdu University of Information Technology. Department of Gastroenterology Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences Beijing China From the Section of Cardiovascular Medicine (S.J.B., J.L., R.R.R., E.J.M., L.H.Y.), Yale University School of Medicine, New Haven, Conn; the Institute of Cell Biology (D.N., R.T., T.W.), Swiss Federal Institute of Technology, ETH-Hoenggerberg, Zurich, Switzerland; the Department of Medicine and Biochemistry (R.L.H., L.A.W.), Dartmouth Medical School, and the Department of Biological Sciences, Dartmouth College, Hanover, NH. Department of Gastroenterology, The People’s Hospital of Yichun City, Yichun, Jiangxi, China Institute of Trauma Surgery, The Second Hospital of Tangshan, Tangshan, Hebei Province, China Department of Radiation Oncology, Eye and ENT Hospital of Fudan University, Xuhui District, Shanghai, China Department of Surgery, University of Maryland Medical School and Baltimore Veterans Affairs Medical Center, Baltimore, Maryland 21201 Department of Pharmacy, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, Shandong 266035, China Department of Dermatology Xiangya Hospital Central South University Changsha Hunan 410083 China Department of Respiratory & Critical Care Medicine, Hainan General Hospital, China. Hai Nan Province, Hai Kou City, Xiu Ying District, Xiu Hua Road, Number 19, 570311, China Department of Nephrology, Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, Qingpu District, Shanghai 201700, P.R. China Department of Chemistry, University of Illinois at Urbana—Champaign, 600 South Matthews Avenue, Urbana, Illinois 61801, United States College of Resources and Environmental Science, Beijing Key Laboratory of Biodiversity and Organic Farming, China Agricultural University , Yuanmingyuan West Road No. 2 , Haidian District, 100193 Beijing, China; Organic Recycling Institute (Suzhou) of China Agricultural University , Changli Road No.366 , Wuzhong District 215128, Jiangsu Province, China Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China; Hunan Key Laboratory of Aging Biology, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China Department of Translational Oncology, Genentech, South San Francisco, CA, USA Shanghai Jiao Tong University; Shanghai Key Laboratory of Advanced Manufacturing Environment Department of Pathology, Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College Beijing China Key Laboratory of Polymer Eco-materials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, People’s Republic of China Station of Post-doctorial Research, University of Chinese Academy of Sciences, Beijing 100049, China. School of Marxism, Yunnan Normal University, Kunming 650500, China. Novogene Bioinformatics Institute, Beijing, China Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250117, Shandong, China; Department of Oncology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China Suzhou Vicheck Biotechnology Co. Ltd., Suzhou 215128, China Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences , Beijing 100101 , China; Department of Geography, School of Geography and Information Engineering, China University of Geosciences , Wuhan 430078 , China State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Horticulture Nanjing Agricultural University Nanjing 210095 China Department of Dermatology, Central South University, XiangYa Hospital, Changsha, Hunan, China Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing 100044, China; Department of Rheumatology and Immunology, Peking University International Hospital, Beijing 102206, China Department of Dermatology, Guizhou Provincial People's Hospital, Guiyang, Guizhou 550002, P.R. China ENT Institute and Department of Otorhinolaryngology Eye & ENT Hospital, Fudan University Shanghai China; Department of Radiation Oncology Eye & ENT Hospital, Fudan University Shanghai China Department of Physiology and Biophysics, Mississippi Center for Heart Research, University of Mississippi Medical Center, Jackson, Mississippi 39216; Department of Physiology and Pathophysiology, School of Basic Medical Science, Capital Medical University, Beijing 100069, China Department of Engineering Thermophysics School of Energy and Power Engineering Huazhong University of Science and Technology Wuhan 430074 China Division of Clinical Outcome Assessment, Office of Drug Evaluation Sciences, Office of New Drugs, Center for Drug Evaluation and Research, United States Food and Drug Administration (US FDA), Silver Spring, Maryland, United States Department of Surgery, University of South Florida, Tampa (J.L.). Department of Nephrology Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University Shanghai People's Republic of China Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, China State Key Laboratory for Mesoscopic Physics and Electron Microscopy Laboratory, School of Physics Peking University Beijing P. R. China School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan, Shandong Province, China; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong Province, China Pathology, Peking Union Medical College (PUMC) Hospital, Chinese Academy of Medical Sciences and PUMC, Beijing, China Birck Nanotechnology Center, ‡School of Industrial Engineering, §School of Electrical and Computer Engineering, and ∥Department of Physics, Purdue University, West Lafayette, Indiana 47907, United States Department of Gastroenterology, Peking Union Medical College Hospital Chinese Academy of Medical Sciences Beijing China Department of Orthopedics, Qilu Hospital, Shandong University, Shandong 250012, P.R. China. Jiangsu Key Laboratory of Anaerobic Biotechnology School of Environment and Civil Engineering Jiangnan University Wuxi 214122 China Department of Pancreatic Surgery, Pancreatic Disease Institute Huashan Hospital, Fudan University Shanghai PR China College of Basic Medical Sciences, Heilongjiang University of Chinese Medicine, Harbin, China Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences Northwest, 2708 S. 48th St., Springdale, AR 72762, USA Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY 14214, USA Department of Integrated Traditional and Western Medicine, Huashan Hospital, Fudan University, Shanghai 200040. Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China; University of Chinese Academy of Sciences, Beijing 100049, China Department of Anesthesiology, The First Hospital of Jilin University, Changchun, Jilin, China (mainland) School of Bioresources Chemical and Materials Engineering, Shaanxi University of Science and Technology, Xi’an 710021, China Environmental Science and Engineering Center, Harbin Institute of Technology Shenzhen Graduate School, Shenzhen, People's Republic of China; Shenzhen Key Laboratory of Water Resource Utilization and Environmental Pollution Control, Shenzhen, People's Republic of China Center for Epidemiology and Environmental Health, CEOH, LLC, 3401 38th Street NW, Suite 615, Washington, DC 20016, USA; Department of Pathology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA Jiangsu Key Laboratory of Anaerobic Biotechnology, School of Environment and Civil Engineering, Jiangnan University, Wuxi 214122, China; Jiangsu College of Water Treatment Technology and Material Collaborative Innovation Center, Suzhou 215009, China Department of Respiratory Medicine, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu, China. Department of Respiratory Medicine, The Affiliated Jiangyin Hospital of Southeast University Medical College 163 Shoushan Road, Jiangyin 214400, China. SINOPEC (Beijing) Research Institute of Chemical Industry Co., Ltd., Beijing 100013, China Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai, Shandong 264005, P.R. China Department of Nephrology, Tongling People’s Hospital, Tongling, China Department of Anesthesiology, Zhujiang Hospital, Southern Medical University, 253 Industrial Road, Guangzhou City, Guangdong Province, China School of Industrial Engineering Purdue University West Lafayette IN 47907 USA; Birck Nanotechnology Centre Purdue University West Lafayette IN 47907 USA Pediatric Urology Department, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China; Digestive Endoscopy Center Shanghai Tongren Hospital Shanghai Jiaotong University School of Medicine Shanghai China International Institute for Earth System Sciences, Jiangsu Center for Collaborative Innovation in Geographical Information Resource Development and Application, Nanjing University, Nanjing, China. Department of Research and Development Operations, Amgen Inc., Thousand Oaks, CA, USA Department of Food Science, Rutgers University, 65 Dudley Road, New Brunswick, New Jersey 08901-8520, United States State Key Laboratory for Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, China; Fujian Cross Strait Institute of Flexible Electronics (Future Technologies), Fujian Normal University, Fuzhou, Fujian 350117, China Department of Radiation Oncology, Eye, Ear, Nose and Throat Hospital of Fudan University, Shanghai, China Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo-State University of New York, Buffalo, New York School of Industrial Engineering, Purdue University, West Lafayette, IN 47906 Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo-SUNY University of New York, Buffalo, NY 14214, USA Genentech, Inc. 1, South San Francisco, California 94080. Department of Pathology Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Central South University, Changsha, China; Center for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, China Department of Chemistry Beckman Institute for Advanced Science and Technology University of Illinois at Urbana–Champaign, 405 N Mathews Avenue Urbana IL 61801 USA Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China; Key Laboratory of Gut Microbiota Translational Medicine Research, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China Department of Pediatrics, Guang'anmen Hospital, Chinese Academy of Traditional Chinese Medicine, Beijing 100053, P.R. China School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan, China.; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, China. Department of ecological science and engineering, Beijing Key Laboratory of Biodiversity and Organic Farming, College of Resources and Environmental Sciences China Agricultural University Beijing China Department of Dermatology, Xiangya Hospital Central South University Changsha China; Hunan Key Laboratory of Aging Biology, Xiangya Hospital Central South University Changsha China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University Changsha China Center for Mitochondria and Healthy Ageing, College of Life Sciences, Yantai University, Yantai 264005, China Department of Nephrology Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University Shanghai China Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China; Hunan Key Laboratary of Aging Biology, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Central South Univerisity, Changsha, China Heilongjiang University of Chinese Medicine Harbin China Department of Pathology College of Basic Medical Sciences and First Affiliated Hospital of China Medical University Shenyang China Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, China Department of Pancreatic Surgery, Pancreatic Disease Institute, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China School of Civil and Environmental Engineering, Harbin Institute of Technology (Shenzhen), Shenzhen, Guangdong, P.R. China; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Nedlands 6009, Western Australia, Australia Beijing Key Laboratory of Biodiversity and Organic Farming, College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China School of Computer and Communication Engineering, Changsha University of Science and Technology, Changsha 410114, China Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Jinan, Shandong Province, China; Shandong Academy of Medical Sciences, Jinan, Shandong Province, China *Stress Signaling Unit, Laboratory of Cellular and Molecular Biology, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, MD 21224; and Department of Surgery Morsani College of Medicine University of South Florida Tampa Florida USA Department of Radiation Oncology Shandong Cancer Hospital and Institute Shandong First Medical University and Shandong Academy of Medical Sciences Jinan Shandong China Department of Infectious Diseases, The First Affiliated Hospital of Wenzhou Medical University, Hepatology Institute of Wenzhou Medical University, Zhejiang Key Laboratory of Hepatology, Wenzhou, 325000 Zhejiang, China Dentistry Teaching and Research Office, Heilongjiang University of Chinese Medicine, Harbin 150040, China Shenyang Aerospace University, Shenyang 110035, China Department of Pathology, Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China. Department of Molecular Biology, Genentech, 1 DNA Way, South San Francisco, CA 94080 Department of Integrated Traditional and Western Medicine, Huashan Hospital Fudan University, Shanghai, China Shenzhen University MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage; School of Chemistry and Chemical Engineering; Harbin Institute of Technology; Harbin; China Department of Thoracic Surgery, The First People’s Hospital of Neijiang, Neijiang Affiliated Hospital of Chongqing Medical University, Neijiang, Sichuan, China Shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai 201204 P. R. China; University of Chinese Academy of Sciences Beijing 100049 P. R. China Department of Anesthesiology, Zhujiang Hospital, Southern Medical University, Guangzhou City, Guangdong Province, China From the *Department of Pancreatic Surgery, Huashan Hospital; and †State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China. Environmental Science and Engineering Center, Harbin Institute of Technology Shenzhen Graduate School, Shenzhen, People’s Republic of China; Shenzhen Key Laboratory of Water Resource Utilization and Environmental Pollution Control, Shenzhen, People’s Republic of China; Shenzhen Public Technological Service Platform for Urban Waste Energy Regeneration, Shenzhen, People’s Republic of China Division of Pharmaceutical Sciences & Center for Cardiovascular Research and Alternative Medicine, University of Wyoming, Laramie, Wyoming. State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University , 210095 Nanjing , China Department of Gastroenterology, Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Beijing, China; Insitute of Silk Road Studies, Northwest University, Xi’an, China; From the Section of Cardiovascular Medicine (J.L, E.J.M., R.R.R., L.H.Y.), Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn; and the Department of Environmental and Molecular Toxicology (J.N.-T.), North Carolina State University, Raleigh, NC. School of Basic Medical Sciences, Heilongjiang University of Chinese Medicine, 24 Heping Road, Harbin, 150040, China Department of Gastroenterology First Hospital of Jilin University Changchun China Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China State Key Laboratory of Crop Genetics and Germplasm Enhancement College of Horticulture Nanjing Agricultural University Nanjing 210095 China School of Civil and Environmental Engineering, Shenzhen Key Laboratory of Water Resource Application and Environmental Pollution Control, Harbin Institute of Technology Shenzhen Graduate School, Shenzhen 518055, China Strait Laboratory of Flexible Electronics (SLoFE), Strait Institute of Flexible Electronics (SIFE, FutureTechnologies), Fujian Normal University, Fuzhou 350117, Fujian, P. R. China; Institute of Flexible Electronics, Northwestern Polytechnical University, Xi’an 710072, ShaanXi, P. R. China Department of Gastroenterology, The People’s Hospital of Yichun City, Jiangxi, China Institute of Materials Chemistry, Key Laboratory of Advanced Civil Engineering Materials, College of Materials Science and Engineering, Tongji University, 1239 Si-Ping Road, Shanghai 200092, China and Department of Chemical and Biomolecular Engineering, School of Science and Engineering, Tulane University, 6823 St. Charles Avenue, New Orleans Louisiana, Louisiana 70118-5698, USA Department of Chemistry, 600 S. Mathews Avenue, University of Illinois at Urbana−Champaign, Urbana, Illinois 61801, United States Department of Physiology and Biophysics, Mississippi Center for Heart Research, University of Mississippi Medical Center, 39216 Jackson, MS, U.S.A. State Key Laboratory of Coordination Chemistry Chemistry and Biomedicine Innovation Center (ChemBIC) School of Chemistry and Chemical Engineering Nanjing University Nanjing 210023 P. R. China GIPSA-Lab, Grenoble INP, CNRS, Université Grenoble Alpes, 38000 Grenoble, France Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Department of Cardiovascular Internal Medicine, The Second Affiliated Hospital of Guizhou Medical University, Kaili City, Guizhou Province, China College of Horticulture Nanjing Agricultural University Nanjing China; State Key Lab for Crop Genetics and Germplasm Enhancement Nanjing Agricultural University Nanjing China Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, 310003 Zhejiang Province, China; Department of Otolaryngology, The First people's Hospital of Ningbo City, 315010 Zhejiang Province, China Department of Gastroenterology, the First Affiliated Hospital of Xiamen University, Fujian China State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, P. R. China School of Medicine Tsinghua University Beijing China Department of Nephrology, Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, 1158 Gongyuan East Road, Qingpu District, Shanghai 201700, China Genentech, Inc., South San Francisco, California. Hunan Key Laboratory of Aging Biology, Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008, China School of Marxism, Yunnan Normal University, Kunming 650500, China. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, China Department of Pharmacology and Toxicology, School of Medicine University at Buffalo Buffalo NY USA Key Laboratory of Space Applied Physics and Chemistry, Ministry of Education, Department of Chemistry, School of Natural and Applied Science Northwestern Polytechnical University Xi'an P. R. China Key Laboratory of Forest Plant Ecology; Engineering Research Center of Forest Bio-Preparation Department of Chemical Engineering National Tsing Hua University 101, Sec. 2, Kuang‐Fu Rd. Hsinchu 30013 Taiwan; Department of Biomedical Engineering and Environmental Sciences National Tsing Hua University 101, Sec. 2, Kuang‐Fu Rd. Hsinchu 30013 Taiwan Department of Radiation Oncology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang, Liaoning, China (mainland) Department of Radiation Oncology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang 110042, China Pathological Department, Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China Dana-Farber Cancer Institute, Boston, United States Center for Mitochondrial and Healthy Aging, College of Life Sciences, Yantai University, Yantai, Shandong 264005, P.R. China Department of International Health; Johns Hopkins Bloomberg School of Public Health; Baltimore MD USA Department of Food Science, Rutgers, The State University of New Jersey, 65 Dudley Road, New Brunswick, New Jersey 08901, United States State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Horticulture, Nanjing Agricultural University, Nanjing, Jiangsu, China. Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY 14214, USA Department of Anesthesiology, The First Hospital of Jilin University, Changchun, China Department of Pathology Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of Pancreas Surgery Huashan Hospital Fudan University Shanghai China Department of Dermatology, Xiang-Ya Hospital, Central South University, Changsha, China Department of Ecology and Environmental Sciences, College of Resource and Environment and College of Natural Sciences, China Agricultural University, Beijing, 100094, People's Republic of China, and Department of Molecular Biosciences and Bioengineering, University of Hawaii, Hawaii 96822 School of Industrial Engineering, Purdue University, West Lafayette, IN 47907, USA; Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA Department of Pathology, OCS Microscopy Core, New York University School of Medicine and Cancer Institute 522 First Avenue, Smilow 1106 New York New York 10016 USA Beijing Key Laboratory of Biodiversity and Organic Farming, Department of Ecology and Ecological Engineering, College of Resources and Environmental Science, China Agricultural University,100193, Beijing, China; Organic Recycling Institute(Suzhou) of China Agricultural University,215128, Wuzhong, Jiangsu Province, China Department of Cardiology The Second Affiliated Hospital of Harbin Medical University Harbin People's Republic of China; National Key Laboratory of Frigid Zone Cardiovascular Diseases Harbin People's Republic of China 2Genentech, Inc., South San Francisco, CA 94080 Beijing Key Laboratory of Nanophotonics and Ultrafine Optoelectronic Systems and Micro-nano Centre, School of Physics, Beijing Institute of Technology, Beijing 100081, China Department of Gastroenterology, Chinese Academy of Medical Sciences & Peking Union Medical College Hospital, Beijing 100730, China College of Bioresources Chemical and Materials Engineering Shaanxi University of Science and Technology Xi'an 710021 People's Republic of China School of Pharmaceutical Sciences and Yunnan Key Laboratory of Pharmacology for Natural Products; Kunming Medical University; Kunming; P. R. China College of Public Health University of Oklahoma Health Sciences Center Oklahoma City Oklahoma Institute of Disaster and Emergency Medicine, Tianjin University, Tianjin, China Department of Spinal Surgery, The Second Hospital of Shandong University, Ji’nan 250033, China Department of Nephrology Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University Shanghai People’s Republic of China Key Laboratory of Advanced Optoelectronic Quantum Architecture and Measurement, Ministry of Education, School of Physics, Beijing Institute of Technology, Beijing, 100081, China Pathological Department Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, 381 Wushan Road, Guangzhou 510640, China Department of Orthopaedics, Shandong University Second Hospital, Jinan, China Department of Pathology Peking Union Medical College Hospital, Chinese Academy of Medical Sciences Beijing China Department of Pancreatic Surgery, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China School of Electronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu 611731, China The Key Laboratory of State Administration of Traditional Chinese Medicine of the People's Republic of China Department of Formulas of Traditional Chinese Medicine School of Basic Medical Sciences Heilongjiang University of Chinese Medicine Harbin 150040 China Department of Thoracic Surgery, Chongqing Public Health Medical Center, Chongqing, PR China Jiangsu Key Laboratory of Biofunctional Materials; School of Chemistry and Materials Science; Nanjing Normal University; Nanjing; P. R. China School of Environment and Civil Engineering, Jiangnan University, Wuxi 214122, China Department of Gastroenterology, Chinese Academy of Medical Sciences Peking Union Medical College Hospital Beijing China School of Medicine and Biomedical Sciences, University at Buffalo-SUNY, Buffalo, NY 14214, USA Department of Food Science, Rutgers University, 65 Dudley Road, New Brunswick, New Jersey 08901, United States Department of Clinical Nutrition, Xinhua Hospital, School of Medicine Shanghai Jiao Tong University Shanghai China Pharmacology Laboratory of Traditional Chinese Medicine, Longhua Hospital Shanghai University of Traditional Chinese Medicine Shanghai 200032 China Department of Cardiology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong 250021, China; Department of Pharmaceutical Sciences & Center for Cardiovascular Research and Alternative Medicine, Dept 3375, School of Pharmacy, University of Wyoming, Laramie, Wyoming 82071; Department of Endocrinology, Qilu Hospital, Shandong University, Jinan, Shandong 250012, China; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520; and Department of... Department of Dermatology Xiangya Hospital Central South University Changsha China Department of Dermatology Xiangya Hospital Central South University Changsha Hunan China; Center for Molecular Medicine Xiangya Hospital Central South University Changsha Hunan China Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of Education, Jilin Normal University, Changchun 130103, China Department of Pathology, Basic Medicine College China Medical University Shenyang China; Department of Pathology The First Affiliated Hospital of China Medical University Shenyang China Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201204, China The Key Laboratory of State Administration of Traditional Chinese Medicine of the People’s Republic of China, Department of Formulas of Traditional Chinese Medicine, School of Basic Medical Sciences, Heilongjiang University of Chinese Medicine Harbin 150040China State Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, College of Horticulture, Nanjing Agriculture University, Nanjing 210095, China Department of Physiology and Biophysics, Mississippi Center for Heart Research, University of Mississippi Medical Center, Jackson, Mississippi 39216 Department of Hematology, The Second Xiang-Ya hospital, Central South University, Changsha, Hunan, PR China Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China Department of Gynecology of Traditional Chinese Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China Chinese Academy of Sciences Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, , Guangzhou 510650, China; University of the Chinese Academy of Sciences , Beijing 100049, China Department of Dermatology Xiangya Hospital, Central South University Changsha Hunan China; Hunan key Laboratory of Aging Biology Xiangya Hospital, Central South University Changsha China; National Clinical Research Center for Geriatric Disorders Xiangya Hospital, Central South University Changsha Hunan China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province Changsha Hunan China Department of Chinese Formulae, Heilongjiang University of Chinese Medicine, Xiangfang, Harbin 150040, P.R. China University of Chinese Academy of Sciences Beijing 100049 P. R. China; Shanghai Synchrotron Radiation Facility Zhangjiang National Lab, Shanghai Advanced Research Institute Chinese Academy of Sciences Shanghai 201204 P. R. China Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China Department of Chemistry; University of Illinois at Urbana-Champaign; Urbana; USA Department of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Jiangning, PR China Department of Pediatrics, Peking Union Medical College Hospital, Peking Union Medical College Chinese Academy of Medical Sciences Beijing China 14Department of Hematology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Horticulture, Nanjing Agricultural University, Weigang Street No. 1, Nanjing 210095, China.; State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Horticulture, Nanjing Agricultural University, Weigang Street No. 1, Nanjing 210095, China. Department of Dermatology Xiangya Hospital Central South University Changsha China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province Central South University Changsha China; Center for Molecular Medicine Xiangya Hospital Central South University Hunan China; National Clinical Research Center for Geriatric Disorders Xiangya Hospital Central South University Changsha China Harbin Institute of Technology Shenzhen Graduate School; Shenzhen Key Laboratory of Water Resource Utilization and Environmental Pollution Control; Shenzhen Public Technological Service Platform for Urban Waste Energy Regeneration Department of Orthopedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China. Department of Gastroenterology Peking Union Medical College Hospital Dongcheng‐qu China Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences Northwestern Polytechnical Univ 127 Youyi Xilu Xi'an Shaanxi 710072 China Department of Nephrology Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, Qingpu District Shanghai P. R. China Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenyang, 110016, People's Republic of China. syphuliji@163.com. College of Bioinformatics Science and Technology, Harbin Medical University , Harbin 150081 , China Division of Gastroenterology, University of Calgary, Calgary, Alberta, Canada; Department of Gastroenterology, Peking Union Medical College Hospital, Beijing, China *Department of Molecular Biology, Genentech, Inc., South San Francisco, CA 94080; and College of Resources and Environmental Science, Beijing Key Laboratory of Biodiversity and Organic Farming, China Agricultural University, 100193, Beijing, China University of Oklahoma Health Sciences Center BGI-Shenzhen, Shenzhen 518083, China; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China School of Civil and Environmental Engineering, Shenzhen Key Laboratory of Water Resource Application and Environmental Pollution Control, Harbin Institute of Technology (Shenzhen), Shenzhen 518055, China; State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China Department of Gastroenterology Peking Union Medical College Hospital Chinese Academy of Medical Science Beijing China Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216, USA; G.V. (Sonny) Montgomery VA Medical Center, Jackson, MS 39216, USA Department of Gastroenterology Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA International Institute for Earth System Sciences, Nanjing University, Nanjing, Jiangsu, China; Environmental Sciences Division and Climate Change Science Institute, Oak Ridge National Laboratory, Oak Ridge, TN, USA Department of Acupuncture and Rehabilitation, The First Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China. Department of General Surgery, the Second Affiliated Hospital of Dalian Medical University, Dalian 116027, Liaoning Province, China. Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University Shandong Academy of Medical Sciences Jinan Shandong China Department of Orthopedics, Center of Sport Medicine, Chinese PLA General Hospital, Haidian, Beijing, China Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China; Department of Botany, Guangzhou Institute of Forestry and Landscape Architecture, Huangzhuang South Road 6, Baiyun District, Guangzhou 510540, China Department of Pancreatic Surgery, Pancreatic Disease Institute, Shanghai, China Department of Pharmacy, Qilu Hospital of Shandong University (Qingdao), Qingdao, China. Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China; Department of Pathology First Affiliated Hospital and College of Basic Medical Sciences China Medical University Shenyang China University of Arkansas, Fayetteville, AR, USA National Key Laboratory of Crop Genetics and Germplasm Enhancement Nanjing Agricultural University Nanjing 210095 China Department of Dermatology Xiangya Hospital Central South University Changsha China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province Central South University Changsha China; National Clinical Research Center for Geriatric Disorders Xiangya Hospital Central South University Changsha China; Center for Molecular Medicine Xiangya Hospital Central South University Changsha China; Department of Dermatology The Second Affiliated Hospital of Xinjiang Medical University Urumqi China Department of Anesthesiology, the First Hospital of Jilin University, Jilin,130021 China Institute of Quality Standard and Testing Technology Yunnan Academy of Agricultural Science, Supervision and Testing Center for Farm Product Quality Ministry of Agriculture Kunming China; Key Laboratory of Chemistry in Ethnic Medicinal Resources Yunnan Minzu University Kunming China Department of General Surgery, Chongqing Western Hospital, Chongqing 400051, P.R. China Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China Department of Anesthesia The First Hospital of Jilin University 71 XinMin Street Changchun 130021 P. R. China Department of Pathology College of Basic Medical Sciences China Medical University Shenyang China 1 Department of Paediatrics, 34732 Peking Union Medical College Hospital , Chinese Academy of Medical Sciences, Beijing, China. aDepartment of Cell Biology and The Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, Birmingham, Alabama 35294-0019 Jiangsu College of Water Treatment Technology and Material Collaborative Innovation Center, Suzhou 215009, China. Department of Gastroenterology, Key Laboratory of Gut Microbiota Translational Medicine Research, Chinese Academy of Medical Sciences Peking Union Medical College Hospital Beijing China Department of Food Science, Rutgers, the State University of New Jersey, 65 Dudley Road, New Brunswick, New Jersey 08901, United States College of Resource and Environment Sciences, China Agricultural University, Beijing 100094, China; Department of Molecular Biosciences and Bioengineering, University of Hawaii, Honolulu, Hawaii 96822; and School of Agricultural Biotechnology, Seoul National University, Seoul 151742, South Korea Shanghai Traditional Chinese Medicine Integrated Hospital Shanghai University of Traditional Chinese Medicine Shanghai China Department of Cardiology the 2nd Affiliated Hospital of Harbin Medical University Harbin China; Key Laboratory of Myocardial Ischemia, Ministry of Education Harbin Medical University Harbin China Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008, China. Department of Pharmacology and Toxicology, University at Buffalo, Buffalo, NY 14214, USA aDepartment of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294-0019; bThe Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, Birmingham, Alabama 35294-0019 Department of Internal Medicine, Section of Cardiovascular Medicine, and Department of Endoscopy, Tongren Hospital Shanghai Jiaotong University School of Medicine Shanghai China Department of Breast Surgery; Anesthesia surgery center College of Bioinformatics Science and Technology, Harbin Medical University , Harbin 150081, China Digestive Endoscopy Center, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111 Xianxia Road, Shanghai 200336, China Department of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China Department of Pharmacology and Toxicology School of Medicine and Biomedical Sciences University at Buffalo–State University of New York Buffalo New York USA Medical School of Chinese PLA, Beijing, China.; Department of Orthopedics, The First Medical Center, Chinese PLA General Hospital, Beijing, China. Jiangsu Key Laboratory of Biofunctional Materials College of Chemistry and Materials Science Nanjing Normal University Nanjing 210046 Jiang Su P.R. China Department of Radiation Oncology, Shandong Cancer Hospital & Institute, Shandong University Cancer Center, Shandong University, Jinan, Shandong, 250117, China; Department of Radiation Oncology, Shandong Cancer Hospital & Institute Affiliated to Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, Shandong, 250117, China State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai, China; Joint International Research Laboratory of Metabolic & Developmental Sciences, Shanghai Jiao Tong University, Shanghai, China; School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China Department of Spinal Surgery, The Second Hospital of Shandong University, Ji’nan, China Department of Pharmacology and Toxicology, University at Buffalo, The State University of New York, Buffalo, NY 14214; Department of Surgery, University of Maryland School of Medicine and Baltimore Veterans Affairs Medical Center, Baltimore, Maryland 21201 Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA. Department of Formulaology, School of Basic Medical Sciences, Heilongjiang University of Chinese Medicine, Harbin 150040, Heilongjiang Province, P.R. China. State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, People’s Republic of China Department of Orthopaedics, General Hospital of Chinese PLA, Beijing 100853, China. Department of Food Science, Rutgers University, 65 Dudley Road, New Brunswick, New Jersey 08901 Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China. Department of Physiology and BiophysicsMississippi Center for Heart ResearchUniversity of Mississippi Medical Center Jackson Mississippi USA Key Laboratory of Laboratory Medicine, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou 325000, China Birck Nanotechnology Center and School of Industrial Engineering, Purdue University, West Lafayette, Indiana 47906, United States Bioengineering Program, Department of Mechanical Engineering, University of Michigan, Dearborn, 4901 Evergreen Road, Dearborn, MI 48128, USA Department of Dermatology Xiangya Hospital, Central South University Changsha Hunan China; Hunan Key Laboratory of Aging Biology Xiangya Hospital, Central South University Changsha Hunan China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University Changsha Hunan China Department of Orthopedics, Sports Medicine Center, People’s Liberation Army General Hospital, No. 28 Fu Xing Road, Haidian District, Beijing 100853, P.R. 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