http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_46c9681b9e5be4145783021453cff390
Outgoing Links
| Predicate | Object |
|---|---|
| family-name | He Wei He |
| name | Wei He |
| given-name | Wei |
| organization-name | School of Nursing, Queensland University of Technology, Brisbane, Australia; School of Nursing, Nantong University, Nantong City, People’s Republic of China Respiratory and Critical Care Discipline, Central Hospital Affiliated to Shenyang Medical College, Shenyang , Liaoning,110024, China. Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China; Beijing Forestry University, Beijing 100083, China. hewei-11291@sina.com Department of Immunology, Research Center on Pediatric Development and Diseases, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, State Key Laboratory of Medical Molecular Biology, Beijing, China Department of Engineering Product Design, Singapore University of Technology and Design, 8 Somapah Road, 487372, Singapore College of Biotechnology and Pharmaceutical Engineering; Nanjing Tech University; Nanjing 211816; China Department of Physiology and Pharmacology (Q.L., R.L., P.S., R.R., W.H., Y.F., Y.H., H.S., L.T., J.H.Z., J.T.), Loma Linda University, CA.; Department of Pharmacy, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China (W.H.). Institute of Orthopaedics of Guangzhou University of Chinese Medicine China; The Third Affiliated Hospital of Guangzhou University of Chinese Medicine China Department of Ophthalmology Baodi Clinical College of Tianjin Medical University Tianjin China Department of General Surgery, Lichuan People’s Hospital, Lichuan College of Food Science and Engineering Bohai University Jinzhou China Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center , Smithville, TX 78957, USA Changshu Hospital Affiliated to Nanjing University of Chinese Medicine Changshu China Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Smithville, TX 78957, USA Department of Chemistry and Biochemistry and ‡Department of Cellular and Molecular Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0359, United States College of Chemistry and Chemical Engineering, Yangtze Normal University, Chongqing 408100, P. R. China Department of Orthopedic Surgery, General Hospital of Chinese People's Liberation Army, Beijing 100853, China. Department of Dermatology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. Ministry of Education Key Laboratory of Protein Science,; Tsinghua-Peking Joint Center for Life Sciences, Center for Structural Biology, and Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Department of Spine Surgery Beijing Jishuitan Hospital Beijing China Department of Radiology, Peking University Third Hospital, Beijing 100191, China Geno Biotech Co Ltd Shanghai 200300 China Surgical Intensive Care Unit, Beijing Tong Ren Hospital, Capital Medical University, Beijing 100730, China. icuhe@163.com *Department of Immunology, School of Basic Medicine, Peking Union Medical College, and Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, National Key Laboratory of Medical Molecular Biology, Beijing 100005, China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua-Peking Joint Center for Life Sciences, Tsinghua University, Beijing, 100084, PR China Department of Ultrasonography, Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, China; Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University Department of Ophthalmology, Wuzhou Workers’ Hospital, Wuzhou, Guangxi 543000, China College of Chemistry and Chemical Engineering, College of Pharmaceutical Sciences, and Institute of Modern Biopharmaceuticals, College of Life Sciences, Education Ministry Key Laboratory on Luminescence and Real-Time Analysis, Southwest University, Chongqing 400715, China, and AIDS and HIV Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China Department of Orthopaedics, First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou Guangdong, 510405, P.R. China. hewei1123@21cn.com Beijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Beijing 100190 China State Key Laboratory for Physical Chemistry of Solid Surfaces Fujian Key Laboratory of Materials Genome Collaborative Innovation Center of Chemistry for Energy Materials Department of Materials Science and Engineering College of Materials Xiamen University Xiamen 361005 P. R. China Department of Chemistry, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, Department of Chemistry, Duke University, Durham, North Carolina 27708, and Pittsburgh Supercomputing Center, Pittsburgh, Pennsylvania 15213 Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, National Health Council Key Laboratory of Digestive Diseases, State Key Laboratory for Oncogenes and Related Genes, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine Shanghai Jiao Tong University Shanghai China College of Materials Science and Engineering, Huaqiao University, Key Laboratory of Molecular Designing and Green Conversions (Fujian University), Xiamen 361021, China State Key Laboratory of Chemical Resource Engineering, Department of Organic Chemistry, Faculty of Science, Beijing University of Chemical Technology, Beijing 100029, People’s Republic of China Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong999777, China State Key Laboratory of Coordination Chemistry and Jiangsu Key Laboratory of Advanced Organic Materials School of Chemistry and Chemical Engineering Nanjing University 163 Xianlin Avenue Nanjing Jiangsu 210023 China; STA Pharmaceutical Co. Ltd. 90 Delin Road, Waigaoqiao Shanghai China Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, P.R. China Department of Spinal Surgery Beijing Jishuitan Hospital Beijing China Shanghai JiaoTong University School of Medicine, Ruijin Hospital, Department of Urology, Shanghai, 200025 China Department of Urology, Ruijin Hospital Affiliated to Medical College of Shanghai Jiao Tong University, Shanghai, China Department of Endocrinology and Metabolism The First Affiliated Hospital with Nanjing Medical University 300 Guangzhou Road Nanjing China College of Biotechnology and Pharmaceutical Engineering; Nanjing Tech University; Nanjing 211816; P. R. China State Key Laboratory of Optoelectronic Materials and Technologies Guangzhou Key Laboratory of Flexible Electronic Materials and Wearable Devices Nanotechnology Research Center School of Materials Science and Engineering Sun Yat‐sen University Guangzhou 510275 P.R. China State Key Laboratory of Power Transmission Equipment & System Security and New Technology, 400044, Chongqing, China Department of Medical Ultrasonics, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China Department of Nutrition and Food Hygiene, West China School of Public Health, Sichuan University, Chengdu 610041, China. School of Information Engineering, Baise University, Baise 533000, China State Key Laboratory of Oncology in South China Sun Yat‐Sen University Cancer Centre Guangzhou China; Department of Hepatobiliary Oncology Sun Yat‐Sen University Cancer Centre Guangzhou China Department of Gastroenterology, the Third Affiliated Hospital of Soochow University Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Welsh and McKean Roads, P.O. Box 776, Spring House, Pennsylvania 19477-0776 Department of Critical Care Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China. National Center for Evaluation of Agricultural Wild Plants (Rice), Department of Plant Genetics and Breeding China Agricultural University Beijing China *Multi-Organ Transplant Program, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada; and *Department of Chemistry and Department of Chemistry, University of Rochester, Rochester, New York 14627 Department of Thoracic Surgery, General Hospital of Ningxia Medical University, Ningxia, PR China Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China; HKUST Shenzhen Research Institute, No. 9 Yuexing 1st RD, South Area Hi-tech Park, Nanshan, Shenzhen 518057, China Department of Mechanical, Aerospace, and Biomedical Engineering and ‡Department of Materials Science and Engineering, The University of Tennessee, Knoxville, Tennessee 37996, United States Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, National Key Laboratory of Medical Molecular Biology, Beijing, China 1State Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, People’s Republic of China Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education College of Chemistry & Materials Science Northwest University Xi'an 710069 P. R. China Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China Research Center of Meridians Institute of Acupuncture and Moxibustion China Academy of Chinese Medical Sciences Beijing China Informatics of Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. Hewei555@hotmail.com Department of Anesthesiology, The Affiliated Hospital of Beihua University, Jilin City, Jilin Province 132000, China College of Life Science and Health, Wuhan University of Science and Technology, Wuhan 430065, China Department of Oncology The First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan 450052 P.R. China Department of Pediatrics, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, China. panjiahua1960@163.com. Department of Materials Science and Engineering, Department of Mechanical, Aerospace, and Biomedical Engineering, The University of Tennessee, Knoxville, Tennessee 37996, and Regeneration and Repair Laboratory, Department of Biomedical Engineering, Michigan Technological University, Houghton, Michigan 49931 School of Computer and Information Technology, Xinyang Normal University, Xinyang 464000, China Department of Clinical Psychology and Psychiatry, Zhejiang University School of Medicine, Hangzhou, China. Department of Medical Oncology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 511447, P.R. China Priority Medical Department, General Hospital of Central Theater Command, Wuhan, Hubei 430070, P.R. China Department of Orthopaedics Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, P. R. China;; Key Laboratory of Orthopaedics & Traumatology, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China; Vaccine Research Laboratory, Shanghai H&G Biotechnology Co. Inc., Shanghai, People's Republic of China. Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Division of Life Science, State Key Laboratory of Molecular Neuroscience, Guangdong-Hong Kong-Macau Joint Laboratory of Optoelectronic and Magnetic Functional Materials, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR 999077, China Department of Orthodontics School and Hospital of Stomatology Wenzhou Medical University Wenzhou Zhejiang 325027 China Translational Medicine Center, Honghui Hospital, Xi’an Jiaotong University, Xi’an, China The Key Laboratory for Silviculture and Conservation, Ministry of Education, Beijing Forestry University, Beijing 100083, PR China School of Pharmaceutical Sciences and Tsinghua-Peking Joint Centers for Life Science, Tsinghua University, Beijing 100084, China University of Science and Technology of China 6 Hefei National Laboratory for Physical Sciences at Microscale, , Hefei, Anhui 230026, People’s Republic of China Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Capital Medical University, Beijing 100069; Department of Thoracic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020 Jiangsu Key Laboratory for Microbes and Functional Genomics, Jiangsu Engineering and Technology Research Center for Industrialization of Microbial Resources College of Life Sciences, Nanjing Normal Univ. Nanjing Jiangsu Province 210023 China Department of Neurology, Xiangya Hospital, Central South University School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China College of Food Science Sichuan Agricultural University Ya'an P. R. China Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany Zhujiang Hospital, the First Military Medical University, Guangzhou 510282, Guangdong Province, China Department of Oncology, Wuhan Puren Hospital, Puren Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, Hubei 430081, P.R. China Department of Cardiothoracic Surgery, Zhongda Hospital, Medical School, Southeast University, Nanjing, China Key Laboratory of Advanced Metallic Materials of Jiangsu Province School of Materials Science and Engineering Southeast University Nanjing 211189 P. R. China College of Veterinary Sciences, Gansu Agricultural University, Lanzhou 730070, Gansu, China. Department of Hematology, The Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua 321000, Zhejiang Province, China. University of Science and Technology, Beijing, People's Republic of China School of Nursing, Nantong University, Nantong, Jiangsu PR China. Medical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, Guangdong, China; Maternal and Children Metabolic-Genetic Key Laboratory, Guangdong Women and Children Hospital, Guangzhou, Guangdong, China School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, P. R. China Guangdong Provincial Key Laboratory of Biotechnology for Plant Development , Guangzhou Key Laboratory of Subtropical Biodiversity and Biomonitoring, School of Life Sciences, , Guangzhou 510631 , China; South China Normal University , Guangzhou Key Laboratory of Subtropical Biodiversity and Biomonitoring, School of Life Sciences, , Guangzhou 510631 , China Lawrence Livermore National Laboratory Livermore California 94550 Institute of Animal Nutrition, Northeast Agricultural University, Harbin, PR China Gabriel N. Hortobagyi, University of Texas MD Anderson Cancer Center, Houston, TX; David Chen, Tetiana Taran, and David Lebwohl, Novartis Pharmaceuticals, East Hanover, NJ; Martine Piccart and Fabienne Lebrun, Université Libre de Bruxelles, Brussels; Ines Deleu, Oncology Centre, AZ Nikolaas, Sint-Nikolaas, Belgium; Hope S. Rugo, University of California, San Francisco; Ian Anderson, Redwood Regional Oncology Center, Santa Rosa, CA; Howard A. Burris, Sarah Cannon Research Institute, Nashville, TN;... Department of Joint Orthopaedic, The Third Affiliated Hospital, Guangzhou University of Chinese Medicine, 261 Longxi Avenue, Liwan, Guangzhou, Guangdong 510405, China; Institute of Orthopedics, Guangzhou University of Chinese Medicine, 261 Longxi Avenue, Liwan, Guangzhou, Guangdong 510405, China Department of Radiology, Peking University Third Hospital, China State Key Laboratory of Natural Medicines and ‡Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, PR China Massachusetts General Hospital Boston Massachusetts Department of Immunology, School of Basic Medical Science, Anhui Medical University, Hefei, Anhui 230032, P.R. China Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Chronic Disease Research Institute, the Children’s Hospital, and National Clinical Research Center for Child Health, School of Public Health, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Department of Nutrition and Food Hygiene, School of Public Health, Zhejiang University, Hangzhou, Zhejiang, China Department of Nutrition and Food Hygiene, Huaxi School of Public Health, Sichuan University, Chengdu 610041, Sichuan, China. Department of Chemistry Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction The Hong Kong University of Science and Technology Clear Water Bay, Kowloon Hong Kong China Department of Immunology Institute of Basic Medical Sciences Chinese Academy of Medical Sciences and School of Peking Union Medical College Beijing China; The National Key Laboratory of Medical Molecular Biology Beijing China Key Laboratory of Medical Cell Biology, Institute of Translational Medicine, China Medical University, Shenyang, Liaoning, China (mainland) State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, China; Department of Liver Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, China Department of Chemistry, Weldon School of Biomedical Engineering, Department of Pharmaceutics, and Oncological Sciences Center, Purdue University, West Lafayette, Indiana 47907 Aix Marseille Université, CNRS, Ecole Centrale Marseille, Institut Fresnel, 13013 Marseille, France State Key Laboratory of New Ceramics and Fine Processing; School of Materials Science and Engineering; Tsinghua University; Beijing 100084; China The First Affiliated Hospital Institute of Orthopedics Guangzhou University of Chinese Medicine Guangzhou China; The First Clinical Medical College Guangzhou University of Chinese Medicine Guangzhou China Tibet Institute for Conservation and Research of Cultural Relics, Lhasa 850000, People's Republic of China College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, 30 Puzhu Rd S., Nanjing 211816, China Guangxi Key Laboratory of Ocean Engineering Equipment and Technology, Qinzhou 535011, P.R. China; Key Laboratory of Beibu Gulf Offshore Engineering Equipment and Technology, Beibu Gulf University, Education Department of Guangxi Zhuang Autonomous Region, Qinzhou 535011, P.R. China Key Laboratory of Luminescent and Real-Time Analytical System (Southwest University), Chongqing Science and Technology Bureau, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, P. R. China NSF Center for Biophotonics Science and Technology Sacramento California 95817; Department of Radiation Oncology University of California,Davis, Medical Center Sacramento California 95817 School of Materials and Energy University of Electronic Science and Technology of China Chengdu China Department of Oral Medicine the First Affiliated Hospital of Zhengzhou University Zhengzhou People's Republic of China Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, Anhui, P.R. China; Department of Pharmacy, Binhu Hospital of Hefei City, The Third Affiliated Hospital of Anhui Medical University, Hefei 230001, Anhui, P.R. China Sichuan International Travel Healthcare Center and Port Clinic of Chengdu Customs, Chengdu, Sichuan, China Department of Medicinal Chemistry, SW 8 Rhône-Poulenc Rorer Central Research, 500 Arcola Road, Collegeville, Pennsylvania 19426 Department of Vascular Surgery, Sun Yat-sen University, Guangzhou, China. hewei.vi@163.com Department of Forensic Science School of Basic Medical Sciences Central South University Changsha Hunan Province P. R. China The authors’ affiliations are as follows: the Centre for Cancer Genetic Epidemiology, Departments of Public Health and Primary Care (L.D., S. Carvalho, J.A., K.A.P., Q.W., M.K.B., J.D., B.D., N. Mavaddat, K. Michailidou, A.C.A., P.D.P.P., D.F.E.) and Oncology (C.L., P.A.H., C. Baynes, D.M.C., L.F., V.R., M. Shah, P.D.P.P., A.M.D., D.F.E.), University of Cambridge, Cambridge, the Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine (A. Campbell, D.J.P.), and the... College of Horticulture and Forestry Sciences/Hubei Engineering Technology Research Center for Forestry Information Huazhong Agricultural University Wuhan China Chemical Manufacturing and Control, Adlai Nortye Ltd, Hangzhou, Zhejiang 311121, China *Multi Organ Transplant Program, Department of Pharmaceutics, School of Pharmaceutical Science, Hebei Medical University; CSPC Pharmaceutical Technology Co., Ltd. School of Science Dalian Maritime University Dalian 116026 P. R. China *Multi-Organ Transplant Program, 3Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA Department of Interventional Radiology, Guizhou Cancer Hospital, Cancer Hospital of Guizhou Medical University, Guiyang, Guizhou 550003, P.R. China Department of Orthopaedics, Third Affiliated Hospital Guangzhou University of Chinese Medicine Guangzhou China Key Laboratory of Resource Biology and Biotechnology in Western China Department of Life Science Northwest University Xi'an 710069 People's Republic of China State Key Laboratory for Physical Chemistry of Solid Surfaces, Fujian Key Laboratory of Materials Genome, College of Materials, Xiamen University, Xiamen 361005, China Division of Pediatric/Congenital Cardiology and Adult Congenital Heart Disease Program; Massachusetts General Hospital Heart Center; Harvard Medical School; Boston Mass USA Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, Hunan 410081, China Department of Neurosurgery Affiliated Aoyang Hospital of Jiangsu University Zhangjiagang China The First Clinical Medical School, Guangzhou University of Chinese Medicine Guangzhou 510405, China. State Key Laboratory of Physical Chemistry of Solid Surface Fujian Key Laboratory of Materials Genome Collaborative Innovation Center of Chemistry for Energy Materials College of Materials Xiamen University Xiamen 361005 China Doctor, Department of Critical Care Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing, China Department of Pharmaceutics, School of Pharmacy China Pharmaceutical University Nanjing 210009 P. R. China Department of Physics; University of Massachusetts Amherst; USA Beijing Forestry University, The Key Laboratory for Silviculture and Conservation, Ministry of Education, Beijing 100083, China School of Science, Dalian Maritime University, Dalian 116026, China He Eye Specialist Hospital, Shenyang, China Department of Gastroenterology, Xinqiao Hospital, The Army Military Medical University, Shapinba, Chongqing, China; School of Basic Medical Sciences, Anhui Medical University, Hefei, China College of Animal Science and Technology Northeast Agricultural University Harbin China School of Medicine and Tsinghua-Peking Joint Centers for Life Science; Tsinghua University; Beijing 100084; China Department of Physiology Hebei Medical University Shijiazhuang Hebei 050017 China Department of Cardiothoracic Surgery, Zhongda Hospital, Southeast University, Nanjing, P. R. China Cancer Research Institute Central South University Changsha Hunan China; Xi'an Children's Hospital Xi'an Shaanxi China Department of Materials Science and Engineering Fujian Key Laboratory of Materials Genome State Key Lab of Physical Chemistry of Solid Surface Collaborative Innovation Center of Chemistry for Energy Materials College of Materials and Pen‐Tung Sah Institute of Micro‐Nano Science and Technology Xiamen University Xiamen 361005 P. R. China Second Thoracic Surgery Ward Shengjing Hospital Affiliated to China Medical University Liaoning People’s Republic of China Gentic Medical Center Guangdong Women and Children Hospital Guangzhou China School of Pharmaceutical Science; Tsinghua University; Beijing; China Department of Dermatology Guiqian International General Hospital Guiyang China Department of Research and Development, Resgreen Group International Inc., Changsha, PR, China Department of Pharmacology, College of Medicine, Zhejiang University, Hangzhou 310031, China. Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021 School of Electronic Engineering, Xi’an University of Posts & Telecommunications, Xi’an 710121, China Department of Vascular Surgery, Zhongshan Hospital Fudan University Shanghai China Department of Chemistry; Department of Chemical and Biological Engineering; Hong Kong Branch of Chinese Nation-al Engineering Research Center for Tissue Restoration and Reconstruction; Institute of Advanced Study and Division of Life Science The Hong Kong University of Science and Technology, Clear Water Bay; Kowloon School of Electrical Engineering Chongqing University Chongqing China School of Chemistry and Chemical Engineering, Southeast University, Nanjing, Jiangsu 211189, People’s Republic of China Department of Gastroenterology The Second Affiliated Hospital of Army Medical University Chongqing China State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai Collaborative Innovation Center for Biomanufacturing (SCICB), Shanghai, China Department of Urology, Ruijin hospital, Shanghai Jiaotong University, school of medicine Shanghai, China. Beijing Institute of Technology Department of pharmacology and Pharmaceutical Sciences School of Medicine, Tsinghua-Peking Joint centers for Lifer Sciences Tsinghua University Beijing 100084 P. R. China State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine, Sun Yat‐sen University Cancer Center Guangzhou 510060 Guangdong P. R. China; Department of Liver Surgery Sun Yat‐sen University Cancer Center 651 Dongfeng Road East Guangzhou 510060 Guangdong P. R. China School of Materials and Energy, University of Electronic Science and Technology of China, Chengdu 610054, P. R. China Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, L.L.C, Welsh & McKean Roads, Spring House, Pennsylvania 19477-0776 School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China; Suzhou Xiangcheng Medical Materials Science and Technology Co., Ltd, Suzhou 215028, China First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China College of Biotechnology and Pharmaceutical Engineering Nanjing Tech University 30 Puzhu Rd S. Nanjing 211816 P.R. China College of Computer Science, Nankai University, Tianjin, China State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Department of Liver Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China Department of Ultrasonography, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China. Department of Materials Science and Engineering State Key Lab of Physical Chemistry of Solid Surface Collaborative Innovation Center of Chemistry for Energy Materials College of Materials and Pen‐Tung Sah Institute of Micro‐Nano Science and Technology Xiamen University Xiamen 361005 P. R. China Department of Cognitive Science Macquarie University Sydney NSW Australia College of Life Sciences, Nanjing Normal University, Nanjing, China;; Global Centre for Environmental Remediation (GCER), The University of Newcastle (UoN), Callaghan, Australia Department of Endocrinology, The People’s Hospital of China Medical University, The People’s Hospital of Liaoning Province, Shenyang, Liaoning P.R. China Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan Department of Nuclear Medicine, Huadong Hospital, Fudan University, Shanghai, China (mainland) Department of Physics; University of Massachusetts; Amherst, USA School of Pharmaceutical Sciences, State Key Laboratory of Cellular Stress Biology, Xiamen University, Xiamen 361102, Fujian, China College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, China Program in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore Zibo Park City Service Center, Zibo 255000, Shandong, China National Engineering Laboratory for Rice and By-Product Deep Processing, Central South University of Forestry and Technology, Changsha 410004, China Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital), Nanjing, Jiangsu 210029, China Department of Nuclear Medicine, Huadong Hospital Affiliated to Fudan University, Shanghai 200030, China Affiliated Hospital of Stomatology College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China Gannan Medical College, Ganzhou 341000. Chongqing University Research Center of Sensors and Instruments, College of Optoelectronic Engineering, , Chongqing 400044, China Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA MOE Key Laboratory of Resources Environmental Systems Optimization, North China Electric Power University, Beijing 102206, China Department of Urology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P.R. China College of Plant Protection, Henan Agricultural University, Zhengzhou, P.R. China Department of Critical Care Medicine Beijing Tongren Hospital, Capital Medical University Beijing China Division of General Internal Medicine, Massachusetts General Hospital, Boston School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, China; Department of Gastroenterology, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu 213003, P.R. China School of Materials Science & Engineering, University of Science & Technology Beijing, Beijing, 100083, PR China School of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China Institute of Orthopaedics of Guangzhou University of Traditional Chinese Medicine Guangzhou China; The Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine Guangzhou China Department of Critical Care Medicine Beijing Tongren Hospital Beijing Beijing China Contribution from the Department of Chemistry, University of Rochester, Rochester, New York 14627 State Key Lab of Physical Chemistry of Solid Surface, Fujian Key Laboratory of Materials Genome, Collaborative Innovation Center of Chemistry for Energy Materials, College of Materials, Xiamen University, Xiamen 361005, China Institute of High Energy Physics, Chinese Academy of Science, Beijing 100049, China Department of Neurology, Xiangya Hospital Central South University Changsha P.R. China; Hunan Provincial Cerebrovascular Disease Clinical Medicine Research Center Changsha P.R. China Department of Urology, Peking University Third Hospital, Beijing 100191, China The Department of Orthopedics The Third Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou China Department of Pharmaceutics; School of Pharmacy; China Pharmaceutical University; Nanjing 210009; P. R. China Department of Oncology Lombardi Comprehensive Cancer Center, Georgetown University Medical Center Washington District of Columbia USA Department of Orthopaedics, 1st Affiliated Hospital of Guangzhou Traditional Chinese Medicine University, Guangzhou Guangdong, 510405, P. R. China. hewei1123@21cn.com Institute of Orthopedics, Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Orthopedic, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Jinshazhou Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China Chronic Disease Research Institute, The Children’s Hospital, and National Clinical Research Center for Child Health, School of Public Health, School of Medicine, Zhejiang University, Hangzhou, China; Department of Nutrition and Food Hygiene, School of Public Health, Zhejiang University, Hangzhou, China; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University); Ministry of Education; College of Pharmaceutical Sciences; Southwest University; Chongqing 400716 Department of Materials Science and Engineering, State Key Lab of Physical Chemistry of Solid Surface, Collaborative Innovation Center of Chemistry for Energy Materials, College of Materials, Xiamen University, Xiamen 361005, China National Key Discipline and Orthopedic Laboratory Guangzhou University of Chinese Medicine Guangzhou Guangdong China Department of Dermatology, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai 201102, China College of Life Sciences, Northwest University, Xi'an 710069, China. Department of Stomatology The First Affiliated Hospital of Zhengzhou University Zhengzhou China Department of Diabetes and Endocrinology and; Department of Hematology and Hematopoietic Cell Transplantation, The Beckman Research Institute, City of Hope National Medical Center, Duarte, CA; and College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, P.R. China Third Xiangya Hospital Central South University Changsha Hunan China School of Information Science and Engineering, Hunan Institute of Science and Technology, Yueyang, China Department of Occupational and Environmental Health Sciences, School of Public Health Peking University Beijing China High Voltage and Electrical New Technology Key Laboratory of the Ministry of Education, Chongqing University Electrical Engineering College, Chongqing, China. Jiangsu Key Laboratory of Advanced Metallic Materials School of Materials Science and Engineering Southeast University Nanjing 211189 P.R. China MOE Laboratory for Earth Surface Process College of Urban & Environmental Sciences, Peking University Beijing China State Key Laboratory of Chemo/Biosensing and Chemometrics; College of Chemistry and Chemical Engineering; Hunan University; Changsha; P. R. China College of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110016, China Stronach Research Unit for Complementary and Integrative Laser Medicine, Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine and TCM Research Center Graz, Medical University of Graz, Auenbruggerplatz 29, 8036 Graz, Austria; Department of Meridians, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China Department of Orthopaedics, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 261 Longxi Road, Liwan District, Guangzhou 510378, China; Traumatology and Orthopedics Institute of Guangzhou University of Chinese Medicine, No. 261 Longxi Road, Liwan District, Guangzhou 510378, China Department of Nutrition and Food Hygiene, West China School of Public Health, Sichuan University, Chengdu. College of Mechanical Vehicle Engineering, Hunan University, Changsha, 410082, Hunan, P. R. China Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; Nanchang University, Nanchang 330031, China Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong (P. R. China), Department of Chemistry, The Fourth Military Medical University, Changle Road, Xi’an (P. R. China) Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China. Center for Reproductive Medicine Department of Obstetrics and Gynecology Southwest Hospital Chongqing China Department of Obstetrics & Gynecology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China. anyhewei@yahoo.com.cn Resgreen Group International Inc., Changsha 410329, China School of Laboratory Medicine, Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China State Key Laboratory of Fine Chemicals, Dalian University of Technology 1 , Dalian, Liaoning 116023, China; School of Chemical Engineering, Dalian University of Technology 2 , Dalian, Liaoning 116023, China Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16 Nanxiaojie Street, Dongzhimennei, Beijing 100700, China Hip Preserving Ward, No.3 Orthopaedic Region, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou Guangdong, 510405, P.R.China;Lab of Orthopaedics and Traumatology, Chinese Medicine of Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou Guangdong, 510405, P.R.China;Institute of Hip Diseases, Guangzhou University of Chinese Medicine, Guangzhou Guangdong, 510405, P.R.China.hw13802516062@126.com. Department of Urology, Peking University Third Hospital, Peking University, Beijing, China Nano Science and Technology Program, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong Massachusetts General Hospital Boston Massachusetts USA Stomatological Hospital of Zunyi Medical University, Zunyi Institute of Animal Nutrition, Northeast Agricultural University, Harbin 150030, China Department of Orthopaedics & Traumatology, Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, No.12, airport road, Baiyun distinct, Guangzhou city, Guangdong province, 510000, China; Department of Joint Diseases, Traumatology & Orthopedics Institute of Guangzhou University of Chinese Medicine, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou city, Guangdong province, 510000, China State Key Laboratory of Stem Cell and Reproductive Biology Institute of Zoology Chinese Academy of Sciences Beijing China; Institute for Stem Cell and Regeneration Chinese Academy of Sciences Beijing China; Beijing Institute for Stem Cell and Regenerative Medicine Beijing China; Savaid Medical School University of Chinese Academy of Sciences Beijing China Wenzhou Medical College, Zhejiang, China. Department of Ophthalmology, He Eye Hospital, Shenyang, China. HKUST-Shenzhen Research Institute , Shenzhen 518057 , China; Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology , Hong Kong , China Department of Endocrinology The First Affiliated Hospital of Nanjing Medical University Nanjing Jiangsu China Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing, China Department of Hepatopancreatobiliary Surgery Sun Yat-sen University Cancer Center Guangzhou, China State Key Laboratory of Oncology in South China Sun Yat-sen University Cancer Center Guangzhou, China Collaborative Innovation Center for Cancer Medicine Guangzhou, China Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry & Materials Science, Northwest University, Xi’an 710069, China Department of Respiratory Medicine, The Fifth People's Hospital of Shanghai Fudan University Shanghai China Department of Gastroenterology Chongqing Southeast Hospital Chongqing China Polaris Pharmaceuticals, San Diego, CA, USA; DesigneRx Pharmaceuticals, Shanghai, China State Key Lab of Physical Chemistry of Solid Surface, Collaborative Innovation Center of Chemistry for Energy Materials, College of Materials, Xiamen University, Xiamen 361005, China Department of Hepatobiliary Surgery, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, PR China General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA Department of Environmental Science, Zhejiang University, Hangzhou, China 310028, and Department of Tea Science, Zhejiang University, Hangzhou, Zhejiang, China 310029 Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China Department of Occupational Health, West China School of Public Health, Sichuan University, Chengdu 610041, China. Institutes of Biomedical Sciences, Shanxi University, Taiyuan, China. Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute of Advanced Study, Division of Life Science and State Key Laboratory of Molecular Neuroscience. The Hong Kong University of Science and Technology, Kowloon 999077, Hong Kong, China Sychrotron Radiation LaboratoryInstitute of High Energy PhysicsAcademia Sinica Beijing Peoples Republic of China Department of Anesthesiology, Guangdong Provincial People's Hospital, Guangzhou 510080, China Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, 1 Xian Nong Tan Street, Beijing 100050, P. R. China, Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medical Sciences, Peking Union Medical College, 5 Dongdan SanTiao, Beijing 100005, P. R. China, Department of Microbiology, University of Hong Kong, Pokfulam, Hong Kong SAR, P. R. China, Peking Union Medical College Hospital, Chinese... From the Departments of Neurology (F.C.C.) and Epidemiology and Biostatistics (P.B.), University of California San Francisco; the Department of Neurology (S.K.F.), Brigham and Women's Hospital, Boston; and the Division of General Medicine (W.H., S.R., J.B.M., V.A.T.), Program in Nutritional Metabolism (S.K.G., V.A.T.), and Division of Infectious Diseases (V.A.T.), Massachusetts General Hospital, Boston. Guangdong People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou. marinahewei@126.com Department of Hepato‐Pancreato‐Biliary Surgery 363 Hospital Chengdu China Department of Chemistry, School of Pharmacy, The Fourth Military Medical University The First Affiliated Hospital of Guangzhou University of TCM, Guangzhou 510405, Guangdong Province. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (W.H.). School of Water Resources and Environment, China University of Geosciences (Beijing), 100083 Beijing, China; Reproductive Medical Center Department of Obstetrics and Gynecology Southwest Hospital Third Military Medical University (Army Medical University Chongqing China School of Leisure and Digital Sports Guangzhou Sport University Guangzhou China Structure Research Laboratory, University of Science and Technology of China, Hefei, Anhui 230026, PRC, Scientific Research Institute of Shandong Ocean Chemical Industry, Shouguang, Shandong 262737, PRC, and National Key Laboratory of Crystal Materials, Institute of Crystal Materials, Shandong University, Jinan, Shandong 250100, PRC Department of Stomatology, The First Affiliated Hospital of Zhengzhou University The First Clinical School of Guangzhou University of Chinese Medicine , Guangzhou, Guangdong Province 510405, China; Guangdong Research Institute for Traumatology & Orthopedics , Guangzhou, Guangdong Province 510378, China Deparment of Orthopaedics, Xiamen Hospital of Traditional Chinese Medicine, Xiamen 361009, Fujian, China. Department of Critical Care Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China Department of Immunology, CAMS Key Laboratory T Cell and Cancer Immunotherapy, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, State Key Laboratory of Medical Molecular Biology, Beijing 100005, China Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan, China (mainland) State Key Laboratory for Strength and Vibration of Mechanical Structures, Xi'an Jiaotong University 1 , Xi'an 710049, People's Republic of China Traumatology and Orthopedics Institute Guangzhou University of Chinese Medicine Guangzhou Guangdong P.R. China; Department of Orthopaedics The Third Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou Guangdong P.R. China School of Nursing Nantong University Nantong China School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, China. Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, P.R. China; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, P.R. China Changchun University of Science and Technology, School of Computer Science and Technology, WeiXing Road, Changchun 130022, China Shaanxi Institute for Pediatric Diseases Xi'an Key Laboratory of Children's Health and Diseases Xi’an Children’s Hospital The Affiliated Children’s Hospital of Xi’an Jiaotong University) Xi’an, Shaanxi P.R. China Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Department of Urology, People's Hospital of Hangzhou Medical College, Zhejiang Provincial People's Hospital, 158 Shangtang Road Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China Division of Pediatric Cardiology; Massachusetts General Hospital, Harvard Medical School; Boston Massachusetts USA Tsinghua University, School of Medicine, Department of Biomedical Engineering, Beijing 100084, China International Institute for Earth System Science, Nanjing University, Nanjing, Jiangsu 210023, China.; Jiangsu Provincial Key Laboratory of Geographic Information Technology, Key Laboratory for Land Satellite Remote Sensing Applications of Ministry of Natural Resources, School of Geography and Ocean Science, Nanjing University, Nanjing, Jiangsu 210023, China. School of Chemistry and Chemical Engineering; University of Jinan; Jinan 250022; China Department of Biology, Developmental Biology Research Initiative, McGill University, Montreal, Quebec H3A 1B1, Canada MOE Laboratory for Earth Surface Processes College of Urban and Environmental Sciences Peking University Beijing 100871 China Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China Department of Urology, Xiangya Hospital, Central South University, Changsha, China. Department of Ultrasonography, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China (mainland) School of Pharmaceutical Sciences, Nanjing University of Technology, Nanjing 210009, China. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Chronic Disease Research Institute, The Children’s Hospital, National Clinical Research Center for Child Health, School of Public Health, School of Medicine, Zhejiang University, Hangzhou, China Department of Chemistry, School of Pharmacy Fourth Military Medical University Xi'an 710032 People's Republic of China Gentic Medical Center, Guangdong Women and Children Hospital, Guangzhou, China Pacing Electrophysiology Division, First Affiliated Hospital of Xinjiang Medical University, No. 137, Liyushan South Road, Urumqi, Xinjiang 830054, China College of Biotechnology and Pharmaceutical Engineering Nanjing Tech University, 30 Puzhu Rd S; Nanjing; China Department of Endocrinology and Metabolism The People's Hospital of China Medical University, The People's Hospital of Liaoning Province Shenyang P. R. China Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China Jiangsu Key Laboratory for Carbon‐Based Functional Materials & Devices Institute of Functional Nano & Soft Materials (FUNSOM) Soochow University Suzhou Jiangsu 215123 P.R. China Chronic Disease Research Institute, The Children's Hospital, and National Clinical Research Center for Child Health, School of Public Health, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China, Department of Nutrition and Food Hygiene, School of Public Health, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China, and Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (W.H.) Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian, Liaoning 116023, P. R. China, and Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R.China Department of Cardio-Thoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, China College of Food Science, Sichuan Agricultural University, Ya’an 625014, China Area 1 of Acupuncture, Moxibustion and Rehabilitation, Seventh People's Hospital of Nanning, Nanning 530012, Guangxi Zhuang Autonomous Region, China. Key Laboratory of Meat Processing of Sichuan, College of Food and Biological Engineering, Chengdu University, Chengdu 610106, China College of Electronic Countermeasures, National University of Defense Technology, Changsha 410073, China The Key Laboratory for Silviculture and Conservation of Ministry of Education, Beijing Forestry University, Beijing 100083 School of Basic Medical Science Anhui Medical University Hefei China The National Key Discipline and the Orthopedic Laboratory Guangzhou University of Chinese Medicine Guangzhou Guangdong P. R. China; Department of Orthopedics, First Affiliated Hospital Guangzhou University of Chinese Medicine Guangzhou Guangdong P. R. China State Key Laboratory of Bioorganic and Natural Products Chemistry, Collaborative Innovation Center of Chemistry for Life Sciences, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China Cyrus Tang Hematology Center Collaborative Innovation Center of Hematology Soochow University Suzhou P. R. China; National Clinical Research Center for Hematologic Diseases The First Affiliated Hospital of Soochow University Suzhou P. R. China; State Key Laboratory of Radiation Medicine and Protection Soochow University Suzhou P. R. China Division of Bioengineering, National University of Singapore, Singapore. Department of Physics; University of Massachusetts Amherst; , USA Institute of Parasitic Diseases, Sichuan Center for Disease Control and Prevention, Chengdu, China Medical Genetic Center, Guangdong Women and Children Hospital, Guangdong Women and Children Hospital, Guangzhou, Guangdong, China; Maternal and Children Metabolic-Genetic Key Laboratory, Guangdong Women and Children Hospital, Guangzhou, Guangdong, China; Thalassemia Diagnosis Center, Guangdong Women and Children Hospital, Guangzhou, Guangdong, China; Guangdong Birth Defect Prevention and Management Center, Guangzhou, Guangdong, China College of Information Engineering, China Jiliang University, Hangzhou, China Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, China State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, China State Key Hip Joints Center, First Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 12 Jichang Road, Guangzhou, Guangdong 510405, China Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Guangdong College of Pharmacy, Guangzhou 510240. College of Environmental Science and Engineering, North China Electric Power University, Beijing 102206, China National Joint Local Engineering Laboratory for Cell Engineering and Biomedicine Technique, Guizhou Province Key Laboratory of Regenerative Medicine, Key Laboratory of Adult Stem Cell Translational Research (Chinese Academy of Medical Sciences); Department of Clinical Medical College Guangdong Provincial Key Laboratory of Nutraceuticals and Functional Foods, College of Food Science, South China Agricultural University, Guangzhou, Guangdong 510642, P.R. China; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, Guangdong 510642, P.R. China Center for Research Information Science and Computing, Massachusetts General Hospital, Boston, Massachusetts; Department of Ophthalmology He Eye Specialist Hospital Shenyang China Department of Hepatobiliary Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang, China. College of Pharmaceutical Sciences, Gannan Medical University, Ganzhou, China Department of Surgery, University of Michigan Health System, Ann Arbor, Michigan, United States Department of Anesthesiology of Bengbu Jiao Tong Hospital,Bengbu 233000,China. State Key Laboratory of Agricultural Microbiology, Huazhong Agriculture University, Wuhan 430070, China. myway@webmail.hzau.edu.cn Guangzhou Institute of Microbiology Co., Ltd. Guangzhou China Department of Physical Medicine and Rehabilitation, The Affiliated Jiangyin People's Hospital of Southeast University Medical College, Wuxi, Jiangsu 214400, P.R. China Department of Urology, Peking University Third Hospital, Beijing, China The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China Orthopedic Department The First Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou China The Department of Orthopedics, First Affiliated Hospital Guangzhou University of Chinese Medicine Guangzhou Guangdong China; The Laboratory of Orthopaedics and Traumatology of Lingnan Medical Research Center Guangzhou University of Chinese Medicine Guangzhou Guangdong China Department of Pediatrics The Third Xiangya Hospital of Central South University Changsha China Department of Respiratory and Critical Care Medicine Central Hospital Affiliated To Shenyang Medical College Shenyang China Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16 Nanxiaojie, Dongzhimennei, Bejing 100700, China Department of Stomatology, Hubei Vocational and Technical College. Xiaogan 432000; China.E-mail:hbzyhewei@163.com. Cancer Biology and Genetics Program and Howard Hughes Medical Institute, Molecular Cytology Laboratory, and Departments of Neurology and Pathology, Memorial Sloan-Kettering Cancer Center, NY 10021 Department of Urology, The Chao Hu Hospital of Anhui Medical University, Hefei, China Department of Pharmacy, Second Affiliated Hospital Zhejiang University, School of Medicine Hangzhou China Department of Cell Biology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205 Department of Orthopaedics, the 305th Hospital of People's Liberation Army, Beijing 100017, China. Department of Building and Real Estate The Hong Kong Polytechnic University Hung Hom, Kowloon Hong Kong 999077 China The Key Laboratory of Chongqing Inorganic Special Functional Materials; College of Chemistry and Chemical Engineering; Yangtze Normal University; Chongqing 408100; China Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education; School of Biological Science and Medical Engineering; Beihang University; Beijing 100083; China Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA. School of Medicine and Tsinghua‐Peking Joint Centers for Life Science Tsinghua University Beijing 100084 P. R. China Department of Neurosurgery Qilu Hospital of Shandong University Qingdao China Department of Obstetrics and Gynecology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China. Chronic Disease Research Institute, The Children's Hospital, and National Clinical Research Center for Child Health, School of Public Health, School of Medicine Zhejiang University Hangzhou Zhejiang China; Department of Nutrition and Food Hygiene, School of Public Health, School of Medicine Zhejiang University Hangzhou Zhejiang China Department of Cognitive Science, Macquarie University, Sydney, NSW, Australia Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Ministry of Education, Tianjin, China. Key Laboratory of Advanced Metallic Materials of Jiangsu Province, School of Materials Science and Engineering, Southeast University, Nanjing 211189, P. R. China State Key Laboratory of Bioreactor Engineering, Shanghai Collaborative Innovation Center for Biomanufacturing (SCICB), East China University of Science and Technology, Shanghai 200237, China Department of Cognitive Science Macquarie University New South Wales Australia; Australian Research Council Centre of Excellence in Cognition and Its Disorders Macquarie University New South Wales Australia Liaoning He University, He Eye Hospital, Shenyang 110163, China. Email: hewei0111@163.com. Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden; Chronic Disease Research Institute the Children's Hospital, National Clinical Research Center for Child Health, School of Public Health, School of Medicine, Zhejiang University Hangzhou China; Department of Nutrition and Food Hygiene School of Public Health, Zhejiang University Hangzhou China He Eye Specialist Hospital, Shenyang, China. Gannan Medical College, Ganzhou, Jiangxi. School of Chemistry and Chemical Engineering, Yangtze Normal University, Chongqing, 408000, China Department of Obstetrics and Gynecology, Chengdu Women & Children’s Central Hospital, Chengdu, China Department of Endocrinology and Metabolism, The First Affiliated Hospital of Nanjing Medical University , Nanjing 210029 , China 1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Department of Integrated Traditional and Western Medicine, First Affiliated Hospital of Harbin Medical University, Harbin, China Novartis Pharmaceuticals Corporation, East Hanover, New Jersey Department of Chemistry Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction Division of Life Science and State Key Laboratory of Molecular Neuroscience Institute for Advanced Study and Department of Chemical and Biomedical Engineering The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong China Beijing Key Laboratory for Forest Pest Control, Beijing Forestry University, Beijing 100083, People’s Republic of China School of Electronics and Information Engineering, Changshu Institute of Technology, Changshu 215500, China Gene Targeting and Transgenic Facility University of Connecticut Health Center Farmington Connecticut Weldon School of Biomedical Engineering and Department of Chemistry, Purdue University, West Lafayette, IN 47907 Discovery Chemistry, ‡Non-clinical Safety,§Discovery Technologies, and ∥Discovery Oncology, Small Molecule Research, Pharma Research & Early Development, Hoffmann-La Roche Inc., pRED, 340 Kingsland Street, Nutley, New Jersey 07110, United States Department of Obstetrics and Gynecology Southwest Hospital Third Military Medical University Chongqing China Department of Ultrasound, The First Hospital Affiliated to Sun Yat-sen University, Guangzhou, Guangdong 510080, China.. Department of Thoracic Surgery Peking University Third Hospital Beijing China Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China Department of Medical Ultrasonics, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China Chronic Disease Research Institute The Children’s Hospital, and National Clinical Research Center for Child Health School of Public Health School of Medicine Zhejiang University Hangzhou Zhejiang China; Department of Nutrition and Food Hygiene School of Public Health School of Medicine Zhejiang University Hangzhou Zhejiang China Department of Oncology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China. Sichuan University Injury Control Research Center and Obesity and Body Composition Research Center; Baton Rouge LA Institute of Acupunture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China. Institute of Acu-Mox, China Academy of Chinese Medical Sciences, Beijing, China Mandel Center for Hypertension Research and Division of Cardiovascular Medicine, Department of Medicine, Duke University Medical Center, Durham, NC 27710 Department of Chemical and Biological Engineering; Department of Chemistry; Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction; Division of Life Science and Institute of Advanced Study; The Hong Kong University of Science and Technology Department of Liver Surgery Sun Yat‐sen University Cancer Center Guangzhou China; State Key Laboratory of Oncology in South China Sun Yat‐sen University Cancer Center Guangzhou China; Collaborative Innovation Center for Cancer Medicine Guangzhou China Obesity and Body Composition Research Center Chronic Disease Research Institute, Zhejiang University School of Public Health, School of Medicine Hangzhou China; Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden Department of Restorative Dentistry, School of Dentistry University of Washington Seattle Washington USA; The Key Laboratory of Oral Biomedicine The Affiliated Stomatological Hospital of Nanchang University Nanchang Jiangxi China Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Joint Orthopaedic, The Third Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China Affiliations of authors: Department of Medical Epidemiology and Biostatistics (WH, FF, HO, PH, KC), Clinical Epidemiology Unit (KES), and Department of Oncology-Pathology (SM), Karolinska Institutet, Stockholm, Sweden; Department of Oncology, South General Hospital, Stockholm, Sweden (SM, PH). School of Chemistry and Chemical Engineering Hunan University Changsha 410082 China Department of Orthopedics’, Hubei Hospital of Traditional Chinese Medicine, Wuhan, Hubei, P.R. China State Key Laboratory of Pharmaceutical Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Avenue, Nanjing 210093, China Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450052, P.R. China Guangdong Research Institute for Orthopedics & Traumatology of Chinese Medicine NO.261, Longxi Road, Liwan District 510378 Guangzhou P. R. China; The Third Affiliated Hospital of Guangzhou University of Chinese Medicine NO.261, Longxi Road, Liwan District 510378 Guangzhou P. R. China Department of Urology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University Shanghai, China. Jiangsu Key Laboratory for Carbon‐Based Functional Materials & Devices Institute of Functional Nano & Soft Materials (FUNSOM) Soochow University Suzhou Jiangsu 215123 P. R. China School of Mechanical Engineering, University of Science and Technology Beijing; Beijing 100083; China Department of Medical Services, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan 650000, P.R. China Science and Technology on Combustion Thermo‐Structure and Internal Flow Laboratory Northwestern Polytechnical University Xian 710072 China Department of Pediatrics, Third Xiangya Hospital, Central South University, Changsha 410013, China 1076244912@qq.com. Department of Chemistry, School of Pharmacy, Air Force Medical University, Xi’an, Shaanxi 710032, People’s Republic of China School of Chemistry and Chemical Engineering; Southeast University; Nanjing; China MOE Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China College of Biochemical Engineering, Beijing Union University, Beijing 100023, China Department of Orthopaedics, The First Affiliated Hospital of Soochow University , Suzhou 215006, China; Orthopaedic Institute, Medical College, Soochow University , Suzhou 215007, China State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academic of Sciences, Wuhan 430071, Hubei Province, China. Department of Chemistry School of Pharmacy Fourth Military Medical University Xi'an 710032 China Department of Urology, Xiangya Hospital of Central South University, Changsha, Hunan, China. College of Traditional Chinese Medicine Hebei North University Zhangjiakou Hebei China Department of Hematology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, People’s Republic of China School of Basic Medical Sciences Anhui Medical University Hefei Anhui 230032 China Department of Pulmonology and Critical Care Medicine, Tufts Medical Center , Boston, MA, 02111 , USA Reproductive Medical Center, Department of Obstetrics and Gynecology, Southwest Hospital , Army Medical University , 30 Gaotanyan Street, Shapingba District , Chongqing 400038 , P.R. China , Tel.: +86-23-13608356955, Fax: +86-23-68754410 School of Electrical Engineering, Chongqing University, Chongqing 400044, China Department of Chemistry; Weldon School of Biomedical Engineering; School of Health Sciences; Purdue University, West Lafayette, Indiana 47907 Institute of Biothermal Science & Technology, University of Shanghai for Science and Technology, Shanghai 200093, China; Shanghai Co-innovation Center for Energy Therapy of Tumors, Shanghai 200093, China; Shanghai Technical Service Platform for Cryopreservation of Biological Resources, Shanghai 200093, China James C. Yao, University of Texas MD Anderson Cancer Center, Houston, TX; Maurizio Voi, Wei He, and David Chen, Novartis, East Hanover, NJ; Timothy Hobday, Mayo Clinic College of Medicine, Rochester, MN; Rodney Pommier, Oregon Health & Science University, Portland, OR; Marianne Pavel, Charité Universitätsmedizin, Berlin, Germany; Catherine Lombard-Bohas, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France; Eric Van Cutsem, University Hospitals Gasthuisberg/Leuven and KU Leuven, Leuven,... Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200050, China Department of Clinical Laboratory, The Second Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610041, China. Department of Chemical and Biological Engineering, Department of Chemistry, and Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China State Key Laboratory of Targeting Oncology, National Center for International Research of Bio-Targeting Theranostics, Guangxi Key Laboratory of Bio-Targeting Theranostics, Collaborative Innovation Center for Targeting Tumor Diagnosis and Therapy, Guangxi Medical University, Nanning 530021, China Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. Altay Gebao Tea Co., Ltd. Altay 836300, China. Department of Developmental Biology Key Laboratory of Cell Biology Ministry of Public Health China Medical University Heping District Shenyang China; Key Laboratory of Medical Cell Biology Ministry of Education China Medical University Heping District Shenyang China Drug Discovery, Johnson & Johnson Pharmaceutical Research and Development, L.L.C., Welsh & McKean Roads, P.O. Box 776, Spring House, Pennsylvania 19477 Polaris Group, San Diego, CA, USA Department of Respiratory Medicine, Affiliated Center Hospital of Shenyang Medical College, Shenyang, P. R. China Beijing Information Science and Technology University The College of Forestry, Beijing Forestry University, Beijing 100083, China; Department of Gastroenterology, Geriatric Hospital of Nanjing Medical University, Nanjing, Jiangsu 210024, P.R. China Division of Physical Biology and Bioimaging Center CAS Key Laboratory of Interfacial Physics and Technology Shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai 201800 P. R. China; University of Chinese Academy of Sciences Beijing 100049 P. R. China Department of Hand Surgery, the Third Hospital of Hebei Medical University, Shijiazhuang 050051, Hebei Province, China. Dalian Medical University, Dalian, China.; He Eye Specialist Hospital, Shenyang, China. MOE Joint International Research Laboratory of Animal Health and Food Safety, Engineering Laboratory of Animal Immunity of Jiangsu Province, College of Veterinary Medicine Nanjing Agricultural University Nanjing China Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 999077, P. R. China School of Automation and Electrical Engineering, University of Science and Technology Beijing, Beijing, China Zhejiang DTRM Biopharma LLC Plymoth Meeting Pennsylvania USA Department of Gastroenterology, Jiangsu Province Geriatric Hospital, Nanjing, China Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, China.; Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China. Department of Orthopaedics Surgery First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine Guangzhou China; Key Laboratory of Orthopaedics & Traumatology Guangzhou University of Traditional Chinese Medicine Guangzhou China Southern Medical University, Guangzhou 510515, China. 271463017 @qq.com Department of Chemistry, School of Pharmacy, Fourth Military Medical University, Shaanxi Province, Xi’an 710032, P.R. China Nuclear Medicine, Fudan University Huadong Hospital; School of Electronic Engineering, Xi'an University of Posts and Telecommunications , Xi'an 710121 , China Long-term Research Station of Alpine Forest Ecosystems, Institute of Ecology and Forest, Sichuan Agricultural University, Chengdu 611130, People’s Republic of China. Collaborative Innovation Center of Ecological Security in the Upper Reaches of Yangtze River, Chengdu 611130, People’s Republic of China.; Long-term Research Station of Alpine Forest Ecosystems, Institute of Ecology and Forest, Sichuan Agricultural University, Chengdu 611130, People’s Republic of China. Collaborative Innovation Center of Ecological Security in the Upper Reaches of Yangtze River, Chengdu 611130, People’s Republic of China. Multi-Organ Transplant Program, Toronto, Ontario, Canada Jiangsu Provincial Geriatric Hospital, Jiangsu, China Department of Neurosurgery, Qilu Hospital of Shandong University, Qingdao 266035, China Key Laboratory of Orthopaedics & Traumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, P.R. China Department of Ultrasonography, The Third Xiangya Hospital of Central South University Changsha 410013, China. State Key Laboratory of Magnetism and Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China Ningbo Institute of Material Technology and Engineering Chinese Academy of Sciences Ningbo 315201, P. R. China Department of Orthopedics, Guangdong Research Institute for Orthopedic & Traumatology of Chinese Medicine, Guangzhou , Guangdong 510240 , China; Department of Joint Orthopaedic, The Third Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou , Guangdong 510240 , China School of Nursing, Nantong University, Nantong City, Jiangsu Province, People’s Republic of China; School of Nursing, Queensland University of Technology, Kelvin Grove, Queensland, Australia Guangdong Research Institute for Orthopedics and Traumatology of Chinese Medicine , No. 261, Longxi Road, Liwan District, Guangzhou 510378, P.R. China; Joint Center, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine , No. 261, Longxi Road, Liwan District, Guangzhou 510378, P.R. China Key Laboratory of Petroleum Resources Research, Gansu Province, Northwest Institute of Eco-Environment and Resources, Chinese Academy of Sciences, Lanzhou 730000, PR China; University of Chinese Academy of Sciences, Beijing 100049, China Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University Medical School, Shanghai, China Institute of Infectious Diseases, The First Affiliated Hospital of Medical College, Zhejiang University, Key Laboratory of Infections Diseases, Ministry of Public Health, Hangzhou 310003, China. Department of Vaccine Research, Changchun Zhuoyi Biological Co., Ltd., Changchun, China. State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Fujian Agriculture and Forestry University, Fuzhou 350002, China; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, PR China; Institute of Hip Joint, Guangzhou University of Chinese Medicine, Guangzhou, PR China School of Public Health, Chongqing Medical University, Chongqing 400016, China University of Science and Technology of China Hefei National Laboratory for Physical Sciences at Microscale, , Hefei, Anhui 230026, China State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory Disease Guangzhou Institute of Respiratory Health the First Affiliated Hospital of Guangzhou Medical University Guangzhou China Department of Ophthalmology, Baodi Clinical College, Tianjin Medical University, Tianjin, China; Department of Ophthalmology, Baodi Clinical College, Tianjin Medical University, Tianjin, China Beijing Forestry University, The Key Laboratory for Silviculture and Conservation, Ministry of Education, Beijing 100083, PR China Key Laboratory of Integrated Pest Management on Crops in Northwestern Oasis Ministry of Agriculture, Institute of Plant Protection, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, China Department of Ultrasound Institute of Diagnostic and Interventional Ultrasound The First Affiliated Hospital of Sun Yat-sen University Guangzhou China Northwest Evaluation Association, Portland, OR, USA Department of Obstetrics and Gynecology, Reproductive Medical Center, Southwest Hospital, Army Medical University Third Military Medical University Chongqing China Department of Immunology, School of Basic Medicine, Peking Union Medical College, and Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100005, China. College of Basic Medical Sciences, Shaanxi College of Chinese Medicine, Shaanxi (712046), China. Chronic Disease Research Institute, The Children’s Hospital, and National Clinical Research Center for Child Health, School of Public Health, School of Medicine, Zhejiang University , Hangzhou, Zhejiang , China; Department of Nutrition and Food Hygiene, School of Public Health, School of Medicine, Zhejiang University , Hangzhou, Zhejiang , China Department of Neurology The First Affiliated Hospital of Chongqing Medical University Chongqing China ∥Department of Immunology, Institute of Basic Medical Sciences, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China; and Guangdong Research Institute for Orthopedics & Traumatology of Chinese Medicine , No. 261, Longxi Road, Liwan District, Guangzhou 510378, P.R. China Department of Parasitology, Zunyi Medical University, Zunyi 563000, China Department of Orthopedics First Affiliated Hospital, Guangzhou University of Chinese Medicine Guangzhou China; Lingnan Medical Research Center of Guangzhou University of Chinese Medicine Guangzhou China State Key Laboratory of Oral Diseases, West China College of Stomatology, Sichuan University, Chengdu, People's Republic of China, Department of Cleft Lip and Palate Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, People's Republic of China School of Materials Science and Engineering University of Science and Technology Beijing Beijing China MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, Jiangsu Engineering Laboratory of Animal Immunology, Institute of Immunology, College of Veterinary Medicine, Nanjing Agricultural University Department of Pharmaceutics, School of Pharmaceutical Science, Hebei Medical University, 361, ZhongShan East Road, ShiJiaZhuang, 050017, PR China. Department of Mechanical, Aerospace, and Biomedical Engineering University of Tennessee Knoxville Tennessee 37996; Department of Materials Science and Engineering University of Tennessee Knoxville Tennessee 37996; Department of Polymer Science and Engineering Dalian University of Technology Dalian Liaoning 116023 China McGill AIDS Centre, Lady Davis Institute-Jewish General Hospital, Montreal, Quebec, Canada H3T 1E2; Department of Medicine, Bond Life Sciences Center, University of Missouri, Columbia, Missouri 65211-7310 School of Basic Medical Sciences，Shaanxi University of Chinese Medicine, Xianyang 712046, China. School of Pharmaceutical Sciences Tsinghua University Beijing 100084 P. R. China Center for Research Information Science and Computing, Massachusetts General Hospital, Boston, Massachusetts Department of Pharmacy, Wuhan No. 1 Hospital, 215 Zhongshan Street, Wuhan 430022, China Department of Urology, the First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan 450000, China. College of Pharmaceutical Sciences; Southwest University; Chongqing 400715; P. R. China Division of General Internal Medicine Massachusetts General Hospital Boston MA College of Life Science, Northwest University, Xi’an 710069, China; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi’an 710032, China Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, 230026, People's Republic of China; Key Laboratory of Structural Biology, Chinese Academy of Sciences, Hefei, Anhui, 230026, People's Republic of China State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine Sun Yat‐Sen University Cancer Center Guangzhou China; Department of Hepatobiliary Oncology Sun Yat‐Sen University Cancer Center Guangzhou China Department of Urology, Shanghai JiaoTong University School of Medicine, Ruijin Hospital, Shanghai, China He University, Shenyang, China Lawrence Livermore National Laboratory, Livermore, California 94550, United States Department of Surgery, Guizhou Orthopaedic Hospital, Guiyang NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China Department of Urinary Surgery Shanghai Ruijin Hospital Shanghai China School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, P.R.China;Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, 100083, P.R.China. 1Discovery Oncology, State Key Laboratory of Optoelectronic Materials and Technologies Guangzhou Key Laboratory of Flexible Electronic Materials and Wearable Devices Nanotechnology Research Center School of Materials Science and Engineering Sun Yat‐sen University Guangzhou 510275 P. R. China Department of Orthopedics, The 305 Hospital of Chinese PLA, Beijing 100017, China College of Optoelectronic Engineering Research Center of Sensors and Instruments, , Chongqing University, Chongqing 400044, China School of Chemical Sciences University of Chinese Academy of Sciences. Beijing 100049 P. R. China Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China. Jiangsu Province Engineering Research Center for Marine Bio-resources Sustainable Utilization and College of Oceanography, Hohai University, Nanjing, PR China School of Pharmacy, China Pharmaceutical University, Nanjing, China (W.H., M.M.) Department of Urology, the Chao Hu Hospital of Anhui Medical University, Hefei, China Shanghai Hengrui Pharmaceutical Co., Ltd., 279 Wenjing Road, Shanghai 200245, China 2Department of Immunology, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing, P.R. China School of Pharmaceutical Sciences and Tsinghua-Peking Joint Centers for Life Science; Tsinghua University; Beijing 100084; China Multi‐Organ Transplant Program University Health Network Toronto ON Canada School of Chemistry and Chemical Engineering, Southeast University, Nanjing, China Division of Nanobiomedicine and i-Lab, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123 China State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China The School of Microelectronics and Communication Engineering, Chongqing University, Chongqing 400044, China Department of Urology Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai China Department of OrthopaedicsThe First Affiliated Hospital of Guangzhou University of Traditional Chinese MedicineGuangzhouPR China State Key Laboratory of Magnetism and Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, P. R. China; School of Physical Sciences, University of Chinese Academy of Sciences, Beijing 100049, P. R. China Ajmera Transplant Centre, University Health Network , Toronto, Ontario , Canada Department of Plastic Surgery, Foshan Sanshui District People's Hospital, Foshan City, China. Department of Interventional Radiology The Affiliated Cancer Hospital of Guizhou Medical University Guiyang China Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. hewei1968@tom.com School of Computer Science and Technology, Changchun University of Science and Technology, Changchun, Jilin 130022, China; Zhongshan Institute of Changchun University of Science and Technology, Zhongshan, China Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, PR China; Department of Neurology, The Affiliated Jiangyin People's Hospital of Southeast University Medical College, Wuxi, PR China Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, P.R. China School of Computer Science and Technology, Changchun University of Science and Technology, Changchun, Jilin 130022, China State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China Department of Oral and Maxillofacial Surgery The First Affiliated Hospital of Nanchang University Nanchang China Multi-Organ Transplant Program, University Health Network, University of Toronto, Toronto, Ontario, Canada Department of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, P.R. China Guangzhou University of Chinese Medicine, Laboratory of Orthopedics and Traumatology of Chinese Medi Department of Orthopaedics,Affiliated Hospital of Jiangsu University,Zhenjiang,Jiangsu 212001,China. 1National Laboratory of Biomacromolecules, and; 2Center for Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Department of Polymer Science and Engineering, Dalian University of Technology, Dalian, Liaoning 116023, China Department of Chemistry, Fudan University, Shanghai 200433, China Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Structural and Computational Biology and Molecular Biophysics Program, Department of Molecular and Human Genetics, Program in Developmental Biology, and The Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030 1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden;; 2Chronic Disease Research Institute, the Children’s Hospital, and; 3Department of Nutrition and Food Hygiene, and National Clinical Research Center for Child Health, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; and The Lab of Orthopaedics and Traumatology, Chinese Medicine of Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou Guangdong, 510405, P.R.China;Department of Joint Orthopaedics, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou Guangdong, 510405, P.R.China;National Chinese Medicine Key Specialist of Hip Disease, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou Guangdong, 510405, P.R.China.hw13802516062@126.com. Department of Obstetrics and Gynecology, Southwest Hospital, The Third Military Medical University, Chongqing, China Department of Chemistry, University of Rochester, Rochester, New York 14627, and Department of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803-1804 Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China Department of Critical Care Medicine, Beijing Tongren Hospital, Capital Medical University Beijing, China. Department of Biology, DePauw University, Greencastle, Indiana (TM, AM, JQ, DSL, OS, WH, PJL); Division of Cardiology, Department of Medicine, Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts (JMG-R, GCB, CEB); College of Optometry, University of Houston, Houston, Texas (ARB) State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China Department of Immunology, CAMS Key Laboratory for T Cell and Immunotherapy, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing 100005, China Department of Meridians, Institute of Acupuncture and Moxibustion, Academy of Chinese Medical Sciences, 16 Nanxiaojie, Dongzhimennei, Beijing 100700, China 11Biostatistics Department, Novartis Pharmaceuticals, East Hanover, New Jersey. The First Affiliated Hospital of Jinan University, Guangzhou, China; Medical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, China Department of Medical Ultrasonics The First Affiliated Hospital of Sun Yat‐Sen University Guangzhou China Department of Orthopaedics Surgery First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine Guangzhou China Department of Biomedical Engineering, He University, ShenYang, China (mainland). Vitae Pharmaceuticals, 502 West Office Center Drive, Fort Washington, Pennsylvania 19034, United States Department of Obstetrics and Gynecology, Southwest Hospital, Third Military Medical University, Chongqing 400038, P.R. China School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China Department of Respiratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China. College of Sericulture, Textile and Biomass Sciences Southwest University Chongqing China Department of Forensic Science , School of Basic Medical Sciences, , Changsha , China; Central South University , School of Basic Medical Sciences, , Changsha , China AbbVie Inc., North Chicago, Illinois. Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing, China. State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine; Department of Liver Surgery, Sun Yat-Sen University Cancer Center, Guangzhou Institutes of Biology and Medical Sciences, Soochow University, Suzhou 215123, China; Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou 215123, China Baise University 2 College of Information Engineering, , Baise 533000, People’s Republic of China The Hormel Institute, University of Minnesota, Austin, MN 55912;; China-US (Henan) Hormel Cancer Institute, Zhengzhou 450008, China; Resgreen Group International Inc, Changsha, PR China He Eye Specialist Hospital, Shenyang, China; He University, Shenyang, China. Department of Mechanical, Aerospace and Biomedical Engineering, University of Tennessee, Knoxville, Tennessee 37996, United States; Department of Materials Science and Engineering, University of Tennessee, Knoxville, Tennessee 37996, United States Department of Critical Care Medicine, Beijing Tongren Hospital, Beijing 100730, China. Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China. hewei1968@tom.com Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16 Nanxiaojie Street, Dongzhimen Nei, Beijing 100700, China Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine Sun Yat‐Sen University Cancer Center Sun Yat‐Sen University Guangzhou P. R. China; Department of Liver Surgery Sun Yat‐Sen University Cancer Center Sun Yat‐Sen University Guangzhou P. R. China Shenyang He Eye Specialist Hospital Shenyang China; He University Shenyang China Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China Department of Physics, University of Massachusetts, Amherst, Massachusetts 01003, United States Key Laboratory of the Ministry of Education for Optoelectronic Measurement Technology and Instrument, Beijing Information Science and Technology University 2 , Beijing 100192, China; Beijing Laboratory of Optical Fiber Sensing and System, Beijing Information Science and Technology University 3 , Beijing 100016, China Cyrus Tang Hematology Center Collaborative Innovation Center of Hematology Soochow University Suzhou China; National Clinical Research Center for Hematologic Diseases the First Affiliated Hospital of Soochow University Suzhou China; State Key Laboratory of Radiation Medicine and Protection Soochow University Suzhou China School of Public Health and Management, Chongqing Medical University, Chongqing, China Department of Ultrasound, The First Hospital Affiliated to Sun Yat-sen University, Guangzhou, Guangdong 510080, China. Intensive Care Unit, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China. Department of Urology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. Department of Psychology, Institute of Acu-moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China. hewei7811@gmail.com Department of Dermatology The Children's Hospital of Fudan University Shanghai China State Key Laboratory of Fine Chemicals, Dalian University of Technology , Dalian, Liaoning 116023, China and , Dalian, Liaoning 116023, China; Department of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology , Dalian, Liaoning 116023, China and , Dalian, Liaoning 116023, China Department of Materials Science and Engineering; University of Tennessee; Knoxville; USA; Department of Mechanical Department of Urology Ruijin Hospital Shanghai Jiaotong University, School of Medicine China Department of Anesthesiology The Second Affiliated Hospital, Zhejiang University School of Medicine Hangzhou China School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 Center for Brain‐Inspired Computing Research (CBICR) Optical Memory National Engineering Research Center Beijing Innovation Centre for Future Chip Department of Precision Instrument Tsinghua University Beijing 100084 China Department of Orthopaedics Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine) Shaoxing Zhejiang China Department of Obstetrics and Gynecology, Chengdu Women’s and Children’s Central Hospital, Chengdu, China State Key Laboratory Cultivation Base for Modern Chinese Medicine, Tianjin, China. National Key Discipline and Orthopedic Laboratory Guangzhou University of Chinese Medicine Guangzhou Guangdong China; Orthopedic Department The First Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou Guangdong China Department of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China (mainland) Zhongzhi International Institute of Agricultural Biosciences, Biology and Agriculture Research Center of USTB University of Science and Technology Beijing (USTB) Beijing China Department of Hematology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, Zhejiang, People’s Republic of China School of Pharmacy, China Pharmaceutical University, Nanjing, China. weihe@cpu.edu.cn. Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China Key Laboratory of Resource Biology and Biotechnology in Western China, School of Life Science, Northwest University, Xi'an 710069, China *Department of Cell Biology and Genetics, College of Life Sciences, Peking University, Beijing, China; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine Sun Yat‐Sen University Cancer Center Guangzhou 510030 China; Department of Liver Surgery Sun Yat‐Sen University Cancer Center Guangzhou 510030 China Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030 College of Life Science, Northwest University, Xi’an, Shaanxi, China; Key Laboratory of Resource Biology and Biotechnology in Western China, Northwest University, Xi’an, Shaanxi, China Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden; Chronic Disease Research Institute the Children's Hospital, and National Clinical Research Center for Child Health School of Public Health School of Medicine Zhejiang University Hangzhou China; Department of Nutrition and Food Hygiene School of Public Health Zhejiang University Hangzhou China Division of Physical Biology and Bioimaging Center Shanghai Synchrotron Radiation Facility Shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai China; University of Chinese Academy of Sciences Beijing China State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, 200433, Shanghai, China College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu, 610065, China Department of Endocrinology and Metabolism, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China Department of Chemistry; School of Pharmacy; Fourth Military Medical University; Xi'an 710032; P. R. China MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, Jiangsu Engineering Laboratory of Animal Immunology, Institute of Immunology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China Sichuan Academy of Agricultural Sciences Crop Research Institute, , Chengdu 610066, China College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, 30 Puzhu Road South, Nanjing 211816, P. R. China Department of Pathology, Renji Hospital, School of Medicine Shanghai Jiao Tong University Shanghai China Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center , Houston , TX 77030 , USA Orthopedics Department, First Affiliated Hospital Guangzhou University of Chinese Medicine, State Key Orthopedic Laboratory of Chinese Medicine 16, Jichang Road, Baiyun Area Guangzhou 510405 China †National Key Laboratory of Medical Molecular Biology, Chinese Academy of Medical Sciences, Beijing 100730, People’s Republic of China; State Key Laboratory Breeding Base of Green Chemistry Synthesis Technology, Zhejiang University of Technology, Hangzhou 310032, People’s Republic of China Department of Ophthalmology, He Eye Specialist Hospital, Liaoning, Shenyang, China School of Sport Management and Recreation Guangzhou Sport University Guangzhou China National Key Facility for Gene Resources and Genetic Improvement/Key Laboratory of Crop Germplasm Utilization Ministry of Agriculture Institute of Crop Science Chinese Academy of Agricultural Science Beijing 100081 China Department of Ophthalmology, He Eye Specialist Hospital, Shenyang, China. Department of Physiology, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China Key Laboratory of AIDS Immunology of National Health and Family Planning Commission, Department of Laboratory Medicine, The First Affiliated Hospital, China Medical University, Shenyang, People's Republic of China. School of Nursing, Queensland University of Technology, Brisbane, Australia Second Clinical Medical College of Lanzhou University, Lanzhou, China The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405 Guangdong Province, China Institute of Materia Medica, Guangdong College of Pharmacy, Guangzhou 510006, China. weih8201@163.com Department of Urology Tongji Medical School Tongji Hospital Huazhong University of Science and Technology Wuhan China; Hubei Institute of Urology Wuhan China School of Basic Medical Sciences Anhui Medical University Hefei China Department of Pathology, Renji Hospital, Shanghai Jiaotong University School of Medicine Shanghai 200135, People's Republic of China. Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian, Liaoning 116023, P. R. China, and The Department of Chemistry, Dalian University of Technology, Dalian, Liaoning 116024, P. R. China College of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu, Sichuan 610500, P. R. China Department of Radiology, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China. Center of Orthognathic Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China. Physical and Life Sciences Division, Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, California 94550, United States Department of Medicine Geno Biotech Co Ltd Shanghai China Ruhr-University of Bochum 1 Junior Research Group Magnetic Microscopy, Institute for Experimental Physics IV, , Universitätsstr. 150, D-44780 Bochum, Germany Electric Power Research Institute of State Grid Gansu Electric Power Company, China Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700. State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, China. myway@njnu.edu.cn College of Materials Science and Engineering Huaqiao University, Key Laboratory of Molecular Designing and Green Conversions (Fujian University) Xiamen China Department of Hematology, Jinhua Municipal Central Hospital, Jinhua, Zhejiang 321000, P.R.�China Clinical Research Center for Geriatric Diseases Xiangya Hospital Changsha Hunan Province P.R. China Department of Chemistry Tsinghua University Beijing 100084 China; School of Pharmaceutical Sciences Tsinghua University Beijing 100084 China State Key Laboratory of Oral Diseases, Siehuan University, Chengdu 610041, China. Cancer Research Institute, Central South University, Changsha, Hunan, China; Xi'an Children's Hospital, Xi'an, Shaanxi, China Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China; Department of Urology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China Department of Critical Care Medicine, Beijing Tongren Hospital, Capital Medical College, Beijing 100730, China. Fabrice André, Institut Gustav Roussy, INSERM Unit U981, Université Paris Sud, Villejuif, France; Sara Hurvitz and Dennis Slamon, University of California, Los Angeles, Los Angeles, CA; Angelica Fasolo, San Raffaele Scientific Institute, Milan, Italy; Ling-Ming Tseng, National Yang Ming University, Taipei, Taiwan; Guy Jerusalem, University of Liège, Liege, Belgium; Sharon Wilks, Cancer Care Center of South Texas, San Antonio, TX; Ruth O’Regan, University of Wisconsin Carbone Cancer Center, Madison, WI;... The Second Affiliated Hospital of Kunming Medical University , Kunming, China Department of Joint Orthopaedic The First Affiliated Hospital Guangzhou University of Chinese Medicine Guangzhou China; The Lab of Orthopaedics of Chinese Medicine Lingnan Medical Research Center Guangzhou University of Chinese Medicine Guangzhou China; The First Clinical Medical College Guangzhou University of Chinese Medicine Guangzhou China; Jinshazhou Hospital Guangzhou University of Chinese Medicine Guangzhou China Ministry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Hubei Clinical Center and Key Laboratory of Intestinal and Colorectal Disease, Department of Gastroenterology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China Department of Obstetrics and Gynecology Center for Reproductive Medicine Southwest Hospital Chongqing China Jinling Hospital; Department of Orthopaedics; State Key Laboratory of Pharmaceutical Biotechnology; Nanjing University; Nanjing, China; School of Medicine and School of Life Science; Nanjing University; Nanjing, China Department of Pulmonary and Critical Care Medicine Shanghai Fifth People’s Hospital Fudan University Shanghai China State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; Savaid Medical School, University of Chinese Academy of Sciences, Beijing 100049, China College of Biotechnology and Pharmaceutical Engineering Nanjing Tech University; Nanjing; China Department of Hand Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China (mainland) MOE Laboratory for Earth Surface Processes, College of Urban & Environmental Sciences, Peking University, Beijing 100871, China Endocrinology Department, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, P.R. China School of Safety Science and Engineering, Anhui University of Science and Technology, Huainan 232001, P. R. China Science and Technology on Combustion, Internal Flow and Thermo-structure Laboratory, Northwestern Polytechnical University, Xi’an 710072, China Engineering Product Development Singapore University of Technology and Design (SUTD) 8 Somapah Road 487372 Singapore MOE Joint International Research Laboratory of Animal Health and Food Safety, Jiangsu Engineering Laboratory of Animal Immunology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China Grassland Research Institute, Chongqing Academy of Animal Science, Chongqing 402460, China Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, China Lawrence Livermore National Laboratory, Livermore, California, United States From the Shenyang He Eye Hospital, Shenyang, China; College of Biology, State Key Laboratory of Chemo/Biosensing and Chemometrics, and Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan University , Changsha , P. R. China; National Engineering Laboratory for Rice and By-product Deep Processing, Central South University of Forestry and Technology , Changsha , P. R. China College of Animal Sciences, Jilin University, Changchun, China Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China; Department of General Surgery, The Fourth Affiliated Hospital of Anhui Medical University, Hefei, China Department of Materials Science and Engineering, University of Tennessee, Knoxville, Tennessee 37996, United States State Key Laboratory of Crop Stress Biology in Arid Areas and College of Agronomy, Northwest A&F University, Xianyang 712100, China State Key Laboratory of Fine Chemicals, Dalian University of Technology 1 , Dalian 116023, China; Department of Polymer Science & Engineering, Dalian University of Technology 3 , Dalian 116023, China Beijing National Laboratory for Condensed Matter Physics, Chinese Academy of Sciences, Beijing 100190, China The Key Laboratory for Silviculture and Conservation of Ministry of Education Beijing Forestry University Beijing 100083 China Department of Thoracic Surgery, Beijing Chao-Yang Hospital, Beijing 100020, China. International Medical Center of The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou Mingzhou Hospital Hangzhou People's Republic of China Sichuan Academy of Forestry, Chengdu, P. R. China Department of Pediatrics, The Third Xiangya Hospital of Central South University, Changsha, China Department of Chemistry; School of Pharmacy; Fourth Military Medical University; Xi'an 710032, P. R. China School of Engineering and Applied Sciences Harvard University Cambridge Massachusetts USA; Wyss Institute of Biologically Inspired Engineering Boston Massachusetts USA College of Materials Science and Engineering, College of Electronics and Information Engineering, Guangdong Research Center for Interfacial Engineering of Functional Materials, Shenzhen University, 3688 Nanhai Avenue, Shenzhen 518060, People Republic of China Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China John A. Paulson School of Engineering and Applied Sciences Harvard University Cambridge MA 02138 USA Department of Medical Epidemiology and Biostatistics; Karolinska Institutet; Stockholm Sweden At the time of the study, Wei He, Sherman A. James, and M. Giovanna Merli were with the Sanford School of Public Policy, Duke University, Durham, NC. Hui Zheng is with the Department of Sociology, The Ohio State University, Columbus. Department of Psychology University of Nebraska‐Lincoln Lincoln NE USA Department of Orthopaedics, The First Affiliated Hospital of Soochow University Soochow University Suzhou China Guangdong Research Institute for Orthopedics and Traumatology of Chinese Medicine , No. 261, Longxi Road, Liwan District, Guangzhou 510378, P.R. China; Joint Center, The Third Affiliated Hospital, Guangzhou University of Chinese Medicine , No. 261, Longxi Road, Liwan District, Guangzhou 510378, P.R. China Department of Ultrasound,Third Xiangya Hospital of Central South University,Changsha 410013, China. Department of Pathology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China Department of Hepatology, Tumor Hospital, Sun Yat-sen University, Guangzhou 510060, China. yuanyf@mail.sysu.edu.cn. The Second Hospital of Lanzhou University, Lanzhou University, Lanzhou, 730000 Gansu, China; The Second Clinical Medical College of Lanzhou University, Lanzhou University, Lanzhou, 730000 Gansu, China Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China Department of Chemistry Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong China; HKUST Shenzhen Research Institute No. 9 Yuexing 1st RD, South Area Hi‐tech Park, Nanshan Shenzhen 518057 China Institute of Animal Nutrition, Northeast Agricultural University, Harbin 150030, PR China Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. Jiangsu Province Engineering Research Center for Marine Bio-resources Sustainable Utilization & College of Oceanography, Hohai University, Nanjing, PR China Department of Pharmacy, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China. College of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai 200030, China. First Affiliated Hospital Guangzhou University of Chinese Medicine 16 Jichang Road Guangzhou 510405 People's Republic of China Department of Cardiothoracic Surgery, Zhongda Hospital, Medical School, Southeast University State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Institute of Applied Ecology Fujian Agriculture and Forestry University Fuzhou China MOE Key Laboratory of Bioinorganic and Synthetic Chemistry; School of Chemistry; Sun Yat-Sen University; Guangzhou 510275; P.R. China Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA. Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry & Materials Science, Jiangsu Normal University, Xuzhou, 221116, China College of Chemistry and Molecular Science, Hubei Key Laboratory of Electrochemical Power Sources, Wuhan University, Wuhan 430072, China The Second Clinical College, Dalian Medical University, Dalian, P.R. China; Clinical Research Center, He Eye Specialists Hospitals, Shenyang, P.R. China Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China; HKUST-Shenzhen Research Institute, South Area Hi-Tech Park, Nanshan, Shenzhen 518057, China State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, People’s Republic of China. Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Division of Life Science and State Key Laboratory of Molecular Neuroscience, Institute of Molecular Functional Materials, Department Chemical and Biological Engineering and Institute for Advanced Study, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon 999077, Hong Kong, China AML Department of Engineering Mechanics Tsinghua University Beijing China Sichuan International Travel Health Care Center (Chengdu Customs Port Clinic), China Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China Institute of Acupuncture & moxibustion, China Academy of TCM, Beijing 100700, China. fion.he@sohu.com University of Science and Technology of China Hefei National Laboratory for Physical Sciences at Microscale, , Hefei, Anhui 230026, People’s Republic of China Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, China Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China Department of Meridians, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, No. 16 Nanxiaojie, Dongzhimen, Beijing 100700, China; Stronach Research Unit for Complementary and Integrative Laser Medicine, Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine, TCM Research Center Graz, Medical University of Graz, Auenbruggerplatz 29, 8036 Graz, Austria Research Institute, The Hospital for Sick Children, Toronto; and Departments of Traumatology and Orthopedics Institute, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510405, China; Department of Orthopedic, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510405, China Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences University of Science and Technology of China Anhui China Department of Radiology, Peking University Third Hospital, Beijing, China School of Materials Science and Engineering, University of Science and Technology, Beijing, China.; Suzhou Xiangcheng Medical Materials Science and Technology Co., Ltd., Suzhou, China. Key Laboratory for Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Sun Yat‐Sen University Cancer Center 651 Dongfeng Road East Guangzhou 510060 China; Department of Hepatobiliary Oncology Sun Yat‐Sen University Cancer Center Guangzhou 510060 China State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops Fujian Agriculture and Forestry University Fuzhou China; State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant Protection, Chinese Academy of Agricultural Sciences Beijing China Jiliang Qiu, Muyan Cai, Wei He, Yun Zheng, Dan Xie, Binkui Li, and Yunfei Yuan, Sun Yat-sen University Cancer Center; Baogang Peng, Junhang Luo, Bin Chen, and Zunfu Ke, First Affiliated Hospital of Sun Yat-sen University; Pi Guo and Mengfeng Li, Sun Yat-sen University; Jiliang Qiu, Muyan Cai, Wei He, Yun Zheng, Dan Xie, Binkui Li, and Yunfei Yuan, State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine; Jiliang Qiu, Yunqiang Tang, and Hui Tang, Guangzhou... State Key Laboratory of Oncology in South China Sun Yat‐Sen University Cancer Center Guangzhou China; Department of Hepatobiliary Oncology Sun Yat‐Sen University Cancer Center Guangzhou China Department of Mechanical and Industrial Engineering, Ryerson University, 350 Victoria Street, Toronto, ON M5B 2K3, Canada Institute of Medical Informatics, China Academy of Chinese Medical Sciences, Beijing 100700, China. Hewei55@hotmail.com Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine University of Rochester Medical Center Rochester New York State Key Laboratory of Biocatalysis and Enzyme Engineering Hubei Collaborative Innovation Center for Green Transformation of Bio‐Resources Hubei Key Laboratory of Industrial Biotechnology School of Life Sciences Hubei University Wuhan Hubei 430062 China Department of Chemistry & Institute of Material Science, University of Connecticut, Storrs, Connecticut 06269 State Key Laboratory of Magnetism and Beijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Beijing 100190 China Department of Ultrasonography, Third Xiangya Hospital, Central South University, Changsha 410013, China. College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University Program in Genetics, Bioinformatics, and Computational Biology, VT BIOTRANS, Virginia Tech, Blacksburg, VA, USA. hwei9@vt.edu. Division of General Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts. Department of Biochemistry, Beijing Institute of Radiation Medicine, Beijing 100850, China Collaborative Innovation Center for Nanomaterial Science and Engineering, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China Department of Intensive Care Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing, China Department of Anaesthesiology & Critical Care Medicine, Translational Neuroscience Center, West China Brain Research Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China Hubei Key Lab. of Electrochemical Power Sources, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China School of Chemistry and Chemical Engineering, Southeast University, Nanjing, Jiangsu 211189, P. R. China Food Laboratory of Zhongyuan, Beijing Technology and Business University, Beijing 100048, China; Key Laboratory of Flavor Science of China General Chamber of Commerce, Beijing Technology and Business University, Beijing 100048, China School of Materials and Energy, University of Electronic Science and Technology of China, Chengdu 610054, China Department of Applied Chemistry, School of Science, and Department of Chemical Engineering, School of Energy and Power Engineering, Xi’an Jiaotong University, Xi’an 710049, People’s Republic of China Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 999077, China; HKUST-Shenzhen Research Institute, No. 9 Yuexing First RD, South Area, Hi-Tech Park Nanshan, Shenzhen 518057, China 11Novartis Institutes for Biomedical Research, Cambridge, Massachusetts. Division of General Internal Medicine, Massachusetts General Hospital Wei He, Fang Fang, Mikael Eriksson, Per Hall, Kamila Czene, Karolinska Institutet, Stockholm, Sweden; and Catherine Varnum, School of Medicine, University of Maryland, Baltimore, MD. School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China College of Biotechnology and Pharmaceutical Engineering Nanjing Tech University 30 Puzhu Rd S. Nanjing 211816 P. R. China From the Multi Organ Transplant Program, University Health Network (M.M., M.L., A.G., W.H., C.K., I.S., M.J., J.T., W.C., L.F., S.S., P.M., T.K.W., M.J.P., R.G., G.A.L., D.G.); Canadian Institutes of Health Research Group on Cellular and Molecular Mechanisms of Organ Injury (M.M., M.L., A.G., C.K., I.S., W.C., P.M., M.J.P., R.G., G.A.L.); Departments of Immunology (M.M., C.K., I.S., M.J., R.G., G.A.L.) and Surgery (A.G., T.K.W., R.G., D.G.), Faculty of Medicine, University of Toronto; Department of... Department of Thoracic Surgery, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China Beijing National Laboratory for Condensed Matter Physics and Institute of Physics; Chinese Academy of Sciences; Beijing 100190; P. R. China The National Key Discipline and the Orthopedic Laboratory Guangzhou University of Chinese Medicine Guangzhou, Guangdong People's Republic of China; Department of Orthopedics First Affiliated Hospital Guangzhou University of Chinese Medicine Guangzhou, Guangdong People's Republic of China College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, PR China Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing, 100084 People's Republic of China; School of Medicine, Tsinghua University, Beijing 100084 People's Republic of China Department of Materials Science and Engineering The University of Tennessee Knoxville Tennessee 37996‐2100; Department of Mechanical Aerospace and Biomedical Engineering The University of Tennessee Knoxville Tennessee 37996‐2100 College of Biotechnology and Pharmaceutical Engineering Nanjing Tech University, 30 Puzhu Rd S., Nanjing 211816, China *Cancer Biology and Genetics Program, Howard Hughes Medical Institute, and Department of Cardiothoracic Surgery Zhongda Hospital, Medical School of Southeast University Nanjing Jiangsu 210009 People's Republic of China Reproductive Medical Center Department of Obstetrics and Gynecology Southwest Hospital Third Military Medical University Chongqing China Clinical College of Zunyi Medical University, Zunyi 56300, China Harbin Normal University 1 Department of Biology , , Harbin 150080, China Department of Parasitology, College of Veterinary, Sichuan Agricultural University, Chengdu 611130, China Department of Ultrasound, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China (mainland) Institute of Medical Informatics, China Academy of Chinese Medical Sciences, Beijing 100700, China. Hewei555@hotmail.com Departments of Materials Science and Engineering and Mechanical, Aerospace, and Biomedical Engineering, The University of Tennessee, Knoxville, Tennessee 37996 He's university Shenyang China; Shenyang He Eye Specialist Hospital Shenyang China Department of Respiratory and Critical Care Medicine Central Hospital Affiliated to Shenyang Medical College Shenyang China 8Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA Shenyang Key Laboratory of High Performance Plastics Engineering, Shenyang University of Chemical Technology, Shenyang 110142, China *Beckman Research Institute, City of Hope National Medical Center, Duarte, CA 91010; Chinese Academy of Sciences Shanghai Institute of Microsystem and Information Technology, , Shanghai 200050, China Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16 Nanxiaojie, Dongzhimennei, Beijing 100700, China Department of Immunology; School of Basic Medical Sciences; Anhui Medical University; Hefei; China Key Laboratory of Oral Biomedical Engineering, Ministry of Education, Sichuan University, Chengdu 610041, China. State Key Laboratory of Power Transmission Equipment & System Security and New Technology, Chongqing University, Chongqing 400030, China Department of Ophthalmology Stanford University School of Medicine Palo Alto CA USA Department of Gastroenterology, Geriatric Hospital of Nanjing Medical University, Nanjing 210024, China Department of Cell Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 Department of Physiology and Biophysics, Howard Hughes Medical Institute, Mount Sinai School of Medicine, 1425 Madison Avenue, Box 1677, New York, NY 10029, USA. Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany ‡Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing, People’s Republic of China; MOE Laboratory for Earth Surface Process, College of Urban & Environmental Sciences, Peking University, Beijing 100871, China |
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