http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_25dc4bc4d691e3647d80f48a2aed4e3c
Outgoing Links
Predicate | Object |
---|---|
family-name | Wang Qing Wang |
name | Qing Wang |
given-name | Qing |
organization-name | From the Department of Physiology (A.A.D., L.M.D.D.), University of Melbourne, Australia; the Department of Medicine (Q.W., T.P.), University of Lausanne Medical School, Switzerland; the Department of Physiology (M.E.), University of Bern, Switzerland; and the Division of Biochemistry (S.M.R.), University of Tasmania, Australia. State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, China Donghu Experimental Station of Lake Ecosystems, State Key Laboratory of Freshwater Ecology and Biotechnology of China, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China Laboratory for Photonics and Interfaces, Institute of Chemical Sciences and Engineering, Swiss Federal Institute of Technology, CH-1015 Lausanne, Switzerland, Nanomaterials Research Centre and MacDiarmid Institute for Advanced Materials and Nanotechnology, Massey University, Palmerston North, New Zealand, and MacDiarmid Institute for Advanced Materials and Nanotechnology, Chemistry Department, University of Otago, Dunedin, New Zealand Key Laboratory of Major Diseases in Children, Ministry of Education, National Key Discipline of Pediatrics (Capital Medical University), Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, China China Agricultural University Beijing Key Laboratory of Growth and Developmental Regulation for Protected Vegetable Crops, , Beijing 100193, China State Key Laboratory of Urban and Regional Ecology, Research Center for Eco‐Environmental Sciences Chinese Academy of Sciences Beijing 100085 China; University of Chinese Academy of Sciences Beijing 100049 China Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China Key Laboratory of Arable Land Conservation (North China), Ministry of Agriculture, College of Resources and Environmental Sciences, China Agricultural University, Beijing, China Department of Traditional Chinese Medicine of Wuhan Puren Hospital, Affiliated Hospital of Wuhan University of Science and Technology, 1# Benxi Street, Qingshan District, Wuhan, Hubei, P. R. China Department of Plant Biotechnology and Bioinformatics, Faculty of Sciences, Ghent University , Ghent 9052 , Belgium; Center for Plant Systems Biology, VIB-UGent , Ghent 9052 , Belgium Expanded Program on Immunization, Chongqing Center for Disease Control and Prevention, Chongqing, China School of Science, Lanzhou University of Technology, Lanzhou 730050, China School of Materials Science and Engineering, Shenyang Jianzhu University, Shenyang 110168, China Department of Gastroenterology, Qingdao Ninth People's Hospital China. College of Information Engineering, Taiyuan University of Technology, Taiyuan 030024, P.R.China. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha, Hunan 410082, China Department of Automation, Tsinghua University , Beijing, China University of the Chinese Academy of Sciences, Beijing 100049, China Institute of Agro‐Food Science and Technology Shandong Academy of Agricultural Sciences 202, Gongye North Road Jinan 250100 PR China; Key Laboratory of Agro‐Products Processing Technology of Shandong Province 202, Gongye North Road Jinan 250100 PR China; Key Laboratory of Novel Food Resources Processing Ministry of Agriculture 202 Gongye North Road Jinan 250100 PR China School of Materials Science and Engineering; Harbin Institute of Technology; Harbin 150001; China Department of Spine Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine, Research Center of Neurobiology, Shanxi University of Chinese Medicine, Taiyuan, China State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, People’s Republic of China; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, People’s Republic of China Key Laboratory of Vegetable Postharvest Processing Ministry of Agriculture and Rural Affairs Beijing Key Laboratory of Fruits and Vegetable Storage and Processing Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (North China) of Ministry of Agriculture Key Laboratory of Urban Agriculture (North) of Ministry of Agriculture Beijing Vegetable Research Center Beijing Academy of Agriculture and Forestry Sciences Beijing China Institute of Advanced Materials; Nanjing University of Posts & Telecommunications; Nanjing 210023; P. R. China Ministry of Education Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes, College of Environment, Hohai University, Nanjing 210098, China Department of Radiology, Washington University School of Medicine, 510 S, Kingshighway Blvd, St. Louis, MO 63110, USA College of Biotechnology and Food Science, Tianjin University of Commerce Tianjin China Hubei Key Laboratory of Cell Homeostasis Frontier Science Center for Immunology and Metabolism College of Life Sciences Wuhan University Wuhan China Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University, Qingdao, China F. Hoffmann-La Roche Ltd, Basel, Switzerland Department of Medical Imaging Jinling Hospital School of Medicine Nanjing University Nanjing 210002 Jiangsu P. R. China Department of Radiology Qi Lu Hospital of Shandong University Jinan China State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou, China and Department of Toxicology, School of Public Health Sun Yat‐sen University Guangzhou China Institute of Virology and AIDS Research, First Hospital of Jilin University, Changchun, China; Department of Respiratory Medicine, First Hospital of Jilin University, Changchun, China State Key Laboratory of Silkworm Genome Biology Southwest University Chongqing 400715 China School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China Laboratory for Microstructures, Institute of Materials, Shanghai University, Shanghai 200072, China The Education Ministry Key Lab of Resource Chemistry Joint International Research Laboratory of Resource Chemistry of Ministry of Education Shanghai Key Laboratory of Rare Earth Functional Materials and Shanghai Frontiers Science Center of Biomimetic Catalysis Shanghai Normal University Shanghai 200234 P. R. China School of Basic Medicine, Peking Union Medical College, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100005, China Service of Nephrology and Hypertension, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland;; Huazhong University of Science and Technology, Wuhan, China State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, China; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine/Research Center of Neurobiology, Shanxi University of Chinese Medicine, Taiyuan, China Department of Materials Science and Engineering, Faculty of Engineering, National University of Singapore, Singapore 117576 Institute of Rocket Force Medicine State Key Laboratory of Trauma, Burns and Combined Injury Third Military Medical University Chongqing China Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03755. School of Environmental and Chemical Engineering Jiangsu University of Science and Technology Zhenjiang Jiangsu 212003 China State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio‐Nanotechnology and Molecular Engineering of Hunan Province Hunan University Changsha 410082 China School of Materials Science and Engineering, Northeastern University, 110819, Shenyang, China; School of Resources and Materials, Northeastern University at Qinhuangdao, Qinhuangdao, 066004, China; Key Laboratory of Dielectric and Electrolyte Functional Material Hebei Province, Qinhuangdao, 066004, China Department of Orthopedics The First Affiliated Hospital of Nanjing Medical University 300 Guang Zhou Road Nanjing 210029 China Department of Hematology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China Henan University People’s Hospital, Henan Provincial People’s Hospital, Henan Eye Hospital, Henan Eye Institute, Zhengzhou, China Department of Obstetrics and Gynecology, First Affiliated Hospital, Xi’an Jiaotong University, Xi’an, China Department of Cardiothoracic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China Key Laboratory of Structure‐Based Drug Design and Discovery Ministry of Education Shenyang Pharmaceutical University Shenyang China Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, Department of Preventive Medicine, Medical School Hunan Normal University Changsha China Department of Neurology and State Key Laboratory of Biotherapy National Clinical Research Center for Geriatrics West China Hospital Sichuan University Chengdu 610041 China Rehabilitation Engineering Centre, The Hong Kong Polytechnic University, China Department of Chemistry, Nagoya University, Nagoya 464-8602, Japan Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao 266001, China School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, People’s Republic of China State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, P. R. China Department of Medical Engineering, Xinqiao Hospital, Third Military Medical University, Chongqing, China Department of Materials Science and Engineering, Faculty of Engineering, NUSNNI-NanoCore, National University of Singapore, Singapore 117576, Singapore MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China State Key Laboratories for Agro-Biotechnology, China Agricultural University, Beijing, People's Republic of China; College of Agriculture and Biotechnology, China Agricultural University, Beijing, People's Republic of China; France-China Biomineralization and Nanostructure Laboratory, Beijing, People's Republic of China Department of Computer Sciences, Mathematics, and Engineering, Shepherd University, Shepherdstown, WV 25433, USA *Department of Respiratory Diseases, First Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310003 Zhejiang, China; Department of Materials Science and Engineering, NUSNNI-NanoCore, National University of Singapore, 9 Engineering Drive 1, Singapore, 117576 Institute for Catalysis, Hokkaido University, Kita 21-10, Sapporo 001-0021, Japan Department of Anesthesiology, Guangdong General Hospital/Guangdong Academy of Medical Sciences, Guangzhou 510080, China. wqzly@ hotmail.com Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural University, Guangzhou, China; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China Department of Obstetrics and Gynecology, First Affiliated Hospital, Xi’an Jiaotong University, Xi’an Shaanxi, China Department of Neurosurgery The Second Affiliated Hospital of Soochow University Suzhou Jiangsu P.R. China State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences Sun Yat‐Sen University Guangzhou China; College of Marine Sciences South China Agricultural University Guangzhou China State Key Laboratory of Plant Genomics and National Plant Gene Research Center, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China (J.M., J.B., F.F., F.A., J.Zh., H.J., Q.W., J.Zu.); and Department of Neurology, The Affiliated ZhongDa Hospital, School of Medicine, Institution of Neuropsychiatry, Southeast University, Nanjing, China Department of Orthopedics The first Affiliated Hospital of Soochow University Suzhou China Key Discipline Open Laboratory of Animal Viral Disease Control and Residual Analysis of Henan Province, Department of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang, China Neuro Data Science-ORIGAMI Laboratory, McConnell Brain Imaging Centre, McGill University, Montreal, QC, Canada Shaanxi University of Chinese Medicine Xianyang P. R. China *State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, People's Republic of China; Department of Biology and Chemistry, Indiana University, Bloomington, Indiana 47401. School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, China State Key Laboratory of Oncogenes and Related Genes Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China Faculty of Chemistry, Biotechnology and Food Sciences, Norwegian University of Life Sciences, Ås, Norway School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine Guangzhou 510006 P.R. China Key Laboratory of Photochemical Conversion and Optoelectronic Materials; Technical Institute of Physics and Chemistry; Chinese Academy of Sciences; Beijing, P. R. China; University of Chinese Academy of Sciences Department of Radiology, First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Rd, Nanjing, China, 210000. Department of Materials Science and Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802, College of Polymer Science and Engineering, Sichuan University, Chengdu 610065, P. R. China, and Polymics Ltd., State College, Pennsylvania 16803 Department of Endocrinology, China‑Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China Laboratory for Microstructures, Institute of Materials Science, Shanghai University, Shanghai 200072, China From the Rammelkamp Center for Research (R.D., A.M.B., G.E.K.), MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio; the Howard Hughes Medical Institute (Q.W., M.T.K.), University of Utah Health Sciences Center, Salt Lake City; the Department of Molecular Physiology and Biophysics (H.A.H.), Baylor College of Medicine, Houston, Tex; and the Department of Cardiology (P.J.S.), University of Pavia (Italy). Engineering Research Centre of Oil Shale Comprehensive Utilization, Ministry of Education, Northeast Electric Power University, Jilin City, Jilin 132012, China Department of Neonatology, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, Chongqing Key Laboratory of Pediatrics, Children's Hospital of Chongqing Medical University, Chongqing 400014, China. Service of Nephrology and Hypertension, Centre Hospitalier Universitaire Vaudois, Lausanne;; Huazhong University of Science and Technology, Wuhan, China Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin 300121, P.R. China Mechanical Engineering and Materials Science, Washington University, St. Louis, Missouri. Division of Nephrology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University , Changsha 410082, China Nanjing University of Chinese Medicine Nanjing 210023, China Jangsu Kanion Pharmaceutical Co., Ltd. Lianyungang 222001, China. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of General and Emergency Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China. National Engineering Research Center for Biomaterials; Sichuan University; Chengdu 610064; China School of Nursing Nanjing University of Chinese Medicine Nanjing Jiangsu People's Republic of China Department of Rheumatology and Autoimmunology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Key Laboratory of Rheumatic Disease and Translational medicine, Shandong medicine and Health Key Laboratory of Rheumatism. Laboratory of Veterinary Mycoplasmology College of Veterinary Medicine Southwest University Chongqing China Fujian Key Laboratory of Integrative Medicine on Geriatric Academy of Integrative Medicine Fujian University of Traditional Chinese Medicine Fujian China Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030 Hubei, P. R. China Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedics Institute, Medical College, Soochow University , Suzhou, Jiangsu 215006 , China MOE Laboratory of Bioinorganic and Synthetic Chemistry, State Key Laboratory of Optoelectronic Materials and Technologies, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China, and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China From Basel Institute for Clinical Epidemiology & Biostatistics, University Hospital Basel, Basel, Switzerland; University of Siena, Siena, Italy; University College London, London, United Kingdom; Innsbruck Medical University, Innsbruck, Austria; University of Athens, Athens, Greece; Université Bordeaux, Bordeaux, France; Stichting HIV Monitoring, Amsterdam, the Netherlands; University Hospital of Cologne, Cologne, Germany; Hospital General Universitario Gregorio Marañó,; Madrid, Spain; Rigshospitalet, Copenhagen, Denmark; IRCCS Ospedale San Raffaele, Milan, Italy; National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, Italy; University of Brescia, Brescia, Italy; University of Modena and Reggio Emilia, Modena, Italy; University of Barcelona, Barcelona, Spain; Centre Hospitalier Universitaire Saint-Pierre, Brussels, Belgium; and University Hospital Zurich and University of Zurich, Zurich, Switzerland. State Key Laboratory for Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing 210095, P.R. China; Jiangsu Collaborative Innovation Center for Modern Crop Production, Nanjing Agricultural University, Nanjing 210095, P.R. China; College of Agriculture, Nanjing Agricultural University, Nanjing 210095, P.R. China Key Laboratory of Fishery Drug Development of Ministry of Agriculture, Key Laboratory of Aquatic Animal Immune Technology of Guangdong Province, Pearl River Fisheries Research Institute Chinese Academy of Fishery Sciences Guangzhou China Department of Materials Science and Engineering The Pennsylvania State University University Park PA 16802 USA Xingrong Renewable Energy Co., Ltd, Chengdu, People’s Republic of China Key Lab of Animal Bacteriology, Ministry of Agriculture, Nanjing Agricultural University, Nanjing 210095, China. Shaanxi Key Laboratory of Space Materials Science and Technology School of Physical Science and Technology Northwestern Polytechnical University Xi'an 710072 China Shaanxi Engineering Research Centre for Conservation and Utilization of Botanical Resources, Xi’an Botanical Garden of Shaanxi Province (Institute of Botany of Shaanxi Province), Xi’an 710061, China State Key Laboratory of Systematic and Evolutionary Botany Institute of Botany Chinese Academy of Sciences Beijing 100093 China; Beijing Radiation Center Beijing 100875 China; College of Life Sciences Liaoning Normal University Dalian 116029 China College of Law and Political Science Zhejiang Normal University Jinhua China School of Biomedical Informatics Key Laboratory of Fishery Drug Development of Ministry of Agriculture Key Laboratory of Aquatic Animal Immune Technology of Guangdong Province Pearl River Fisheries Research Institute Chinese Academy of Fishery Sciences Guangzhou China Department of Neurology, Affiliated ZhongDa Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China Department of Translational Research, Centre Leon Berard, 69008 Lyon France Department of Clinical Laboratory, Affiliated Hospital of Qingdao University, China Department of General Surgery, The Second Affiliated Hospital, The Air Force Military Medical University, Xi’an, Shaanxi 710038, China State Key Laboratory of Chemo/Biosensing and Chemometrics; College of Chemistry and Chemical Engineering; College of Biology; Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province; Hunan University College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, P. R. China 5Research Institute of Information and Technology, Tsinghua University, Beijing, China Zhujiang Hospital of Southern Medical University, Department of Neurology, Guangzhou, Guangdong Province, China. Department of stomatology, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China School of Materials Science and Engineering Northeastern University Shenyang 110819 P. R. China; School of Resources and Materials Northeastern University at Qinhuangdao Qinhuangdao 066004 P. R. China; Key Laboratory of Dielectric and Electrolyte Functional Material Hebei Province Qinhuangdao 066004 P. R. China Department of Imaging The People's Hospital of Zhangqiu Area Jinan China National Center for Liver Cancer The Naval Medical University Shanghai China State Key Laboratory of Urban and Regional Ecology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; Guangdong Key Laboratory of Sugarcane Improvement and Biorefinery, Guangdong Provincial Bioengineering Institute (Guangzhou Sugarcane Industry Research Institute), Guangzhou 510316, China Molecular Cardiology, and College of Marine Sciences, South China Agricultural University, Guangzhou 510642, China Department of Gastroenterology, Qilu Hospital of Shandong University, Qingdao, Shandong, China State Key Laboratories for Agrobiotechnology and College of Biological Sciences, China Agricultural University, Beijing, China; France-China Bio-Mineralization and Nano-Structure Laboratory, Beijing, China Department of Pathology and Pathophysiology, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, Yunnan 650500, P.R. China State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350002, China Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China "2011" Collaborative Innovation Center/Research Center of Neurobiology, Shanxi University of Chinese Medicine, Taiyuan, China Basic Medical College, Shanxi University of Chinese Medicine, Jinzhong, China Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029, China Department of Ophthalmology, the Affiliated Hospital of Medical College, Qingdao University, Qingdao, China. Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, U.S.A. Tea Research Institute, Guangdong Academy of Agricultural Sciences Guangdong Key Laboratory of Tea Plant Resources Innovation & Utilization Guangzhou China Department of Biological, Geological, and Environmental Sciences, Cleveland State University, Cleveland 44115; Center for Molecular Genetics, Cleveland Clinic Foundation, Cleveland, Ohio 44195; Department of Molecular Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio 44195; Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195 Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, College of Chemistry and Life Sciences, Zhejiang Normal University, 688 Yingbin Road, Jinhua 321004, China Master of Nursing, Assistant to the Director of the Nursing Department, Nursing Department, Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School Jiangsu China School of Resources and Materials, Northeastern University at Qinhuangdao, Qinhuangdao 066004, PR China; Key Laboratory of Dielectric and Electrolyte Functional Material Hebei Province, Qinhuangdao 066004, PR China; School of Materials Science and Engineering, Northeastern University, Shenyang 110819, PR China NUSNNI-Nanocore, National University of Singapore, Singapore 117576; Department of Materials Science and Engineering, National University of Singapore, Singapore 117576 Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China School of Nursing, Nanjing University of Chinese Medicine Departments of Molecular Cardiology and of Cardiology, Center for Molecular Genetics, The Cleveland Clinic Foundation, Cleveland, Ohio 44195 Hutchison MediPharma Limited, Building 4, 720 Cai Lun Road, Zhangjiang Hi-Tech Park, 201203, Shanghai, China Department of Infectious Disease, Ningxiang People’s Hospital, Hunan, China Central Sterile Supply Department, Yiwu Central Hospital, Jinhua 322000, Zhejiang, China Expanded Program on Immunization, Chongqing Center for Disease Control and Prevention, Chongqing, China. Departments of Hepatic Surgery, Second Military Medical University, Shanghai, People's Republic of China; Key Laboratory of Molecular Biophysics of Ministry of Education, Department of Genetics and Developmental Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China 3Division of Hematology-Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan. Editorial Department of West China Journal of Stomatology, Sichuan University, Chengdu 610041, China. Department of Neurosurgery, Wuxi Second Hospital Affiliated to Nanjing Medical University, Wuxi, China. Second Department of Respiratory Medicine, The First People’s Hospital of Kunming, Kunming, Yunnan Province, China Key Laboratory of Organic Synthesis of Jiangsu Province; College of Chemistry Chemical Engineering and Materials Science; Soochow University; Suzhou; China Department of Oncology and Hematology, China-Japan Union Hospital of Jilin University, Changchun, P.R. China Provincial Key Laboratory of Oil & Gas Chemical Technology, College of Chemistry & Chemical Engineering, Northeast Petroleum University, Daqing, PR China Dongguan Institue of Opto-Electronics Peking University, Dongguan 523500808, P. R. China Department of Radiology the First Affiliated Hospital with Nanjing Medical University Nanjing P.R. China Department of Gastrointestinal Surgery Zhongnan Hospital of Wuhan University Wuhan 430071 P. R. China; College of Chemistry and Molecular Sciences Wuhan University Wuhan 430072 P. R. China Rutgers—New Jersey Medical School, Newark, NJ, USA China-Japan Union Hospital, Jilin University, Changchun 130033, Jilin Province, China. Department of Hematology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, P.R. China Authors' Affiliations: 1International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute; 2Department of Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University; and 3State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P.R. China Departament de Ciències Experimentals, Universitat Jaume I, 12071 Castelló, Spain, and Laboratory for Photonics and Interfaces, Institute of Chemical Sciences and Engineering, Swiss Federal Institute of Technology, CH-1015 Lausanne, Switzerland China Center for Health Development Studies, Peking University , Peking, China. State Key Laboratory of Agricultural Genomics BGI‐Shenzhen Shenzhen China; College of Life Sciences University of Chinese Academy of Sciences Beijing China Department of Stomatology of Zhongshan Hospital, Fudan University.Shanghai 200032; China. wang.qing@zs-hospital.sh.cn School of Material Science and Engineering; Shandong University of Science and Technology; Qingdao 266590; P. R. China State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Guangdong Provincial Engineering Technology Research Center for Healthy Breeding of Important Economic Fish, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China; College of Marine Sciences, South China Agricultural University, Guangzhou, People's Republic of China Department of Mechanical Engineering City University of Hong Kong Hong Kong China; Laboratory for Microstructures Institute of Materials Science Shanghai University Shanghai 200072 China School of Physics and Materials Science, Jiangxi Key Laboratory for Two-Dimensional Materials, Nanchang University, Nanchang 330031, P. R. China Department of Pathology and Laboratory Medicine, University Hospital, Newark, New Jersey, USA Department of Anesthesiology, Guangdong Provincial People's Hospital Guangdong Academy of Medical Sciences 510080 Guangzhou China Tianjin Key Laboratory for Photoelectric Materials and Devices; School of Materials Science & Engineering; Tianjin University of Technology; Tianjin 300384; China Innovation and Transformation Center, Collaborative Innovation Center for Rehabilitation Technology, Fujian Key Laboratory of Integrative Medicine on Geriatrics, Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine , 1 Qiuyang Road, Minhou, Fuzhou 350122 , China Madigan Army Medical Center, Tacoma, Washington Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China; Engineering Research Center of Chinese Medicine Resource, Ministry of Education, Beijing 100193, China Department of Gynecology, Pudong New District Maternal and Child Health Hospital, Shanghai, P.R. China Key Laboratory of Novel Food Resources Processing, Ministry of Agriculture and Rural Affairs/Key Laboratory of Agro-Products Processing Technology of Shandong Province/Institute of Agro-Food Science and Technology, Shandong Academy of Agricultural Sciences, Jinan, PR China School of Chinese Materia Medica; Beijing University of Chinese Medicine; Beijing P.R. China Department of Translational Research and Innovation, Centre Léon Bérard, Lyon, France Beijing Radiation Center Beijing 100875 China Shenzhen Engineering Laboratory of Microalgal Bioenergy, Harbin Institute of Technology Shenzhen, Shenzhen 518055, China Department of Obstetrics and Gynecology, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, China Department of Orthopaedics Surgery, Wuhan General Hospital of Guangzhou Command, Wuhan, China Department of Psychiatry David Geffen School of Medicine University of California Los Angeles Los Angeles CA USA Department of Nephrology, Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, Shanghai 201700, P.R. China Department of Biophysics and Structural Biology Institute of Basic Medical Sciences Chinese Academy of Medical Sciences & School of Basic Medicine Peking Union Medical College Beijing 100005 P. R. China Materials Sciences Division, Lawrence Berkeley Laboratory, University of California, 94720.; Department of Chemistry, University of California, Berkeley, CA 94720, USA. Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA From the CVPath Institute, Inc, Gaithersburg, MD (F.O., E.P., K.S., K.Y., E.L., F.D.K., R.V.); Abbott Vascular, Santa Clara, CA (L.E.L.P., J.P.L., Q.W., M.K., J.W., R.J.P.); and American Preclinical Services, Minneapolis, MN (M.F.). Department of Advanced Materials Science and Engineering Faculty of Engineering Sciences Kyushu University Kasuga Fukuoka 816–8580 Japan Institut de Pharmacologie et de Toxicologie de l’Université, Rue du Bugnon 27, CH-1005 Lausanne, Switzerland; University of North Carolina, School of Medicine, CB#7020, 724 Burnett–Womack Boulevard, Chapel Hill, NC 27599-7020; Division of Hypertension, Centre Hospitalier Universitaire Vaudois, Rue P. Decker, CH-1011 Lausanne, Switzerland; and Swiss Institute for Experimental Cancer Research, Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom Key Laboratory of Advanced Catalytic Materials and Technology, Advanced Catalysis and Green Manufacturing Collaborative Innovation Center, Changzhou University, Changzhou, Jiangsu Province 213164, China Departments of General Surgery, TangDu Hospital Xi'an China Department of Psychiatry and Semel Institute for Neuroscience and Human Behavior, The David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA Department of Materials Science and Engineering, Faculty of Engineering, NUSNNI-NanoCore, National University of Singapore, Singapore 117576 School of Resources and Environmental Engineering, State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, East China University of Science and Technology, Shanghai 200237, P. R. China “2011” Collaborative Innovation Center/Research Center of Neurobiology, Shanxi University of Traditional Chinese Medicine, Taiyuan 030619, China Department of Ophthalmology, Columbia University, New York, NY, USA; Edward S Harkness Eye Institute, Columbia University Irving Medical Center, New York, NY, USA F. Hoffmann‐La Roche Ltd Basel Switzerland Department of Obstetrics and Gynecology Third Affiliated Hospital of Soochow University Changzhou China National Engineering Research Center for Biomaterials; Sichuan University; Chengdu 610064; P. R. China Department of Neurology Affiliated ZhongDa Hospital School of Medicine Southeast University Nanjing China ICGM Université Montpellier CNRS, EMSCM Montpellier France Key Laboratory of Molecular Biophysics of the Ministry of Education College of Life Science and Technology Center for Human Genome Research Cardio‐X Institute Huazhong University of Science and Technology Wuhan China State Key Laboratory for Diagnosis and Treatment of Infectious Disease National Clinical Research Center for Infectious Diseases The First Affiliated Hospital Zhejiang University Hangzhou China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases Hangzhou China Department of Materials Science and Engineering; NUSNNI-NanoCore; National University of Singapore; , Singapore From the Division of Nephrology (Q.W., M.B.) and the Department of Medicine (A.A.D., T.P.), University Hospital, Lausanne, Switzerland. Department of Pharmacology, Ningxia Medical University, Yinchuan, China Department of Materials Science and Engineering National University of Singapore Singapore 117576 Singapore Centre Léon Bérard, Laboratory of Constitutional Genetics for Frequent Cancer HCL-CLB , 28 Laennec street, 69008 Lyon , France; Centre Léon Bérard, Lyon Cancer Research Center, Cancer Genomic Platform , 28 Laennec street, 69008 Lyon , France The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine/Research Center of Neurobiology, Shanxi University of Chinese Medicine, Taiyuan, Shanxi Province, China School of Pharmaceutical Sciences, Zhengzhou University; Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China; Key Laboratory of Henan Province for Drug Quality and Evaluation Department of Chemical & Biomolecular Engineering, Tulane University, New Orleans, Louisiana 70118 Department of Orthopedics, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China; and Department of Orthodontics, Stomatological Hospital, Southern Medical University, Guangzhou, China Department of Breast Surgery Caner Hospital of Yunnan Province The Third Affiliated Hospital of Kunming Medical University Kunming China Department of Obstetrics and Gynecology Peking University People's Hospital Beijing China; Beijing Key Laboratory of Female Pelvic Floor Disorders Beijing China School of Pharmacy, Yantai University, 264005 Yantai, PR China State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University , Xi'an, Shaanxi 710032, China Department of Materials Science and Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802, United States Department of Translational Research and Innovation Léon Bérard Cancer Centre Lyon France Nanjing University of Science and Technology State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, P. R. China Department of Oncology The First People's Hospital of Qujing Qujing Yunan P.R. China Guangzhou Key Laboratory of Environmental Health and Risk Assessment Department of Toxicology School of Public Health Sun Yat‐sen University Guangzhou China; Collaborative Innovation Center for Cancer Medicine Sun Yat‐sen University Cancer Center Guangzhou China Department of Physics, University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080 United States Department of General Surgery Tianjin Medical University General Hospital Tianjin China Beijing Key Laboratory of Growth and Developmental Regulation for Protected Vegetable Crops, College of Horticulture China Agricultural University Beijing China; Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences The University of Tokyo Tokyo Japan Department of Implantology, Shandong Provincial Key Laboratory of Oral Biomedicine, Shandong University School of Stomatology, Jinan and Department of Dentistry, Weifang People's Hospital, Weifang, Shandong, China. School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Immunization Program Office, Chongqing Center for Disease Control and Prevention Department of Respiratory and Critical Care Medicine of Kunming Municipal First People's Hospital, Kunming, Yunnan 650000, China; Graduate School, Tianjin Medical University, Tianjin 300070, China MRC Laboratory of Molecular Biology; Cambridge UK Programs in Neuroscience, Washington State University, Pullman, Washington; and State Key Laboratory of Agricultural Genomics Shenzhen China; College of Life Sciences University of Chinese Academy of Sciences Beijing China College of Life Sciences, Nankai University, Tianjin, China School of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, Shandong, People’s Republic of China Key Laboratory of Plant Functional Genomics of the Ministry of Education College of Agriculture Yangzhou University Yangzhou China Biochemistry and Molecular Biology, Ningxia Medical University, Yinchuan 750004, China Email: wang.qing@zs-hospital.sh.cn. State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute Renji Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai China School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, People’s Republic of China 4Department of Laboratory Medicine, Biomolecular and Cellular Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, SE-141 86, Huddinge, Sweden Institute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Jiangsu National Synergetic Innovation Center for Advanced Materials Nanjing Tech University Nanjing 211816 China State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China Department of Obstetrics and Gynecology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China. School of Pharmaceutical Science and Technology, Dalian University of Technology; State Key Laboratory of Fine Chemicals, Dalian University of Technology Department of Health Psychology, School of Nursing and Rehabilitation Shandong University Jinan China Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University Medical College, Qingdao 266003, China Key Laboratory of Molecular Biophysics of the Ministry of Education College of Life Science and Technology Center for Human Genome Research and Cardio‐X Institute Huazhong University of Science and Technology Wuhan China; Center for Cardiovascular Genetics Department of Molecular Cardiology Lerner Research Institute Cleveland Clinic OH USA; Department of Molecular Medicine CCLCM Cleveland OH USA; Department of Genetics and Genome Sciences Case Western Reserve University Cleveland OH USA Hebei Key Laboratory of Optic-Electronic Information and Materials, College of Physics Science and Technology, Hebei University, Baoding 071002, P. R. China Department of Radiology Qilu Hospital of Shandong University Jinan 250012 China From the Departments of Immunology (D.J.-w., C.Z.A., J.M.J., V.K.T.), Molecular Cardiology (S.Y., Q.W., D.M.P.), Anesthesiology Research (P.J.W., D.S.D.), Central Cell Services (P.C.), and Cardiovascular Medicine and Cell Biology (Z.B.P., M.S.P.), Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio. Division of Infectious Diseases,Chinese Center for Disease Control and Prevention,Beijing,China Department of Thoracic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200217, China Department of Pediatric Surgery, Huai'an Women and Children's Hospital, Jiang Su, Huai'an, China State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China Departments of Orthopaedics, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China Department of Neurosurgery The Affiliated Wuxi Second People's Hospital of Nanjing Medical University Wuxi Jiangsu China Department of Pharmacy, School of Stomatology Fourth Military Medical University Xi'an P. R. China The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Normal University, Shanghai 200234, P. R. China Key Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, PR China Immunization Program Department, Chongqing Municipal Center for Disease Control and Prevention, Chongqing, China Department of Neurosurgery, Wuxi Second Hospital Affiliated Nanjing Medical University, Wuxi 214002, China. Department of Clinical Laboratory The Second Hospital of Shandong University Jinan China; Department of Clinical Laboratory Dezhou People's Hospital Dezhou China Department of Radiology, Qilu Hospital of Shandong University, Jinan 250012, PR China State Key Laboratory for Agrobiotechnology, College of Biological Sciences China Agricultural University Beijing 100193 P. R. China; France‐China Bio‐mineralization and Nano‐structure Laboratory Beijing 100193 P. R. China Hefei National Research Center for Physical Sciences at Microscale, University of Science and Technology of China, Hefei 230026, China. Ordered Matter Science Research Center, Jiangsu Key Laboratory for Science and Applications of Molecular Ferroelectrics Southeast University Nanjing 211189 China Department of Dermatology Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China Department of Ophthalmology, The Affiliated Hospital of Qingdao University , Qingdao, Shandong 266002, China Department of Cardiology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong, China (mainland) Key Laboratory of Fishery Drug Development of Ministry of Agriculture Key Laboratory of Aquatic Animal Immune Technology of Guangdong Province Pearl River Fisheries Research Institute Chinese Academy of Fishery Sciences Guangzhou Guangdong China Institute of Hydrobiology and Key Laboratory of Aquatic Eutrophication and Control of Harmful Algal Blooms, Guangdong Higher Education Institutes, Guangzhou 510006, China Department of Implantology, Shandong Provincial Key Laboratory of Oral Biomedicine , Shandong University School of Stomatology , Jinan250012 , Shandong Province , Republic of China; Department of Dentistry , Weifang People’s Hospital , Weifang261000 , Shandong Province , People’s Republic of China Guangzhou Key Laboratory of Environmental Pollution and Health Risk Assessment, Department of Toxicology, School of Public Health, Sun Yat-sen University, Guangzhou, China; Ophthalmology, Affiliated Hospital of Qingdao University, Qingdao, People’s Republic of China Resources and Ecological Economics Research Center, Northeastern University, Shenyang 110004, China. Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266061, P.R. China Division of Hematology-Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA. Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China. Department of Hematology, Gui Zhou Provincial People's Hospital Department of Toxicology and Cancer Biology College of Medicine University of Kentucky Lexington KY USA Department of Oncology, The First People’s Hospital of Qujing/The Qujing Affiliated Hospital of Kunming Medical University, Qujing, Yunnan, China Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education); School of Environmental Science and Technology; Dalian University of Technology; Dalian 116024; P. R. China Departments ofPathology & Laboratory Medicine andObstetrics, Gynecology, and Women's Health, Rutgers-New Jersey Medical School, Newark, NJ School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, Texas, USA Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, China; Beijing Key Laboratory of Female Pelvic Floor Disorders, Beijing, China State Key Laboratory of Agricultural Genomics, BGI-Shenzhen, Shenzhen, China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China Department of Radiology Qilu Hospital of Shandong University Jinan China Department of Materials Science and Engineering, College of Design and Engineering National University of Singapore Singapore 117576 Singapore Research Institute of Petroleum Exploration and Development, Beijing, China State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, P. R. China Department of Orthopedics, Shandong Public Health Clinical Center Affiliated to Shandong University, Jinan, China 2Division of Hematology-Oncology, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, MI School of Food and Biological Engineering Jiangsu University Zhenjiang 212013 P.R. China Oncogenetics Department, Centre Léon Bérard, 69003 Lyon, France Department of Physics, The University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080, United States School of Life Science, Northeast Agricultural University, Harbin, Heilongjiang, China Key Laboratory of High-Precision Computation and Application of Quantum Field Theory of Hebei Province, College of Physics Science and Technology, Hebei University, Baoding 071002, China CAS Key Laboratory of Materials for Energy Conversion, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, P. R. China; University of Chinese Academy of Sciences, Beijing 100049, P. R. China Department of Hematology, Gui Zhou Provincial People’s Hospital, Guiyang 550002, P.R. China.; Department of Hematology, Gui Zhou Provincial People’s Hospital, Guiyang 550002, P.R. China. Department of Hepatic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China. F. Hoffmann–La Roche Ltd Basel Switzerland School of Material Science and Engineering, Institute of Nano Engineering, Shandong University of Science and Technology, Qingdao 266590, China Department of Material Science and Chemistry China University of Geosciences Wuhan 430074 P. R. China; Department of Materials Science and Engineering The Pennsylvania State University University Park Pennsylvania 16802 USA Department of Mechanical Engineering, City University of Hong Kong, Hong Kong SAR, China; Laboratory for Microstructures Institute of Materials Science, Shanghai University, Shanghai 200072, China State Key Laboratory for Biocontrol, School of Life Sciences, Sun Yat-sen (Zhongshan) University, 135 Xingang Road West, Guangzhou 510275, People's Republic of China Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China Department of Surgery Xiang'an Hospital of Xiamen University Xiamen China School of Public Health, Cheeloo Collage of Medicine, Shandong University, Jinan, China; Institute for Medical Dataology, Cheeloo Collage of Medicine, Shandong University, Jinan, China; Pudong Institute for Health Development, Shanghai, China Department of Neurosurgery, Affiliated Wuxi Second Hospital of Nanjing Medical University, Wuxi 214001, P. R. China. wxwqnj@hotmail.com Graduate School of Anhui University of Traditional Chinese Medicine, Hefei 230022, China Department of Stomatology of Zhongshan Hospital, Fudan University, Shanghai, China. College of Environmental Sciences and Engineering, Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria, Nankai University, Tianjin 300071, China State Key Laboratory of Petroleum Resources and Prospecting, China University of Petroleum, Beijing, Beijing 102249, P. R. China; Key Laboratory of Petroleum Engineering of the Ministry of Education, China University of Petroleum, Beijing, Beijing 102249, P. R. China National Engineering Research Center for Vegetables, Beijing Academy of Agriculture and Forestry Sciences Beijing Key Laboratory of Fruits and Vegetable Storage and Processing Beijing 100097 China F. Hoffmann–La Roche Ltd, Basel, Switzerland Institut de Chimie Physique, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, P.R, China 1Department of Cancer Biology and Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky. Department of Nursing, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou Province, China Institute of Agro‐Food Science and Technology, Shandong Academy of Agricultural Sciences/Key Laboratory of Agro‐Products Processing Technology of Shandong Province/Key Laboratory of Novel Food Resources Processing Ministry of Agriculture, 202 Gongye North Road Jinan 250100 China Department of Pharmacy, College of Chemistry Engineering Dalian University of Technology Dalian China; State Key Laboratory of Fine Chemicals Dalian University of Technology Dalian China Department of Hematology, Centre Hospital of Cangzhou, Cangzhou, Hebei Province, China Department of Orthopedics, the Affiliated Hospital, Southwest Medical University, Luzhou Sichuan, 646000, P. R. China. Chinese Academy of Fishery Sciences, Pearl River Fisheries Research Institute, Key Laboratory of Fishery Drug Development; Ministry of Agriculture, Key Laboratory of Aquatic Animal Immune Technology, Guangdong Province Guangzhou 510380 China EPI Department, Chongqing Municipal Center for Disease Control and Prevention, Chongqing, China Fujian Key Laboratory of Integrative Medicine on Geriatric, Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China Department of Pharmacy, School of Stomatology Fourth Military Medical University 145 West Changle Road Xi'an 710032 People's Republic of China College of Chemical Engineering Sichuan University Chengdu People's Republic of China Department of Ophthalmology Affiliated Hospital of Qingdao University Qingdao China Department of Radiology, Qilu Hospital of Shandong University, Jinan, Shandong, China Department of Nephrology, Traditional Chinese Internal Medicine e-Institute of Shanghai University, ShuGuang Hospital, Shanghai University of Traditional Chinese Medicine, PR China Nanjing Medical University, China College of Food Science and Technology Henan University of Technology Zhengzhou China Department of Rheumatology and Immunology, The Second Affiliated Hospital of Soochow University, Suzhou, China Key Laboratory of Molecular Biophysics of the Ministry of Education, Cardio‐X Institute, College of Life Science and Technology and Center of Human Genome Research Huazhong University of Science and Technology Wuhan China State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, People’s Republic of China Department of Automation, Tsinghua University, No.30 Shuangqing Road, Haidian District, Beijing, P.R. China; Pharmacovigilance Research Center for information technology and Data Science,Cross-strait Tsinghua Research Institute, NO.516 Qishan North Road, Huli District, Xiamen, P.R. China School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, P. R. China Institut de Pharmacologie et de Toxicologie, Université de Lausanne, Rue du Bugnon 27, 1005 Lausanne, Switzerland; University of North Carolina, School of Medicine, Campus Box 7020, 724 Burnett–Womack Boulevard, Chapel Hill, NC 27599-7020; Division d’Hypertension, Centre Hospitalier Universitaire Vaudois, Rue P. Decker, 1011 Lausanne, Switzerland; Department of Anatomy and Cell Biology, University of Michigan, Medical Sciences 2, Ann Arbor, MI 488109-0616; Swiss Institute for Experimental ... Department of Rheumatology and Immunology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. Department of Orthodontics, Stomatological Hospital, School of Stomatology Southern Medical University Guangzhou P. R. China The Medical Department, 3D Medicines Inc., Shanghai, China Department of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, P.R. China College of Nursing, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China. Department of Materials Science and Engineering, Faculty of Engineering, NUSNNI-NanoCore, National University of Singapore, 5 Engineering Drive 2, 117576 Singapore State Key Laboratory of Oil and Gas Resources and Prospecting, China University of Petroleum at Beijing, Beijing 102249, China Centre Léon Bérard, Laboratory of constitutional genetics for frequent cancers HCL-CLB, Lyon, France qing.wang@lyon.unicancer.fr. Department of Radiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, P.R. China State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi’an 710032, China State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China Electric Power Research Institute of Guangdong Power Grid Co., Ltd., Guangzhou 510080, China Key Laboratory of High-precision Computation and Application of Quantum Field Theory of Hebei Province, College of Physics Science and Technology, Hebei University, Baoding 071002, China Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University, Qingdao 266003, China School of Life Science, Anhui Agricultural University, Hefei 230036, China Department of Gastroenterology, Shanxi Medical University, Taiyuan, Shanxi 030000, P.R. China Department of Vascular Surgery, The 2nd Xiangya Hospital, Central South University 139 Renmin Middle Road, Changsha 410011, Hunan, People's Republic of China. Department of Ophthalmology, the Affiliated Hospital of Qingdao University, Qingdao 266001, Shandong Province, China. Laboratory for Reproductive Immunology, Hospital and Institute of Obstetrics and Gynecology, Fudan University Shanghai Medical College Shanghai 200011, People's Republic of China. Department of Ophthalmology Stanford University School of Medicine Palo Alto CA USA College of Life Sciences Hebei Agricultural University Baoding China; Key Laboratory of Hebei Province for Plant Physiology and Molecular Pathology Baoding China Shaanxi Engineering Research Centre for Conservation and Utilization of Botanical Resources, Xi’an Botanical Garden of Shaanxi Province (Institute of Botany of Shaanxi Province), Xi’an, China Department of Neurosurgery, Wuxi Second Hospital Affiliated Nanjing Medical University, Wuxi 214002, China Department of Materials Science and Engineering Faculty of Engineering National University of Singapore Singapore 117574 Singapore; National University of Singapore (Suzhou) Research Institute 377 Lin Quan Street, Suzhou Industrial Park Suzhou Jiangsu 215123 P. R. China School of Pharmaceutical Sciences, China Pharmaceutical University, Nanjing, 211198, China Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education) College of Chemistry and Molecular Sciences Wuhan University Wuhan 430000 P. R. China Hefei National Research Center for Physical Sciences at Microscale University of Science and Technology of China Hefei 230026 China Authors' Affiliations: 1Department of Toxicology, Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, Guangzhou; 2Key Laboratory of Chemical Safety and Health, National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing; and 3Department of Toxicology, Shenzhen Center for Disease Control and Prevention, Shenzhen, China State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China Department of Dermatology, Changsha Hospital of Traditional Chinese Medicine (Changsha Eighth Hospital), Changsha, Hunan Province, P.R. China Department of Ophthalmology, Affiliated Hospital of Qingdao University, Qingdao, Shandong, China, School of Nursing and Rehabilitation Shandong University Jinan Shandong China Center of Plastic and Aesthetic Surgery, The First Affiliated Hospital of Harbin Medical University , Nangang District, Harbin City, Heilongjiang Province , P. R. China School of Psychology and Cognitive Science, East China Normal University, Shanghai, China State Key Laboratory of Chemo/Biosensing and Chemometrics; College of Chemistry and Chemical Engineering; Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province; Hunan University; Changsha 410082 School of Chinese Materia Medical, Guangzhou University of Chinese Medicine, Guangzhou 510006, China From the Department of Nutrition, School of Public Health, Sun Yat-Sen University (Northern Campus), Guangzhou, PR China. Department of Plant Breeding, IFZ Research Centre for Biosystems, Land Use and Nutrition, Justus Liebig University, Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany; Programs in Neuroscience, Washington State University, Pullman, Washington, United States Key Laboratory of Molecular Biophysics of the Ministry of Education College of Life Science and Technology and Center for Human Genome Research Huazhong University of Science and Technology Wuhan China; Center for Cardiovascular Genetics Department of Molecular Cardiology Cleveland Clinic Cleveland OH USA; Department of Genetics and Genome Sciences Case Western Reserve University Cleveland OH USA Institute of Pathology, China Three Gorges University, Yichang 443000, China; Department of Pathology, Yichang Central People’s Hospital, Yichang 443003, China Department of General Surgery, The Third Affiliated Hospital of Soochow University (The First People's Hospital of Changzhou), Changzhou, Jiangsu 213000, P.R. China Department of Material Science and Engineering, Beijing University of Technology, 100022, Beijing, China Department of Cardiology Tianjin Medical University General Hospital Tianjin China Key Laboratory of Integrated Regulation and Resource Development of Shallow Lakes, Ministry of Education, College of Environment, Hohai University, Xikang Road #1, Nanjing 210098, China State Key Laboratory of Chemo/Biosensing and Chemometrics; College of Chemistry and Chemical Engineering; Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province; Hunan University; Changsha 410082, China Hefei National Laboratory for Physical Sciences at Microscale School of Life Sciences, University of Science and Technology of China Hefei Anhui People's Republic of China; Key Laboratory of Structural Biology Chinese Academy of Sciences Hefei Anhui People's Republic of China Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong; Institute of Medical Information, School of Biomedical Engineering, Southern Medical University, Guangzhou, China College of Bioengineering, Chongqing University, Chongqing 400044, China. Department of Oncology Qujing No.1 Hospital Qujing China School of Nursing Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China; School of Nursing Lanzhou University Lanzhou China Department of Clinical Laboratory The Affiliated Hospital of Qingdao University Qingdao China Key Laboratory of Fishery Drug Development of Ministry of Agriculture, Pearl River Fishery Research Institute, Chinese Academy of Fishery Sciences, Liwan District, Guangzhou, Guangdong, China Department of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, Guangdong 510630, China Institute and Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, PR China Department of Radiology Qilu Hospital of Shandong University Ji'nan China School of Resources and Materials, Northeastern University at Qinhuangdao, Qinhuangdao 066004, People’s Republic of China; Hebei Key Laboratory of Dielectric and Electrolyte Functional Material, Qinhuangdao 066004, People’s Republic of China Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, College of Chemistry and Materials Science, Zhejiang Normal University, 688 Yingbin Road, Jinhua 321004, P. R. China Affiliated Wuxi Second Hospital, Nanjing Medical University, Wuxi, Jiangsu Province 214122, China Department of Obstetrics and Gynecology, National Key Discipline and Clinical Base, Heilongjiang University of Chinese Medicine, 150040 Harbin, China Department of Pathology and Laboratory Medicine, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey Department of Spinal Surgery, Affiliated Hospital of Luzhou Medical College, Luzhou Sichuan 646000, PR China. wqspine2004@163.com Ludwig Center, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287;; Howard Hughes Medical Institute, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287; Human Genome Research Center and College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, P.R. China School of Basic Medicine, Weifang Medical University, Weifang 261053, P. R. China Department of Materials Science and Engineering, The Pennsylvania State University, University Park, PA 16802 Material Science and Engineering N‐348 Millennium Science Complex The Pennsylvania State University University Park PA 16802 USA Department of Radiology Washington University St. Louis MO USA Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266000, China Department of General Surgery, Zhuzhou Central Hospital , Zhuzhou, Hunan, P. R. China Department of Thoracic Surgery, Tumor Hospital Affiliated to Nantong University, Nantong, Jiangsu Province, China The college of pharmacy and the key laboratory of cardio‐cerebrovascular natural drug research of Hunan province Xiangnan university Hunan China Department of Psychiatry David Geffen School of Medicine University of California Los Angeles Los Angeles California Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, People's Republic of China Wenzhou Seventh People’s Hospital, Zhejiang, China Mallinckrodt Institute of Radiology Washington University School of Medicine St. Louis MO Department of Radiology, Third Affiliated Hospital of Soochow University, Changzhou First People’s Hospital, Changzhou 213200, China Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China Hebei Key Lab of Optic‐Electronic Information and Materials College of Physics Science and Technology Hebei University Baoding 071002 P. R. China State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Biomedical Engineering Center, Institute of Biological Technology, College of Material Science and Technology, Hunan University, Bio-Nano Technology Engineering Research Center of Hunan Province, Changsha 410082, People's Republic of China Beijing Key Laboratory of Pediatric Respiratory Infection Diseases, Key Laboratory of Major Diseases in Children, Ministry of Education, National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics (Capital Medical University), Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, China The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine/Research Center of Neurobiology, Shanxi University of Chinese Medicine, Jinzhong 030619, China State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Rocket Force Medicine Third Military Medical University (Army Medical University) Chongqing China; Institute of Clinical Medicine Southwest Medical University Luzhou China Department of Spine Surgery Affiliated Hospital of Southwest Medical University Luzhou China Department of Endocrinology, China-Japan Union Hospital of Jilin University, Nanguan District, Changchun 13033, P.R. China Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, PR China; Institute of Clinical Pharmacy, Central South University, Changsha, Hunan 410011, PR China Discipline of Diagnostic Radiography University of Sydney Sydney Australia Life Science and Technology Institute, Yangtze Normal University, Chongqing 408100, P. R. China; School of Advanced Agriculture and Bioengineering, Yangtze Normal University, Chongqing 408100, P. R. China MOE Key Laboratory of Major Diseases in Children National Key Discipline of Pediatrics (Capital Medical University) National Clinical Research Center for Respiratory Diseases Beijing Key Laboratory of Pediatric Respiratory Infection Diseases Beijing Pediatric Research Institute Beijing Children’s Hospital Capital Medical University National Center for Children’s Health China Academy of Integrative Medicine, Fujian Key Laboratory of Integrative Medicine on Geriatric Fujian University of Traditional Chinese Medicine Fuzhou China for the Dominantly Inherited Alzheimer Network School of Computer Science and Engineering, South China University of Technology, Guangzhou 510006, China Centre Léon Bérard; Molecular Biology Platform; Center of Translational Research; Lyon France; Centre Léon Bérard; Laboratory of Constitutional Genetics for Frequent Cancers HCL-CLB; Lyon France National Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Department of Cardiology, Tianjin Medical University General Hospital, Tianjin Department of Toxicology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu 610041, China. Department of Ophthalmology Stanford University School of Medicine Palo Alto California USA Department of Orthopedics, Affiliated Hospital of Southwest Medical University, Luzhou, China Department of Respiratory and Critical Care Medicine, The Third Affiliated People’s Hospital of Fujian University of Traditional Chinese Medicine , Fuzhou 350108, Fujian , China School of Advanced Agriculture and Bioengineering Yangtze Normal University Chongqing People's Republic of China School of Environmental and Chemical Engineering Shanghai University 99 Shangda Road Shanghai 200444 P. R. China Affiliated Hospital of Qingdao University, China Department of Radiology, Qilu Hospital of Shangdong University, China Chinese Academy of Sciences; University of Chinese Academy of Sciences Plateforme de génomique des cancers Centre Léon Bérard, Laboratoire de la génétique constitutionnelle HCL‐CLB Lyon France Department of Clinical Laboratories, The Medical School Hospital of Qingdao University, Qingdao, China Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China All authors: Department of Plant Breeding, IFZ Research Centre for Biosystems, Land Use and Nutrition, Justus Liebig University, Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany. Department of Neurosurgery The Second Affiliated Hospital of Soochow University Suzhou China Department of Ophthalmology, The First Affiliated Hospital of Anhui Medical University, Hefei, China School of Chinese Materia Medica Beijing University of Chinese Medicine Beijing P. R. China Institute of Agri‐food Processing and Nutrition Key Laboratory of Vegetable Postharvest Processing of Ministry of Agriculture and Rural Areas, Beijing Key Laboratory of Fruits and Vegetable Storage and Processing, Beijing Academy of Agricultural and Forestry Sciences Beijing 100097 China 1 Department of Biochemistry, Dartmouth Medical School, Hanover, NH 03755, USA Key Laboratory of Advanced Technologies of Materials (Ministry of Education) School of Materials Science and Engineering Southwest Jiaotong University Chengdu 610031 China School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China College of Materials Science and Engineering, Shandong University of Science and Technology, Qingdao 266590, China Department of Endocrinology, China-Japan Union Hospital, Changchun, Jilin 130033, China. School of Pharmaceutical Science & Technology, Dalian University of Technology 2 , Dalian 116023, China Contribution from the Laboratory for Photonics and Interfaces, Ecole Polytechnique Fédérale, CH-1015 Lausanne, Switzerland, and Department of Organic Chemistry II, University of Ulm, 89081 Ulm, Germany Institute for Medical Dataology Shandong University Jinan People’s Republic of China School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001,China College of Environmental Science and Engineering, Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria, Nankai University, Tianjin 300071, China Department of Ophthalmology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA; Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, NY, USA From the Parkinson’s Disease Center and Movement Disorders Clinic (Dr. Ondo and K.D. Vuong), Department of Neurology, Baylor College of Medicine, Houston, TX; and the Center for Molecular Genetics, Department of Molecular Cardiology, and Department of Cardiology (Dr. Wang), The Cleveland Clinic Foundation, Cleveland, OH. Department of Animal and Food Sciences, University of Delaware, Newark, Delaware. National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China Department of Radiology, Qilu Hospital of Shandong University, Jinan 250012, China College of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, China School of Materials Science and Engineering Northeastern University 110819 Shenyang PR China; School of Resources and Materials Northeastern University at Qinhuangdao 066004 Qinhuangdao PR China; Hebei Key Laboratory of Dielectric and Electrolyte Functional Material 066004 Qinhuangdao PR China College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology Wuhan, China ; Department of Molecular Cardiology, Center for Cardiovascular Genetics, Lerner Research Institute, Cleveland Clinic Cleveland, OH 44195, USA. Henan University People's Hospital, Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, Zhengzhou 450003, China Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China; Department of Respiratory and Critical Care Medicine of Kunming Municipal First People's Hospital, Kunming, Yunnan 650000, China Department of Radiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China Center for Molecular Genetics, Department of Molecular Cardiology, Lerner Research Institute, Department of Cardiology, The Cleveland Clinic Foundation, Cleveland, OH 44195 Key Laboratory of Fishery Drug Development of Ministry of Agriculture, Key Laboratory of Aquatic Animal Immune Technology of Guangdong Province, Pearl River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, P.R. China State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products, College of Life Sciences, Zhejiang University, Hangzhou 310058, China *Center for Structural Biology, School of Life Sciences, Ministry of Education Key Laboratory of Protein Science, Tsinghua University, Beijing 100084, People’s Republic of China; and Tongji School of Pharmacy Huazhong University of Science and Technology Wuhan China Department of Materials Science and Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802 Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, China Chinese Academy of Fishery science Pearl River Fisheries Research Institute Guangzhou PR China Department of Radiology, Changshu No. 2 People's Hospital The Affiliated Changshu Hospital of Xuzhou Medical University Changshu Jiangsu China State Key Laboratory of Pulp & Paper Engineering; South China University of Technology; Guangzhou 510640; China Department of Pharmacology; College of Pharmacy; Ningxia Medical University; Yinchuan 750004; P. R. China Dept. of Economic, School of Business, Dalian University of Technology, Panjin, Liaoning, China. Dept. of Social Medicine and Maternal & Child Health, School of Public Health, Shandong University, Jinan, Shandong, China. Department of Epidemiology and Statistics Key Laboratory of Environmental Medicine Engineering of Ministry of Education School of Public Health Southeast University Nanjing Jiangsu China Plateforme de Génétique constitutionnelle HCL-CLB, Laboratoire de recherche translationnelle, Centre Léon Bérard, Lyon, France. Division of Hematology-Oncology, Department of Internal Medicine, Medical School, University of Michigan, Ann Arbor, MI; Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes, Ministry of Education, College of Environment, Hohai University, Nanjing, Jiangsu 210098, P.R. China Department of Oral Medicine, College of Stomatology, Shandong University, Jinan 250012, Shandong Province, China. wangqing@sdu.edu.cn Department of Neurosurgery, Wuxi Neurosurgical Institute, Jiangnan University, Wuxi, Jiangsu 214002, People’s Republic of China; Department of Neurosurgery, Jiangnan University Medical Center, Wuxi, Jiangsu 214122, People’s Republic of China Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03755 *Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Zhejiang 310003, People’s Republic of China; ICGM Univ. Montpellier CNRS ENSCM Montpellier France Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China School of Food and Biological Engineering Jiangsu University Zhenjiang 212013 China School of Chemistry and Chemical Engineering and Key Laboratory of Thin Film and Microfabrication, (Ministry of Education) Shanghai Jiao Tong University Shanghai 200240 China From the Mallinckrodt Institute of Radiology (Q.W., G.C., J.C., S.F., R.H., Z.T., Y.W., T.L.S.B.), Washington University School of Medicine; Knight Alzheimer Disease Research Center (Q.W., G.C., S.E.S., J.H., L.C., A.M.F., J.C.M., T.L.S.B.), Washington University School of Medicine; Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Washington University School of Medicine; Department of Surgery (J.L.), Washington University School of Medicine; Department of Electrical and System... State Key Laboratory of Crop Genetics and Germplasm Enhancement, JCIC-MCP, Nanjing Agricultural University, Nanjing 210095, China. School of Pharmaceutical Science and Technology, Dalian University of Technology, 2 Linggong Road, Dalian, Liaoning 116024, China Department of Cardiology Second Hospital of Hebei Medical University Shijiazhuang China Department of Neurology The Third Affiliated Hospital of Sun Yat‐Sen University Guangzhou Guangdong China State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, Dalian, China School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China Tongji School of Pharmacy Huazhong University of Science and Technology Wuhan P. R. China Contribution from the Laboratory for Photonics and Interfaces, Ecole Polytechnique Fédérale, CH-1015 Lausanne, Switzerland Department of Orthopaedics, The Affiliated Hospital of Southwest Medical University Luzhou China Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, New Jersey 08854-8022, Department of PediatricsNeonatology, UMDNJRobert Wood Johnson Medical School, New Brunswick, New Jersey 08903, Lakewood Pathology Associates, Lakewood, New Jersey 08701, Bristol-Myers Squibb Research Institute, Discovery Pharmaceutics, PO Box 4000 Princeton, New Jersey 08543, and Absorption Systems LP, Oaklands Corporate Center, 440 Creamery... Department of Materials Science and Engineering, Faculty of Engineering, National University of Singapore, Singapore 117576, Singapore. Department of Allergy and Immunology, Walter Reed National Military Medical Center , Bethesda, MD 20892, USA Department of Pathology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, USA Department of Dermatology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, P.R. China Tianjin International Joint Research and Development Centre of Ophthalmology and Vision Science; Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China Guangdong Provincial Key Laboratory of Food,Nutrition and Health,Department of Toxicology,School of Public Health,Sun Yat‐sen University,Guangzhou,China Beijing Key Laboratory of Energy Conversion and Storage Materials and College of Chemistry, Beijing Normal University, Beijing 100875, China Biomedical Engineering Center, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China Department of Cardiothoracic Surgery, Changzheng Hospital, Second Military Medical University, Fengyang Road 415#, Shanghai 200003, China Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology Changzhou University Changzhou 213164 China Department of Ecology Key Laboratory of Philosophy and Social Science in Guangdong Province Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai) Jinan University Guangzhou P. R. China Département de Biopathologie Centre Léon Bérard Lyon France Medical College of Nankai University, Tianjin 300071, PR China F. Hoffmann‐La Roche Innovation Center Basel Switzerland Guang’anmen Hospital of China Academy of Chinese Medical Sciences; Beijing University of Chinese Medicine State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio‐Nanotechnology and Molecular Engineering of Hunan Province Hunan University Changsha China Key Lab of Environment-friendly Chemistry and Application in Ministry of Education, and Key Laboratory of Advanced Functional Polymer Materials of Colleges, Universities of Hunan Province and College of Chemistry, Xiangtan University, Xiangtan, Hunan 411105, China The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine Shanxi University of Traditional Chinese Medicine Taiyuan China Programs in Neuroscience, Washington State University, Pullman, WA Xiangya School of Pharmaceutical Science, Central South University, Changsha, Hunan 410013, China National Key Laboratory of Crop Genetics and Germplasm Enhancement, National Center for Soybean Improvement, Nanjing Agricultural University Unité d'Oncologie Moléculaire and Institut National de la Santé et de la Recherche Médicale U590, Centre Léon Bérard, 69008 Lyon, France; and College of Food & Pharmaceutical Engineering Guizhou Institute of Technology Guiyang China Department of Spinal Surgery, Affiliated Hospital of Southwest Medical University, Luzhou Sichuan, 646000, P.R.China.wqspine2004@163.com. Programs in Neuroscience, Washington State University, Pullman, Washington Department of Anesthesiology, First Affiliated Hospital of Anhui Medical University Department of Pulmonary Medicine, The First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China Department of Clinical Nutrition, Sun Yat-sen University (Northern Campus), 74 Zhongshan Road II. Guangzhou, China 510080. Department of Materials Science and Engineering The Pennsylvania State University University Park Pennsylvania 16802 USA State Key Laboratory of Silicate Materials for Architectures School of Materials Science and Engineering Wuhan University of Technology Luoshi Road 122 Wuhan 430070 P. R. China; Department of Materials Science and Engineering The Pennsylvania State University University Park Pennsylvania 16802 USA Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China MacDiarmid Institute for Advanced Materials and Nanotechnology, School of Chemical Sciences, The University of Auckland, Auckland 1142, New Zealand Department of Endocrinology and Metabolism The Affiliated Hospital of Qingdao University Qingdao China State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China College of Life Science, Shanxi Normal University, Taiyuan 030031, China Institute of Polar Environment; School of Earth and Space Sciences; University of Science and Technology of China; Hefei City, P. R China Department of Ophthalmology, Affiliated Hospital of Qinghai University, No. 29 of Tongren Road, Xining 810000, Qinghai Province, China School of Materials Science and Engineering Northeastern University Shenyang 110819 P. R. China; Key Laboratory of Dielectric and Electrolyte Functional Material Hebei Province School of Resources and Materials Northeastern University at Qinhuangdao Qinhuangdao 066004 P. R. China Department of Orthopaedics Surgery, Ningbo No.6 Hospital, Ningbo 315040, Zhejiang, China. Department of Oncology Wuhan Iron and Steel (Group) Corporation Staff‐Worker Hospital Wuhan 430085 China Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China. Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom Department of Obstetrics, Bao Ji People’s Hospital, Bao Ji, China Department of Neurology, Affiliated ZhongDa Hospital, School of Medicine, Southeast University, Nanjing, China. Absorption Systems, Exton, PA, USA, and Department of Radiology; the First Affiliated Hospital with Nanjing Medical University; Nanjing China College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China; Anhui Province Key Laboratory of Veterinary Pathobiology and Disease Control, Hefei 230036, China College of Medical Information Engineering, Anhui University of Traditional Chinese Medicine, Hefei 230012, China School of Petroleum Engineering, China University of Petroleum, Beijing 102249, China Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Daejeon 34141, South Korea; Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea Key Laboratory of Integrated Regulation and Resource Development of Shallow Lakes; Ministry of Education; College of Environment; Hohai University; Nanjing 210098 Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, 266071, P. R. China Department of Pharmacy, Xinqiao Hospital, Army Medical University, Chongqing 400037, P.R.�China College of Resource, Environment and Tourism Capital Normal University Beijing China National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural University Wuhan Hubei China Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, China 2Department of Neurosurgery, The Affiliated Wuxi No. 2 People's Hospital of Nanjing Medical University, Wuxi, P.R. China. Department of Dermatology Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China University of New Mexico Albuquerque New Mexico USA Department of Nutrition, Tianjin Chest Hospital, Tianjin, China; School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China Department of Oncology, Shanghai Medical College, Fudan UniversityShanghai, China; Department of Oncology, Jing'an District Center Hospital of Shanghai (Huashan Hospital, Fudan University, Jing'an Branch)259 Xikang Road, Shanghai 200040, China; Department of Oncology, Huashan Hospital, Fudan University12 Urumqi Road, Shanghai 200040, China. Key Laboratory of Aquatic Animal Immune Technology of Guangdong Province and Key Laboratory of Fishery Drug Development of Ministry of Agriculture, Pearl River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, China Department of Hematology, The People’s Hospital of Guizhou Province, Guiyang, Guizhou, People’s Republic of China Obstetrics and Gynecology Hospital, Fudan University Shanghai 200011, China. Jilin Provincial Academy of Traditional Chinese Medicine Department of Radiology, Third Affiliated Hospital of Soochow University, Changzhou & Changzhou First People’s Hospital , Juqian street NO.185, Tianning district , Changzhou, Jiangsu, 213003, China Department of Neurology Zhujiang Hospital of Southern Medical University Guangzhou Guangdong China Department of Materials Science and Engineering, National University of Singapore, Singapore 117576, Singapore School of Computer and Information Science, Southwest University, Chongqing 400715, China Centre for THz Research, China Jiliang University, Hangzhou 310018, China School of Nursing and Rehabilitation, Shandong University, Jinan, Shandong, PR China School of Nature Conservation Beijing Forestry University Beijing China; Department of Forest and Conservation Sciences, Faculty of Forestry The University of British Columbia Vancouver British Columbia Canada State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China College of Life Science, Sichuan Agricultural University, Ya’an, China; Department of Respiratory Diseases, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China State Key Laboratory of Food Nutrition and Safety Key Laboratory of Food Nutrition and Safety Ministry of Education of China College of Food Science and Engineering Tianjin University of Science and Technology Tianjin 300457 P. R. China Shandong Youth University of Political Science, Jinan, Shandong 250103, China School of Pharmaceutical Science and Technology, Tianjin University Shanghai Normal University 1 Key Laboratory of Optoelectronic Material and Device, Department of Physics, , Shanghai 200234, China Academy of Nutrition and Health, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Public Health, Wuhan University of Science and Technology, Wuhan, China F. Hoffmann-La Roche Ltd., Basel, Switzerland State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio‐Nanotechnology and Molecular Engineering of Hunan Province College of Biology, Hunan University Changsha 410082 China College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei, 430072, P. R. China Washington University in St. Louis St. Louis Missouri USA Collaborative Innovation Center of Tumor Marker Detection Technology, Equipment and Diagnosis-Therapy Integration in Universities of Shandong, Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi 276005, China Tongji School of Pharmacy Huazhong University of Science and Technology Wuhan 430030 China; Tianjin Key Laboratory of Food Biotechnology, College of Biotechnology and Food Science Tianjin University of Commerce Tianjin 300134 China Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China. qwang@iue.ac.cn Department of Ophthalmology, the Affiliated Hospital of Medical College, Qingdao University, Qingdao - China Beijing Key laboratory of the Innovative Development of Functional Staple and the Nutritional Intervention for Chronic Disease Beijing China; China National Research Institute of Food and Fermentation Industries Beijing China College of Civil Engineering and Architecture, Shandong University of Science and Technology, Qingdao 266590, China School of Chinese Materia Medica, Beijng University of Chinese Medicine, Beijing 100102, China. Department of Endocrine and metabolic diseases, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China Department of Hematology, The People’s Hospital of Guizhou Province, Guiyang, Guizhou, China (mainland) Department of Neurology, Affiliated ZhongDa Hospital, School of Medicine, Southeast University, Nanjing 210009, Jiangsu, China State Key Lab. of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry, Shanghai, China Key Laboratory of Fishery Drug Development of Ministry of Agriculture, Key Laboratory of Aquatic Animal Immune Technology of Guangdong Province, Pearl River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, Guangdong, the People’s Republic of China (Zheng, Q Wang, Li, Zeng, Y Wang, Liu, Shi); College of Fisheries and Life Science, Shanghai Ocean University, Shanghai, the People’s Republic of China (Zheng); German Reference Laboratory for KHVD, Institute of Infectology, Friedrich-Loffler-Institut (FLI), Federal Research Institute for Animal Health, Greifswald–Insel Riems, Germany (Bergmann). Guangdong Provincial Key Laboratory of Food Department of Nutrition School of Public Health, Sun Yat‐Sen University (Northern Campus) Guangzhou China School of Chemical Sciences The University of Auckland Auckland 1142 New Zealand Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei, China Laboratory for Microstructures Institute of Materials Science, Shanghai University, Shanghai 200072, China Department of Surgery, Nantong Tumour Hospital, Nantong Jiangsu, 226361, P.R.China. Laboratory of Cancer Prevention and Basic Research Program, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland 21702 Department of Chemical and Biomolecular Engineering, The University of Akron, Akron, OH, 44325-3906, United States State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China; National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China Department of Cardiology, Tianjin Medical University General Hospital School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou 510515, China; Guangdong Province Engineering Laboratory for Medical Imaging and Diagnostic Technology, Southern Medical University, Guangzhou 510515, China Department of Ophthalmology, Heji Hospital Affiliated to Changzhi Medical College, Changzhi, P.R. China Institute of Agro-Products Processing and Food Nutrition Key Laboratory of Vegetable Postharvest Processing, Ministry of Agriculture, Beijing Key Laboratory of Fruits and Vegetable Storage and Processing, Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (North China) of Ministry of Agriculture, Key Laboratory of Urban Agriculture (North) of Ministry of Agriculture, Beijing Vegetable Research Center, , Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China Institute of Hypoxia Medicine, Teaching Center of Medical Functional Experiment, Wenzhou Medical College, Wenzhou 325035, China. School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China BGI Education Center University of Chinese Academy of Sciences Shenzhen China Department of Obstetrics and Gynecology, Xuzhou Central Hospital, Xuzhou, China. State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei, China Google Research, Mountain View, CA 94043; Institute of Medical Information, School of Biomedical Engineering, Southern Medical University, Guangzhou, China School of Pharmacy, Henan University of Chinese Medicine , Zhengzhou, Henan Province , China Department of General Surgery, The Third Affiliated Hospital of Soochow University and The First People’s Hospital of Changzhou, Changzhou, Jiangsu, China Department of Orthopaedics The Affiliated Hospital of Southwest Medical University Luzhou China Department of Ophthalmology, the First Affiliated Hospital of Anhui Medical University, Hefei 230031, Anhui Province, China. Department of Ophthalmology, the Fourth Affiliated Hospital of Anhui Medical University, Hefei 230012, Anhui Province, China. Washington University in St. Louis *Department of Respiratory Diseases, First Affiliated Hospital of College of Medicine and State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha, Hunan 410082, P. R. China Department of Ophthalmology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.; Edward S. Harkness Eye Institute, Columbia University, Irving Medical Center, New York, New York, USA. School of Chinese Materia Medicine; Beijing University of Chinese Medicine; Beijing China From Lillie Frank Abercrombie Section of Cardiology, Department of Pediatrics (H.L, Q.C., V.G., S.W.D., Q.W., J.A.T.), and Department of Molecular and Human Genetics (J.A.T.), Baylor College of Medicine, Houston, Tex; Children’s Hospital and Health Center, San Diego, Calif (J.C.P.); Department of Medicine, University of Rochester Medical Center, Rochester, NY (A.J.M., J.R.); Department of Medicine, LDS Hospital and University of Utah School of Medicine, Salt Lake City (G.M.V.); Department of... School of Microelectronics, Southern University of Science and Technology, Shenzhen 518055, China College of Chemistry and Chemical Engineering; Xinjiang Normal University; Urumqi; China 2Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI Research and Development Center for Efficient Utilisation of Coastal Bioresources, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China College of Chemical Engineering Sichuan University Chengdu Sichuan China Department of Gynaecology and Obstetrics, Anhui Provincial Hospital, Hefei, Anhui, China Key Laboratory of the Vegetable Postharvest Treatment of Ministry of Agriculture, Beijing Key Laboratory of Fruits and Vegetable Storage and Processing, Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (North China) of Ministry of Agriculture, Key Laboratory of Urban Agriculture (North) of Ministry of Agriculture, Beijing Vegetable Research Center Beijing Academy of Agriculture and Forestry Sciences Beijing China Department of Ophthalmology, Bernard and Shirlee Brown Glaucoma Research Laboratory, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, NY Programs in Neuroscience, Washington State University, Pullman, Washington 99164–7620 The Second Surgical Department of Breast Cancer Tianjin Medical University Cancer Institute and Hospital Tianjin China 4Anhui Chest Hospital, Hefei, Anhui, China. Medical Research Council Biostatistics Unit, Cambridge, United Kingdom. School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China Department of Neonatology, Hainan Modern Women and Children’s Hospital, Haikou, Hainan, China National Key Laboratory of Electromagnetic Energy, Naval University of Engineering, Wuhan 430033, China MOE Key Laboratory of Major Diseases in Children, National Key Discipline of Pediatrics (Capital Medical University) National Clinical Research Center for Respiratory Diseases, Beijing Key Laboratory of Pediatric Respiratory Infection Diseases, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, China; Laboratory of Microbiology, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, Beijing, China School of Materials Science and Engineering Northeastern University 110819 Shenyang P. R. China; School of Resources and Materials Northeastern University at Qinhuangdao 066004 Qinhuangdao P. R. China; Key Laboratory of Dielectric and Electrolyte Functional Material Hebei Province 066004 Qinhuangdao P. R. China Department of General Surgery, Tangdu Hospital of The Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China State Key Laboratory of Reproductive Regulation & Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010021, China Division of Hypertension and Vascular Medicine, Centre Hospitalier Universitaire Vaudois, CH-1011 Lausanne, Switzerland Key Laboratory of Textile Science and Technology Ministry of Education Donghua University Shanghai 201620 China School of Nursing Nanjing university of Chinese Medicine Nanjing Jiangsu Province China Department of Nursing, Institute of Nursing and Rehabilitation North China University of Science and Technology Tangshan Hebei China Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou 213164, China Academy of Nutrition and Health, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Public Health Wuhan University of Science and Technology Wuhan China School of Microelectronics Southern University of Science and Technology Shenzhen 518055 China Johns Hopkins University, Baltimore, United States Key Laboratory of Human Genetics and Environmental Medicine, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People’s Republic of China; Key Lab of Environment and Health, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People’s Republic of China National Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, People’s Republic of China Department of Surgery, University of Virginia, Charlottesville, VA 22908;; Carter Immunology Center, University of Virginia, Charlottesville, VA 22908; Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China; National Institute of Health Data Science of China, Shandong University, Jinan, Shandong, China Department of Laboratory The Second People's Hospital of Jiaozuo the First Affiliated Hospital of Henan Polytechnic University Jiaozuo China Department of Andrology , Nanjing, , China; Jiangsu Province Hospital of Chinese Medicine , Nanjing, , China; Affiliated Hospital of Nanjing University of Chinese Medicine , Nanjing, , China Joint Laboratory of Constitutional Genetics on Frequent Cancers HCL‑CLB, Cancer Genomics Platform, Centre L�on B�rard, Lyon 69008, France Key Laboratory of Photosynthesis and Environmental Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China School of Biomedical Informatics The University of Texas Health Science Center at Houston Houston TX USA State Key Laboratory of Chemo/Biosensing and Chemometrics; College of Chemistry and Chemical Engineering; Key Laboratory for Bio-Nanotechnology and Molecule Engineering of Hunan Province; Hunan University; Changsha Ministry of Education Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes, College of Environment, Hohai University, Nanjing, People's Republic of China Department of Clinical Laboratory Centre, Shaoxing People’s Hospital , Shaoxing 312000, Zhejiang , P.R. China Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles College of Agronomy, Gansu Agricultural University, Lanzhou 730070, China. Department of Endocrinology, Guang’anmen Hospital of China, China Academy of Chinese Medical Sciences, Beijing 100054, China; Laboratory of Molecular and Biology, Guang’anmen Hospital of China, China Academy of Chinese Medical Sciences, Beijing 100053, China Department of Pediatrics, Affiliated Hospital of Jiangnan University, Wuxi, China School of Material Science and Engineering Institute of Nano Engineering Shandong University of Science and Technology Qingdao Shandong 266590 China The State Key Laboratory of Natural and Biomimetic Drugs; Department of Chemical Biology; School of Pharmaceutical Sciences; Peking University; Beijing 100191 School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, China Jiangsu Key Laboratory for the Research and Utilization of Plant Resources, Research Center of Ornamental Plants, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, China. National University of Singapore College of Design and Engineering Materials Science and Engineering Blk E2-05-27 NUS 117579 Singapore SINGAPORE Department of Physics, The University of Texas at Dallas, Richardson, Texas 75080, United States Department of Pharmacy The Second Affiliated Hospital of Army Medical University Chongqing China Department of Neurology, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, P.R. China Department of Surgery, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, China The Second Department of Geriatrics Xiyuan Hospital, China Academy of Chinese Medical Sciences Beijing China; National Clinical Research Center for Traditional Chinese Medicine Cardiology, Xiyuan Hospital, China Academy of Chinese Medical Sciences Beijing China School of Material Science & Engineering, Shandong University of Science and Technology, Qingdao, 266590, P.R. China School of Materials Science and Engineering; Harbin Institute of Technology; Harbin 150001; China; Tianjin Key Laboratory for Photoelectric Materials and Devices Beijing Academy of Agricultural and Forestry Sciences Institute of Agri-food Processing and Nutrition, , Beijing Key Laboratory of Fruits and Vegetable Storage and Processing, Key Laboratory of Vegetable Postharvest Processing of Ministry of Agriculture and Rural Areas, Beijing 100097, China Department of Psychiatry and Biobehavioral Sciences Shirley and Stefan Hatos Center for Neuropharmacology Semel Institute for Neuroscience and Human Behavior David Geffen School of Medicine University of California Los Angeles Los Angeles CA USA From the Departmentx of Pediatrics (Cardiology) (Q.C., D.Z., Q.W., J.A.T.) and Molecular and Human Genetics (J.A.T.), Baylor College of Medicine, Texas Children’s Hospital, Houston, Tex; Children’s Hospital at Buffalo, Buffalo, NY (R.L.G.); Department of Medicine (A.J.M., E.K., J.L.R.,) and Department of Community and Preventive Medicine (J.L.R.), University of Rochester Medical Center, Rochester, NY; Department of Cardiology, University of Pavia, and Policlinico S. Matteo, IFCCS, Pavia, Italy (C.N.... Fourth Military Medical University, China Laboratory for Photonics and Interfaces, Institute of Chemical Sciences and Engineering, School of Basic Sciences, Swiss Federal Institute of Technology, CH-1015 Lausanne, Switzerland, Department of Physical Chemistry, University of Uppsala, Box 532, SE-75121 Uppsala, Sweden, Department of Chemistry, University of Basel, Spitalstrasse 51, 4056 Basel, Switzerland, Centre for Electronic Materials and Devices, Department of Chemistry, Imperial College, Exhibition Road, SW7 2AZ London, U.K., and Department... Function Experiment Teaching Center, Wenzhou Medical University, Wenzhou, China 325305. Department of Pneumology, The First People's Hospital‑Calmette Hospital of Kunming, Kunming, Yunnan 650224, P.R. China Materials Science and Engineering Department, Pennsylvania State University, University Park, PA 16802, USA.; Materials Research Institute, Pennsylvania State University, University Park, PA 16802, USA.; Electrical Engineering Department, 5 Rue du General Cassagnou, 68300 Saint-Louis, France.; Institute Franco-Allemand de Recherches, 5 Rue du General Cassagnou, 68300 Saint-Louis, France. Academy of Traditional Chinese Medicine, Changchun, Jilin 130021, P.R. China Department of Materials Science and Engineering National University of Singapore Blk. E2, #05-27, 5 Engineering Drive 2 Singapore 117579 Singapore Department of Orthopedics, Hospital of Southwest Medical University, Luzhou, China grid.419897.a 000000040369313X Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin Industrial Microbiology Key Laboratory 300457 Tianjin People’s Republic of China; grid.413109.e 0000000097356249 College of Bioengineering Tianjin University of Science and Technology No. 29, 13th Avenue, TEDA-Tianjin Economic-Technological Development Area 300457 Tianjin People’s Republic of China Department of Pulmonary and Critical Care Medicine, Dongfang Hospital Affiliated to Xiamen University, Fuzhou, Fujian, China Department of Materials Science and Engineering, Pennsylvania State University, University Park, Pennsylvania 16802, United States Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, Washington Faculty of Materials Science and Chemistry China University of Geosciences Wuhan 430074 China; Department of Materials Science and Engineering The Pennsylvania State University University Park Pennsylvania 16802 USA Department of Urology, Guizhou Provincial People’s Hospital, Guizhou University, Guiyang, Guizhou, China; Department of Research Laboratory Center, Guizhou Provincial People’s Hospital, Guizhou University, Guiyang, Guizhou, China Department of Ophthalmology, Jinhua Central Hospital, Jinhua 321000, China. wangqcy@gmail.com Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, China; Shanghai Medical Center of Key Programs for Female Reproductive Diseases, Shanghai, China State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang Province, China State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan 430072, Hubei, China Xiangya School of Pharmaceutical Science, Central South University, Changsha, Hunan, 410013, P. R. China Programs in Neuroscience, College of Veterinary Medicine, Washington State University, Pullman, Washington 99164-6520 School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, People’s Republic of China National Center for Soybean Improvement, National Key Laboratory of Crop Genetics and Germplasm Enhancement, Jiangsu Collaborative Innovation Center for Modern Crop Production Nanjing Agricultural University Nanjing China Faculty of Preventive Medicine, A Key Laboratory of Guangzhou Environmental Pollution and Risk Assessment, School of Public Health Sun Yat‐sen University Guangzhou 510080 China Tsinghua National Laboratory for Information Science and Technology Tsinghua University Beijing China Shanghai Academy of Environmental Sciences, Shanghai 200233, China. Northeastern University School of Materials Science and Engineering, Shenyang 110819, Liaoning, People’s Republic of China; School of Resources and Materials, Northeastern University at Qinhuangdao, Qinhuangdao 066004, People’s Republic of China; Hebei Key Laboratory of Dielectric and Electrolyte Functional Material, Qinhuangdao 066004, Hebei, People’s Republic of China Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322; and Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322 Key Laboratory of Molecular Biophysics of the Ministry of Education, Cardio-X Institute, College of Life Science and Technology and Center of Human Genome Research, Huazhong University of Science and Technology , Wuhan , China Anhui Key Laboratory of Resource Insect Biology and Innovative Utilization, School of Life Sciences Anhui Agricultural University Hefei China Department of Neonatology, Children’s Hospital affiliated to Soochow University, China Department of Microbiology, Tianjin Medical University, Tianjin 300070, China. wangqing_diamond@yahoo.com.cn State Key Laboratory for Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu Province, 210095, P.R. China; Collaborative Innovation Center for Modern Crop Production co-sponsored by Province and Ministry, Nanjing, Jiangsu Province, 210095, P.R. China; College of Agriculture, Nanjing Agricultural University, Nanjing, Jiangsu Province, 210095, P.R. China Department of Materials Science and Engineering National University of Singapore 117576 Singapore Singapore Research Center of Neurobiology Shanxi University of Traditional Chinese Medicine Taiyuan China Department of Endocrinology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100054, China Department of Pacing and Electrophysiology, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China; Xinjiang Key Laboratory of Cardiac Electrophysiology and Cardiac Remodeling, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China. Respiratory Department of Kunming Municipal First People’s Hospital , Kunming 650000 , China; Graduate School, Tianjin Medical University General Hospital , Tianjin 300052 , China Laboratory for Photonics and Interfaces, Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland, Departament de Ciències Experimentals, Universitat Jaume I, 12071 Castelló, Spain, and Environmental Material Laboratory, Material Science of Engineering, Graduate School of Engineering, Shibaura Institute of Technology 3-9-14, Shibaura, Minatoku, Tokyo, Japan 108-8548 Yunnan Key Laboratory of Statistics Modeling and Data Analysis Yunnan University Kunming China Institute of Rocket Force Medicine, State Key Laboratory of Trauma, Burns and Combined Injury, Third Military Medical University (Army Medical University), Chongqing 400038, China; Institute of Clinical Medicine, Southwest Medical University, 646000 Luzhou, China Graduate College, Beijing University of Traditional Chinese Medicine, Beijing 100029, China School of Pharmaceutical Science and Technology, Dalian University of Technology, Dalian 116024, China. Anhui Chest Hospital, Hefei, China Department of Pharmacology School of Pharmacy Fudan University Shanghai China State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences Peking University 38 Xueyuan Road Beijing 100191 China State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Collaborative Innovation Center of Advanced Microstructures, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China 1State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Changchun University of Science and Technology, WeiXing Road 7989, Changchun 130022, China Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou 510406, China Departments of Neurosurgery and 2011 Collaborative Innovation Center/Research Center of Neurobiology, Shanxi University of Traditional Chinese Medicine, Shanxi Province, People's Republic of China. Department of Urology, Guizhou Provincial People's Hospital, Guiyang, Guizhou, 550000, China. Department of Cardiology, Tianjin Medical University General Hospital, Tianjin, China (mainland) Department of Orthopedics, The First Affiliated Hospital of Soochow University, Orthopedic Institute, Medical College, Soochow University Department of Materials Science and Engineering; Faculty of Engineering; NUSNNI-NanoCore; National University of Singapore; Singapore Department of Stomatology , Weifang People’s Hospital , Weifang , China Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, P. R. China Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, Hubei, PR China Department of Chemistry; National University of Singapore; Singapore Department of Orthopaedics, The First Affiliated Hospital of Soochow University, 188 Shizi Street, Suzhou, Jiangsu 215006, China Department of Toxicology, School of Public Health Sun Yat‐sen University, Guangzhou, Guangdong, China School of Civil Engineering and Architecture, Shandong University of Science and Technology, Qingdao, Shandong 266590, China Research Center for Materials Science and Graduate School of Science, Nagoya University, Chikusa, Nagoya 464-8602, Japan Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, China. Henan University People’s Hospital, Henan Provincial People’s Hospital, Henan Eye Hospital, Henan Eye Institute, Zhengzhou 450003, China School of Life and Environmental Sciences Guilin University of Electronic Technology Guilin 541004 Guangxi P. R. China 1Department of Neurosurgery, The Affiliated Wuxi No. 2 People’s Hospital of Nanjing Medical University, Wuxi 214002, China; 3Department of Neurosurgery, The Affiliated Wuxi Clinical College of Nantong University, Wuxi 214002, China Department of Endodontics,College of Stomatology, Shandong University. Jinan 250012,Shandong Province, China.E-mail:wangqing@sdu.edu.cn. School of Mathematical Sciences, Zhejiang University, Hangzhou 310058, China State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology Sichuan University Chengdu China Department of Physics University of Texas at Dallas 800 West Campbell Road Richardson TX 75080 USA Department of Vascular Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China Hubei Key Laboratory of Cell Homeostasis, Frontier Science Center for Immunology and Metabolism, College of Life Sciences Wuhan University Wuhan China School of Chinese Materia Medica; Beijing University of Chinese Medicine; Beijing P. R. China; Science Experiment Center for Traditional Chinese Medicine; Beijing University of Chinese Medicine; Beijing P. R. China Shenyang Mylike Medical Cosmetic Hospital, Shenyang, China. Jiangsu Key Laboratory for the Research and Utilization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing Botanical Garden, Memorial Sun Yat-Sen, No. 1 Qianhu Houcun, Nanjing 210014, China Departments of Neurology, Psychiatry and Human Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA. Key Laboratory of Fishery Drug Development, Ministry of Agriculture and Rural Affairs, Key Laboratory of Aquatic Animal Immune Technology, Guangdong Province, Pearl River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510380, China Department of Neurosurgery Jiangnan University Medical Center Wuxi Jiangsu 214002 P. R. China State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro‐Products, College of Life Sciences Zhejiang University Hangzhou China Department of Pathology, Anhui Province Maternity and Child Health Hospital Anhui Medical University Hefei China Departments of Materials Science and Engineering and Electrical Engineering, Materials Research Institute, The Pennsylvania State University, University Park, Pennsylvania 16802 College of Materials Science and Engineering, Qingdao University of Science and Technology (QUST), 53 Zhengzhou Rd., Shibei District, Qingdao 266042, P. R. China Department of General Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi’an, Shaanxi, China Centre Léon Bérard, Plateforme de Génomique des Cancers, Département de la Recherche Translationnelle et d'Innovation Lyon France; Laboratoire de la Génétique Constitutionnelle des Cancers Fréquents HCL‐CLB Lyon France Department of Materials Science and Engineering, Faculty of Engineering, NUSNNI-Nanocore, National University of Singapore, 117576 Singapore Department of Oncology, Qujing First People's Hospital, China Department of Human Anatomy, Weifang Medical UniversityWeifang, Shandong, PR China. Faculty of Materials Science and Chemistry China University of Geosciences Wuhan 430074 P. R. China; Zhejiang Institute China University of Geosciences (Wuhan) Hangzhou 311305 P. R. China; Department of Materials Science and Engineering The Pennsylvania State University University Park Pennsylvania 16802 USA Department of Cardiology, Fuxing Hospital Affiliated to the Capital Medical University, Beijing 100038, China. wq1122@medmail.com.cn College of Chemistry and Chemical Engineering, Central South University School of Geographic Sciences; Key Laboratory of Geo-information of the Ministry of Education; East China Normal University; Shanghai; China Department of Pharmacology, Human Phenome Institute, School of Pharmacy, Fudan University, Shanghai, P.R. China Department of Materials Science and Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802, Department of Basic Science, Metropolitan Autonomous University, Azcapotzalco, Mexico City 02200, Mexico Department of Orthopaedics Kunshan Affiliated Hospital of Nanjing University of Chinese Medicine Kunshan Jiangsu China Key laboratory of vegetable postharvest processing Ministry of Agriculture Beijing Key Laboratory of Fruits and Vegetable Storage and Processing Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (North China) of Ministry of Agriculture Key Laboratory of Urban Agriculture (North) of Ministry of Agriculture Beijing Vegetable Research Center Beijing Academy of Agriculture and Forestry Sciences Beijing China Department of Obstetrics and Gynecology, First Affiliated Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, China Laboratory of Neural Signal Transduction Institute of Neuroscience Shanghai 200031 China; Graduate School of Chinese Academy of Sciences University of Chinese Academy of Sciences Shanghai 200031 China From the Department of Medicine, Madigan Army Medical Center, Tacoma, Washington; Peking University Department of Orthopedics; the First Affiliated Hospital of Nanjing Medical University; Nanjing China Dalian University of Technology, Panjin, China Department of Urology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 Hubei P. R. China School of Chemistry & Chemical Engineering, Beijing Institute of Technology (Liangxiang Campus), Beijing 102488, China Department of Orthopaedics; The First Affiliated Hospital of Soochow University; Suzhou; China Key Laboratory of Birth Defects Pediatrics Research Institute Children’s Hospital of Fudan University Shanghai China Department of Andrology Jiangsu Province Hospital of Chinese Medicine Affiliated Hospital of Nanjing University of Chinese Medicine Nanjing China Department of Rehabilitation Center of Wuhan Puren Hospital, Affiliated Hospital of Wuhan University of Science and Technology, Wuhan, China Department of Neurosurgery, Wuxi Second Hospital Affiliated to Nanjing Medical University, Wuxi, Jiangsu, China Department of Stomatology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 200080, P. R. China School of Chinese Materia Medica Beijing University of Chinese Medicine Beijing PR China Department of Physics, Nanchang University, Nanchang 330031, China Ludwig Center for Cancer Genetics and Therapeutics and; The Howard Hughes Medical Institute, Johns Hopkins Kimmel Cancer Center, Baltimore, MD21231; School of Materials Science and Engineering, Shandong University of Technology, Xincunxi Road 266th, Zibo 255000, China Laboratory for Photonics and Interfaces, Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland College of Chemistry and Molecular Sciences Wuhan University Wuhan 430072 P. R. China Fuzhou Institute of Product Quality Inspection; Fuzhou Fujian China International Joint Laboratory of Catalytic Chemistry, Department of Chemistry, Research Center of Nano Science and Technology, College of Sciences, Shanghai University, Shanghai 200444, People’s Republic of China School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, PR China; Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China, Zhengzhou 450001, PR China; Key Laboratory of Henan Province for Drug Quality and Evaluation, Zhengzhou 450001, PR China School of Basic Medicine, Peking Union Medical College, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China School of Nursing Ningxia Medical University Ningxia China Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse; School of Environmental and Biological Engineering; Nanjing University of Science and Technology; Nanjing 210094; People's Republic of China. State Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University , Qingdao, China College of Chemical Engineering Sichuan University Chengdu 610065 China Tea Research Institute, Guangdong Academy of Agricultural Sciences, Guangdong Provincial Key Laboratory of Tea Plant Resources Innovation and Utilization, Guangzhou 510640, China Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702 Obstetrics and Gynecology Hospital of Fudan University , Shanghai , China Department of Chemistry and Chemical Engineering; Henan Institute of Science and Technology; Xinxiang; China From the Center for Molecular Genetics, Department of Molecular Cardiology, Lerner Research Institute (C.O., L.W., L.L., J.D., S.R., W.D., Q.W.) and the Center for Cardiovascular Genetics, Department of Cardiovascular Medicine (C.O., L.W., L.L., J.D., S.R., W.D., Q.W.), The Cleveland Clinic Foundation; the Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University (L.W., L.L., J.D., S.R., Q.W.), and the Department of Biological, Geological, and... Department of Chemistry National University of Singapore 3 Science Drive 3 117543 Singapore Singapore Guangxi Key Laboratory of AIDS Prevention and Treatment & School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China; Guangxi Universities Key Laboratory of Prevention and Control of Highly Prevalent Disease, Nanning, 530021, Guangxi, China School of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu, 610500, China Department of Neurology; The Third Affiliated Hospital of Sun Yat-Sen University; Guangzhou Guangdong P. R. China Department of Radiology General Hospital of Tianjin Medical University Tianjin China State Key Laboratory of Petroleum Resources and Prospecting, China University of Petroleum at Beijing, Beijing 102249, China Department of Pharmacy, the Second Affiliated Hospital of Army Medical University, Chongqing, China Key Laboratory of Fishery Drug Development Ministry of Agriculture Key Laboratory of Aquatic Animal Immune Technology Pearl River Fisheries Research Institute Chinese Academy of Fishery Sciences Guangzhou China College of Life Sciences, Wuhan University, Wuhan 430072, China Department of Physics, University of Texas at Dallas 1 , 800 West Campbell Road, Richardson, Texas 75080, USA Shanghai Biotechnology Corporation, Shanghai, China and Department of Orthopaedics, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, Jiangsu Province Department of Pharmacy, Xiamen Medical College, Xiamen 361023, China; Xiamen Key Laboratory of Traditional Chinese Medicine Bioengineering, Xiamen Medical College, Xiamen 361023, China Engineering Research Centre of Oil Shale Comprehensive Utilization, Ministry of Education, Northeast Electric Power University, Jilin City 132012, China National Renewable Energy Laboratory, Golden, Colorado 80401-3393 College of Mechanical and Electronic Engineering Shandong University of Science and Technology Qingdao 266590 China State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Central Hospital of Gynecology Obstetrics/Tianjin Key Laboratory of Human Development and Reproductive Regulation Nankai University Tianjin China Key Laboratory of Jiangxi Province for Environment and Energy Catalysis, College of Chemistry, Nanchang University, Nanchang, Jiangxi 330031, P.R. China Research and Development Center for Efficient Utilization of Coastal Bioresources, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China State Key Laboratory of Agrobiotechnology and MOA Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural University, Beijing, P. R. China; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, P. R. China Department of Minimally Invasive Surgery, East Part of Suzhou Municipal Hospital of Nanjin Medical University, Suzhou 215001, China. From the Departments of Mechanical Engineering and Materials Science and Institute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Jiangsu National Synergetic Innovation Center for Advanced Materials Nanjing Tech University Nanjing 211816 P.R. China Department of Animal and Food Sciences, University of Delaware, Newark, Delaware, USA College of Chemistry and Molecular Sciences Wuhan University Wuhan P. R. China Division of Hematology-Oncology, School of Medicine and Department of Genetics, College of Life Sciences Wuhan University Wuhan China College of Pharmacy, Chongqing Medical University, Chongqing, P. R. China The Medical Department, 3D Medicines Inc, Shanghai, China State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou, China, and; Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou, China Affiliated Wuxi Second Hospital Nanjing Medical University Wuxi Jiangsu Province 214122 P. R. China; Affiliated Wuxi Clinical Medicine Nantong University Wuxi Jiangsu Province 214122 P. R. China Tianjin Key Laboratory for Photoelectric Materials and Devices; Department of Function Materials; School of Materials Science and Engineering; Tianjin University of Technology; Tianjin 300384 From LDS Hospital (L.Z., K.W.T., G.M.V., J.F., L.C.G., F.Y.), Salt Lake City, Utah; University of Utah School of Medicine (G.M.V., S.J.C., J.S., I.S, F.Y., M.T.K.), Salt Lake City; University of Michigan (M.H.L.), Ann Arbor; Molecular Cardiology (S.G.P.), Maugeri Foundation, Pavia, Italy; Bikur Cholim Hospital (J.B., A.M.), Jerusalem, Israel; University of Rochester School of Medicine and Dentistry (A.J.M., J.L.R., W.Z.), Rochester, NY; Policlinico S. Matteo IRCCS (P.J.S., C.N.), Milan, Italy;... 1Ludwig Center, Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland.; 2Howard Hughes Medical Institute, Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland. Function Experiment Teaching Center, Wenzhou Medical University, Wenzhou, Zhejiang 325305, P.R. China State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious Diseases Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases The First Affiliated Hospital College of Medicine Zhejiang University Hangzhou 310003 China Anhui Key Laboratory of Condensed Matter Physics at Extreme Conditions High Magnetic Field Laboratory HFIPS Anhui Chinese Academy of Sciences Hefei 230031 China School of Nursing, Nanjing University of Chinese Medicine, Nanjing 210023, China Xicheng District Centre for Diseases Control and Prevention, Beijing, China Department of Preventive Veterinary Medicine, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China. *Corresponding authors, E-mail: qingwang@ahau.edu.cn. Department of Mechanical Engineering, Washington University, St. Louis, Missouri. School of Pharmacy Henan University of Chinese Medicine Zhengzhou China Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110003, P.R. China Department of Neurology, University of California, Los Angeles, CA 90095, USA.; Department of Radiology, University of California, Los Angeles, CA 90095, USA.; Interdepartmental Program in Neurosciences, University of California, Los Angeles, CA 90095, USA.; Department of Ophthalmology, University of California, Los Angeles, CA 90095, USA.; Department of Human Genetics, University of California, Los Angeles, CA 90095, USA. School of Traditional Chinese Medicine Beijing University of Chinese Medicine Beijing China QiLu Hospital, Shandong University, Jinan, China Department of Gastroenterology, Qilu Hospital(Qingdao), Cheeloo College of Medicine, Shangdong University From the ∗ , 758 Hefei Road, Qingdao, Shangdong , China Center for Molecular Genetics, Department of Molecular Cardiology, Cleveland Clinic Foundation, Cleveland 44195; Center for Cardiovascular Genetics, Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland 44195; Department of Biology, Cleveland State University, Cleveland 44115 Department of General Surgery Zibo Central Hospital Zibo China Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200233, China Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China National University of Singapore Department of Materials Science & Engineering Singapore 117576 Singapore Department of Neurology, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong 510282, China State Key Laboratory of Natural Medicines, Key Laboratory of Drug Quality Control and Pharmacovigilance, Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 210009, China Institute of Botany, Jiangsu Province & Chinese Academy of Sciences, Nanjing, China. College of Chemical Engineering Sichuan University Chengdu 610065 People's Republic of China Rutgers-New Jersey Medical School, Newark, NJ, USA Contribution from the Laboratory for Photonics and Interfaces, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland, and HPL SA, CH-1015 Lausanne, Switzerland Nanjing Fisheries Research Institute, 210029, Nanjing, China School of Chinese Pharmacy; Beijing University of Chinese Medicine; Beijing China Institute of Medical Information, School of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong 510515, China. for the Dominantly Inherited Alzheimer Network and the Alzheimer’s Disease Neuroimaging Initiative Center for Cardiovascular Genetics, Department of Cardiovascular Medicine, and Center for Molecular Genetics, Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic Foundation; Department of Molecular Medicine; Department of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA. State Key Laboratory of Hybrid Rice College of Life Sciences Wuhan University Wuhan 430072 China Division of HIV/AIDS and Sexually Transmitted Virus Vaccines, National Institutes for Food and Drug Control (NIFDC), Beijing, People’s Republic of China Endoscopy Center, Integrated Chinese and Western Medicine Hospital, Tianjin University, Tianjin, China;; Department of Hepatopancreatobiliary Surgery, Integrated Chinese and Western Medicine Hospital, Tianjin University, Tianjin, China Center for Cardiovascular Genetics, Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, U.S.A.; Key Laboratory of Molecular Biophysics of the Ministry of Education, Cardio-X Institute, College of Life Science and Technology and Center of Human Genome Research, Huazhong University of Science and Technology, Wuhan 430074, China Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Department of Chemistry, Wuhan University, Wuhan, Hubei 430072, People’s Republic of China Department of Thoracic Surgery Tengzhou Central People's Hospital Tengzhou City Shandong Province PR China From Duke University Medical Center (H.S.Q., V.N., S.E.G.), Durham, NC; Department of Cardiovascular Medicine (K.C.), John Radcliffe Hospital, Oxford, UK; and Cell Genesys Inc (Q.W., M.F., L.T., J.M.), Foster City, Calif. Tsinghua National Laboratory for Information Science and Technology, Tsinghua University, Beijing, China State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China (mainland) Justus Liebig University Giessen; Department of Plant Breeding; IFZ; Justus Liebig University Giessen; 35392 Giessen Department of Laboratory Medicine Karolinska Institutet Stockholm Sweden Beijing Hi-LongCare Medicine & Technology Co., Ltd., Beijing, People’s Republic of China State Key Laboratory of Natural and Biomimetic Drugs; School of Pharmaceutical Sciences; Peking University; Beijing 100191; People's Republic of China Shenzhen Key Laboratory of Special Functional Materials, Shenzhen Engineering Laboratory for Advanced Technology of Ceramics, Guangdong Research Center for Interfacial Engineering of Functional Materials, and College of Materials Science and Engineering, Shenzhen University, Shenzhen 518055, China Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430000, P. R. China Department of Thoracic Surgery The Fourth Affiliated Hospital of China Medical University Shenyang Liaoning 110032 China Hutchison MediPharma Limited, Building 4, 720 Cai Lun Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China Department of Radiology Third Affiliated Hospital of Soochow University & Changzhou First People's Hospital Changzhou Jiangsu China 1Department of Toxicology, School of Public Health, Sun Yat-sen University, Guangzhou, People’s Republic of China; 3Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Guangzhou, People’s Republic of China Wuxi Hupper Seed Technology Research Co. Ltd. Huashan Hospital, Fudan University, Shanghai, China CAS Key Laboratory of Soil Environment and Pollution Remediation, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, Jiangsu, China. Mallinckrodt Institute of Radiology, Division of Neuroradiology, Washington University in St. Louis, St. Louis, MO, USA Department of Biliary-Pancreatic Minimally Invasive Surgery, The First Affiliated Hospital of Shantou University Medical College, Shantou 515041, Guangdong, China Department of Cardiology, Tianjin Medical University General Hospital, Tianjin 300052, China Department of Environmental Health Risk Assessment, China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China Bengbu Peace Eye Hospital, Bengbu, Anhui Province - China CAS Key Laboratory of Materials for Energy Conversion, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, P. R. China; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Science, Beijing 100049, P. R. China Wuxi Hupper Bioseed Technology Institute Ltd Wuxi 214000 Jiangsu China Dimitrios Zardavas and Debora Fumagalli, Breast International Group; Christos Sotiriou, Université Libre de Bruxelles, Brussels, Belgium; Luc te Marvelde and Roger L. Milne, Cancer Council; Roger L. Milne and Sherene Loi, University of Melbourne, Melbourne; Barry Iacopetta, University of Western Australia, Western Australia; Sandra O’Toole and Elena Lopez-Knowles, Garvan Institute of Medical Research, Darlinghurst, Australia; George Fountzilas and Vassiliki Kotoula, Hellenic Foundation for Cancer... College of Life Sciences Wuhan University Wuhan China School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine Guangzhou China Department of Pharmacy, China National Clinical Research Center of Kidney Diseases, Affiliated Jinling Hospital, Medical School of Nanjing University , Nanjing, China Department of Neurosurgery, the Affiliated Wuxi No. 2 People’s Hospital of Nanjing Medical University, Wuxi, China College of Chemistry Beijing Normal University Beijing China College of Chemical Engineering; Sichuan University; Chengdu; China Key Laboratory of Vegetable Postharvest Processing, Ministry of Agriculture and Rural Affairs, Beijing Key Laboratory of Fruits and Vegetable Storage and Processing, Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (North China) of Ministry of Agriculture, Key Laboratory of Urban Agriculture (North) of Ministry of Agriculture, Institute of Agri-food Processing and Nutrition, Beijing Vegetable Research Center, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China School of Materials Science and Engineering, Northeastern University, Shenyang 110819, PR China; School of Resources and Materials, Northeastern University at Qinhuangdao, Qinhuangdao 066004, PR China; Key Laboratory of Dielectric and Electrolyte Functional Material Hebei Province, Qinhuangdao 066004, PR China Department of Materials Science and Engineering National University of Singapore Singapore 117574 Singapore State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Changsha 410082, China City University of Hong Kong 2 Centre for Advanced Structural Materials, Department of Mechanical and Biomedical Engineering, , Kowloon, Hong Kong, China; Institute of Materials Science, Shanghai University 4 Laboratory for Microstructures, , Shanghai 200072, China State Grid Hebei Electric Power Research Institute, Shijiazhuang 050021, China; State Grid Hebei Energy Technology Service Co., Ltd., Shijiazhuang 050021, China Department of Bioengineering, College of Life Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, P.R. China Key Laboratory of Coastal Zone Environmental Processes and Ecological Remediation, CAS, Shandong Provincial Key Laboratory of Coastal Environmental Processes, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, China Department of Stomatology Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200080 China Department of Immunology, Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou, China; Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, China Department of Thoracic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine Shanghai 200217, China. Department of Endocrinology |
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